Published in Sci Signal on September 23, 2014
Transcription factor SPZ1 promotes TWIST-mediated epithelial-mesenchymal transition and oncogenesis in human liver cancer. Oncogene (2017) 1.39
Notch signaling and EMT in non-small cell lung cancer: biological significance and therapeutic application. J Hematol Oncol (2014) 1.20
Noncanonical role of transferrin receptor 1 is essential for intestinal homeostasis. Proc Natl Acad Sci U S A (2015) 0.93
Epithelial Mesenchymal Transition: a double-edged sword. Clin Transl Med (2015) 0.92
The evolving roles of canonical WNT signaling in stem cells and tumorigenesis: implications in targeted cancer therapies. Lab Invest (2015) 0.91
ZEB1 Mediates Acquired Resistance to the Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer. PLoS One (2016) 0.91
Regulation of epithelial-mesenchymal transition through epigenetic and post-translational modifications. Mol Cancer (2016) 0.90
Long non-coding RNA urothelial cancer-associated 1 promotes bladder cancer cell migration and invasion by way of the hsa-miR-145-ZEB1/2-FSCN1 pathway. Cancer Sci (2015) 0.89
Acquisition of resistance to trastuzumab in gastric cancer cells is associated with activation of IL-6/STAT3/Jagged-1/Notch positive feedback loop. Oncotarget (2015) 0.89
β-arrestin-1 mediates nicotine-induced metastasis through E2F1 target genes that modulate epithelial-mesenchymal transition. Cancer Res (2015) 0.88
New Insights into the Crossroads between EMT and Stemness in the Context of Cancer. J Clin Med (2016) 0.88
HOXD9 promotes epithelial-mesenchymal transition and cancer metastasis by ZEB1 regulation in hepatocellular carcinoma. J Exp Clin Cancer Res (2015) 0.86
DKK3 blocked translocation of β-catenin/EMT induced by hypoxia and improved gemcitabine therapeutic effect in pancreatic cancer Bxpc-3 cell. J Cell Mol Med (2015) 0.85
Wnt signaling through Snail1 and Zeb1 regulates bone metastasis in lung cancer. Am J Cancer Res (2015) 0.84
Ginsenoside Rg3 inhibits epithelial-mesenchymal transition (EMT) and invasion of lung cancer by down-regulating FUT4. Oncotarget (2016) 0.84
YPEL3 suppresses epithelial-mesenchymal transition and metastasis of nasopharyngeal carcinoma cells through the Wnt/β-catenin signaling pathway. J Exp Clin Cancer Res (2016) 0.84
Salidroside protects against bleomycin-induced pulmonary fibrosis: activation of Nrf2-antioxidant signaling, and inhibition of NF-κB and TGF-β1/Smad-2/-3 pathways. Cell Stress Chaperones (2015) 0.83
Mechanisms of TGFβ-Induced Epithelial-Mesenchymal Transition. J Clin Med (2016) 0.82
HIF-1α regulates EMT via the Snail and β-catenin pathways in paraquat poisoning-induced early pulmonary fibrosis. J Cell Mol Med (2016) 0.82
Menstrual physiology: implications for endometrial pathology and beyond. Hum Reprod Update (2015) 0.82
Editorial: Cellular and Phenotypic Plasticity in Cancer. Front Oncol (2015) 0.82
Invasive mouse gastric adenocarcinomas arising from Lgr5+ stem cells are dependent on crosstalk between the Hedgehog/GLI2 and mTOR pathways. Oncotarget (2016) 0.82
Endothelial to Mesenchymal Transition (EndoMT) in the Pathogenesis of Human Fibrotic Diseases. J Clin Med (2016) 0.82
Epithelial-to-Mesenchymal Plasticity Harnesses Endocytic Circuitries. Front Oncol (2015) 0.82
Breast cancer cells promote a notch-dependent mesenchymal phenotype in endothelial cells participating to a pro-tumoral niche. J Transl Med (2015) 0.81
CPEB1 mediates epithelial-to-mesenchyme transition and breast cancer metastasis. Oncogene (2015) 0.81
Mesenchymal stem cells promote pancreatic adenocarcinoma cells invasion by transforming growth factor-β1 induced epithelial-mesenchymal transition. Oncotarget (2016) 0.80
Epithelial-to-Mesenchymal Transition in the Pathogenesis and Therapy of Head and Neck Cancer. Cancers (Basel) (2017) 0.80
Noncoding RNAs in Tumor Epithelial-to-Mesenchymal Transition. Stem Cells Int (2016) 0.80
Expression of TWIST, an inducer of epithelial-mesenchymal transition, in nasopharyngeal carcinoma and its clinical significance. Int J Clin Exp Pathol (2014) 0.80
Cyclin G2 inhibits epithelial-to-mesenchymal transition by disrupting Wnt/β-catenin signaling. Oncogene (2016) 0.80
The tumor microenvironment: An irreplaceable element of tumor budding and epithelial-mesenchymal transition-mediated cancer metastasis. Cell Adh Migr (2016) 0.80
SHP-2-upregulated ZEB1 is important for PDGFRα-driven glioma epithelial-mesenchymal transition and invasion in mice and humans. Oncogene (2016) 0.80
ANGPTL4 Correlates with NSCLC Progression and Regulates Epithelial-Mesenchymal Transition via ERK Pathway. Lung (2016) 0.80
Epithelial-to-Mesenchymal Transition and Cancer Invasiveness: What Can We Learn from Cholangiocarcinoma? J Clin Med (2015) 0.79
A Histone Deacetylase Inhibitor Suppresses Epithelial-Mesenchymal Transition and Attenuates Chemoresistance in Biliary Tract Cancer. PLoS One (2016) 0.79
Over-expression of TWIST, an epithelial-mesenchymal transition inducer, predicts poor survival in patients with oral carcinoma. Int J Clin Exp Med (2015) 0.79
Notch in fibrosis and as a target of anti-fibrotic therapy. Pharmacol Res (2016) 0.79
Expression and clinical significance of microvessel density and its association with TWIST in nasopharyngeal carcinoma. Int J Clin Exp Med (2015) 0.79
MiR-223 inhibited cell metastasis of human cervical cancer by modulating epithelial-mesenchymal transition. Int J Clin Exp Pathol (2015) 0.79
Multifunctional DDX3: dual roles in various cancer development and its related signaling pathways. Am J Cancer Res (2016) 0.79
Revisiting Epithelial-to-Mesenchymal Transition in Liver Fibrosis: Clues for a Better Understanding of the "Reactive" Biliary Epithelial Phenotype. Stem Cells Int (2016) 0.78
FERMT1 mediates epithelial-mesenchymal transition to promote colon cancer metastasis via modulation of β-catenin transcriptional activity. Oncogene (2016) 0.78
MicroRNA-20a-5p promotes colorectal cancer invasion and metastasis by downregulating Smad4. Oncotarget (2016) 0.78
The Hedgehog Inhibitor Cyclopamine Reduces β-Catenin-Tcf Transcriptional Activity, Induces E-Cadherin Expression, and Reduces Invasion in Colorectal Cancer Cells. Cancers (Basel) (2015) 0.78
DMXL2 drives epithelial to mesenchymal transition in hormonal therapy resistant breast cancer through Notch hyper-activation. Oncotarget (2015) 0.78
Fibulin-5 inhibits Wnt/β-catenin signaling in lung cancer. Oncotarget (2015) 0.78
Palmitoylated claudin7 captured in glycolipid-enriched membrane microdomains promotes metastasis via associated transmembrane and cytosolic molecules. Oncotarget (2016) 0.78
Long-term reduction of T-cell intracellular antigens reveals a transcriptome associated with extracellular matrix and cell adhesion components. PLoS One (2014) 0.78
Ubiquitin ligase UBE3C promotes melanoma progression by increasing epithelial-mesenchymal transition in melanoma cells. Oncotarget (2016) 0.78
The Cdc42/Rac1 regulator CdGAP is a novel E-cadherin transcriptional co-repressor with Zeb2 in breast cancer. Oncogene (2017) 0.78
Aspirin-Triggered Resolvin D1 Inhibits TGF-β1-Induced EndMT through Increasing the Expression of Smad7 and Is Closely Related to Oxidative Stress. Biomol Ther (Seoul) (2016) 0.78
Aberrant expression of Notch1/numb/snail signaling, an epithelial mesenchymal transition related pathway, in adenomyosis. Reprod Biol Endocrinol (2015) 0.77
BMP signaling and its paradoxical effects in tumorigenesis and dissemination. Oncotarget (2016) 0.77
Expression and significance of TWIST, a zinc finger transcription factor, in laryngeal carcinoma among Chinese population: a meta-analysis. Int J Clin Exp Med (2015) 0.77
14-3-3σ Gene Loss Leads to Activation of the Epithelial to Mesenchymal Transition Due to the Stabilization of c-Jun Protein. J Biol Chem (2016) 0.77
ShcA Protects against Epithelial-Mesenchymal Transition through Compartmentalized Inhibition of TGF-β-Induced Smad Activation. PLoS Biol (2015) 0.77
Aberrant over-expression of COX-1 intersects multiple pro-tumorigenic pathways in high-grade serous ovarian cancer. Oncotarget (2015) 0.77
Role of microRNAs in gastrointestinal smooth muscle fibrosis and dysfunction: novel molecular perspectives on the pathophysiology and therapeutic targeting. Am J Physiol Gastrointest Liver Physiol (2016) 0.77
Eukaryotic translation initiation factor 5A2 regulates the migration and invasion of hepatocellular carcinoma cells via pathways involving reactive oxygen species. Oncotarget (2016) 0.77
Fluid shear stress induces epithelial-mesenchymal transition (EMT) in Hep-2 cells. Oncotarget (2016) 0.77
Ubiquitin-specific protease 4 controls metastatic potential through β-catenin stabilization in brain metastatic lung adenocarcinoma. Sci Rep (2016) 0.77
Casein kinase 1γ ensures monopolar growth polarity under incomplete DNA replication downstream of Cds1 and calcineurin in fission yeast. Mol Cell Biol (2015) 0.77
Ouabain promotes partial epithelial to mesenchymal transition (EMT) changes in human autosomal dominant polycystic kidney disease (ADPKD) cells. Exp Cell Res (2017) 0.76
microRNAs regulate β-catenin of the Wnt signaling pathway in early sea urchin development. Dev Biol (2015) 0.76
Paracrine Met signaling triggers epithelial-mesenchymal transition in mammary luminal progenitors, affecting their fate. Elife (2015) 0.76
Cancer cells remodel themselves and vasculature to overcome the endothelial barrier. Cancer Lett (2014) 0.76
Endothelial-Mesenchymal Transition in Regenerative Medicine. Stem Cells Int (2016) 0.76
Endothelial-mesenchymal transition in atherosclerotic lesion calcification. Atherosclerosis (2016) 0.76
Endothelial Mesenchymal Transition: Comparative Analysis of Different Induction Methods. Biol Proced Online (2016) 0.76
DDA1 promotes stage IIB-IIC colon cancer progression by activating NFκB/CSN2/GSK-3β signaling. Oncotarget (2016) 0.76
TGFβ Pathway Inhibition Redifferentiates Human Pancreatic Islet β Cells Expanded In Vitro. PLoS One (2015) 0.76
DAB2IP in cancer. Oncotarget (2016) 0.76
Gli promotes epithelial-mesenchymal transition in human lung adenocarcinomas. Oncotarget (2016) 0.76
Inhibitory Effect of Bone Morphogenetic Protein 4 in Retinal Pigment Epithelial-Mesenchymal Transition. Sci Rep (2016) 0.76
Antibiotic drug tigecycline inhibits melanoma progression and metastasis in a p21CIP1/Waf1-dependent manner. Oncotarget (2016) 0.76
The co-stimulatory molecule B7-H3 promotes the epithelial-mesenchymal transition in colorectal cancer. Oncotarget (2016) 0.76
The Mitochondrial Complex(I)ty of Cancer. Front Oncol (2017) 0.75
Is overexpression of TWIST, a transcriptional factor, a prognostic biomarker of head and neck carcinoma? Evidence from fifteen studies. Sci Rep (2015) 0.75
Epithelial-Mesenchymal Transition is Superior to Vessels-Encapsulate Tumor Cluster in Promoting Metastasis of Hepatocellular Carcinoma: a Morphological Evidence. J Cancer (2017) 0.75
Allicin inhibits tubular epithelial-myofibroblast transdifferentiation under high glucose conditions in vitro. Exp Ther Med (2016) 0.75
FAM83 proteins: Fostering new interactions to drive oncogenic signaling and therapeutic resistance. Oncotarget (2016) 0.75
AECHL-1 targets breast cancer progression via inhibition of metastasis, prevention of EMT and suppression of Cancer Stem Cell characteristics. Sci Rep (2016) 0.75
Integrated functions of membrane-type 1 matrix metalloproteinase in regulating cancer malignancy: beyond a proteinase. Cancer Sci (2017) 0.75
Macrophages programmed by apoptotic cells inhibit epithelial-mesenchymal transition in lung alveolar epithelial cells via PGE2, PGD2, and HGF. Sci Rep (2016) 0.75
HIF-1α induces the epithelial-mesenchymal transition in gastric cancer stem cells through the Snail pathway. Oncotarget (2017) 0.75
Daxx inhibits hypoxia-induced lung cancer cell metastasis by suppressing the HIF-1α/HDAC1/Slug axis. Nat Commun (2016) 0.75
Upregulation of neurovascular communication through filamin abrogation promotes ectopic periventricular neurogenesis. Elife (2016) 0.75
miR-4775 promotes colorectal cancer invasion and metastasis via the Smad7/TGFβ-mediated epithelial to mesenchymal transition. Mol Cancer (2017) 0.75
Downregulation of Lnc-Spry1 mediates TGF-β-induced epithelial-mesenchymal transition by transcriptional and posttranscriptional regulatory mechanisms. Cell Death Differ (2017) 0.75
Molecular Profiling of the Developing Lacrimal Gland Reveals Putative Role of Notch Signaling in Branching Morphogenesis. Invest Ophthalmol Vis Sci (2017) 0.75
Epithelial to mesenchymal transition-related proteins ZEB1, β-catenin, and β-tubulin-III in idiopathic pulmonary fibrosis. Mod Pathol (2016) 0.75
Ataxin-1 regulates epithelial-mesenchymal transition of cervical cancer cells. Oncotarget (2017) 0.75
Manganese superoxide dismutase promotes interaction of actin, S100A4 and Talin, and enhances rat gastric tumor cell invasion. J Clin Biochem Nutr (2015) 0.75
Epithelial-mesenchymal transition in prostate cancer: an overview. Oncotarget (2017) 0.75
Ribosomal L22-like1 (RPL22L1) Promotes Ovarian Cancer Metastasis by Inducing Epithelial-to-Mesenchymal Transition. PLoS One (2015) 0.75
Centrosome - a promising anti-cancer target. Biologics (2016) 0.75
Involvement of heparanase in the pathogenesis of acute kidney injury: nephroprotective effect of PG545. Oncotarget (2017) 0.75
Dual function of TGFβ in lens epithelial cell fate: implications for secondary cataract. Mol Biol Cell (2017) 0.75
Interleukin‑6 induces epithelial‑mesenchymal transition in human intrahepatic biliary epithelial cells. Mol Med Rep (2015) 0.75
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