Regulation of exocytosis from rat peritoneal mast cells by G protein beta gamma-subunits.

PubWeight™: 0.91‹?›

🔗 View Article (PMC 1170947)

Published in EMBO J on November 02, 1998

Authors

J A Pinxteren1, A J O'Sullivan, P E Tatham, B D Gomperts

Author Affiliations

1: Secretory Mechanisms Group, Department of Physiology, University College London, University Street, London WC1E 6JJ, UK.

Articles cited by this

Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci U S A (1979) 365.71

Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa. Anal Biochem (1987) 59.79

A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002). J Biol Chem (1994) 14.36

Calcium ionophores and movement of calcium ions following the physiological stimulus to a secretory process. Nature (1973) 6.09

Capacitance measurements reveal stepwise fusion events in degranulating mast cells. Nature (1985) 5.41

Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate. Nature (1994) 4.49

Roles of G protein subunits in transmembrane signalling. Nature (1988) 4.16

Calcium-dependent activation of a multifunctional protein kinase by membrane phospholipids. J Biol Chem (1979) 4.12

ATP-dependent inositide phosphorylation required for Ca(2+)-activated secretion. Nature (1995) 3.30

The guanine nucleotide activating site of the regulatory component of adenylate cyclase. Identification by ligand binding. J Biol Chem (1982) 3.09

Regulation of Gi and Go by mastoparan, related amphiphilic peptides, and hydrophobic amines. Mechanism and structural determinants of activity. J Biol Chem (1990) 2.96

Binding of G protein beta gamma-subunits to pleckstrin homology domains. J Biol Chem (1994) 2.91

New roles for G-protein beta gamma-dimers in transmembrane signalling. Nature (1993) 2.66

Lysolipids reversibly inhibit Ca(2+)-, GTP- and pH-dependent fusion of biological membranes. FEBS Lett (1993) 2.11

GE: a GTP-binding protein mediating exocytosis. Annu Rev Physiol (1990) 2.08

Essential synergy between Ca2+ and guanine nucleotides in exocytotic secretion from permeabilized rat mast cells. J Cell Biol (1987) 2.05

Guanine nucleotides induce Ca2+-independent insulin secretion from permeabilized RINm5F cells. J Biol Chem (1987) 1.99

Evidence that the inositol phospholipids are necessary for exocytosis. Loss of inositol phospholipids and inhibition of secretion in permeabilized cells caused by a bacterial phospholipase C and removal of ATP. Biochem J (1990) 1.66

IgE-induced tyrosine phosphorylation of phospholipase C-gamma 1 in rat basophilic leukemia cells. J Biol Chem (1991) 1.66

Rat mast cells permeabilised with streptolysin O secrete histamine in response to Ca2+ at concentrations buffered in the micromolar range. Biochim Biophys Acta (1987) 1.63

Expression cloning of lfc, a novel oncogene with structural similarities to guanine nucleotide exchange factors and to the regulatory region of protein kinase C. J Biol Chem (1995) 1.56

The receptor with high affinity for IgE. Immunol Rev (1992) 1.53

Activation of exocytosis by the heterotrimeric G protein Gi3. Science (1993) 1.43

Myristoylation of G-protein alpha subunits. Methods Enzymol (1994) 1.40

Techniques and concepts in exocytosis: focus on mast cells. Biochim Biophys Acta (1991) 1.37

Signaling from G protein-coupled receptors to c-Jun kinase involves beta gamma subunits of heterotrimeric G proteins acting on a Ras and Rac1-dependent pathway. J Biol Chem (1996) 1.32

Ionomycin stimulates mast cell histamine secretion by forming a lipid-soluble calcium complex. Nature (1980) 1.31

Retroviral transduction and oncogenic selection of a cDNA encoding Dbs, a homolog of the Dbl guanine nucleotide exchange factor. Oncogene (1995) 1.25

Protein phosphorylation and the dependence on Ca2+ and GTP-gamma-S for exocytosis from permeabilised mast cells. Cell Signal (1989) 1.20

Pleckstrin homology domains: a fact file. Curr Opin Struct Biol (1995) 1.19

Mutational analysis of the pleckstrin homology domain of the beta-adrenergic receptor kinase. Differential effects on G beta gamma and phosphatidylinositol 4,5-bisphosphate binding. J Biol Chem (1995) 1.18

Exocytosis in mast cells by basic secretagogues: evidence for direct activation of GTP-binding proteins. J Cell Biol (1990) 1.16

Direct control of exocytosis by receptor-mediated activation of the heterotrimeric GTPases Gi and G(o) or by the expression of their active G alpha subunits. EMBO J (1995) 1.15

Effects of ADP-ribosylation of GTP-binding protein by pertussis toxin on immunoglobulin E-dependent and -independent histamine release from mast cells and basophils. J Immunol (1987) 1.14

A key role for a 145-kDa cytosolic protein in the stimulation of Ca(2+)-dependent secretion by protein kinase C. J Biol Chem (1992) 1.09

The N terminus of phosducin is involved in binding of beta gamma subunits of G protein. Proc Natl Acad Sci U S A (1995) 1.09

Specificity of action of guanine nucleotide-binding regulatory protein subunits on the cardiac muscarinic K+ channel. Proc Natl Acad Sci U S A (1988) 1.07

Induction of exocytosis from permeabilized mast cells by the guanosine triphosphatases Rac and Cdc42. Mol Biol Cell (1998) 1.07

Synthetic peptides as probes for G protein function. Carboxyl-terminal G alpha s peptides mimic Gs and evoke high affinity agonist binding to beta-adrenergic receptors. J Biol Chem (1994) 1.07

Expression and purification of functional G protein alpha subunits using a baculovirus expression system. J Biol Chem (1992) 1.04

Regulated exocytotic secretion from permeabilized cells. Methods Enzymol (1992) 1.03

The stimulatory effect of calpactin (annexin II) on calcium-dependent exocytosis in chromaffin cells: requirement for both the N-terminal and core domains of p36 and ATP. Cell Signal (1990) 1.02

Rho guanine nucleotide dissociation inhibitor protein (RhoGDI) inhibits exocytosis in mast cells. EMBO J (1996) 1.01

Specific enhancement of beta-adrenergic receptor kinase activity by defined G-protein beta and gamma subunits. Proc Natl Acad Sci U S A (1993) 1.00

Purification and identification of FOAD-II, a cytosolic protein that regulates secretion in streptolysin-O permeabilized mast cells, as a rac/rhoGDI complex. Mol Biol Cell (1996) 0.99

Depletion of guanine nucleotides with mycophenolic acid suppresses IgE receptor-mediated degranulation in rat basophilic leukemia cells. J Immunol (1989) 0.97

Guanine nucleotide is essential and Ca2+ is a modulator in the exocytotic reaction of permeabilized rat mast cells. Biochem J (1992) 0.94

Ribavirin inhibits mast cell mediator release. J Pharmacol Exp Ther (1987) 0.93

Mastoparan stimulates exocytosis at a Ca(2+)-independent late site in stimulus-secretion coupling. Studies with the RINm5F beta-cell line. J Biol Chem (1993) 0.90

Mastoparan stimulates insulin secretion from pancreatic beta-cells by effects at a late stage in the secretory pathway. Mol Cell Endocrinol (1993) 0.89

Neomycin is a potent secretagogue of mast cells that directly activates a GTP-binding protein involved in exocytosis. J Cell Biol (1990) 0.88

Evidence for protein dephosphorylation as a permissive step in GTP-gamma-S-induced exocytosis from permeabilized mast cells. Cell Regul (1990) 0.86

Practical considerations regarding the use of streptolysin-O as a permeabilising agent for cells in the investigation of exocytosis. Biosci Rep (1996) 0.82

Tetanus toxin and Clostridium perfringens enterotoxin as tools for the study of exocytosis. Ann N Y Acad Sci (1994) 0.81

G-protein betagamma-binding domains regulate insulin exocytosis in clonal pancreatic beta-cells. FEBS Lett (1998) 0.79

Rat mast cells degranulate in response to microinjection of guanine nucleotide. J Cell Sci (1991) 0.79

Purification and properties of recombinant Rho-GDP dissociation inhibitor. Methods Enzymol (1995) 0.76

Articles by these authors

Calcium ionophores and movement of calcium ions following the physiological stimulus to a secretory process. Nature (1973) 6.09

Diagnosis of growth-hormone deficiency in adults. Lancet (1994) 5.93

Capacitance measurements reveal stepwise fusion events in degranulating mast cells. Nature (1985) 5.41

Role of guanine nucleotide binding protein in the activation of polyphosphoinositide phosphodiesterase. Nature (1985) 5.10

Involvement of guanine nucleotide-binding protein in the gating of Ca2+ by receptors. Nature (1983) 3.21

Two roles for guanine nucleotides in the stimulus-secretion sequence of neutrophils. Nature (1986) 2.50

ATP induces nucleotide permeability in rat mast cells. Nature (1979) 2.05

Essential synergy between Ca2+ and guanine nucleotides in exocytotic secretion from permeabilized rat mast cells. J Cell Biol (1987) 2.05

Distribution of two distinct Ca2+-ATPase-like proteins and their relationships to the agonist-sensitive calcium store in adrenal chromaffin cells. Nature (1989) 1.81

A possible role for cyclic AMP in the regulation of histamine secretion and the action of cromoglycate. Biochem Pharmacol (1975) 1.80

Two G-proteins act in series to control stimulus-secretion coupling in mast cells: use of neomycin to distinguish between G-proteins controlling polyphosphoinositide phosphodiesterase and exocytosis. J Cell Biol (1987) 1.75

Activation and inhibition of calcium-dependent histamine secretion by ATP ions applied to rat mast cells. J Physiol (1979) 1.70

The ATP4- receptor of rat mast cells. Biochem J (1980) 1.67

Mechanism of Ca2+ wave propagation in pancreatic acinar cells. J Biol Chem (1992) 1.66

Rat mast cells permeabilised with streptolysin O secrete histamine in response to Ca2+ at concentrations buffered in the micromolar range. Biochim Biophys Acta (1987) 1.63

Use of cytochalasin B to distinguish between early and late events in neutrophil activation. Biochim Biophys Acta (1980) 1.56

Rat mast cells permeabilized with ATP secrete histamine in response to calcium ions buffered in the micromolar range. J Physiol (1981) 1.52

Stimulus-secretion coupling in rabbit neutrophils is not mediated by phosphatidylinositol breakdown. Nature (1980) 1.47

Evidence for a role of phosphatidylinositol turnover in stimulus-secretion coupling. Studies with rat peritoneal mast cells. Biochem J (1979) 1.47

Effect of flavone inhibitors of transport ATPases on histamine secretion from rat mast cells. Nature (1977) 1.43

A major role for protein kinase C in calcium-activated exocytosis in permeabilised adrenal chromaffin cells. FEBS Lett (1988) 1.42

Investigation of early T cell activation: analysis of the effect of specific antigen, interleukin 2 and monoclonal antibodies on intracellular free calcium concentration. Eur J Immunol (1985) 1.41

The dependence on Ca2+ of phosphatidylinositol breakdown and enzyme secretion in rabbit neutrophils stimulated by formylmethionyl-leucylphenylalanine or ionomycin. Biochem J (1981) 1.41

Differential control of azurophilic and specific granule exocytosis in Sendai-virus-permeabilized rabbit neutrophils. J Physiol (1987) 1.37

Techniques and concepts in exocytosis: focus on mast cells. Biochim Biophys Acta (1991) 1.37

Quercetin: a novel inhibitor of Ca2+ influx and exocytosis in rat peritoneal mast cells. Biochim Biophys Acta (1977) 1.37

Ionomycin stimulates mast cell histamine secretion by forming a lipid-soluble calcium complex. Nature (1980) 1.31

Simultaneous measurements of cytosolic calcium and secretion in single bovine adrenal chromaffin cells by fluorescent imaging of fura-2 in cocultured cells. J Cell Biol (1989) 1.27

Changes in the state of actin during the exocytotic reaction of permeabilized rat mast cells. J Cell Biol (1990) 1.27

Spatial localization of the stimulus-induced rise in cytosolic Ca2+ in bovine adrenal chromaffin cells. Distinct nicotinic and muscarinic patterns. FEBS Lett (1989) 1.25

Characterisation of the ATP4- receptor that mediates permeabilisation of rat mast cells. Eur J Pharmacol (1988) 1.24

Wave-length dependencies of light scattering in normal and cold swollen rabbit corneas and their structural implications. J Physiol (1973) 1.24

f-MetLeuPhe-induced phosphatidylinositol turnover in rabbit neutrophils is dependent on extracellular calcium. FEBS Lett (1980) 1.21

Protein phosphorylation and the dependence on Ca2+ and GTP-gamma-S for exocytosis from permeabilised mast cells. Cell Signal (1989) 1.20

Breakdown and synthesis of polyphosphoinositides in fMetLeuPhe-stimulated neutrophils. FEBS Lett (1985) 1.18

The control of cytoskeletal actin and exocytosis in intact and permeabilized adrenal chromaffin cells: role of calcium and protein kinase C. Cell Signal (1989) 1.17

Soluble proteins as modulators of the exocytotic reaction of permeabilised rat mast cells. J Cell Sci (1989) 1.13

Dual role for guanine nucleotides in stimulus-secretion coupling. Fed Proc (1986) 1.12

GTP-binding proteins in the control of exocytosis. Cold Spring Harb Symp Quant Biol (1988) 1.08

Chemotactic factor-induced membrane potential changes in rabbit neutrophils monitored by the fluorescent dye 3,3'-dipropylthiadicarbocyanine iodide. Biochim Biophys Acta (1980) 1.07

Induction of exocytosis from permeabilized mast cells by the guanosine triphosphatases Rac and Cdc42. Mol Biol Cell (1998) 1.07

ATP inhibits onset of exocytosis in permeabilised mast cells. Biosci Rep (1989) 1.07

The caffeine-sensitive Ca2+ store in bovine adrenal chromaffin cells; an examination of its role in triggering secretion and Ca2+ homeostasis. FEBS Lett (1990) 1.06

Regulated exocytotic secretion from permeabilized cells. Methods Enzymol (1992) 1.03

Intracellular application of guanosine-5'-O-(3-thiotriphosphate) induces exocytotic granule fusion in guinea pig eosinophils. J Exp Med (1990) 1.03

Cytoplasmic free calcium measured by quin2 fluorescence in isolated ventricular myocytes at rest and during potassium-depolarization. Biochem Biophys Res Commun (1984) 1.02

Demonstration of an enzyme variant in a case of congenital methaemoglobinaemia. Br Med J (1967) 1.02

Effects of nicotinic acid on insulin sensitivity and blood pressure in healthy subjects. J Hum Hypertens (2000) 1.02

Rho guanine nucleotide dissociation inhibitor protein (RhoGDI) inhibits exocytosis in mast cells. EMBO J (1996) 1.01

Ecological effects of sewage discharge in the marine environment. Proc R Soc Lond B Biol Sci (1971) 1.01

The effect of mitogenic lectins and monoclonal antibodies on intracellular free calcium concentration in human T-lymphocytes. Biochem J (1984) 1.01

Inhibitory effects of natural flavonoids on secretion from mast cells and neutrophils. Arzneimittelforschung (1981) 1.00

Purification and identification of FOAD-II, a cytosolic protein that regulates secretion in streptolysin-O permeabilized mast cells, as a rac/rhoGDI complex. Mol Biol Cell (1996) 0.99

The dual effector system for exocytosis in mast cells: obligatory requirement for both Ca2+ and GTP. Biosci Rep (1987) 0.97

Degranulation of individual mast cells in response to Ca2+ and guanine nucleotides: an all-or-none event. J Cell Biol (1993) 0.97

Rat mast cells permeabilized with Sendai virus secrete histamine in response to Ca2+ buffered in the micromolar range. Biochem J (1983) 0.97

The relationship between mitogen-induced membrane potential changes and intracellular free calcium in human T-lymphocytes. Biochim Biophys Acta (1986) 0.94

Metabolic actions of growth hormone in man. Endocr J (1996) 0.94

Guanine nucleotide is essential and Ca2+ is a modulator in the exocytotic reaction of permeabilized rat mast cells. Biochem J (1992) 0.94

ATP-dependent and ATP-independent pathways of exocytosis revealed by interchanging glutamate and chloride as the major anion in permeabilized mast cells. Cell Regul (1990) 0.94

Plasma-membrane location of phosphatidylinositol hydrolysis in rabbit neutrophils stimulated with formylmethionyl-leucylphenylalanine. Biochem J (1982) 0.93

The effects of pertussis toxin on human T lymphocytes. Immunology (1988) 0.93

Size measurements on isolated rat heart cells using Coulter analysis and light scatter flow cytometry. Biochim Biophys Acta (1979) 0.91

Spatial localization of agonist-induced Ca2+ entry in bovine adrenal chromaffin cells. Different patterns induced by histamine and angiotensin II, and relationship to catecholamine release. J Cell Sci (1993) 0.91

Ultrastructural characterization of tannic acid-arrested degranulation of permeabilized guinea pig eosinophils stimulated with GTP-gamma-S. Eur J Cell Biol (1996) 0.90

Nucleotides and divalent cations as effectors and modulators of exocytosis in permeabilized rat mast cells. Philos Trans R Soc Lond B Biol Sci (1992) 0.88

Evidence for protein dephosphorylation as a permissive step in GTP-gamma-S-induced exocytosis from permeabilized mast cells. Cell Regul (1990) 0.86

Early events in the activation of Ca2+ dependent secretion: studies with rat peritoneal mast cells. J Physiol (Paris) (1980) 0.86

Non-T cell-mediated cytolysis of antibody-coated sheep red blood cells requires Mg++ but not Ca++: An argument against a conventional "stimulus-secretion" mechanism for cytolysis. J Immunol (1975) 0.85

Potentiation and inhibition of secretion from neutrophils by phorbol ester. FEBS Lett (1986) 0.85

A survey of GTP-binding proteins and other potential key regulators of exocytotic secretion in eosinophils. Apparent absence of rab3 and vesicle fusion protein homologues. J Cell Sci (1995) 0.85

Cytosol Mg2+ modulates Ca2+ ionophore induced secretion from rabbit neutrophils. FEBS Lett (1983) 0.85

Mechanisms of granule enzyme secretion from permeabilized guinea pig eosinophils. Dependence on Ca2+ and guanine nucleotides. J Immunol (1991) 0.84

Relationship between arachidonate generation and exocytosis in permeabilized mast cells. Biochem J (1990) 0.84

Adults with growth hormone deficiency have abnormal body composition but normal energy metabolism. J Clin Endocrinol Metab (1995) 0.84

Stimulation of exocytotic degranulation by microinjection of the ras oncogene protein into rat mast cells. Oncogene (1988) 0.83

Modulation of the exocytotic reaction of permeabilised rat mast cells by ATP, other nucleotides and Mg2+. Biochim Biophys Acta (1991) 0.83

Differential accumulation of catecholamines, proenkephalin- and chromogranin A-derived peptides in the medium after chronic nicotine stimulation of cultured bovine adrenal chromaffin cells. Peptides (1990) 0.83

Examination of the role of ADP-ribosylation factor and phospholipase D activation in regulated exocytosis in chromaffin and PC12 cells. J Neurochem (1998) 0.83

The relationship between anaphylactic histamine secretion and the permability of the mast cell membrane to calcium. Int Arch Allergy Appl Immunol (1975) 0.83

Effects of different oral oestrogen formulations on insulin-like growth factor-I, growth hormone and growth hormone binding protein in post-menopausal women. Clin Endocrinol (Oxf) (1993) 0.83

Evidence for functional expression of vascular angiotensin II type 2 receptors in patients with insulin resistance. Diabetes Obes Metab (2008) 0.82

Flow cytometric detection of membrane potential changes in murine lymphocytes induced by concanavalin A. Biochem J (1984) 0.82

Practical considerations regarding the use of streptolysin-O as a permeabilising agent for cells in the investigation of exocytosis. Biosci Rep (1996) 0.82

Kinetic characterization of guanine-nucleotide-induced exocytosis from permeabilized rat mast cells. Biochem J (1993) 0.82

Thirty years of stimulus-secretion coupling: from Ca(2+) toGTP in the regulation of exocytosis. Biochimie (2000) 0.81

Estrogen, lipid oxidation, and body fat. N Engl J Med (1995) 0.81

The role and mechanism of the GTP-binding protein GE in the control of regulated exocytosis. Biochem Soc Symp (1990) 0.81

Diagnosis of growth hormone deficiency in adults. Lancet (1994) 0.80

Late events in regulated exocytosis. Bioessays (1991) 0.80

A cell-physiological description of GE, a GTP-binding protein that mediates exocytosis. Ciba Found Symp (1993) 0.79

Ionophore monensin induces Na+-dependent secretion from rabbit neutrophils. requirement for intracellular Ca2+ stores. Biochim Biophys Acta (1983) 0.79

Rat mast cells degranulate in response to microinjection of guanine nucleotide. J Cell Sci (1991) 0.79

Phosphatidylinositol transfer proteins and protein kinase C make separate but non-interacting contributions to the phosphorylation state necessary for secretory competence in rat mast cells. Biochem J (2001) 0.79