PubRank

R N Bergman

Author PubWeight™ 197.79‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Quantitative estimation of insulin sensitivity. Am J Physiol 1979 7.37
2 Role of glucose and insulin resistance in development of type 2 diabetes mellitus: results of a 25-year follow-up study. Lancet 1992 6.28
3 Physiologic evaluation of factors controlling glucose tolerance in man: measurement of insulin sensitivity and beta-cell glucose sensitivity from the response to intravenous glucose. J Clin Invest 1981 5.82
4 Quantification of the relationship between insulin sensitivity and beta-cell function in human subjects. Evidence for a hyperbolic function. Diabetes 1993 5.70
5 Assessment of insulin sensitivity in vivo. Endocr Rev 1985 4.21
6 Mapping genes for NIDDM. Design of the Finland-United States Investigation of NIDDM Genetics (FUSION) Study. Diabetes Care 1998 3.99
7 MINMOD: a computer program to calculate insulin sensitivity and pancreatic responsivity from the frequently sampled intravenous glucose tolerance test. Comput Methods Programs Biomed 1986 3.54
8 Estimation of endogenous glucose production during hyperinsulinemic-euglycemic glucose clamps. Comparison of unlabeled and labeled exogenous glucose infusates. Diabetes 1987 2.95
9 Equivalence of the insulin sensitivity index in man derived by the minimal model method and the euglycemic glucose clamp. J Clin Invest 1987 2.81
10 Intensity and amount of physical activity in relation to insulin sensitivity: the Insulin Resistance Atherosclerosis Study. JAMA 1998 2.56
11 Insulin transport across capillaries is rate limiting for insulin action in dogs. J Clin Invest 1989 2.32
12 Dietary restriction increases insulin sensitivity and lowers blood glucose in rhesus monkeys. Am J Physiol 1994 2.13
13 Reduced sample number for calculation of insulin sensitivity and glucose effectiveness from the minimal model. Suitability for use in population studies. Diabetes 1993 2.03
14 Type 2 diabetes: evidence for linkage on chromosome 20 in 716 Finnish affected sib pairs. Proc Natl Acad Sci U S A 1999 1.91
15 Free fatty acid as a link in the regulation of hepatic glucose output by peripheral insulin. Diabetes 1995 1.91
16 Dietary restriction and glucose regulation in aging rhesus monkeys: a follow-up report at 8.5 yr. Am J Physiol Endocrinol Metab 2001 1.86
17 Familiality of quantitative metabolic traits in Finnish families with non-insulin-dependent diabetes mellitus. Finland-United States Investigation of NIDDM Genetics (FUSION) Study investigators. Hum Hered 1999 1.76
18 A comparison between the minimal model and the glucose clamp in the assessment of insulin sensitivity across the spectrum of glucose tolerance. Insulin Resistance Atherosclerosis Study. Diabetes 1994 1.73
19 Minimal model analysis of intravenous glucose tolerance test-derived insulin sensitivity in diabetic subjects. J Clin Endocrinol Metab 1990 1.71
20 Role of glucose effectiveness in the determination of glucose tolerance. Diabetes Care 1996 1.68
21 Quantitative estimation of beta cell sensitivity to glucose in the intact organism: a minimal model of insulin kinetics in the dog. Diabetes 1980 1.67
22 Saturable transport of insulin from plasma into the central nervous system of dogs in vivo. A mechanism for regulated insulin delivery to the brain. J Clin Invest 1993 1.67
23 Caloric restriction per se is a significant factor in improvements in glycemic control and insulin sensitivity during weight loss in obese NIDDM patients. Diabetes Care 1994 1.67
24 Longitudinal compensation for fat-induced insulin resistance includes reduced insulin clearance and enhanced beta-cell response. Diabetes 2000 1.63
25 Causal linkage between insulin suppression of lipolysis and suppression of liver glucose output in dogs. J Clin Invest 1996 1.60
26 Dietary fat and insulin sensitivity in a triethnic population: the role of obesity. The Insulin Resistance Atherosclerosis Study (IRAS) Am J Clin Nutr 1997 1.59
27 Diurnal variation in glucose tolerance. Cyclic suppression of insulin action and insulin secretion in normal-weight, but not obese, subjects. Diabetes 1992 1.56
28 Modified protocols improve insulin sensitivity estimation using the minimal model. Am J Physiol 1987 1.54
29 Prolonged elevation of plasma free fatty acids impairs pancreatic beta-cell function in obese nondiabetic humans but not in individuals with type 2 diabetes. Diabetes 2000 1.52
30 Insulin sensitivity and B-cell responsiveness to glucose during late pregnancy in lean and moderately obese women with normal glucose tolerance or mild gestational diabetes. Am J Obstet Gynecol 1990 1.48
31 Insulin resistance in short children with intrauterine growth retardation. J Clin Endocrinol Metab 1997 1.48
32 Insulin sensitivity index, acute insulin response, and glucose effectiveness in a population-based sample of 380 young healthy Caucasians. Analysis of the impact of gender, body fat, physical fitness, and life-style factors. J Clin Invest 1996 1.45
33 Pathogenesis of age-related glucose intolerance in man: insulin resistance and decreased beta-cell function. J Clin Endocrinol Metab 1985 1.43
34 Ethnic differences in carotid wall thickness. The Insulin Resistance Atherosclerosis Study. Stroke 1996 1.42
35 Insulin sensitivity and acute insulin response in African-Americans, non-Hispanic whites, and Hispanics with NIDDM: the Insulin Resistance Atherosclerosis Study. Diabetes 1997 1.42
36 Novel glucosensor for hypoglycemic detection localized to the portal vein. Diabetes 1997 1.36
37 The modified minimal model: application to measurement of insulin sensitivity in children. J Clin Endocrinol Metab 1990 1.35
38 Kinetics and specificity of insulin uptake from plasma into cerebrospinal fluid. Am J Physiol 1990 1.31
39 Acute enhancement of insulin secretion by FFA in humans is lost with prolonged FFA elevation. Am J Physiol 1999 1.30
40 The insulin sensitivity index in nondiabetic man. Correlation between clamp-derived and IVGTT-derived values. Diabetes 1986 1.30
41 Peripheral effects of insulin dominate suppression of fasting hepatic glucose production. Am J Physiol 1990 1.29
42 Modeling error and apparent isotope discrimination confound estimation of endogenous glucose production during euglycemic glucose clamps. Diabetes 1988 1.28
43 Insulin sensitivity from meal tolerance tests in normal subjects: a minimal model index. J Clin Endocrinol Metab 2000 1.25
44 Influence of total vs. visceral fat on insulin action and secretion in African American and white children. Obes Res 2001 1.25
45 Inhibition of lipolysis causes suppression of endogenous glucose production independent of changes in insulin. Am J Physiol Endocrinol Metab 2000 1.24
46 Indirect effect of insulin to suppress endogenous glucose production is dominant, even with hyperglucagonemia. J Clin Invest 1997 1.22
47 Transendothelial insulin transport is not saturable in vivo. No evidence for a receptor-mediated process. J Clin Invest 1996 1.21
48 Intraportal glucose infusion matched to oral glucose absorption. Lack of evidence for "gut factor" involvement in hepatic glucose storage. Diabetes 1982 1.20
49 Minimal modeling, partition analysis, and the estimation of insulin sensitivity. Fed Proc 1980 1.18
50 The peroxisome proliferator-activated receptor-gamma2 Pro12A1a variant: association with type 2 diabetes and trait differences. Diabetes 2001 1.17
51 Primacy of liver glucosensors in the sympathetic response to progressive hypoglycemia. Proc Natl Acad Sci U S A 1994 1.15
52 Dynamics of glucose autoregulation in the isolated, blood-perfused canine liver. Am J Physiol 1974 1.15
53 Glucose tolerance and insulin action in rats with renovascular hypertension. Hypertension 1991 1.15
54 Diminished insulin sensitivity and increased insulin response in nonobese, nondiabetic Mexican Americans. Metabolism 1990 1.14
55 Importance of hepatic glucoreceptors in sympathoadrenal response to hypoglycemia. Diabetes 1991 1.12
56 Integrated control of hepatic glucose metabolism. Fed Proc 1977 1.12
57 Evidence for entry of plasma insulin into cerebrospinal fluid through an intermediate compartment in dogs. Quantitative aspects and implications for transport. J Clin Invest 1991 1.12
58 The contribution of insulin-dependent and insulin-independent glucose uptake to intravenous glucose tolerance in healthy human subjects. Diabetes 1994 1.12
59 Pioglitazone increases insulin sensitivity, reduces blood glucose, insulin, and lipid levels, and lowers blood pressure, in obese, insulin-resistant rhesus monkeys. Diabetes 1994 1.12
60 Increased beta-cell secretory capacity as mechanism for islet adaptation to nicotinic acid-induced insulin resistance. Diabetes 1989 1.09
61 Portal vein afferents are critical for the sympathoadrenal response to hypoglycemia. Diabetes 2000 1.09
62 Importance of glucose per se to intravenous glucose tolerance. Comparison of the minimal-model prediction with direct measurements. Diabetes 1985 1.09
63 Optimal segments: a method for smoothing tracer data to calculate metabolic fluxes. Am J Physiol 1983 1.09
64 A genome-wide association scan for acute insulin response to glucose in Hispanic-Americans: the Insulin Resistance Atherosclerosis Family Study (IRAS FS). Diabetologia 2009 1.08
65 Dose-response relationship between lymph insulin and glucose uptake reveals enhanced insulin sensitivity of peripheral tissues. Diabetes 1992 1.08
66 Variation in the resistin gene is associated with obesity and insulin-related phenotypes in Finnish subjects. Diabetologia 2004 1.07
67 Synergistic effect of portal glucose and glucagon-like peptide-1 to lower systemic glucose and stimulate counter-regulatory hormones. Diabetologia 2005 1.07
68 Quantitative trait loci for abdominal fat and BMI in Hispanic-Americans and African-Americans: the IRAS Family study. Int J Obes (Lond) 2005 1.06
69 Angiotensin II induces insulin resistance independent of changes in interstitial insulin. Am J Physiol 1999 1.06
70 Critical evaluation of the combined model approach for estimation of prehepatic insulin secretion. Am J Physiol 1998 1.05
71 Importance of transcapillary insulin transport to dynamics of insulin action after intravenous glucose. Am J Physiol 1994 1.04
72 Carotid artery atherosclerosis in type-2 diabetic and nondiabetic subjects with and without symptomatic coronary artery disease (The Insulin Resistance Atherosclerosis Study). Am J Cardiol 2000 1.03
73 Low insulin sensitivity is associated with clustering of cardiovascular disease risk factors. Am J Epidemiol 1997 1.01
74 The pilot gland approach to the study of insulin secretory dynamics. Recent Prog Horm Res 1971 1.01
75 Candidate loci for insulin sensitivity and disposition index from a genome-wide association analysis of Hispanic participants in the Insulin Resistance Atherosclerosis (IRAS) Family Study. Diabetologia 2009 1.01
76 Relationship of insulin clearance and secretion to insulin sensitivity in non-diabetic Mexican Americans. Eur J Clin Invest 1992 1.01
77 Improvements in glucose homeostasis in response to regular exercise are influenced by the PPARG Pro12Ala variant: results from the HERITAGE Family Study. Diabetologia 2009 1.00
78 The role of liver glucosensors in the integrated sympathetic response induced by deep hypoglycemia in dogs. Diabetes 1994 1.00
79 Dynamics of glucose production and uptake are more closely related to insulin in hindlimb lymph than in thoracic duct lymph. Diabetes 1994 1.00
80 Linkage disequilibrium between microsatellite markers extends beyond 1 cM on chromosome 20 in Finns. Genome Res 2001 0.99
81 Genome-wide linkage scans for prediabetes phenotypes in response to 20 weeks of endurance exercise training in non-diabetic whites and blacks: the HERITAGE Family Study. Diabetologia 2005 0.99
82 Repeatability of insulin sensitivity and glucose effectiveness from the minimal model. Implications for study design. Diabetes 1994 0.97
83 Hypoglycemic detection does not occur in the hepatic artery or liver: findings consistent with a portal vein glucosensor locus. Diabetes 2001 0.96
84 Treatment with a somatostatin analog decreases pancreatic B-cell and whole body sensitivity to glucose. J Clin Endocrinol Metab 1990 0.96
85 Pathophysiology of malnutrition in the adult cancer patient. Cancer 1986 0.94
86 Method of insulin administration has no effect on insulin sensitivity estimates from the insulin-modified minimal model protocol. Diabetes 1997 0.93
87 Dynamics of hepatic and peripheral insulin effects suggest common rate-limiting step in vivo. Diabetes 1993 0.93
88 Interaction of insulin and glucose in the control of hepatic glucose balance. Am J Physiol 1974 0.93
89 Rapid oscillations in omental lipolysis are independent of changing insulin levels in vivo. J Clin Invest 2000 0.92
90 Differences between the tolbutamide-boosted and the insulin-modified minimal model protocols. Diabetes 1997 0.91
91 Effects of insulin-like growth factor I (IGF-I) therapy on body composition and insulin resistance in IGF-I gene deletion. J Clin Endocrinol Metab 2000 0.91
92 Quantitation of measurement error with Optimal Segments: basis for adaptive time course smoothing. Am J Physiol 1993 0.91
93 Putative hypothalamic glucoreceptors play no essential role in the response to moderate hypoglycemia. Diabetes 1986 0.91
94 Accurate measurement of endogenous insulin secretion does not require separate assessment of C-peptide kinetics. Diabetes 2000 0.91
95 Prehepatic beta-cell secretion during the intravenous glucose tolerance test in humans: application of a combined model of insulin and C-peptide kinetics. J Clin Endocrinol Metab 1989 0.91
96 Direct enhancement of insulin secretion by vagal stimulation of the isolated pancreas. Am J Physiol 1973 0.91
97 Synergism of glucose and fructose in net glycogen synthesis in perfused rat livers. J Biol Chem 1986 0.90
98 OOPSEG: a data smoothing program for quantitation and isolation of random measurement error. Comput Methods Programs Biomed 1995 0.90
99 Deterioration in carbohydrate metabolism and lipoprotein changes induced by modern, high fat diet in Pima Indians and Caucasians. J Clin Endocrinol Metab 1991 0.90
100 Familial resemblance for glucose and insulin metabolism indices derived from an intravenous glucose tolerance test in Blacks and Whites of the HERITAGE Family Study. Clin Genet 2001 0.90
101 The insulin sensitivity index. Correlation in dogs between values determined from the intravenous glucose tolerance test and the euglycemic glucose clamp. Diabetes 1984 0.89
102 Extrapancreatic effect of somatostatin infusion to increase glucose clearance. Am J Physiol 1984 0.89
103 Insulin secretion, obesity, and potential behavioral influences: results from the Insulin Resistance Atherosclerosis Study (IRAS). Diabetes Metab Res Rev 2001 0.89
104 Calculated pattern of intraportal insulin appearance without independent assessment of C-peptide kinetics. Diabetes 1987 0.88
105 Enhancement of hepatic glycogen by gluconeogenic precursors: substrate flux or metabolic control? Am J Physiol 1990 0.88
106 A minimal-model-based glucose clamp yielding insulin sensitivity independent of glycemia. Diabetes 1982 0.88
107 Neurohypophyseal hormone-responsive renal adenylate cyclase. IV. A random-hit matrix model for coupline in a hormone-sensitive adenylate cyclase system. J Biol Chem 1978 0.87
108 Simulation study of control of hepatic glycogen synthesis by glucose and insulin. Am J Physiol 1976 0.87
109 Defects in carbohydrate metabolism in oral contraceptive users without apparent metabolic risk factors. J Clin Endocrinol Metab 1994 0.87
110 Glucose effectiveness assessed under dynamic and steady state conditions. Comparability of uptake versus production components. J Clin Invest 1997 0.87
111 Reassessment of glucose effectiveness and insulin sensitivity from minimal model analysis: a theoretical evaluation of the single-compartment glucose distribution assumption. Diabetes 1997 0.87
112 Short-term hyperglycemia and hyperinsulinemia improve insulin action but do not alter glucose action in normal humans. Am J Physiol 1992 0.86
113 Mechanism of protracted metabolic effects of fatty acid acylated insulin, NN304, in dogs: retention of NN304 by albumin. Diabetologia 1999 0.86
114 Improved estimation of anaplerosis in heart using 13C NMR. Am J Physiol 1997 0.85
115 Validation of methods for measurement of insulin secretion in humans in vivo. Diabetes 2000 0.85
116 Fructose effect to suppress hepatic glycogen degradation. J Biol Chem 1987 0.85
117 Insulin resistance and beta-cell dysfunction in aging: the importance of dietary carbohydrate. J Clin Endocrinol Metab 1988 0.84
118 Determination of portal insulin absorption from peritoneum via novel nonisotopic method. Diabetes 1990 0.84
119 Proinsulin and insulin concentrations in relation to carotid wall thickness: Insulin Resistance Atherosclerosis Study. Stroke 1998 0.84
120 Defects in beta-cell function and insulin sensitivity in normoglycemic streptozocin-treated baboons: a model of preclinical insulin-dependent diabetes. J Clin Endocrinol Metab 1988 0.84
121 Macrophage gene expression in adipose tissue is associated with insulin sensitivity and serum lipid levels independent of obesity. Obesity (Silver Spring) 2013 0.84
122 The multiphasic profile of free fatty acids during the intravenous glucose tolerance test is unresponsive to exogenous insulin. Metabolism 2004 0.84
123 Biphasic insulin secretion during intravenous glucose tolerance test promotes optimal interstitial insulin profile. Diabetes 1998 0.84
124 Role of portal insulin delivery in the disappearance of intravenous glucose and assessment of insulin sensitivity. Diabetes 1998 0.83
125 Response to deep hypoglycemia does not involve glucoreceptors in carotid perfused tissue. Am J Physiol 1988 0.83
126 Oscillations enhance the efficiency and stability of glucose disposal. Am J Physiol 1986 0.83
127 Search for the hypoglycemia receptor using the local irrigation approach. Adv Exp Med Biol 1991 0.81
128 Thoracic duct lymph. Relative contribution from splanchnic and muscle tissue. Diabetes 1993 0.81
129 Insulin sensitivity, insulin secretion and glucose effectiveness in diabetic and non-diabetic cirrhotic patients. Diabetologia 1993 0.80
130 Fluctuations of plasma glucose and insulin in conscious dogs receiving glucose infusions. Am J Physiol 1974 0.80
131 The influence of luteinizing hormone and insulin on sex steroids and sex hormone-binding globulin in the polycystic ovarian syndrome. Fertil Steril 1993 0.80
132 Beta-cell function and insulin sensitivity in nondiabetic HLA-identical siblings of insulin-dependent diabetics. Diabetes 1987 0.80
133 Lack of hepatic "interregulation" during inhibition of glycogenolysis in a canine model. Am J Physiol Endocrinol Metab 2001 0.80
134 Cause of glucose oscillations during glucose infusion: periodic variation in glucose uptake. Am J Physiol 1980 0.80
135 Insulin sensitivity accounts for glucose and lactate kinetics after intravenous glucose injection. Diabetes 1995 0.79
136 Studies of reproductive competence in male Dirofilaria immitis treated with milbemycin oxime. Trop Med Parasitol 1995 0.79
137 The W64R variant of the beta3-adrenergic receptor is not associated with type II diabetes or obesity in a large Finnish sample. Diabetologia 1999 0.79
138 Patterns of glycogen turnover in liver characterized by computer modeling. Am J Physiol 1987 0.79
139 PACBERG: an adaptive program for controlling the blood sugar. Comput Programs Biomed 1983 0.79
140 Biomarker models as surrogates for the disposition index in the Insulin Resistance Atherosclerosis Study. Diabet Med 2012 0.79
141 Recombinant deoxyribonucleic acid-derived 22K- and 20K-human growth hormone generate equivalent diabetogenic effects during chronic infusion in dogs. Endocrinology 1987 0.78
142 Effects of epinephrine on insulin secretion and action in humans. Interaction with aging. Diabetes 1993 0.78
143 Extracellular glucose distribution is not altered by insulin: analysis of plasma and interstitial L-glucose kinetics. Am J Physiol 1996 0.78
144 Evidence for direct action of alloxan to induce insulin resistance at the cellular level. Diabetologia 1998 0.78
145 Restoration of stable metabolic conditions during islet suppression in dogs. Am J Physiol 1992 0.77
146 Failure of acute hyperinsulinemia to alter blood pressure is not due to baroreceptor feedback. Am J Hypertens 1999 0.77
147 Conversion of oral glucose to lactate in dogs. Primary site and relative contribution to blood lactate. Diabetes 1991 0.77
148 Hepatic glucagon sensitivity and fasting glucose concentration in normal dogs. Am J Physiol 1992 0.77
149 Glucagon-stimulated glycogenolysis: time-dependent sensitivity to insulin. Am J Physiol 1979 0.76
150 Insulin sensitivity in the intact organism. Baillieres Clin Endocrinol Metab 1987 0.76
151 Intravenous insulin infusion to simulate subcutaneous absorption. Bioavailability and metabolic sequelae. Diabetes Care 1991 0.76
152 Glucose phosphorylation is not rate limiting for accumulation of glycogen from glucose in perfused livers from fasted rats. J Biol Chem 1989 0.76
153 Impact of computer simulation on diabetes research and practice. Diabetes Care 1990 0.75
154 Insulin action and metabolism in patients with head and neck cancer. Cancer 1991 0.75
155 Effect of insulin, glucose, and 2-deoxy-glucose infusion into the third cerebral ventricle of conscious dogs on plasma insulin, glucose, and free fatty acids. Diabetes 1980 0.75
156 Estimation of TCA cycle flux, aminotransferase flux, and anaplerosis in heart: validation with syntactic model. Am J Physiol 1995 0.75
157 [Role of the liver as a glucose sensor in the integrated response to hypoglycemia]. Journ Annu Diabetol Hotel Dieu 1996 0.75
158 SYNTAX: a rule-based stochastic simulation of the time-varying concentrations of positional isotopomers of metabolic intermediates. Comput Biomed Res 1994 0.75
159 Hypertension and insulin resistance: role of sympathetic nervous system activity. Am J Physiol 1992 0.75
160 BASREP: a method for maintaining euglycemia during somatostatin suppression of pancreatic secretion. Comput Methods Programs Biomed 1992 0.75
161 Paradoxical effect of troglitazone in normal animals: enhancement of adipocyte but reduction of liver insulin sensitivity. Diabetes 2000 0.75
162 Insulin and insulin-like growth factor-I responsiveness in polycystic ovarian syndrome. Fertil Steril 1992 0.75
163 Prediction of positional isotopomers of the citric acid cycle: the syntactic approach. Am J Physiol 1994 0.75
164 Diminished in vitro responsiveness of circulating erythroid progenitor cells to insulin as an indicator of insulin resistance. J Clin Endocrinol Metab 1985 0.75
165 Measurement error inherent in the determination of hepatic glucose balance. J Appl Physiol 1974 0.75
166 Dynamic control of hepatic glucose metabolism: Studies by experiment and computer simulation. Ann Biomed Eng 1975 0.75
167 Caval occlusion technique for hepatic venous sampling: a new approach to estimating splanchnic substrate balance in conscious dogs. Metabolism 1979 0.75
168 Cardiac toxicity associated with acute maprotiline self-poisoning. Am J Emerg Med 1984 0.75
169 OPSEG: a general routine for smoothing and interpolating discrete biological data. Comput Methods Programs Biomed 1988 0.75