Published in Cell on May 28, 1999
The ESCRT complexes: structure and mechanism of a membrane-trafficking network. Annu Rev Biophys Biomol Struct (2006) 5.21
Vps27 recruits ESCRT machinery to endosomes during MVB sorting. J Cell Biol (2003) 3.68
Role of Drosophila Rab5 during endosomal trafficking at the synapse and evoked neurotransmitter release. J Cell Biol (2003) 3.26
Phosphoinositides: tiny lipids with giant impact on cell regulation. Physiol Rev (2013) 3.21
Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain. EMBO J (2000) 2.49
PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody. Nat Cell Biol (2010) 2.33
Trafficking of phosphatidylinositol 3-phosphate from the trans-Golgi network to the lumen of the central vacuole in plant cells. Plant Cell (2001) 2.28
The ESCRT complexes. Crit Rev Biochem Mol Biol (2010) 2.23
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Translation of the phosphoinositide code by PI effectors. Nat Chem Biol (2010) 1.86
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Pleckstrin homology (PH) domains and phosphoinositides. Biochem Soc Symp (2007) 1.74
Treble clef finger--a functionally diverse zinc-binding structural motif. Nucleic Acids Res (2001) 1.71
Biogenesis of the protein storage vacuole crystalloid. J Cell Biol (2000) 1.67
Membrane binding domains. Biochim Biophys Acta (2006) 1.67
Cellular functions of phosphatidylinositol 3-phosphate and FYVE domain proteins. Biochem J (2001) 1.62
PtdIns4P recognition by Vps74/GOLPH3 links PtdIns 4-kinase signaling to retrograde Golgi trafficking. J Cell Biol (2009) 1.58
Histone H3K4me3 binding is required for the DNA repair and apoptotic activities of ING1 tumor suppressor. J Mol Biol (2008) 1.57
Conditional peripheral membrane proteins: facing up to limited specificity. Structure (2011) 1.55
Endosomal localization and receptor dynamics determine tyrosine phosphorylation of hepatocyte growth factor-regulated tyrosine kinase substrate. Mol Cell Biol (2000) 1.49
Targeting of the FYVE domain to endosomal membranes is regulated by a histidine switch. Proc Natl Acad Sci U S A (2005) 1.47
Negative regulation of PI 3-kinase by Ruk, a novel adaptor protein. EMBO J (2000) 1.41
Phosphatidylinositol 3-phosphate recognition and membrane docking by the FYVE domain. Biochim Biophys Acta (2006) 1.37
The Vps27/Hse1 complex is a GAT domain-based scaffold for ubiquitin-dependent sorting. Dev Cell (2007) 1.36
A FYVE-finger-containing protein, Rabip4, is a Rab4 effector involved in early endosomal traffic. Proc Natl Acad Sci U S A (2001) 1.35
Structural determinants of Ras-Raf interaction analyzed in live cells. Mol Biol Cell (2002) 1.31
The Phox homology (PX) domain, a new player in phosphoinositide signalling. Biochem J (2001) 1.31
Aczonin, a 550-kD putative scaffolding protein of presynaptic active zones, shares homology regions with Rim and Bassoon and binds profilin. J Cell Biol (1999) 1.31
Acquisition of Hrs, an essential component of phagosomal maturation, is impaired by mycobacteria. Mol Cell Biol (2004) 1.20
The ESCRT machinery: from the plasma membrane to endosomes and back again. Crit Rev Biochem Mol Biol (2014) 1.12
Structural insight into histone recognition by the ING PHD fingers. Curr Drug Targets (2009) 1.11
Pathogen destruction versus intracellular survival: the role of lipids as phagosomal fate determinants. J Clin Invest (2008) 1.10
Characterization of a novel phosphatidylinositol 3-phosphate-binding protein containing two FYVE fingers in tandem that is targeted to the Golgi. Biochem J (2001) 1.09
A key claudin extracellular loop domain is critical for epithelial barrier integrity. Am J Pathol (2008) 1.09
A multi-colour/multi-affinity marker set to visualize phosphoinositide dynamics in Arabidopsis. Plant J (2013) 1.07
Molecular and structural basis of ESCRT-III recruitment to membranes during archaeal cell division. Mol Cell (2011) 1.03
Mechanistic similarities in docking of the FYVE and PX domains to phosphatidylinositol 3-phosphate containing membranes. Prog Lipid Res (2007) 1.02
Membrane insertion of the FYVE domain is modulated by pH. Proteins (2009) 1.01
Capturing spontaneous partitioning of peripheral proteins using a biphasic membrane-mimetic model. J Phys Chem B (2011) 0.95
Investigation of the binding geometry of a peripheral membrane protein. Biochemistry (2005) 0.90
Cellular and molecular interactions of phosphoinositides and peripheral proteins. Chem Phys Lipids (2014) 0.89
Vesicle formation within endosomes: An ESCRT marks the spot. Commun Integr Biol (2012) 0.88
FYVE zinc-finger proteins in the plant model Arabidopsis thaliana: identification of PtdIns3P-binding residues by comparison of classic and variant FYVE domains. Biochem J (2001) 0.88
Oligomerization of ZFYVE27 (Protrudin) is necessary to promote neurite extension. PLoS One (2011) 0.87
Structures of three members of Pfam PF02663 (FmdE) implicated in microbial methanogenesis reveal a conserved α+β core domain and an auxiliary C-terminal treble-clef zinc finger. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 0.86
Defective Hyphal induction of a Candida albicans phosphatidylinositol 3-phosphate 5-kinase null mutant on solid media does not lead to decreased virulence. Infect Immun (2002) 0.82
Phosphoinositides differentially regulate protrudin localization through the FYVE domain. J Biol Chem (2012) 0.82
A high-resolution solution structure of a trypanosomatid FYVE domain. Protein Sci (2007) 0.81
Discovery of novel membrane binding structures and functions. Biochem Cell Biol (2014) 0.80
Molecular analysis of protein-phosphoinositide interactions. Curr Top Microbiol Immunol (2012) 0.80
The N-terminal cysteine cluster is essential for membrane targeting of B/K protein. Biochem J (2001) 0.79
Identification and structural characterization of FYVE domain-containing proteins of Arabidopsis thaliana. BMC Plant Biol (2010) 0.78
Binding to any ESCRT can mediate ubiquitin-independent cargo sorting. Traffic (2013) 0.78
Structural basis for PI(4)P-specific membrane recruitment of the Legionella pneumophila effector DrrA/SidM. Structure (2014) 0.78
Membrane targeting of the Spir·formin actin nucleator complex requires a sequential handshake of polar interactions. J Biol Chem (2015) 0.77
FYVE1/FREE1 Interacts with the PYL4 ABA Receptor and Mediates its Delivery to the Vacuolar Degradation Pathway. Plant Cell (2016) 0.77
Sequence-specific 1H, 15N and 13C resonance assignments of the EEA1 FYVE domain. J Biomol NMR (2000) 0.76
Receptor-mediated Endocytosis 8 Utilizes an N-terminal Phosphoinositide-binding Motif to Regulate Endosomal Clathrin Dynamics. J Biol Chem (2015) 0.76
A window into domain amplification through Piccolo in teleost fish. G3 (Bethesda) (2012) 0.76
CFLAP1 and CFLAP2 Are Two bHLH Transcription Factors Participating in Synergistic Regulation of AtCFL1-Mediated Cuticle Development in Arabidopsis. PLoS Genet (2016) 0.76
Time-resolved ultrastructural detection of phosphatidylinositol 3-phosphate. J Histochem Cytochem (2010) 0.76
Disruption of the plant-specific CFS1 gene impairs autophagosome turnover and triggers EDS1-dependent cell death. Sci Rep (2017) 0.75
The zinc finger domain of RING finger protein 141 reveals a unique RING fold. Protein Sci (2017) 0.75
Structure and lipid transport mechanism of a StAR-related domain. Nat Struct Biol (2000) 3.65
Crystal structure of the cys2 activator-binding domain of protein kinase C delta in complex with phorbol ester. Cell (1995) 3.08
Structure of the adenylyl cyclase catalytic core. Nature (1997) 2.81
Structure of the GAF domain, a ubiquitous signaling motif and a new class of cyclic GMP receptor. EMBO J (2000) 2.64
Catalytic mechanism of the adenylyl and guanylyl cyclases: modeling and mutational analysis. Proc Natl Acad Sci U S A (1997) 2.01
Structure of type IIbeta phosphatidylinositol phosphate kinase: a protein kinase fold flattened for interfacial phosphorylation. Cell (1998) 1.87
Two amino acid substitutions convert a guanylyl cyclase, RetGC-1, into an adenylyl cyclase. Proc Natl Acad Sci U S A (1998) 1.69
Specificity determinants in phosphoinositide dephosphorylation: crystal structure of an archetypal inositol polyphosphate 5-phosphatase. Cell (2001) 1.60
The activation loop of phosphatidylinositol phosphate kinases determines signaling specificity. Mol Cell (2000) 1.34
Catalytic mechanism and regulation of mammalian adenylyl cyclases. Mol Pharmacol (1998) 1.30
Hydrophobic core repacking and aromatic-aromatic interaction in the thermostable mutant of T4 lysozyme Ser 117-->Phe. Protein Sci (1993) 1.22
Recognizing phosphatidylinositol 3-phosphate. Cell (2001) 1.18
The human mu opioid receptor: modulation of functional desensitization by calcium/calmodulin-dependent protein kinase and protein kinase C. J Neurosci (1995) 1.17
C2 domain conformational changes in phospholipase C-delta 1. Nat Struct Biol (1996) 1.12
Solvent structure in crystals of trypsin determined by X-ray and neutron diffraction. Proteins (1992) 1.06
Structure of the VHS domain of human Tom1 (target of myb 1): insights into interactions with proteins and membranes. Biochemistry (2000) 1.02
Coexpression of cloned alpha(1B), beta(2a), and alpha(2)/delta subunits produces non-inactivating calcium currents similar to those found in bovine chromaffin cells. J Neurosci (2000) 1.00
Second-site suppression of regulatory phosphorylation in Escherichia coli isocitrate dehydrogenase. Protein Sci (1996) 0.94
The flattened face of type II beta phosphatidylinositol phosphate kinase binds acidic phospholipid membranes. Biochemistry (1999) 0.93
Catalysis by phospholipase C delta1 requires that Ca2+ bind to the catalytic domain, but not the C2 domain. Biochemistry (1998) 0.89
Characterization and crystallization of a minimal catalytic core domain from mammalian type II adenylyl cyclase. Protein Sci (1997) 0.88
Three discrete regions of mammalian adenylyl cyclase form a site for Gsalpha activation. J Biol Chem (1997) 0.84
Similarity between C2 domain jaws and immunoglobulin CDRs. Nat Struct Biol (1997) 0.83
Intraoperative use of the mobile gamma camera in localizing and excising osteoid osteomas of the spine. Spine (Phila Pa 1976) (1993) 0.83
The variability of response of scoliotic spines to segmental spinal instrumentation. Spine (Phila Pa 1976) (1992) 0.83
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Altered responses to potassium in cerebellar neurons from weaver heterozygote mice. Exp Brain Res (1998) 0.79
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