Published in Commun Integr Biol on January 01, 2012
Molecular mechanisms of the membrane sculpting ESCRT pathway. Cold Spring Harb Perspect Biol (2013) 1.58
MicroRNAs transported by exosomes in body fluids as mediators of intercellular communication in cancer. Onco Targets Ther (2014) 1.22
Endosomal sorting complex required for transport (ESCRT) complexes induce phase-separated microdomains in supported lipid bilayers. J Biol Chem (2012) 0.91
Signaling by exosomal microRNAs in cancer. J Exp Clin Cancer Res (2015) 0.90
The endolysosomal system in cell death and survival. Cold Spring Harb Perspect Biol (2013) 0.85
Exosomes: Fundamental Biology and Roles in Cardiovascular Physiology. Annu Rev Physiol (2015) 0.80
Worming our way in and out of the Caenorhabditis elegans germline and developing embryo. Traffic (2013) 0.80
Hrs and STAM function synergistically to bind ubiquitin-modified cargoes in vitro. Biophys J (2015) 0.76
Bud-neck scaffolding as a possible driving force in ESCRT-induced membrane budding. Biophys J (2015) 0.76
Tumor susceptibility gene 101, TSG101, REGULATES predisposition towards apoptosis VIA ESCRT machinery accessory Proteins. Mol Biol Cell (2017) 0.75
BAR domains as sensors of membrane curvature: the amphiphysin BAR structure. Science (2003) 12.60
Tsg101 and the vacuolar protein sorting pathway are essential for HIV-1 budding. Cell (2001) 12.00
Membrane curvature and mechanisms of dynamic cell membrane remodelling. Nature (2005) 10.04
Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I. Cell (2001) 9.08
The Vps4p AAA ATPase regulates membrane association of a Vps protein complex required for normal endosome function. EMBO J (1998) 7.68
Escrt-III: an endosome-associated heterooligomeric protein complex required for mvb sorting. Dev Cell (2002) 7.32
The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins. Nature (2009) 6.99
Protein regulation by monoubiquitin. Nat Rev Mol Cell Biol (2001) 6.96
A single motif responsible for ubiquitin recognition and monoubiquitination in endocytic proteins. Nature (2002) 6.22
Parallels between cytokinesis and retroviral budding: a role for the ESCRT machinery. Science (2007) 6.13
The emerging shape of the ESCRT machinery. Nat Rev Mol Cell Biol (2007) 6.05
Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomes. Nat Cell Biol (2002) 5.83
The ESCRT complexes: structure and mechanism of a membrane-trafficking network. Annu Rev Biophys Biomol Struct (2006) 5.21
Endosome-associated complex, ESCRT-II, recruits transport machinery for protein sorting at the multivesicular body. Dev Cell (2002) 4.94
Plasma membrane deformation by circular arrays of ESCRT-III protein filaments. J Cell Biol (2008) 4.66
Membrane scission by the ESCRT-III complex. Nature (2009) 4.66
The ESCRT pathway. Dev Cell (2011) 4.47
Influenza virus M2 protein mediates ESCRT-independent membrane scission. Cell (2010) 4.33
Membrane budding and scission by the ESCRT machinery: it's all in the neck. Nat Rev Mol Cell Biol (2010) 4.29
Cortical constriction during abscission involves helices of ESCRT-III-dependent filaments. Science (2011) 4.26
Biogenesis and function of multivesicular bodies. Annu Rev Cell Dev Biol (2007) 4.08
Membrane curvature, lipid segregation, and structural transitions for phospholipids under dual-solvent stress. Biochemistry (1990) 4.06
Molecular mechanism of multivesicular body biogenesis by ESCRT complexes. Nature (2010) 4.05
Epsins and Vps27p/Hrs contain ubiquitin-binding domains that function in receptor endocytosis. Nat Cell Biol (2002) 3.94
ESCRT complexes and the biogenesis of multivesicular bodies. Curr Opin Cell Biol (2008) 3.90
Hrs regulates endosome membrane invagination and tyrosine kinase receptor signaling in Drosophila. Cell (2002) 3.72
Vps27 recruits ESCRT machinery to endosomes during MVB sorting. J Cell Biol (2003) 3.68
The Vps27p Hse1p complex binds ubiquitin and mediates endosomal protein sorting. Nat Cell Biol (2002) 3.62
Functional reconstitution of ESCRT-III assembly and disassembly. Cell (2009) 3.52
Helical structures of ESCRT-III are disassembled by VPS4. Science (2008) 3.38
Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes. J Cell Biol (2003) 3.07
Architectural and mechanistic insights into an EHD ATPase involved in membrane remodelling. Nature (2007) 2.96
ESCRT-II, an endosome-associated complex required for protein sorting: crystal structure and interactions with ESCRT-III and membranes. Dev Cell (2004) 2.86
Hrs recruits clathrin to early endosomes. EMBO J (2001) 2.82
Ordered assembly of the ESCRT-III complex on endosomes is required to sequester cargo during MVB formation. Dev Cell (2008) 2.74
Ubiquitin interactions of NZF zinc fingers. EMBO J (2004) 2.72
Release of autoinhibition converts ESCRT-III components into potent inhibitors of HIV-1 budding. Proc Natl Acad Sci U S A (2006) 2.63
Structural and mechanistic studies of VPS4 proteins. EMBO J (2005) 2.58
FYVE and coiled-coil domains determine the specific localisation of Hrs to early endosomes. J Cell Sci (2001) 2.48
Structure and functional interactions of the Tsg101 UEV domain. EMBO J (2002) 2.40
Endocytosis: the DUB version. Trends Cell Biol (2006) 2.39
Structural basis for endosomal targeting by the Bro1 domain. Dev Cell (2005) 2.28
The ESCRT complexes. Crit Rev Biochem Mol Biol (2010) 2.23
Molecular architecture and functional model of the complete yeast ESCRT-I heterotetramer. Cell (2007) 2.21
Recycling of ESCRTs by the AAA-ATPase Vps4 is regulated by a conserved VSL region in Vta1. J Cell Biol (2006) 2.18
Identification of human MVB12 proteins as ESCRT-I subunits that function in HIV budding. Cell Host Microbe (2007) 2.18
bicoid RNA localization requires specific binding of an endosomal sorting complex. Nature (2007) 2.11
Human ESCRT-II complex and its role in human immunodeficiency virus type 1 release. J Virol (2006) 2.06
Structure and disassembly of filaments formed by the ESCRT-III subunit Vps24. Structure (2008) 1.95
Host factors involved in retroviral budding and release. Nat Rev Microbiol (2011) 1.94
Mechanisms of EHD/RME-1 protein function in endocytic transport. Traffic (2008) 1.94
Crystal structure of a phosphatidylinositol 3-phosphate-specific membrane-targeting motif, the FYVE domain of Vps27p. Cell (1999) 1.92
ESCRT-III family members stimulate Vps4 ATPase activity directly or via Vta1. Dev Cell (2008) 1.91
Conserved functions of membrane active GTPases in coated vesicle formation. Science (2009) 1.90
Evolution of the multivesicular body ESCRT machinery; retention across the eukaryotic lineage. Traffic (2008) 1.86
Structure of the ESCRT-II endosomal trafficking complex. Nature (2004) 1.80
Computational model of membrane fission catalyzed by ESCRT-III. PLoS Comput Biol (2009) 1.78
Phosphatidylinositol 3-phosphate induces the membrane penetration of the FYVE domains of Vps27p and Hrs. J Biol Chem (2002) 1.74
Cell cycle-dependent subcellular localization of the TSG101 protein and mitotic and nuclear abnormalities associated with TSG101 deficiency. Proc Natl Acad Sci U S A (1998) 1.70
Eap45 in mammalian ESCRT-II binds ubiquitin via a phosphoinositide-interacting GLUE domain. J Biol Chem (2005) 1.68
Structural insight into the ESCRT-I/-II link and its role in MVB trafficking. EMBO J (2007) 1.60
Crystal structure of the VHS and FYVE tandem domains of Hrs, a protein involved in membrane trafficking and signal transduction. Cell (2000) 1.59
Structural and functional organization of the ESCRT-I trafficking complex. Cell (2006) 1.51
Interactions of TOM1L1 with the multivesicular body sorting machinery. J Biol Chem (2004) 1.44
Assembly of the AAA ATPase Vps4 on ESCRT-III. Mol Biol Cell (2010) 1.43
A novel requirement for C. elegans Alix/ALX-1 in RME-1-mediated membrane transport. Curr Biol (2007) 1.43
Comparative analysis of ESCRT-I, ESCRT-II and ESCRT-III function in Drosophila by efficient isolation of ESCRT mutants. J Cell Sci (2009) 1.42
Integrated structural model and membrane targeting mechanism of the human ESCRT-II complex. Dev Cell (2008) 1.40
The ESCRT machinery: new functions in viral and cellular biology. Biochem Soc Trans (2009) 1.40
Tom1, a VHS domain-containing protein, interacts with tollip, ubiquitin, and clathrin. J Biol Chem (2003) 1.37
Cryo-EM structure of dodecameric Vps4p and its 2:1 complex with Vta1p. J Mol Biol (2008) 1.33
Regulators of Vps4 ATPase activity at endosomes differentially influence the size and rate of formation of intralumenal vesicles. Mol Biol Cell (2010) 1.32
MVB-12, a fourth subunit of metazoan ESCRT-I, functions in receptor downregulation. PLoS One (2007) 1.29
Curvature and bending constants for phosphatidylserine-containing membranes. Biophys J (2003) 1.24
Hybrid structural model of the complete human ESCRT-0 complex. Structure (2009) 1.23
Ancient ESCRTs and the evolution of binary fission. Trends Microbiol (2009) 1.20
UBAP1 is a component of an endosome-specific ESCRT-I complex that is essential for MVB sorting. Curr Biol (2011) 1.19
Association of the endosomal sorting complex ESCRT-II with the Vps20 subunit of ESCRT-III generates a curvature-sensitive complex capable of nucleating ESCRT-III filaments. J Biol Chem (2011) 1.18
Modeling membrane deformations and lipid demixing upon protein-membrane interaction: the BAR dimer adsorption. Biophys J (2009) 1.17
Charged multivesicular body protein 2B (CHMP2B) of the endosomal sorting complex required for transport-III (ESCRT-III) polymerizes into helical structures deforming the plasma membrane. J Biol Chem (2011) 1.09
Activation of human VPS4A by ESCRT-III proteins reveals ability of substrates to relieve enzyme autoinhibition. J Biol Chem (2010) 1.08
ESCRT & Co. Biol Cell (2010) 1.06
Structural role of the Vps4-Vta1 interface in ESCRT-III recycling. Structure (2010) 1.03
ESCRT-0 assembles as a heterotetrameric complex on membranes and binds multiple ubiquitinylated cargoes simultaneously. J Biol Chem (2010) 1.01
The endosome-associated protein Hrs is hexameric and controls cargo sorting as a "master molecule". Structure (2006) 1.00
Dictyostelium Tom1 participates to an ancestral ESCRT-0 complex. Traffic (2008) 0.92
Ubiquitin binding in endocytosis--how tight should it be and where does it happen? Traffic (2006) 0.86
Division of labour in ESCRT complexes. Nat Cell Biol (2010) 0.83
Endofin recruits clathrin to early endosomes via TOM1. J Cell Sci (2005) 0.80
Katanin controls mitotic and meiotic spindle length. J Cell Biol (2006) 3.09
Genome-wide analysis of membrane targeting by S. cerevisiae pleckstrin homology domains. Mol Cell (2004) 2.83
A high-resolution C. elegans essential gene network based on phenotypic profiling of a complex tissue. Cell (2011) 2.64
Bro1 is an endosome-associated protein that functions in the MVB pathway in Saccharomyces cerevisiae. J Cell Sci (2003) 2.57
The yeast synaptojanin-like proteins control the cellular distribution of phosphatidylinositol (4,5)-bisphosphate. Mol Biol Cell (2002) 2.39
TFG-1 function in protein secretion and oncogenesis. Nat Cell Biol (2011) 2.13
A microtubule-independent role for centrosomes and aurora a in nuclear envelope breakdown. Dev Cell (2007) 1.81
The phosphatidylinositol 4,5-biphosphate and TORC2 binding proteins Slm1 and Slm2 function in sphingolipid regulation. Mol Cell Biol (2006) 1.79
Synthetic genetic array analysis of the PtdIns 4-kinase Pik1p identifies components in a Golgi-specific Ypt31/rab-GTPase signaling pathway. Mol Biol Cell (2004) 1.76
Multivesicular body sorting: ubiquitin ligase Rsp5 is required for the modification and sorting of carboxypeptidase S. Mol Biol Cell (2003) 1.72
UNC-6 (netrin) orients the invasive membrane of the anchor cell in C. elegans. Nat Cell Biol (2008) 1.61
Dynamic regulation of caveolin-1 trafficking in the germ line and embryo of Caenorhabditis elegans. Mol Biol Cell (2006) 1.58
UNC-45 is required for NMY-2 contractile function in early embryonic polarity establishment and germline cellularization in C. elegans. Dev Biol (2007) 1.44
EHBP-1 functions with RAB-10 during endocytic recycling in Caenorhabditis elegans. Mol Biol Cell (2010) 1.38
Assembly of the PtdIns 4-kinase Stt4 complex at the plasma membrane requires Ypp1 and Efr3. J Cell Biol (2008) 1.33
The phosphoinositide phosphatase Sjl2 is recruited to cortical actin patches in the control of vesicle formation and fission during endocytosis. Mol Cell Biol (2005) 1.22
Expression and imaging of fluorescent proteins in the C. elegans gonad and early embryo. Methods Cell Biol (2008) 1.22
Up-regulation of the mitotic checkpoint component Mad1 causes chromosomal instability and resistance to microtubule poisons. Proc Natl Acad Sci U S A (2012) 1.19
Cytoplasmic inositol hexakisphosphate production is sufficient for mediating the Gle1-mRNA export pathway. J Biol Chem (2004) 1.18
Association of the endosomal sorting complex ESCRT-II with the Vps20 subunit of ESCRT-III generates a curvature-sensitive complex capable of nucleating ESCRT-III filaments. J Biol Chem (2011) 1.18
The Saccharomyces cerevisiae LSB6 gene encodes phosphatidylinositol 4-kinase activity. J Biol Chem (2002) 1.13
The ESCRT machinery: from the plasma membrane to endosomes and back again. Crit Rev Biochem Mol Biol (2014) 1.12
ESCRT-0 assembles as a heterotetrameric complex on membranes and binds multiple ubiquitinylated cargoes simultaneously. J Biol Chem (2010) 1.01
Palmitoylation controls the dynamics of budding-yeast heterochromatin via the telomere-binding protein Rif1. Proc Natl Acad Sci U S A (2011) 1.01
The midbody ring scaffolds the abscission machinery in the absence of midbody microtubules. J Cell Biol (2013) 0.98
The F-BAR domain of SRGP-1 facilitates cell-cell adhesion during C. elegans morphogenesis. J Cell Biol (2010) 0.95
Regulation of ubiquitin-dependent cargo sorting by multiple endocytic adaptors at the plasma membrane. Proc Natl Acad Sci U S A (2013) 0.93
Inhibition of TFG function causes hereditary axon degeneration by impairing endoplasmic reticulum structure. Proc Natl Acad Sci U S A (2013) 0.89
Early embryonic requirement for nucleoporin Nup35/NPP-19 in nuclear assembly. Dev Biol (2008) 0.88
Spatial control of phospholipid flux restricts endoplasmic reticulum sheet formation to allow nuclear envelope breakdown. Genes Dev (2014) 0.86
SORCS1 is necessary for normal insulin secretory granule biogenesis in metabolically stressed β cells. J Clin Invest (2014) 0.82
Roles of acidic phospholipids and nucleotides in regulating membrane binding and activity of a calcium-independent phospholipase A2 isoform. J Biol Chem (2012) 0.81
Worming our way in and out of the Caenorhabditis elegans germline and developing embryo. Traffic (2013) 0.80
The dual PH domain protein Opy1 functions as a sensor and modulator of PtdIns(4,5)P₂ synthesis. EMBO J (2012) 0.80
Sm protein down-regulation leads to defects in nuclear pore complex disassembly and distribution in C. elegans embryos. Dev Biol (2012) 0.78
The ins and outs of endocytic transport. Nat Cell Biol (2005) 0.76
The Noncanonical Role of ULK/ATG1 in ER-to-Golgi Trafficking Is Essential for Cellular Homeostasis. Mol Cell (2016) 0.76
Correction: Necrotic Cells Actively Attract Phagocytes through the Collaborative Action of Two Distinct PS-Exposure Mechanisms. PLoS Genet (2015) 0.76
Phosphoinositide signaling during membrane transport in Saccharomyces cerevisiae. Subcell Biochem (2012) 0.75