Linear coupling between cerebral blood flow and oxygen consumption in activated human cortex.

PubWeight™: 3.44‹?› | Rank: Top 1%

🔗 View Article (PMC 17795)

Published in Proc Natl Acad Sci U S A on August 03, 1999

Authors

R D Hoge1, J Atkinson, B Gill, G R Crelier, S Marrett, G B Pike

Author Affiliations

1: Room WB325, McConnell Brain Imaging Centre, Montreal Neurological Institute, Quebec, Canada H3A 2B4. rhoge@bic.mni.mcgill.ca

Articles citing this

(truncated to the top 100)

Mechanisms of migraine aura revealed by functional MRI in human visual cortex. Proc Natl Acad Sci U S A (2001) 3.51

The respiration response function: the temporal dynamics of fMRI signal fluctuations related to changes in respiration. Neuroimage (2007) 3.48

Diffuse Optics for Tissue Monitoring and Tomography. Rep Prog Phys (2010) 3.33

Retinal vascular image analysis as a potential screening tool for cerebrovascular disease: a rationale based on homology between cerebral and retinal microvasculatures. J Anat (2005) 3.02

Quantitative evaluation of oxygenation in venous vessels using T2-Relaxation-Under-Spin-Tagging MRI. Magn Reson Med (2008) 2.42

Contrast adaptation and representation in human early visual cortex. Neuron (2005) 2.17

Imaging oxygen consumption in forepaw somatosensory stimulation in rats under isoflurane anesthesia. Magn Reson Med (2004) 2.12

Spatio-temporal point-spread function of fMRI signal in human gray matter at 7 Tesla. Neuroimage (2007) 2.07

Coupling of functional connectivity and regional cerebral blood flow reveals a physiological basis for network hubs of the human brain. Proc Natl Acad Sci U S A (2013) 1.98

Common deactivation patterns during working memory and visual attention tasks: an intra-subject fMRI study at 4 Tesla. Hum Brain Mapp (2006) 1.96

Resting-state fMRI confounds and cleanup. Neuroimage (2013) 1.95

The QUASAR reproducibility study, Part II: Results from a multi-center Arterial Spin Labeling test-retest study. Neuroimage (2009) 1.92

A model of brain circulation and metabolism: NIRS signal changes during physiological challenges. PLoS Comput Biol (2008) 1.86

Biophysical and physiological origins of blood oxygenation level-dependent fMRI signals. J Cereb Blood Flow Metab (2012) 1.86

Effects of aging on cerebral blood flow, oxygen metabolism, and blood oxygenation level dependent responses to visual stimulation. Hum Brain Mapp (2009) 1.82

Reproducibility of BOLD, perfusion, and CMRO2 measurements with calibrated-BOLD fMRI. Neuroimage (2007) 1.77

Interpreting oxygenation-based neuroimaging signals: the importance and the challenge of understanding brain oxygen metabolism. Front Neuroenergetics (2010) 1.77

An approach to probe some neural systems interaction by functional MRI at neural time scale down to milliseconds. Proc Natl Acad Sci U S A (2000) 1.75

Pre-clinical PET/MR: technological advances and new perspectives in biomedical research. Eur J Nucl Med Mol Imaging (2009) 1.74

Activity-induced tissue oxygenation changes in rat cerebellar cortex: interplay of postsynaptic activation and blood flow. J Physiol (2005) 1.70

How and when the fMRI BOLD signal relates to underlying neural activity: the danger in dissociation. Brain Res Rev (2009) 1.70

A vascular anatomical network model of the spatio-temporal response to brain activation. Neuroimage (2008) 1.65

Caffeine-induced uncoupling of cerebral blood flow and oxygen metabolism: a calibrated BOLD fMRI study. Neuroimage (2007) 1.63

Total neuroenergetics support localized brain activity: implications for the interpretation of fMRI. Proc Natl Acad Sci U S A (2002) 1.62

The influence of moderate hypercapnia on neural activity in the anesthetized nonhuman primate. Cereb Cortex (2008) 1.56

Age-associated reductions in cerebral blood flow are independent from regional atrophy. Neuroimage (2010) 1.55

Comparison of time-frequency responses and the event-related potential to auditory speech stimuli in human cortex. J Neurophysiol (2009) 1.54

What's new in neuroimaging methods? Ann N Y Acad Sci (2009) 1.53

Metabolic and hemodynamic events after changes in neuronal activity: current hypotheses, theoretical predictions and in vivo NMR experimental findings. J Cereb Blood Flow Metab (2008) 1.47

13C MRS studies of neuroenergetics and neurotransmitter cycling in humans. NMR Biomed (2011) 1.47

Regional differences in the coupling of cerebral blood flow and oxygen metabolism changes in response to activation: implications for BOLD-fMRI. Neuroimage (2007) 1.45

Nonlinear coupling between cerebral blood flow, oxygen consumption, and ATP production in human visual cortex. Proc Natl Acad Sci U S A (2010) 1.44

Cortical layer-dependent dynamic blood oxygenation, cerebral blood flow and cerebral blood volume responses during visual stimulation. Neuroimage (2008) 1.42

Calibration and validation of TRUST MRI for the estimation of cerebral blood oxygenation. Magn Reson Med (2011) 1.40

Dynamics of changes in blood flow, volume, and oxygenation: implications for dynamic functional magnetic resonance imaging calibration. J Cereb Blood Flow Metab (2006) 1.38

Dynamic models of BOLD contrast. Neuroimage (2012) 1.32

Baseline blood oxygenation modulates response amplitude: Physiologic basis for intersubject variations in functional MRI signals. Magn Reson Med (2008) 1.27

A BOLD search for baseline. Neuroimage (2007) 1.26

Coupling between neuronal activity and microcirculation: implications for functional brain imaging. HFSP J (2008) 1.24

CBF/CMRO2 coupling measured with calibrated BOLD fMRI: sources of bias. Neuroimage (2007) 1.22

Oxidative neuroenergetics in event-related paradigms. J Neurosci (2009) 1.22

Hemodynamic and metabolic changes induced by cocaine in anesthetized rat observed with multimodal functional MRI. Psychopharmacology (Berl) (2006) 1.21

Energy metabolism of the visual system. Eye Brain (2010) 1.18

Cerebral blood flow and BOLD responses to a memory encoding task: a comparison between healthy young and elderly adults. Neuroimage (2007) 1.15

Cerebral blood flow and BOLD fMRI responses to hypoxia in awake and anesthetized rats. Brain Res (2007) 1.14

Evidence for a vascular contribution to diffusion FMRI at high b value. Proc Natl Acad Sci U S A (2007) 1.14

Mapping hypercapnia-induced cerebrovascular reactivity using BOLD MRI. Neuroradiology (2004) 1.14

Comparison of cerebral vascular reactivity measures obtained using breath-holding and CO2 inhalation. J Cereb Blood Flow Metab (2013) 1.12

Measurement of OEF and absolute CMRO2: MRI-based methods using interleaved and combined hypercapnia and hyperoxia. Neuroimage (2013) 1.11

Relations between BOLD fMRI-derived resting brain activity and cerebral blood flow. PLoS One (2012) 1.11

Direct estimation of evoked hemoglobin changes by multimodality fusion imaging. J Biomed Opt (2008) 1.11

Use of functional magnetic resonance imaging in the early identification of Alzheimer's disease. Neuropsychol Rev (2007) 1.11

The continuing challenge of understanding and modeling hemodynamic variation in fMRI. Neuroimage (2012) 1.10

CBF, BOLD, CBV, and CMRO(2) fMRI signal temporal dynamics at 500-msec resolution. J Magn Reson Imaging (2008) 1.09

New insights into central roles of cerebral oxygen metabolism in the resting and stimulus-evoked brain. J Cereb Blood Flow Metab (2008) 1.07

Quantitative basal CBF and CBF fMRI of rhesus monkeys using three-coil continuous arterial spin labeling. Neuroimage (2006) 1.07

Baseline CBF, and BOLD, CBF, and CMRO2 fMRI of visual and vibrotactile stimulations in baboons. J Cereb Blood Flow Metab (2010) 1.05

Mapping functional connectivity based on synchronized CMRO2 fluctuations during the resting state. Neuroimage (2009) 1.05

On improving the speed and reliability of T2-relaxation-under-spin-tagging (TRUST) MRI. Magn Reson Med (2011) 1.04

Assessing the physiological concentration and targets of nitric oxide in brain tissue. J Physiol (2008) 1.03

Somatosensory evoked changes in cerebral oxygen consumption measured non-invasively in premature neonates. Neuroimage (2013) 1.03

Neurovascular coupling to D2/D3 dopamine receptor occupancy using simultaneous PET/functional MRI. Proc Natl Acad Sci U S A (2013) 1.02

Magnetic resonance imaging of vascular oxygenation changes during hyperoxia and carbogen challenges in the human retina. Invest Ophthalmol Vis Sci (2011) 1.00

Improving fMRI sensitivity by normalization of basal physiologic state. Hum Brain Mapp (2010) 0.99

Quantitative fMRI and oxidative neuroenergetics. Neuroimage (2012) 0.98

Neurovascular factors in resting-state functional MRI. Neuroimage (2013) 0.98

Dynamics of oxygen delivery and consumption during evoked neural stimulation using a compartment model and CBF and tissue P(O2) measurements. Neuroimage (2008) 0.98

Effects of acetazolamide on the micro- and macro-vascular cerebral hemodynamics: a diffuse optical and transcranial doppler ultrasound study. Biomed Opt Express (2010) 0.97

The fMRI BOLD signal tracks electrophysiological spectral perturbations, not event-related potentials. Neuroimage (2011) 0.97

Neurovascular and Neurometabolic Couplings in Dynamic Calibrated fMRI: Transient Oxidative Neuroenergetics for Block-Design and Event-Related Paradigms. Front Neuroenergetics (2010) 0.96

Neurophysiology of functional imaging. Neuroimage (2008) 0.96

The oxygen paradox of neurovascular coupling. J Cereb Blood Flow Metab (2013) 0.95

Cerebral blood flow measurement using fMRI and PET: a cross-validation study. Int J Biomed Imaging (2008) 0.95

A neuronal basis for task-negative responses in the human brain. Cereb Cortex (2010) 0.95

Does functional MRI detect activation in white matter? A review of emerging evidence, issues, and future directions. Front Neurosci (2014) 0.94

Variability of the coupling of blood flow and oxygen metabolism responses in the brain: a problem for interpreting BOLD studies but potentially a new window on the underlying neural activity. Front Neurosci (2014) 0.94

A comparison of physiologic modulators of fMRI signals. Hum Brain Mapp (2012) 0.93

Anesthetic effects on regional CBF, BOLD, and the coupling between task-induced changes in CBF and BOLD: an fMRI study in normal human subjects. Magn Reson Med (2008) 0.93

Cerebrovascular reactivity in the brain white matter: magnitude, temporal characteristics, and age effects. J Cereb Blood Flow Metab (2013) 0.93

Neuroplasticity and functional recovery in multiple sclerosis. Nat Rev Neurol (2012) 0.93

Dopaminergic response to graded dopamine concentration elicited by four amphetamine doses. Synapse (2009) 0.92

Arterial spin labeling fMRI measurements of decreased blood flow in primary visual cortex correlates with decreased visual function in human glaucoma. Vision Res (2012) 0.92

Neural mechanisms of age-related slowing: the ΔCBF/ΔCMRO2 ratio mediates age-differences in BOLD signal and human performance. Cereb Cortex (2012) 0.91

Remifentanil administration reveals biphasic phMRI temporal responses in rat consistent with dynamic receptor regulation. Neuroimage (2006) 0.91

Spatial nonuniformity of the resting CBF and BOLD responses to sevoflurane: in vivo study of normal human subjects with magnetic resonance imaging. Hum Brain Mapp (2008) 0.91

A New Functional MRI Approach for Investigating Modulations of Brain Oxygen Metabolism. PLoS One (2013) 0.91

A BOLD Perspective on Age-Related Neurometabolic-Flow Coupling and Neural Efficiency Changes in Human Visual Cortex. Front Psychol (2013) 0.90

Similarities and differences in arterial responses to hypercapnia and visual stimulation. J Cereb Blood Flow Metab (2010) 0.90

Low-frequency calcium oscillations accompany deoxyhemoglobin oscillations in rat somatosensory cortex. Proc Natl Acad Sci U S A (2014) 0.89

Sensitivity of neural-hemodynamic coupling to alterations in cerebral blood flow during hypercapnia. J Biomed Opt (2009) 0.89

Calibrated fMRI in the medial temporal lobe during a memory-encoding task. Neuroimage (2008) 0.89

Depression of cortical activity in humans by mild hypercapnia. Hum Brain Mapp (2011) 0.89

Diffusion tensor and perfusion MRI of non-human primates. Methods (2009) 0.88

The impact of a sports vision training program in youth field hockey players. J Sports Sci Med (2012) 0.88

Physiologic underpinnings of negative BOLD cerebrovascular reactivity in brain ventricles. Neuroimage (2013) 0.88

Luminance contrast of a visual stimulus modulates the BOLD response more than the cerebral blood flow response in the human brain. Neuroimage (2012) 0.87

Insights from neuroenergetics into the interpretation of functional neuroimaging: an alternative empirical model for studying the brain's support of behavior. J Cereb Blood Flow Metab (2014) 0.87

A nonlinear dynamic approach reveals a long-term stroke effect on cerebral blood flow regulation at multiple time scales. PLoS Comput Biol (2012) 0.86

Indication of BOLD-specific venous flow-volume changes from precisely controlled hyperoxic vs. hypercapnic calibration. J Cereb Blood Flow Metab (2011) 0.86

The effects of capillary transit time heterogeneity (CTH) on brain oxygenation. J Cereb Blood Flow Metab (2015) 0.85

Articles cited by this

THE EFFECTS OF ALTERED ARTERIAL TENSIONS OF CARBON DIOXIDE AND OXYGEN ON CEREBRAL BLOOD FLOW AND CEREBRAL OXYGEN CONSUMPTION OF NORMAL YOUNG MEN. J Clin Invest (1948) 22.75

Automatic 3D intersubject registration of MR volumetric data in standardized Talairach space. J Comput Assist Tomogr (1994) 15.38

Intrinsic signal changes accompanying sensory stimulation: functional brain mapping with magnetic resonance imaging. Proc Natl Acad Sci U S A (1992) 14.96

Borders of multiple visual areas in humans revealed by functional magnetic resonance imaging. Science (1995) 12.98

Nonoxidative glucose consumption during focal physiologic neural activity. Science (1988) 9.59

Focal physiological uncoupling of cerebral blood flow and oxidative metabolism during somatosensory stimulation in human subjects. Proc Natl Acad Sci U S A (1986) 9.31

Functional brain mapping by blood oxygenation level-dependent contrast magnetic resonance imaging. A comparison of signal characteristics with a biophysical model. Biophys J (1993) 6.52

Calibrated functional MRI: mapping the dynamics of oxidative metabolism. Proc Natl Acad Sci U S A (1998) 6.02

Interactions between electrical activity and cortical microcirculation revealed by imaging spectroscopy: implications for functional brain mapping. Science (1996) 5.40

The effects of changes in PaCO2 on cerebral blood volume, blood flow, and vascular mean transit time. Stroke (1974) 4.89

Quantification of relative cerebral blood flow change by flow-sensitive alternating inversion recovery (FAIR) technique: application to functional mapping. Magn Reson Med (1995) 4.56

Behind the scenes of functional brain imaging: a historical and physiological perspective. Proc Natl Acad Sci U S A (1998) 4.35

Functional analysis of V3A and related areas in human visual cortex. J Neurosci (1997) 3.33

A model for the coupling between cerebral blood flow and oxygen metabolism during neural stimulation. J Cereb Blood Flow Metab (1997) 3.20

Lactate rise detected by 1H NMR in human visual cortex during physiologic stimulation. Proc Natl Acad Sci U S A (1991) 2.91

Quantitative assessment of blood flow, blood volume and blood oxygenation effects in functional magnetic resonance imaging. Nat Med (1998) 2.87

The intravascular contribution to fMRI signal change: Monte Carlo modeling and diffusion-weighted studies in vivo. Magn Reson Med (1995) 2.59

Dynamic uncoupling and recoupling of perfusion and oxidative metabolism during focal brain activation in man. Magn Reson Med (1996) 2.02

Does mental activity change the oxidative metabolism of the brain? J Neurosci (1987) 1.99

Comparison of blood oxygenation and cerebral blood flow effects in fMRI: estimation of relative oxygen consumption change. Magn Reson Med (1997) 1.90

Effect of photic stimulation on human visual cortex lactate and phosphates using 1H and 31P magnetic resonance spectroscopy. J Cereb Blood Flow Metab (1992) 1.86

Stimulus rate determines regional brain blood flow in striate cortex. Ann Neurol (1985) 1.85

Persistent resetting of the cerebral oxygen/glucose uptake ratio by brain activation: evidence obtained with the Kety-Schmidt technique. J Cereb Blood Flow Metab (1995) 1.82

Functional anatomy of macaque striate cortex. V. Spatial frequency. J Neurosci (1988) 1.61

What makes brain neurons run? Science (1997) 1.57

A model for the regulation of cerebral oxygen delivery. J Appl Physiol (1985) (1998) 1.49

Cellular bases of brain energy metabolism and their relevance to functional brain imaging: evidence for a prominent role of astrocytes. Cereb Cortex (1996) 1.44

Cerebral blood flow and metabolism: effects of anesthetic drugs and techniques. Anesthesiology (1972) 1.39

Vibratory stimulation increases and decreases the regional cerebral blood flow and oxidative metabolism: a positron emission tomography (PET) study. Acta Neurol Scand (1992) 1.30

Cerebral blood flow and metabolic responses to sustained hypercapnia in awake sheep. J Cereb Blood Flow Metab (1995) 1.29

Cerebral circulation and metabolism during thiopental anesthesia and hyper-ventilation in man. J Clin Invest (1962) 1.28

Stimulus-dependent BOLD and perfusion dynamics in human V1. Neuroimage (1999) 1.24

Blood flow in single surface arterioles and venules on the mouse somatosensory cortex measured with videomicroscopy, fluorescent dextrans, nonoccluding fluorescent beads, and computer-assisted image analysis. J Cereb Blood Flow Metab (1993) 1.14

Cerebral hyperemia in electrically induced epileptic seizures. Arch Neurol (1973) 1.14

Functional anatomy of macaque striate cortex. III. Color. J Neurosci (1988) 1.10

Frequency-dependent changes in cerebral metabolic rate of oxygen during activation of human visual cortex. J Cereb Blood Flow Metab (1999) 1.09

Rate dependence of regional cerebral activation during performance of a repetitive motor task: a PET study. J Cereb Blood Flow Metab (1996) 1.04

Comparison of EPI gradient-echo contrast changes in cat brain caused by respiratory challenges with direct simultaneous evaluation of cerebral oxygenation via a cranial window. NMR Biomed (1994) 1.03

Mathematical model of oxygen transport in the cerebral cortex. Brain Res (1999) 1.01

Frequency-dependent changes of regional cerebral blood flow during finger movements. J Cereb Blood Flow Metab (1996) 1.00

Oxygen consumption of cerebral cortex fails to increase during continued vibrotactile stimulation. J Cereb Blood Flow Metab (1999) 0.99

Simultaneous oxygenation and perfusion imaging study of functional activity in primary visual cortex at different visual stimulation frequency: quantitative correlation between BOLD and CBF changes. Magn Reson Med (1998) 0.97

MRI measurements of cerebral deoxyhaemoglobin concentration [dHb]--correlation with near infrared spectroscopy (NIRS). NMR Biomed (1998) 0.94

Increased oxygen consumption in human visual cortex: response to visual stimulation. Acta Neurol Scand (1998) 0.93

Characterizing the relationship between BOLD contrast and regional cerebral blood flow measurements by varying the stimulus presentation rate. Neuroimage (1997) 0.93

Changes of blood flow and oxygen consumption in visual cortex of living humans. Adv Exp Med Biol (1997) 0.90

Cerebral blood flow and metabolism in schizophrenia; the effects of barbiturate semi-narcosis, insulin coma and electroshock. Am J Psychiatry (1948) 0.90

The effects of cyclopropane on cerebral and systemic carbohydrate metabolism. Anesthesiology (1970) 0.88

Perfusion-based functional magnetic resonance imaging with single-shot RARE and GRASE acquisitions. Magn Reson Med (1999) 0.87

Investigating the dependence of BOLD contrast on oxidative metabolism. Magn Reson Med (1999) 0.85

Brief vibrotactile stimulation does not increase cortical oxygen consumption when measured by single inhalation of positron emitting oxygen. J Cereb Blood Flow Metab (1999) 0.82

Articles by these authors

A unified statistical approach for determining significant signals in images of cerebral activation. Hum Brain Mapp (1996) 13.15

A three-dimensional statistical analysis for CBF activation studies in human brain. J Cereb Blood Flow Metab (1992) 11.25

Unemployment and suicide. Evidence for a causal association? J Epidemiol Community Health (2003) 4.70

A general mechanism for perceptual decision-making in the human brain. Nature (2004) 3.82

Socioeconomic status, standard of living, and neurotic disorder. Lancet (1998) 3.80

Randomised trial of isoniazid versus rifampicin and pyrazinamide for prevention of tuberculosis in HIV-1 infection. Lancet (1998) 3.37

Investigation of BOLD signal dependence on cerebral blood flow and oxygen consumption: the deoxyhemoglobin dilution model. Magn Reson Med (1999) 3.26

The retinotopy of visual spatial attention. Neuron (1998) 3.18

MRI simulation-based evaluation of image-processing and classification methods. IEEE Trans Med Imaging (1999) 3.16

The National Psychiatric Morbidity surveys of Great Britain--initial findings from the household survey. Psychol Med (1997) 2.74

Multiple representations of pain in human cerebral cortex. Science (1991) 2.74

Anatomical mapping of functional activation in stereotactic coordinate space. Neuroimage (1992) 2.37

Quantitative imaging of magnetization transfer exchange and relaxation properties in vivo using MRI. Magn Reson Med (2001) 2.22

Involvement of human left dorsolateral prefrontal cortex in perceptual decision making is independent of response modality. Proc Natl Acad Sci U S A (2006) 2.11

Gastric emptying and motility: assessment with MR imaging--preliminary observations. Radiology (1998) 2.10

Quantitative interpretation of magnetization transfer in spoiled gradient echo MRI sequences. J Magn Reson (2000) 2.09

Standing-wave and RF penetration artifacts caused by elliptic geometry: an electrodynamic analysis of MRI. IEEE Trans Med Imaging (1998) 1.74

Diffusion tensor imaging, permanent pyramidal tract damage, and outcome in subcortical stroke. Neurology (2010) 1.64

Factors influencing antibiotic prescribing habits and use of sensitivity testing amongst veterinarians in Europe. Vet Rec (2013) 1.60

Regional hemodynamic responses to visual stimulation in awake infants. Pediatr Res (1998) 1.59

Plastid-localized acetyl-CoA carboxylase of bread wheat is encoded by a single gene on each of the three ancestral chromosome sets. Proc Natl Acad Sci U S A (1997) 1.58

Infant astigmatism: its disappearance with age. Vision Res (1980) 1.55

Asthma at the interface: bridging the gap between general practice and a district general hospital. Arch Dis Child (1994) 1.51

Screening for refractive errors in 6-9 month old infants by photorefraction. Br J Ophthalmol (1984) 1.50

Autopsy risk and acquisition of human immunodeficiency virus infection: a case report and reappraisal. Arch Pathol Lab Med (1997) 1.49

Motion processing in autism: evidence for a dorsal stream deficiency. Neuroreport (2000) 1.48

Duplication of 7q34 is specific to juvenile pilocytic astrocytomas and a hallmark of cerebellar and optic pathway tumours. Br J Cancer (2009) 1.48

Six-month supervised intermittent tuberculosis therapy in Haitian patients with and without HIV infection. Am J Respir Crit Care Med (1996) 1.48

The cortical deficit in humans with strabismic amblyopia. J Physiol (2001) 1.44

Development of contrast sensitivity over the first 3 months of life in the human infant. Vision Res (1977) 1.43

Infant emmetropization: longitudinal changes in refraction components from nine to twenty months of age. Optom Vis Sci (1997) 1.42

MRI-PET correlation in three dimensions using a volume-of-interest (VOI) atlas. J Cereb Blood Flow Metab (1991) 1.40

Comparison of chromosome telomere integrity in multiple tissues from subjects at different ages. Cancer Genet Cytogenet (1998) 1.39

A novel technique for correction of intestinal atresia at the ligament of Treitz. J Pediatr Surg (2000) 1.38

Searching scale space for activation in PET images. Hum Brain Mapp (1996) 1.37

Calcification of medial elastic fibers and aortic elasticity. Hypertension (1997) 1.37

Intrathecal baclofen for intractable spasticity of spinal origin: results of a long-term multicenter study. J Neurosurg (1993) 1.36

A quantitative study of the anticholinergic action of several tricyclic antidepressants on the rat isolated fundal strip. Br J Pharmacol (1972) 1.36

PRESTO-SENSE: an ultrafast whole-brain fMRI technique. Magn Reson Med (2000) 1.35

The National Psychiatric Morbidity surveys of Great Britain--strategy and methods. Psychol Med (1997) 1.34

Validity of short food frequency questionnaires used in cancer chemoprevention trials: results from the Prostate Cancer Prevention Trial. Cancer Epidemiol Biomarkers Prev (1999) 1.33

Brain areas sensitive to coherent visual motion. Perception (2001) 1.29

Texture analysis and morphological processing of magnetic resonance imaging assist detection of focal cortical dysplasia in extra-temporal partial epilepsy. Ann Neurol (2001) 1.29

From retinotopy to recognition: fMRI in human visual cortex. Trends Cogn Sci (1998) 1.26

Fifth report of The Human Kidney Transplant Registry. Transplantation (1967) 1.25

The magic number 4 +/- 0: a new look at visual numerosity judgements. Perception (1976) 1.25

Aortic wall mechanics and composition in a transgenic mouse model of Marfan syndrome. Arterioscler Thromb Vasc Biol (2001) 1.25

Stimulus-dependent BOLD and perfusion dynamics in human V1. Neuroimage (1999) 1.24

Sex differences in the growth of white matter during adolescence. Neuroimage (2009) 1.23

Chromosome mapping and phylogenetic analysis of the cytosolic acetyl-CoA carboxylase loci in wheat. Mol Biol Evol (2001) 1.23

Mathematical methods for diffusion MRI processing. Neuroimage (2008) 1.23

Context effects on misreading and suppression at UAG codons in human cells. Mol Cell Biol (1995) 1.22

Regional variations in normal brain shown by quantitative magnetization transfer imaging. Magn Reson Med (2004) 1.21

Human visual development over the first 6 months of life. A review and a hypothesis. Hum Neurobiol (1984) 1.21

Glycolysis in neurons, not astrocytes, delays oxidative metabolism of human visual cortex during sustained checkerboard stimulation in vivo. J Cereb Blood Flow Metab (2001) 1.18

Serial electrocardiographic changes in idiopathic dilated cardiomyopathy confirmed at necropsy. Am J Cardiol (1988) 1.18

Complement activation in very early Alzheimer disease. Alzheimer Dis Assoc Disord (2005) 1.18

Form and motion coherence activate independent, but not dorsal/ventral segregated, networks in the human brain. Curr Biol (2000) 1.16

Sexual dimorphism in the adolescent brain: Role of testosterone and androgen receptor in global and local volumes of grey and white matter. Horm Behav (2009) 1.16

Signifance of faecoliths in the diagnosis of acute appendicitis. Br J Surg (1975) 1.13

Plasticity of the human motor cortex in patients with arteriovenous malformations: a functional MR imaging study. AJNR Am J Neuroradiol (2000) 1.12

Cerebroretinal vasculopathy. A new hereditary syndrome. Ophthalmology (1988) 1.12

Local and global attention are mapped retinotopically in human occipital cortex. Proc Natl Acad Sci U S A (2001) 1.10

Substance misuse and psychiatric comorbidity: an overview of the OPCS National Psychiatric Morbidity Survey. Addict Behav (1999) 1.10

Basal ganglia damage and impaired visual function in the newborn infant. Arch Dis Child Fetal Neonatal Ed (1997) 1.09

Frequency-dependent changes in cerebral metabolic rate of oxygen during activation of human visual cortex. J Cereb Blood Flow Metab (1999) 1.09

Radiosurgery with high energy photon beams: a comparison among techniques. Int J Radiat Oncol Biol Phys (1989) 1.09

A photorefractive study of infant accommodation. Vision Res (1979) 1.09

Scrotal abscess following appendectomy. Pediatr Surg Int (2001) 1.09

No association of income inequality with adult mortality within New Zealand: a multi-level study of 1.4 million 25-64 year olds. J Epidemiol Community Health (2003) 1.08

Estimation of myocardial interstitial norepinephrine release after brain death using cardiac microdialysis. Transplantation (1994) 1.07

The National Psychiatric Morbidity Surveys of Great Britain--initial findings from the household survey. Int Rev Psychiatry (2004) 1.06

Attenuation of the baroreceptor reflex by general anesthetic agents in the normotensive rat. Eur J Pharmacol (1985) 1.06

An inverse problem approach to the correction of distortion in EPI images. IEEE Trans Med Imaging (2000) 1.05

An ongoing large outbreak of measles in Merseyside, England, January to June 2012. Euro Surveill (2012) 1.04

Widespread HIV counseling and testing linked to a community-based tuberculosis control program in a high-risk population. Bull Pan Am Health Organ (1996) 1.04

Three-point phase-contrast velocity measurements with increased velocity-to-noise ratio. Magn Reson Med (1995) 1.03

Resolving fiber crossing using advanced fast marching tractography based on diffusion tensor imaging. Neuroimage (2005) 1.03

Correction for B(1) and B(0) variations in quantitative T(2) measurements using MRI. Magn Reson Med (2000) 1.03

Anatomical-functional correlation using an adjustable MRI-based region of interest atlas with positron emission tomography. J Cereb Blood Flow Metab (1988) 1.02

Visual function in full-term infants with hypoxic-ischaemic encephalopathy. Neuropediatrics (1997) 1.02

Infant astigmatism measured by photorefraction. Science (1978) 1.01

Steroscopic discrimination in infants. Perception (1976) 1.00

Urolithiasis in children following augmentation cystoplasty. J Urol (1993) 0.99

Quantitative magnetic resonance imaging in the assessment of degenerative disc disease. Magn Reson Med (1998) 0.97

Extraretinal modulation of cerebral blood flow in the human visual cortex: implications for saccadic suppression. J Neurophysiol (1995) 0.97

Impaired plasma membrane targeting of Grb2-murine son of sevenless (mSOS) complex and differential activation of the Fyn-T cell receptor (TCR)-zeta-Cbl pathway mediate T cell hyporesponsiveness in autoimmune nonobese diabetic mice. J Exp Med (1997) 0.97

The accessibility of information systems for patients: use of touchscreen information systems by 345 patients with cancer in Scotland. Proc AMIA Symp (1999) 0.97

Does the Catford drum give an accurate assessment of acuity? Br J Ophthalmol (1981) 0.97

Visual function and perinatal focal cerebral infarction. Arch Dis Child Fetal Neonatal Ed (1996) 0.97

Density compensation functions for spiral MRI. Magn Reson Med (1997) 0.97