Construction of a recombinant adeno-associated virus (rAAV) vector expressing murine interleukin-12 (IL-12).

PubWeight™: 0.82‹?›

🔗 View Article (PMID 10770641)

Published in Cancer Gene Ther on February 01, 2000

Authors

D Paul1, M H Qazilbash, K Song, H Xu, B K Sinha, J Liu, K H Cowan

Author Affiliations

1: Medicine Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

Articles by these authors

The transcriptional landscape of the mammalian genome. Science (2005) 37.63

Systematic genetic analysis with ordered arrays of yeast deletion mutants. Science (2001) 24.48

fw2.2: a quantitative trait locus key to the evolution of tomato fruit size. Science (2000) 7.91

A novel role for 3-O-sulfated heparan sulfate in herpes simplex virus 1 entry. Cell (1999) 6.82

Alpha-5/alpha-3 nicotinic receptor subunit alleles increase risk for heavy smoking. Mol Psychiatry (2008) 6.37

Leptin-regulated endocannabinoids are involved in maintaining food intake. Nature (2001) 6.36

Prevention of graft versus host disease by inactivation of host antigen-presenting cells. Science (1999) 6.02

Digital tomosynthesis in breast imaging. Radiology (1997) 5.82

Atomic structure of a thermostable subdomain of HIV-1 gp41. Proc Natl Acad Sci U S A (1997) 5.76

Self-monitoring of blood glucose levels and glycemic control: the Northern California Kaiser Permanente Diabetes registry. Am J Med (2001) 5.68

Pigment epithelium-derived factor: a potent inhibitor of angiogenesis. Science (1999) 5.53

Separation of caveolae from associated microdomains of GPI-anchored proteins. Science (1995) 5.25

High fertilization and implantation rates after intracytoplasmic sperm injection. Hum Reprod (1993) 5.06

Comparing sequenced segments of the tomato and Arabidopsis genomes: large-scale duplication followed by selective gene loss creates a network of synteny. Proc Natl Acad Sci U S A (2000) 4.90

Comparative efficacy of adjuvant chemotherapy in patients with Dukes' B versus Dukes' C colon cancer: results from four National Surgical Adjuvant Breast and Bowel Project adjuvant studies (C-01, C-02, C-03, and C-04) J Clin Oncol (1999) 4.79

TBX1 is responsible for cardiovascular defects in velo-cardio-facial/DiGeorge syndrome. Cell (2001) 4.60

A prokaryotic voltage-gated sodium channel. Science (2001) 4.56

Genetic analysis of novel avian A(H7N9) influenza viruses isolated from patients in China, February to April 2013. Euro Surveill (2013) 4.44

Genome sequence, comparative analysis, and population genetics of the domestic horse. Science (2009) 4.41

Activation of Arp2/3 complex-mediated actin polymerization by cortactin. Nat Cell Biol (2001) 4.38

Comorbidity of DSM-III-R major depressive disorder in the general population: results from the US National Comorbidity Survey. Br J Psychiatry Suppl (1996) 3.99

Intraneuronal Abeta42 accumulation in human brain. Am J Pathol (2000) 3.83

Targeting of nitric oxide synthase to endothelial cell caveolae via palmitoylation: implications for nitric oxide signaling. Proc Natl Acad Sci U S A (1996) 3.83

Ultralong single-wall carbon nanotubes. Nat Mater (2004) 3.83

TWEAK, a new secreted ligand in the tumor necrosis factor family that weakly induces apoptosis. J Biol Chem (1997) 3.81

Function of GATA transcription factors in preadipocyte-adipocyte transition. Science (2000) 3.60

A prognostic score for patients with lower risk myelodysplastic syndrome. Leukemia (2007) 3.45

Ten-year results of a comparison of conservation with mastectomy in the treatment of stage I and II breast cancer. N Engl J Med (1995) 3.43

Proton-pump inhibitors and risk of fractures: an update meta-analysis. Osteoporos Int (2016) 3.30

Developing a prediction rule from automated clinical databases to identify high-risk patients in a large population with diabetes. Diabetes Care (2001) 3.27

A point mutation in the neu oncogene mimics ligand induction of receptor aggregation. Nature (1989) 3.27

Genetic analysis of salt tolerance in arabidopsis. Evidence for a critical role of potassium nutrition. Plant Cell (1998) 3.25

The crystal structure of a T cell receptor in complex with peptide and MHC class II. Science (1999) 3.23

The major facilitator superfamily. J Mol Microbiol Biotechnol (1999) 3.17

Optimizing drug outcomes through pharmacogenetics: a case for preemptive genotyping. Clin Pharmacol Ther (2012) 3.16

Prevalence of diabetes and its risk factors in China, 1994. National Diabetes Prevention and Control Cooperative Group. Diabetes Care (1997) 3.03

Endothelial nitric oxide synthase is regulated by tyrosine phosphorylation and interacts with caveolin-1. J Biol Chem (1996) 3.01

Acupuncture modulates the limbic system and subcortical gray structures of the human brain: evidence from fMRI studies in normal subjects. Hum Brain Mapp (2000) 2.98

Immunohistochemical analysis of bcl-2, bax, bcl-X, and mcl-1 expression in prostate cancers. Am J Pathol (1996) 2.97

Metallothionein: an intracellular protein to protect against cadmium toxicity. Annu Rev Pharmacol Toxicol (1999) 2.95

Molecular cloning of caveolin-3, a novel member of the caveolin gene family expressed predominantly in muscle. J Biol Chem (1996) 2.95

The emerging role of electronic medical records in pharmacogenomics. Clin Pharmacol Ther (2011) 2.93

Genetic architecture of a morphological shape difference between two Drosophila species. Genetics (2000) 2.92

New tumor markers: CA125 and beyond. Int J Gynecol Cancer (2005) 2.92

SOS3 function in plant salt tolerance requires N-myristoylation and calcium binding. Plant Cell (2000) 2.91

Human RNase III is a 160-kDa protein involved in preribosomal RNA processing. J Biol Chem (2000) 2.88

Prominent neutrophilic inflammation in sputum from subjects with asthma exacerbation. J Allergy Clin Immunol (1995) 2.88

Overexpression of a novel anionic glutathione transferase in multidrug-resistant human breast cancer cells. J Biol Chem (1986) 2.88

Essential function of Gli2 and Gli3 in the formation of lung, trachea and oesophagus. Nat Genet (1998) 2.87

Endocrine manifestations of stimulatory G protein alpha-subunit mutations and the role of genomic imprinting. Endocr Rev (2001) 2.84

Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation. Oncogene (2012) 2.82

Dentinogenesis imperfecta 1 with or without progressive hearing loss is associated with distinct mutations in DSPP. Nat Genet (2001) 2.75

Toxicity of ALS-linked SOD1 mutants. Science (2000) 2.69

Survival of recipients of livers from donation after circulatory death who are relisted and undergo retransplant for graft failure. Am J Transplant (2014) 2.67

Sino-MONICA project: a collaborative study on trends and determinants in cardiovascular diseases in China, Part i: morbidity and mortality monitoring. Circulation (2001) 2.56

Molecular cloning and functional expression of a mu-opioid receptor from rat brain. Mol Pharmacol (1993) 2.54

SCH-C (SCH 351125), an orally bioavailable, small molecule antagonist of the chemokine receptor CCR5, is a potent inhibitor of HIV-1 infection in vitro and in vivo. Proc Natl Acad Sci U S A (2001) 2.49

Functional knockout of the transient outward current, long-QT syndrome, and cardiac remodeling in mice expressing a dominant-negative Kv4 alpha subunit. Circ Res (1998) 2.48

Intracytoplasmic single sperm injection of 1-day-old unfertilized human oocytes. Hum Reprod (1993) 2.46

Activation of NF-kappa B by nontypeable Hemophilus influenzae is mediated by toll-like receptor 2-TAK1-dependent NIK-IKK alpha /beta-I kappa B alpha and MKK3/6-p38 MAP kinase signaling pathways in epithelial cells. Proc Natl Acad Sci U S A (2001) 2.46

Endothelial caveolae have the molecular transport machinery for vesicle budding, docking, and fusion including VAMP, NSF, SNAP, annexins, and GTPases. J Biol Chem (1995) 2.41

Crystal structure of the unique RNA-binding domain of the influenza virus NS1 protein. Nat Struct Biol (1997) 2.41

CDC14 of Saccharomyces cerevisiae. Cloning, sequence analysis, and transcription during the cell cycle. J Biol Chem (1992) 2.41

The role of tyrosine phosphorylation of cortactin in the locomotion of endothelial cells. J Biol Chem (1998) 2.39

Bacterial lipopolysaccharide and IFN-gamma induce Toll-like receptor 2 and Toll-like receptor 4 expression in human endothelial cells: role of NF-kappa B activation. J Immunol (2001) 2.37

Exploration of antigenic variation in gp120 from clades A through F of human immunodeficiency virus type 1 by using monoclonal antibodies. J Virol (1994) 2.36

Predicting clopidogrel response using DNA samples linked to an electronic health record. Clin Pharmacol Ther (2011) 2.36

Cellular and biochemical analysis of induced sputum from asthmatic and from healthy subjects. Am Rev Respir Dis (1993) 2.34

Epidemiological link between exposure to poultry and all influenza A(H7N9) confirmed cases in Huzhou city, China, March to May 2013. Euro Surveill (2013) 2.34

Inner ear defects induced by null mutation of the isk gene. Neuron (1996) 2.34

Regulation of adhesion of ICAM-1 by the cytoplasmic domain of LFA-1 integrin beta subunit. Science (1991) 2.34

Risk prediction of prevalent diabetes in a Swiss population using a weighted genetic score--the CoLaus Study. Diabetologia (2009) 2.32

Gate-voltage control of chemical potential and weak antilocalization in Bi₂Se₃. Phys Rev Lett (2010) 2.32

Platelet glycoprotein ibalpha is a counterreceptor for the leukocyte integrin Mac-1 (CD11b/CD18). J Exp Med (2000) 2.31

Scaffold proteins of MAP-kinase modules. Oncogene (2007) 2.30

The pharmacology and clinical use of methotrexate. N Engl J Med (1983) 2.29

Human DNA replication initiation factors, ORC and MCM, associate with oriP of Epstein-Barr virus. Proc Natl Acad Sci U S A (2001) 2.24

A comparative linkage map of oilseed rape and its use for QTL analysis of seed oil and erucic acid content. Theor Appl Genet (2006) 2.21

The Golgi association of endothelial nitric oxide synthase is necessary for the efficient synthesis of nitric oxide. J Biol Chem (1995) 2.20

The cytoplasmic peptidoglycan precursor of vancomycin-resistant Enterococcus faecalis terminates in lactate. J Bacteriol (1992) 2.20

Classification and 3D averaging with missing wedge correction in biological electron tomography. J Struct Biol (2008) 2.19

Formation of a gated channel by a ligand-specific transport protein in the bacterial outer membrane. Science (1992) 2.19

Identification of conserved and variant epitopes of human immunodeficiency virus type 1 (HIV-1) gp120 by human monoclonal antibodies produced by EBV-transformed cell lines. AIDS Res Hum Retroviruses (1990) 2.18

Surveillance of the first case of human avian influenza A (H7N9) virus in Beijing, China. Infection (2013) 2.18

An introgression analysis of quantitative trait loci that contribute to a morphological difference between Drosophila simulans and D. mauritiana. Genetics (1997) 2.17

Histone deacetylase inhibition selectively alters the activity and expression of cell cycle proteins leading to specific chromatin acetylation and antiproliferative effects. J Biol Chem (1999) 2.14

The DNA replication protein PriA and the recombination protein RecG bind D-loops. J Mol Biol (1997) 2.13

Dynamic evolution of plant mitochondrial genomes: mobile genes and introns and highly variable mutation rates. Proc Natl Acad Sci U S A (2000) 2.13

C. elegans nuclear envelope proteins emerin, MAN1, lamin, and nucleoporins reveal unique timing of nuclear envelope breakdown during mitosis. Mol Biol Cell (2000) 2.11

A general method for the chromosomal amplification of genes in yeast. Science (1988) 2.07

Transport of vesicular stomatitis virus G protein to the cell surface is signal mediated in polarized and nonpolarized cells. J Cell Biol (1996) 2.06

Identification of a breast cancer-specific gene, BCSG1, by direct differential cDNA sequencing. Cancer Res (1997) 2.05

Automatic prediction of protein function. Cell Mol Life Sci (2003) 2.03

Higher success rate by intracytoplasmic sperm injection than by subzonal insemination. Report of a second series of 300 consecutive treatment cycles. Hum Reprod (1993) 2.02

Evaluation of estrogenic activity of plant extracts for the potential treatment of menopausal symptoms. J Agric Food Chem (2001) 2.02

Axl as a potential therapeutic target in cancer: role of Axl in tumor growth, metastasis and angiogenesis. Oncogene (2009) 2.01

Caveolin-1 expression negatively regulates cell cycle progression by inducing G(0)/G(1) arrest via a p53/p21(WAF1/Cip1)-dependent mechanism. Mol Biol Cell (2001) 2.00

Neonatal blood: a source of haematopoietic stem cells for transplantation? Lancet (1998) 1.99

Molecular basis of transient outward K+ current diversity in mouse ventricular myocytes. J Physiol (1999) 1.99