Published in Eur J Clin Microbiol Infect Dis on March 01, 2000
Peptide antimicrobial agents. Clin Microbiol Rev (2006) 6.04
Cathelicidin deficiency predisposes to eczema herpeticum. J Allergy Clin Immunol (2006) 1.88
Membrane-dependent oligomeric structure and pore formation of a beta-hairpin antimicrobial peptide in lipid bilayers from solid-state NMR. Proc Natl Acad Sci U S A (2006) 1.87
Applications of biological pores in nanomedicine, sensing, and nanoelectronics. Curr Opin Biotechnol (2010) 1.66
Theta defensins protect cells from infection by herpes simplex virus by inhibiting viral adhesion and entry. J Virol (2004) 1.58
Human cathelicidin (LL-37), a multifunctional peptide, is expressed by ocular surface epithelia and has potent antibacterial and antiviral activity. Curr Eye Res (2005) 1.58
Antiviral activity and increased host defense against influenza infection elicited by the human cathelicidin LL-37. PLoS One (2011) 1.39
Antimicrobial peptides. Pharmaceuticals (Basel) (2013) 1.37
Development of topical microbicides to prevent the sexual transmission of HIV. Antiviral Res (2009) 1.30
Antimicrobial peptides from amphibian skin potently inhibit human immunodeficiency virus infection and transfer of virus from dendritic cells to T cells. J Virol (2005) 1.23
Anti-human immunodeficiency virus type 1 activities of antimicrobial peptides derived from human and bovine cathelicidins. Antimicrob Agents Chemother (2008) 1.20
Human alpha-defensins inhibit BK virus infection by aggregating virions and blocking binding to host cells. J Biol Chem (2008) 1.12
Therapeutic Potential of Plants as Anti-microbials for Drug Discovery. Evid Based Complement Alternat Med (2008) 1.07
A lipid-peptide microbicide inactivates herpes simplex virus. Antimicrob Agents Chemother (2004) 0.98
Current scenario of peptide-based drugs: the key roles of cationic antitumor and antiviral peptides. Front Microbiol (2013) 0.98
Peptide-based Antifungal Therapies against Emerging Infections. Drugs Future (2010) 0.97
Safety, formulation, and in vitro antiviral activity of the antimicrobial peptide subtilosin against herpes simplex virus type 1. Probiotics Antimicrob Proteins (2013) 0.92
Ostreid herpesvirus type 1 replication and host response in adult Pacific oysters, Crassostrea gigas. Vet Res (2014) 0.87
A 3-O-sulfated heparan sulfate binding peptide preferentially targets herpes simplex virus 2-infected cells. J Virol (2012) 0.85
The oncolytic peptide LTX-315 induces cell death and DAMP release by mitochondria distortion in human melanoma cells. Oncotarget (2015) 0.83
Update on emerging antivirals for the management of herpes simplex virus infections: a patenting perspective. Recent Pat Antiinfect Drug Discov (2013) 0.81
Enhancement of antiviral activity of human alpha-defensin 5 against herpes simplex virus 2 by arginine mutagenesis at adaptive evolution sites. J Virol (2012) 0.79
Therapeutic approaches using host defence peptides to tackle herpes virus infections. Viruses (2009) 0.78
Inhibition of dengue virus entry into target cells using synthetic antiviral peptides. Int J Med Sci (2013) 0.77
Antiviral activity of animal venom peptides and related compounds. J Venom Anim Toxins Incl Trop Dis (2017) 0.75
Interaction of Candida albicans with human leukocytes and serum. J Bacteriol (1969) 9.19
Defensins. Natural peptide antibiotics of human neutrophils. J Clin Invest (1985) 8.63
Hepcidin, a urinary antimicrobial peptide synthesized in the liver. J Biol Chem (2000) 8.39
Leukocyte myeloperoxidase deficiency and disseminated candidiasis: the role of myeloperoxidase in resistance to Candida infection. J Clin Invest (1969) 7.61
Diversity of Chlamydia trachomatis major outer membrane protein genes. J Bacteriol (1987) 6.16
Purification and antibacterial activity of antimicrobial peptides of rabbit granulocytes. Infect Immun (1984) 5.30
Lipids, lipoproteins, triglyceride clearance, and cytokines in human immunodeficiency virus infection and the acquired immunodeficiency syndrome. J Clin Endocrinol Metab (1992) 4.25
Severe candidal infections: clinical perspective, immune defense mechanisms, and current concepts of therapy. Ann Intern Med (1978) 4.15
Phagocytosis by human monocytes. Blood (1968) 3.96
Antimicrobial defensin peptides form voltage-dependent ion-permeable channels in planar lipid bilayer membranes. Proc Natl Acad Sci U S A (1990) 3.90
Primary structures of three human neutrophil defensins. J Clin Invest (1985) 3.70
Pneumococcal surface protein A (PspA) is serologically highly variable and is expressed by all clinically important capsular serotypes of Streptococcus pneumoniae. Infect Immun (1990) 3.66
Primary structures of six antimicrobial peptides of rabbit peritoneal neutrophils. J Biol Chem (1985) 3.58
High-resolution mapping of serovar-specific and common antigenic determinants of the major outer membrane protein of Chlamydia trachomatis. J Exp Med (1988) 3.55
Activities of LL-37, a cathelin-associated antimicrobial peptide of human neutrophils. Antimicrob Agents Chemother (1998) 3.45
Widespread expression of beta-defensin hBD-1 in human secretory glands and epithelial cells. FEBS Lett (1996) 3.39
Protegrins: leukocyte antimicrobial peptides that combine features of corticostatic defensins and tachyplesins. FEBS Lett (1993) 3.30
Immigration and the health of Asian and Pacific Islander adults in the United States. Am J Epidemiol (2001) 3.28
Antifungal effects of peroxidase systems. J Bacteriol (1969) 3.24
Microbicidal cationic proteins in rabbit alveolar macrophages: a potential host defense mechanism. Infect Immun (1980) 3.13
Hyperlipidemia and insulin resistance are induced by protease inhibitors independent of changes in body composition in patients with HIV infection. J Acquir Immune Defic Syndr (2000) 3.11
Modulation of Neisseria gonorrhoeae susceptibility to vertebrate antibacterial peptides due to a member of the resistance/nodulation/division efflux pump family. Proc Natl Acad Sci U S A (1998) 3.02
Primary structures of MCP-1 and MCP-2, natural peptide antibiotics of rabbit lung macrophages. J Biol Chem (1983) 3.00
Direct inactivation of viruses by human granulocyte defensins. J Virol (1986) 3.00
Defensins. Eur J Haematol (1990) 2.88
Nonoxidative fungicidal mechanisms of mammalian granulocytes: demonstration of components with candidacidal activity in human, rabbit, and guinea pig leukocytes. Infect Immun (1975) 2.68
NADPH oxidase deficiency in X-linked chronic granulomatous disease. J Clin Invest (1975) 2.62
Defensins. Curr Opin Immunol (1994) 2.55
The gain of three mitochondrial introns identifies liverworts as the earliest land plants. Nature (1998) 2.54
Defensins. Pharmacol Ther (1995) 2.52
Risk factors for graft survival after liver transplantation from donation after cardiac death donors: an analysis of OPTN/UNOS data. Am J Transplant (2006) 2.47
Crystallization of antimicrobial pores in membranes: magainin and protegrin. Biophys J (2000) 2.41
Cryptdins: antimicrobial defensins of the murine small intestine. Infect Immun (1992) 2.39
The crystal structure of flap endonuclease-1 from Methanococcus jannaschii. Nat Struct Biol (1998) 2.37
Reprint request reflexes. Nature (1970) 2.36
Cyclic 3',5'-adenosine monophosphate in the human lukocyte: synthesis, degradation, andeffects n neutrophil candidacidal activity. J Clin Invest (1971) 2.35
Antibacterial activity of microbicidal cationic proteins 1 and 2, natural peptide antibiotics of rabbit lung macrophages. Infect Immun (1983) 2.33
Direct inactivation of viruses by MCP-1 and MCP-2, natural peptide antibiotics from rabbit leukocytes. J Virol (1985) 2.31
Leptospiral outer membrane proteins OmpL1 and LipL41 exhibit synergistic immunoprotection. Infect Immun (1999) 2.30
Immunoproteasomes shape immunodominance hierarchies of antiviral CD8(+) T cells at the levels of T cell repertoire and presentation of viral antigens. J Exp Med (2001) 2.28
The fungicidal mechanisms of human monocytes. I. Evidence for myeloperoxidase-linked and myeloperoxidase-independent candidacidal mechanisms. J Clin Invest (1975) 2.26
Functional aspects of a second mechanism of candidacidal activity by human neutrophils. J Clin Invest (1972) 2.25
Defensins and other endogenous peptide antibiotics of vertebrates. J Leukoc Biol (1995) 2.25
Bactericidal activity of mammalian cathelicidin-derived peptides. Infect Immun (2000) 2.24
Developmental regulation of tandem promoters for the major outer membrane protein gene of Chlamydia trachomatis. J Bacteriol (1988) 2.24
Susceptibility of Chlamydia trachomatis to protegrins and defensins. Infect Immun (1996) 2.16
Effects of cholera enterotoxin on adenosine 3',5'-monophosphate and neutrophil function. Comparison with other compounds which stimulate leukocyte adenyl cyclase. J Clin Invest (1973) 2.16
A function of lung surfactant protein SP-B. Science (1993) 2.15
Dynamic evolution of plant mitochondrial genomes: mobile genes and introns and highly variable mutation rates. Proc Natl Acad Sci U S A (2000) 2.13
Assessment of chlorination by human neutrophils. Nature (1983) 2.12
Concurrent infiltration by CD8+ T cells and CD4+ T cells is a favourable prognostic factor in non-small-cell lung carcinoma. Br J Cancer (2006) 2.09
Activity of rabbit leukocyte peptides against Candida albicans. Infect Immun (1985) 2.05
Development of amphotericin B-resistant Candida tropicalis in a patient with defective leukocyte function. Am J Med Sci (1979) 2.02
Mouse neutrophils lack defensins. Infect Immun (1992) 2.01
In vitro tumor cell cytolysis mediated by peptide defensins of human and rabbit granulocytes. Blood (1986) 2.01
Staphylococcus aureus induces tissue factor expression in cultured human cardiac valve endothelium. J Infect Dis (1988) 1.95
Antimicrobial peptides of vertebrates. Curr Opin Immunol (1998) 1.94
Structural basis for the inactivation of retinoblastoma tumor suppressor by SV40 large T antigen. EMBO J (2001) 1.93
Expression and distribution of leptospiral outer membrane components during renal infection of hamsters. Infect Immun (1999) 1.90
Correlation of binding of rabbit granulocyte peptides to Candida albicans with candidacidal activity. Infect Immun (1985) 1.89
Neutrophil defensins: purification, characterization, and antimicrobial testing. Methods Enzymol (1994) 1.88
Solution structure of protegrin-1, a broad-spectrum antimicrobial peptide from porcine leukocytes. Chem Biol (1996) 1.87
In vitro killing of spores and hyphae of Aspergillus fumigatus and Rhizopus oryzae by rabbit neutrophil cationic peptides and bronchoalveolar macrophages. J Infect Dis (1986) 1.84
Phase and morphology changes in lipid monolayers induced by SP-B protein and its amino-terminal peptide. Science (1996) 1.81
Designer assays for antimicrobial peptides. Disputing the "one-size-fits-all" theory. Methods Mol Biol (1997) 1.79
Fungicidal activity of rabbit alveolar and peritoneal macrophages against Candida albicans. Infect Immun (1980) 1.79
Rubidium release: a rapid and sensitive assay for amphotericin B. J Infect Dis (1976) 1.76
Bactericidal properties of murine intestinal phospholipase A2. J Clin Invest (1995) 1.75
Phagolysosomal pH of human neutrophils. Blood (1984) 1.75
Effects of pH and salinity on the antimicrobial properties of clavanins. Infect Immun (1997) 1.75
Unusual magnetic order in the pseudogap region of the superconductor HgBa2CuO4+delta. Nature (2008) 1.71
Effects of interleukin-1, lipopolysaccharide, and streptococci on procoagulant activity of cultured human cardiac valve endothelial and stromal cells. Infect Immun (1989) 1.71
Susceptibility of Neisseria gonorrhoeae to protegrins. Infect Immun (1996) 1.65
Membrane thinning effect of the beta-sheet antimicrobial protegrin. Biochemistry (2000) 1.64
Mechanism of target cytolysis by peptide defensins. Target cell metabolic activities, possibly involving endocytosis, are crucial for expression of cytotoxicity. J Immunol (1988) 1.64
Structure-based identification of a novel NTPase from Methanococcus jannaschii. Nat Struct Biol (1999) 1.63
Microbicidal/cytotoxic proteins of neutrophils are deficient in two disorders: Chediak-Higashi syndrome and "specific" granule deficiency. J Clin Invest (1988) 1.63
Microbicidal cationic proteins of rabbit alveolar macrophages: amino acid composition and functional attributes. Infect Immun (1981) 1.61
Fungicidal properties of a chymotrypsin-like cationic protein from human neutrophils: adsorption to Candida parapsilosis. Infect Immun (1977) 1.61
Isolation and characterization of human defensin cDNA clones. Proc Natl Acad Sci U S A (1988) 1.61
Defensin-rich dense granules of human neutrophils. Blood (1987) 1.59
Effects of lung surfactant proteins, SP-B and SP-C, and palmitic acid on monolayer stability. Biophys J (2001) 1.58
Arginine-rich cationic proteins of human eosinophil granules: comparison of the constituents of eosinophilic and neutrophilic leukocytes. Lab Invest (1977) 1.57
A new low density lipoprotein receptor related protein, LRP5, is expressed in hepatocytes and adrenal cortex, and recognizes apolipoprotein E. J Biochem (1998) 1.53
Defensins: a family of antimicrobial and cytotoxic peptides. Toxicology (1994) 1.53
The hypertriglyceridemia of acquired immunodeficiency syndrome is associated with an increased prevalence of low density lipoprotein subclass pattern B. J Clin Endocrinol Metab (1993) 1.53
Increased content of microbicidal cationic peptides in rabbit alveolar macrophages elicited by complete Freund adjuvant. Infect Immun (1981) 1.52
Isolation of a prokaryotic metallothionein locus and analysis of transcriptional control by trace metal ions. Mol Microbiol (1993) 1.52
The activation state of p38 mitogen-activated protein kinase determines the efficiency of ATP competition for pyridinylimidazole inhibitor binding. Biochemistry (1998) 1.51
Antimicrobial proteins of murine macrophages. Infect Immun (1993) 1.50
Clinical trial of ranitidine in the treatment of peptic ulcer. Br J Clin Pract (1982) 1.49
Antimicrobial activity of phagocyte granule proteins. Semin Respir Infect (1986) 1.49