Published in J Biol Chem on November 25, 1975
Processing of plasmid DNA during bacterial conjugation. Microbiol Rev (1984) 4.83
Location and nucleotide sequence of the transfer origin of the broad host range plasmid RK2. Proc Natl Acad Sci U S A (1983) 3.61
Nonenteric toxins of Staphylococcus aureus. Microbiol Rev (1979) 2.95
Association of the virD2 protein with the 5' end of T strands in Agrobacterium tumefaciens. J Bacteriol (1988) 2.44
In vitro cleavage of double- and single-stranded DNA by plasmid RSF1010-encoded mobilization proteins. Nucleic Acids Res (1992) 2.09
VirD proteins of Agrobacterium tumefaciens are required for the formation of a covalent DNA--protein complex at the 5' terminus of T-strand molecules. EMBO J (1988) 1.93
Genome-linked protein associated with the 5' termini of bacteriophage phi29 DNA. J Virol (1978) 1.92
Covalent association of protein with replicative form DNA of parvovirus H-1. Proc Natl Acad Sci U S A (1979) 1.92
Genetic organization of plasmid R1162 DNA involved in conjugative mobilization. J Bacteriol (1986) 1.55
Transposon-mediated multiple antibiotic resistance in Acinetobacter strains. Antimicrob Agents Chemother (1982) 1.45
A segment of a plasmid gene required for conjugal transfer encodes a site-specific, single-strand DNA endonuclease and ligase. Nucleic Acids Res (1991) 1.42
Location of two relaxation nick sites in R6K and single sites in pSC101 and RSF1010 close to origins of vegetative replication: implication for conjugal transfer of plasmid deoxyribonucleic acid. J Bacteriol (1980) 1.40
Identification of ColE1 DNA sequences that direct single strand-to-double strand conversion by a phi X174 type mechanism. Proc Natl Acad Sci U S A (1982) 1.31
Biochemical characterization of HgCl2-inducible polypeptides encoded by the mer operon of plasmid R100. J Bacteriol (1982) 1.20
Proteins synthesized in minicells containing plasmid ColE1 and its mutants. J Bacteriol (1978) 1.11
Gene expression in vitro of colicin El plasmid. Nucleic Acids Res (1979) 1.02
Characterization and DNA sequence of the mobilization region of pLV22a from Bacteroides fragilis. J Bacteriol (1995) 0.89
Tales of conjugation and sex pheromones: A plasmid and enterococcal odyssey. Mob Genet Elements (2011) 0.88
Analysis of ColE1 MbeC unveils an extended ribbon-helix-helix family of nicking accessory proteins. J Bacteriol (2008) 0.88
Supercoiled circular DNA-protein complex in Escherichia coli: purification and induced conversion to an opern circular DNA form. Proc Natl Acad Sci U S A (1969) 71.62
Broad host range DNA cloning system for gram-negative bacteria: construction of a gene bank of Rhizobium meliloti. Proc Natl Acad Sci U S A (1980) 45.02
Replication of an origin-containing derivative of plasmid RK2 dependent on a plasmid function provided in trans. Proc Natl Acad Sci U S A (1979) 44.75
Plasmid ColEl as a molecular vehicle for cloning and amplification of DNA. Proc Natl Acad Sci U S A (1974) 32.46
Stimulation by cyclic adenosine monophosphate of plasmid deoxyribonucleic acid replication and catabolite repression of the plasmid deoxyribonucleic acid-protein relaxation complex. J Bacteriol (1973) 30.43
Firefly luciferase gene: structure and expression in mammalian cells. Mol Cell Biol (1987) 26.70
Properties of a supercoiled deoxyribonucleic acid-protein relaxation complex and strand specificity of the relaxation event. Biochemistry (1970) 26.22
Circular DNA forms of colicinogenic factors E1, E2 and E3 from Escherichia coli. J Mol Biol (1968) 23.73
Characterization of multiple circular DNA forms of colicinogenic factor E-1 from Proteus mirabilis. Biochemistry (1968) 14.82
Plasmid cloning vehicles derived from plasmids ColE1, F, R6K, and RK2. Methods Enzymol (1979) 13.61
Plasmids related to the broad host range vector, pRK290, useful for gene cloning and for monitoring gene expression. Plasmid (1985) 11.74
Evidence for circular DNA forms of a bacterial plasmid. Proc Natl Acad Sci U S A (1967) 10.45
Circular DNA. Annu Rev Biochem (1971) 9.75
Effect of growth conditions on the formation of the relaxation complex of supercoiled ColE1 deoxyribonucleic acid and protein in Escherichia coli. J Bacteriol (1972) 9.50
DNA polymerase as a requirement for the maintenance of the bacterial plasmid colicinogenic factor E1. Biochem Biophys Res Commun (1970) 8.73
Circular DNA forms of a bacterial sex factor. Proc Natl Acad Sci U S A (1967) 8.55
Trans-complementation-dependent replication of a low molecular weight origin fragment from plasmid R6K. Cell (1978) 8.28
Characterization of a mini-ColC1 plasmid. J Bacteriol (1976) 7.20
Effect of Rec mutations on the activity of colicinogenic factors. J Bacteriol (1967) 7.19
Replication of a bacterial plasmid and an episome in Escherichia coli. Biochemistry (1970) 7.19
Unidirectional replication of the P-group plasmid RK2. Biochim Biophys Acta (1977) 6.17
Transient and stable expression of the firefly luciferase gene in plant cells and transgenic plants. Science (1986) 5.97
Heme biosynthesis in Rhizobium. Identification of a cloned gene coding for delta-aminolevulinic acid synthetase from Rhizobium meliloti. J Biol Chem (1982) 5.80
Method for the isolation of the replication region of a bacterial replicon: construction of a mini-F'kn plasmid. J Bacteriol (1976) 5.75
Purification and characterization of colicin E2 and colicin E3. J Biol Chem (1967) 5.74
A catenated DNA molecule as an intermediate in the replication of the resistance transfer factor R6K in Escherichia coli. Biochem Biophys Res Commun (1973) 5.47
Regions of broad-host-range plasmid RK2 which are essential for replication and maintenance. J Bacteriol (1980) 5.45
Temperature-sensitive mutants for the replication of plasmids in Escherichia coli: requirement for deoxyribonucleic acid polymerase I in the replication of the plasmid ColE 1 . J Bacteriol (1973) 5.24
Gene cloning and containment properties of plasmid Col E1 and its derivatives. Science (1977) 5.21
Comparative study of the events associated with colicin induction. J Bacteriol (1967) 5.14
Strand-specific supercoiled DNA-protein relaxation complexes: comparison of the complexes of bacterial plasmids ColE1 and ColE2. Proc Natl Acad Sci U S A (1971) 4.76
Suppression of Co1E1 replication properties by the Inc P-1 plasmid RK2 in hybrid plasmids constructed in vitro. J Mol Biol (1979) 4.69
The DNA-protein relaxation complex of the plasmid RK2: location of the site-specific nick in the region of the proposed origin of transfer. Mol Gen Genet (1979) 4.48
Isolation of supercoiled colicinogenic factor E 1 DNA sensitive to ribonuclease and alkali. Proc Natl Acad Sci U S A (1972) 4.46
A haemoprotein with kinase activity encoded by the oxygen sensor of Rhizobium meliloti. Nature (1991) 4.45
Generation in vitro of deletions in the broad host range plasmid RK2 using phage Mu insertions and a restriction endonuclease. Gene (1976) 4.35
Physical and genetic studies with restriction endonucleases on the broad host-range plasmid RK2. Mol Gen Genet (1977) 4.28
Purification and characterization of colicin E1. J Biol Chem (1971) 4.27
Unidirectional replication of plasmid ColE1 DNA. Nature (1974) 4.27
Complete nucleotide sequence of Birmingham IncP alpha plasmids. Compilation and comparative analysis. J Mol Biol (1994) 4.23
Generation of higher multiple circular DNA forms in bacteria. Proc Natl Acad Sci U S A (1968) 3.98
Regions of broad-host-range plasmid RK2 involved in replication and stable maintenance in nine species of gram-negative bacteria. J Bacteriol (1985) 3.93
Rhizobium meliloti genes required for nodule development are related to chromosomal virulence genes in Agrobacterium tumefaciens. Proc Natl Acad Sci U S A (1986) 3.38
Cloning of firefly luciferase cDNA and the expression of active luciferase in Escherichia coli. Proc Natl Acad Sci U S A (1985) 3.35
Structural relationships among Rhizobium meliloti symbiotic promoters. Cell (1983) 3.23
Construction of plasmid cloning vehicles that promote gene expression from the bacteriophage lambda pL promoter. Gene (1979) 3.00
Humoral immune response in human syphilis to polypeptides of Treponema pallidum. J Immunol (1982) 2.99
Molecular vehicle properties of the broad host range plasmid RK2. Science (1975) 2.97
Isolation and characterization of the recA gene of Rhizobium meliloti. J Bacteriol (1983) 2.89
Strand and site specificity of the relaxation event for the relaxation complex of the antibiotic resistance plasmid R6K. Biochemistry (1974) 2.81
Use of the lambda phage promoter PL to promote gene expression in hybrid plasmid cloning vehicles. Methods Enzymol (1979) 2.74
A 9.0-kilobase-pair circular plasmid of Borrelia burgdorferi encodes an exported protein: evidence for expression only during infection. Infect Immun (1994) 2.74
Clustering of nitrogen fixation (nif) genes in Rhizobium meliloti. J Bacteriol (1982) 2.66
F 1 sex factor of Escherichia coli. Size and purification in the form of a strand-specific relaxation complex of supercoiled deoxyribonucleic acid and protein. Biochemistry (1971) 2.63
Purification of Treponema pallidum, Nichols strain, by Percoll density gradient centrifugation. Sex Transm Dis (1985) 2.63
The FixL protein of Rhizobium meliloti can be separated into a heme-binding oxygen-sensing domain and a functional C-terminal kinase domain. Proc Natl Acad Sci U S A (1992) 2.51
Demonstration of rare protein in the outer membrane of Treponema pallidum subsp. pallidum by freeze-fracture analysis. J Bacteriol (1989) 2.46
The ndvA gene product of Rhizobium meliloti is required for beta-(1----2)glucan production and has homology to the ATP-binding export protein HlyB. J Bacteriol (1988) 2.45
Plasmid determined resistance to antibiotics: molecular properties of R factors. Annu Rev Microbiol (1973) 2.39
Nucleotide sequence of the region of the origin of replication of the broad host range plasmid RK2. Mol Gen Genet (1981) 2.38
Treponema pallidum invades intercellular junctions of endothelial cell monolayers. Proc Natl Acad Sci U S A (1988) 2.37
Plasmid R6K DNA replication. I. Complete nucleotide sequence of an autonomously replicating segment. J Mol Biol (1982) 2.30
Changes in the surface of Leptospira interrogans serovar grippotyphosa during in vitro cultivation. Infect Immun (1991) 2.29
Molecular cloning and sequence analysis of the gene encoding OmpL1, a transmembrane outer membrane protein of pathogenic Leptospira spp. J Bacteriol (1993) 2.28
Genetic characterization of the stabilizing functions of a region of broad-host-range plasmid RK2. J Bacteriol (1990) 2.26
Relaxation complexes of plasmids ColE1 and ColE2: unique site of the nick in the open circular DNA of the relaxed complexes. Proc Natl Acad Sci U S A (1974) 2.22
Chromogenic immunodetection of human serum albumin and alpha-L-fucosidase clones in a human hepatoma cDNA expression library. DNA (1984) 2.15
Plasmid R6K DNA replication. III. Regulatory properties of the pi initiation protein. J Mol Biol (1982) 2.12
Serologic analysis of first-episode nonprimary genital herpes simplex virus infection. Presence of type 2 antibody in acute serum samples. Am J Med (1984) 2.05
Selective release of the Treponema pallidum outer membrane and associated polypeptides with Triton X-114. J Bacteriol (1988) 2.05
Expression of Treponema pallidum antigens in Escherichia coli. Science (1982) 2.02
Temperature-sensitive mutants for the replication of plasmids in Escherichia coli. I. Isolation and specificity of host and plasmid mutations. Genetics (1973) 2.01
Interaction between colicinogenic factor V and the integrated F factor in an Hfr strain of Escherichia coli. J Bacteriol (1965) 2.01
Heterogeneous circular DNA elements in vegetative cultures of Bacillus megaterium. Proc Natl Acad Sci U S A (1969) 1.99
Humoral immune response in experimental syphilis to polypeptides of Treponema pallidum. J Immunol (1983) 1.97
Bidirectional replication of plasmid R6K DNA in Escherichia coli; correspondence between origin of replication and position of single-strand break in relaxed complex. Proc Natl Acad Sci U S A (1975) 1.95
Nucleotide sequence of the region of an origin of replication of the antibiotic resistance plasmid R6K. Proc Natl Acad Sci U S A (1979) 1.95
Deletion analysis of Rhizobium meliloti symbiotic promoters. EMBO J (1985) 1.84
Antigenic and structural characterization of Treponema pallidum (Nichols strain) endoflagella. Infect Immun (1988) 1.83
Requirement of a plasmid-encoded protein for replication in vitro of plasmid R6K. Proc Natl Acad Sci U S A (1978) 1.83
Relaxation complexes of poasmid DNA and protein. III. Association of protein with the 5' terminus of the broken DNA strand in the relaxed complex of plasmid ColE1. J Biol Chem (1975) 1.82
Purification and characterization of a cloned protease-resistant Treponema pallidum-specific antigen. Infect Immun (1984) 1.80
Construction of plasmid R6K derivatives in vitro: characterization of the R6K replication region. Plasmid (1978) 1.79
Negative control of plasmid R6K replication: possible role of intermolecular coupling of replication origins. Proc Natl Acad Sci U S A (1989) 1.77
Complement activation limits the rate of in vitro treponemicidal activity and correlates with antibody-mediated aggregation of Treponema pallidum rare outer membrane protein. J Immunol (1990) 1.76
Bidirection replication from a unique origin in a mini-F plasmid. Proc Natl Acad Sci U S A (1977) 1.70
Common regulatory elements control symbiotic and microaerobic induction of nifA in Rhizobium meliloti. Proc Natl Acad Sci U S A (1988) 1.69
Evidence for the existence of the colicinogenic factors E2 and E3 as supercoiled circular DNA-protein relaxation complexes. Biochem Biophys Res Commun (1970) 1.68
Isolation of the outer membranes from Treponema pallidum and Treponema vincentii. J Bacteriol (1994) 1.67
Relaxation complexes of plasmid DNA and protein. I. Strand-specific association of protein and DNA in the relaxed complexes of plasmids ColE1 and ColE2. J Biol Chem (1975) 1.66
The Oms66 (p66) protein is a Borrelia burgdorferi porin. Infect Immun (1997) 1.65
Binding of purified wild-type and mutant pi initiation proteins to a replication origin region of plasmid R6K. J Mol Biol (1986) 1.65
Virulent strain associated outer membrane proteins of Borrelia burgdorferi. J Clin Invest (1995) 1.64
Multicopy plasmids are clustered and localized in Escherichia coli. Proc Natl Acad Sci U S A (2001) 1.64