Characterization of double-strand break-induced recombination: homology requirements and single-stranded DNA formation.

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Published in Mol Cell Biol on February 01, 1992

Authors

N Sugawara1, J E Haber

Author Affiliations

1: Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, Massachusetts 02254-9110.

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Identification of autonomously replicating circular subtelomeric Y' elements in Saccharomyces cerevisiae. Mol Cell Biol (1985) 1.21

Mcm1 regulates donor preference controlled by the recombination enhancer in Saccharomyces mating-type switching. Genes Dev (1998) 1.21

Dominant lethal mutations in the plasma membrane H(+)-ATPase gene of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1994) 1.20

Arrest, adaptation, and recovery following a chromosome double-strand break in Saccharomyces cerevisiae. Cold Spring Harb Symp Quant Biol (2000) 1.19

Meiotic recombination initiated by a double-strand break in rad50 delta yeast cells otherwise unable to initiate meiotic recombination. Genetics (1996) 1.19

Cell cycle-dependent induction of mutations along a yeast chromosome. Proc Natl Acad Sci U S A (1975) 1.19

Illegal transposition of mating-type genes in yeast. Cell (1980) 1.19

HO endonuclease-induced recombination in yeast meiosis resembles Spo11-induced events. Proc Natl Acad Sci U S A (2000) 1.18

MOP2 (SLA2) affects the abundance of the plasma membrane H(+)-ATPase of Saccharomyces cerevisiae. J Biol Chem (1995) 1.18

Nonrecombinant meiosis I nondisjunction in Saccharomyces cerevisiae induced by tRNA ochre suppressors. Genetics (1989) 1.17

crl mutants of Saccharomyces cerevisiae resemble both mutants affecting general control of amino acid biosynthesis and omnipotent translational suppressor mutants. Genetics (1988) 1.17

New cytoplasmic genetic element that controls 20S RNA synthesis during sporulation in yeast. J Bacteriol (1978) 1.15

Regulation of sporulation in yeast. Curr Top Dev Biol (1972) 1.13

Sporulation and rna2 lower ribosomal protein mRNA levels by different mechanisms in Saccharomyces cerevisiae. Mol Cell Biol (1982) 1.11