Two different types of double-strand breaks in Saccharomyces cerevisiae are repaired by similar RAD52-independent, nonhomologous recombination events.

PubWeight™: 3.40‹?› | Rank: Top 1%

🔗 View Article (PMC 358484)

Published in Mol Cell Biol on February 01, 1994

Authors

K M Kramer1, J A Brock, K Bloom, J K Moore, J E Haber

Author Affiliations

1: Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, Massachusetts 02254-9110.

Articles citing this

Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae. Microbiol Mol Biol Rev (1999) 19.25

Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae. Mol Cell Biol (1996) 7.33

Introduction of double-strand breaks into the genome of mouse cells by expression of a rare-cutting endonuclease. Mol Cell Biol (1994) 6.08

Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing. EMBO J (1998) 5.79

Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathways. EMBO J (1996) 4.58

Double-strand break repair in the absence of RAD51 in yeast: a possible role for break-induced DNA replication. Proc Natl Acad Sci U S A (1996) 4.49

Identification of a Saccharomyces cerevisiae Ku80 homologue: roles in DNA double strand break rejoining and in telomeric maintenance. Nucleic Acids Res (1996) 4.37

Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex. Genes Dev (1999) 4.08

Ku80 is required for immunoglobulin isotype switching. EMBO J (1998) 3.67

Mutations in two Ku homologs define a DNA end-joining repair pathway in Saccharomyces cerevisiae. Mol Cell Biol (1996) 3.57

RAD50 and RAD51 define two pathways that collaborate to maintain telomeres in the absence of telomerase. Genetics (1999) 3.55

Repair of site-specific double-strand breaks in a mammalian chromosome by homologous and illegitimate recombination. Mol Cell Biol (1997) 3.07

DNA length dependence of the single-strand annealing pathway and the role of Saccharomyces cerevisiae RAD59 in double-strand break repair. Mol Cell Biol (2000) 2.95

Distinct roles of two separable in vitro activities of yeast Mre11 in mitotic and meiotic recombination. EMBO J (1998) 2.94

High-resolution profiling of gammaH2AX around DNA double strand breaks in the mammalian genome. EMBO J (2010) 2.89

The Saccharomyces cerevisiae Ku autoantigen homologue affects radiosensitivity only in the absence of homologous recombination. Genetics (1996) 2.79

A newly identified DNA ligase of Saccharomyces cerevisiae involved in RAD52-independent repair of DNA double-strand breaks. Genes Dev (1997) 2.61

Conditional gene targeted deletion by Cre recombinase demonstrates the requirement for the double-strand break repair Mre11 protein in murine embryonic stem cells. Nucleic Acids Res (1997) 2.58

Chromosome break-induced DNA replication leads to nonreciprocal translocations and telomere capture. Genetics (1998) 2.55

Break-induced replication: a review and an example in budding yeast. Proc Natl Acad Sci U S A (2001) 2.31

DNA double-strand break repair in cell-free extracts from Ku80-deficient cells: implications for Ku serving as an alignment factor in non-homologous DNA end joining. Nucleic Acids Res (2000) 2.29

Defects in XRCC4 and KU80 differentially affect the joining of distal nonhomologous ends. Proc Natl Acad Sci U S A (2007) 2.27

Replication slippage between distant short repeats in Saccharomyces cerevisiae depends on the direction of replication and the RAD50 and RAD52 genes. Mol Cell Biol (1995) 2.21

Human Rad50 is physically associated with human Mre11: identification of a conserved multiprotein complex implicated in recombinational DNA repair. Mol Cell Biol (1996) 2.21

Repair of a specific double-strand break generated within a mammalian chromosome by yeast endonuclease I-SceI. Nucleic Acids Res (1994) 2.17

End-joining, translocations and cancer. Nat Rev Cancer (2013) 2.13

A mechanistic basis for Mre11-directed DNA joining at microhomologies. Proc Natl Acad Sci U S A (2000) 2.05

Mating-type genes and MAT switching in Saccharomyces cerevisiae. Genetics (2012) 1.96

Illegitimate recombination induced by DNA double-strand breaks in a mammalian chromosome. Mol Cell Biol (1994) 1.96

Repair of intermediate structures produced at DNA interstrand cross-links in Saccharomyces cerevisiae. Mol Cell Biol (2000) 1.71

Homology search and choice of homologous partner during mitotic recombination. Mol Cell Biol (1999) 1.68

Capture of DNA sequences at double-strand breaks in mammalian chromosomes. Genetics (2001) 1.66

Sources of DNA double-strand breaks and models of recombinational DNA repair. Cold Spring Harb Perspect Biol (2014) 1.65

Ku-dependent and Ku-independent end-joining pathways lead to chromosomal rearrangements during double-strand break repair in Saccharomyces cerevisiae. Genetics (2003) 1.64

Effects of mutations of RAD50, RAD51, RAD52, and related genes on illegitimate recombination in Saccharomyces cerevisiae. Genetics (1996) 1.52

Rejoining of DNA double-strand breaks as a function of overhang length. Mol Cell Biol (2005) 1.52

Multiple pathways for repair of DNA double-strand breaks in mammalian chromosomes. Mol Cell Biol (1999) 1.47

Genome-wide amplifications caused by chromosomal rearrangements play a major role in the adaptive evolution of natural yeast. Genetics (2003) 1.47

Mechanism of MAT alpha donor preference during mating-type switching of Saccharomyces cerevisiae. Mol Cell Biol (1996) 1.41

DNA-binding and strand-annealing activities of human Mre11: implications for its roles in DNA double-strand break repair pathways. Nucleic Acids Res (2001) 1.38

Recombination-dependent deletion formation in mammalian cells deficient in the nucleotide excision repair gene ERCC1. Proc Natl Acad Sci U S A (1997) 1.38

Homologous recombinational repair of double-strand breaks in yeast is enhanced by MAT heterozygosity through yKU-dependent and -independent mechanisms. Genetics (2001) 1.33

Hdf1, a yeast Ku-protein homologue, is involved in illegitimate recombination, but not in homologous recombination. Nucleic Acids Res (1996) 1.29

Non-homologous end joining often uses microhomology: implications for alternative end joining. DNA Repair (Amst) (2014) 1.24

Saccharomyces cerevisiae as a model system to define the chromosomal instability phenotype. Mol Cell Biol (2005) 1.24

The path of DNA in the kinetochore. Curr Biol (2006) 1.22

The Saccharomyces cerevisiae chromatin remodeler Fun30 regulates DNA end resection and checkpoint deactivation. Mol Cell Biol (2012) 1.22

Requirement for end-joining and checkpoint functions, but not RAD52-mediated recombination, after EcoRI endonuclease cleavage of Saccharomyces cerevisiae DNA. Mol Cell Biol (1998) 1.21

Microhomology-dependent end joining and repair of transposon-induced DNA hairpins by host factors in Saccharomyces cerevisiae. Mol Cell Biol (2004) 1.16

The RAD5 gene product is involved in the avoidance of non-homologous end-joining of DNA double strand breaks in the yeast Saccharomyces cerevisiae. Nucleic Acids Res (1997) 1.15

Alternative end-joining mechanisms: a historical perspective. Front Genet (2013) 1.13

Dicentric chromosome stretching during anaphase reveals roles of Sir2/Ku in chromatin compaction in budding yeast. Mol Biol Cell (2001) 1.10

Involvement of very short DNA tandem repeats and the influence of the RAD52 gene on the occurrence of deletions in Saccharomyces cerevisiae. Genetics (2000) 1.04

Reciprocal translocations in Saccharomyces cerevisiae formed by nonhomologous end joining. Genetics (2004) 1.03

Mutations in the Saccharomyces cerevisiae CDC1 gene affect double-strand-break-induced intrachromosomal recombination. Mol Cell Biol (1994) 1.03

The essential helicase gene RAD3 suppresses short-sequence recombination in Saccharomyces cerevisiae. Mol Cell Biol (1995) 1.02

Ionizing radiation and restriction enzymes induce microhomology-mediated illegitimate recombination in Saccharomyces cerevisiae. Nucleic Acids Res (2007) 1.01

Polymerases in nonhomologous end joining: building a bridge over broken chromosomes. Antioxid Redox Signal (2010) 1.00

Expression of Mycobacterium tuberculosis Ku and Ligase D in Escherichia coli results in RecA and RecB-independent DNA end-joining at regions of microhomology. DNA Repair (Amst) (2007) 0.98

Stabilization of dicentric translocations through secondary rearrangements mediated by multiple mechanisms in S. cerevisiae. PLoS One (2009) 0.98

Nonhomologous end joining during restriction enzyme-mediated DNA integration in Saccharomyces cerevisiae. Mol Cell Biol (1998) 0.98

Radiation-induced chromosome aberrations in Saccharomyces cerevisiae: influence of DNA repair pathways. Genetics (1998) 0.95

Base damage immediately upstream from double-strand break ends is a more severe impediment to nonhomologous end joining than blocked 3'-termini. Radiat Res (2011) 0.94

Induction of Ty recombination in yeast by cDNA and transcription: role of the RAD1 and RAD52 genes. Genetics (1996) 0.94

Capture of extranuclear DNA at fission yeast double-strand breaks. Genetics (2005) 0.94

The liaison of isotype class switch and mismatch repair: an illegitimate affair. J Exp Med (1999) 0.93

Expression of the adenovirus E4 34k oncoprotein inhibits repair of double strand breaks in the cellular genome of a 293-based inducible cell line. Nucleic Acids Res (2004) 0.93

Dicentric breakage at telomere fusions. Genes Dev (2010) 0.92

Expansion and contraction of the DUP240 multigene family in Saccharomyces cerevisiae populations. Genetics (2004) 0.91

Cytokinesis breaks dicentric chromosomes preferentially at pericentromeric regions and telomere fusions. Genes Dev (2015) 0.89

A Flp-nick system to study repair of a single protein-bound nick in vivo. Nat Methods (2009) 0.89

DNA double-strand breaks and telomeres play important roles in trypanosoma brucei antigenic variation. Eukaryot Cell (2015) 0.87

Knockout of the DNA ligase IV homolog gene in the sphingoid base producing yeast Pichia ciferrii significantly increases gene targeting efficiency. Curr Genet (2009) 0.86

Nonhomologous DNA end joining of synthetic hairpin substrates in Xenopus laevis egg extracts. Nucleic Acids Res (1994) 0.85

Multiple pathways promote short-sequence recombination in Saccharomyces cerevisiae. Mol Cell Biol (2002) 0.84

The contribution of alu elements to mutagenic DNA double-strand break repair. PLoS Genet (2015) 0.84

DNA damage-inducible and RAD52-independent repair of DNA double-strand breaks in Saccharomyces cerevisiae. Genetics (2000) 0.83

Nonrandom distribution of interhomolog recombination events induced by breakage of a dicentric chromosome in Saccharomyces cerevisiae. Genetics (2013) 0.83

A specific N-terminal extension of the 8 kDa domain is required for DNA end-bridging by human Polμ and Polλ. Nucleic Acids Res (2013) 0.83

A novel selection system for chromosome translocations in Saccharomyces cerevisiae. Genetics (2002) 0.82

Ionizing radiation induces microhomology-mediated end joining in trans in yeast and mammalian cells. Radiat Res (2009) 0.81

Chromosome breakage and repair. Genetics (2006) 0.81

Decision-making during NHEJ: a network of interactions in human Polμ implicated in substrate recognition and end-bridging. Nucleic Acids Res (2014) 0.80

Transposition-mediated DNA re-replication in maize. Elife (2014) 0.79

Role of budding yeast Rad18 in repair of HO-induced double-strand breaks. DNA Repair (Amst) (2008) 0.77

Requirement of POL3 and POL4 on non-homologous and microhomology-mediated end joining in rad50/xrs2 mutants of Saccharomyces cerevisiae. Mutagenesis (2015) 0.77

Rad1, rad10 and rad52 mutations reduce the increase of microhomology length during radiation-induced microhomology-mediated illegitimate recombination in saccharomyces cerevisiae. Radiat Res (2009) 0.77

Effect of rad50 mutation on illegitimate recombination in Saccharomyces cerevisiae. Mol Genet Genomics (2011) 0.76

Consider the workhorse: Nonhomologous end-joining in budding yeast. Biochem Cell Biol (2016) 0.75

Pathways and Mechanisms that Prevent Genome Instability in Saccharomyces cerevisiae. Genetics (2017) 0.75

DEG1, encoding the tRNA:pseudouridine synthase Pus3p, impacts HOT1-stimulated recombination in Saccharomyces cerevisiae. Mol Genet Genomics (2005) 0.75

Articles cited by this

Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. Science (1988) 220.77

High efficiency transformation of intact yeast cells using single stranded nucleic acids as a carrier. Curr Genet (1989) 31.80

The double-strand-break repair model for recombination. Cell (1983) 31.21

Yeast transformation: a model system for the study of recombination. Proc Natl Acad Sci U S A (1981) 26.54

Nucleotide sequence comparisons and functional analysis of yeast centromere DNAs. Cell (1982) 7.01

The repair of double-strand breaks in the nuclear DNA of Saccharomyces cerevisiae and its genetic control. Mol Gen Genet (1976) 6.89

Extensive 3'-overhanging, single-stranded DNA associated with the meiosis-specific double-strand breaks at the ARG4 recombination initiation site. Cell (1991) 6.80

The RAD52 gene is required for homothallic interconversion of mating types and spontaneous mitotic recombination in yeast. Proc Natl Acad Sci U S A (1980) 6.50

Intermediates of recombination during mating type switching in Saccharomyces cerevisiae. EMBO J (1990) 5.94

Characterization of double-strand break-induced recombination: homology requirements and single-stranded DNA formation. Mol Cell Biol (1992) 5.71

A regulatory hierarchy for cell specialization in yeast. Nature (1989) 5.68

Yeast centromere DNA is in a unique and highly ordered structure in chromosomes and small circular minichromosomes. Cell (1982) 5.49

Nonhomologous recombination in mammalian cells: role for short sequence homologies in the joining reaction. Mol Cell Biol (1986) 5.25

Removal of nonhomologous DNA ends in double-strand break recombination: the role of the yeast ultraviolet repair gene RAD1. Science (1992) 5.08

Two alternative pathways of double-strand break repair that are kinetically separable and independently modulated. Mol Cell Biol (1992) 4.97

Homothallic mating type switching generates lethal chromosome breaks in rad52 strains of Saccharomyces cerevisiae. Mol Cell Biol (1981) 4.41

Mechanisms of nonhomologous recombination in mammalian cells. Mol Cell Biol (1985) 4.20

Reexamination of gene targeting frequency as a function of the extent of homology between the targeting vector and the target locus. Mol Cell Biol (1992) 4.19

Integration of DNA fragments by illegitimate recombination in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1991) 4.18

Molecular analysis of a cell lineage. Nature (1983) 4.08

Efficient repair of HO-induced chromosomal breaks in Saccharomyces cerevisiae by recombination between flanking homologous sequences. Mol Cell Biol (1988) 4.02

Gene deletions causing human genetic disease: mechanisms of mutagenesis and the role of the local DNA sequence environment. Hum Genet (1991) 3.48

A unique pathway of double-strand break repair operates in tandemly repeated genes. Mol Cell Biol (1991) 3.36

Gene conversion of deletions in the his4 region of yeast. Genetics (1974) 3.26

Directionality and regulation of cassette substitution in yeast. Cold Spring Harb Symp Quant Biol (1984) 3.23

Double-strand breaks stimulate alternative mechanisms of recombination repair. J Mol Biol (1989) 3.23

The structure and evolution of subtelomeric Y' repeats in Saccharomyces cerevisiae. Genetics (1992) 2.96

Site-specific recombination determined by I-SceI, a mitochondrial group I intron-encoded endonuclease expressed in the yeast nucleus. Genetics (1992) 2.92

Role of conserved sequence elements in yeast centromere DNA. EMBO J (1985) 2.75

Single base-pair mutations in centromere element III cause aberrant chromosome segregation in Saccharomyces cerevisiae. Mol Cell Biol (1986) 2.65

Involvement of double-strand chromosomal breaks for mating-type switching in Saccharomyces cerevisiae. Cold Spring Harb Symp Quant Biol (1984) 2.64

A novel pathway of DNA end-to-end joining. Cell (1990) 2.61

Effect of limited homology on gene conversion in a Saccharomyces cerevisiae plasmid recombination system. Mol Cell Biol (1988) 2.37

Healing of broken linear dicentric chromosomes in yeast. Genetics (1984) 2.35

Physical monitoring of mating type switching in Saccharomyces cerevisiae. Mol Cell Biol (1988) 2.33

Joining of nonhomologous DNA double strand breaks in vitro. Nucleic Acids Res (1988) 2.29

The cyc1-11 mutation in yeast reverts by recombination with a nonallelic gene: composite genes determining the iso-cytochromes c. Proc Natl Acad Sci U S A (1981) 2.22

Recombination between similar but not identical DNA sequences during yeast transformation occurs within short stretches of identity. Cell (1992) 2.21

A 125-base-pair CEN6 DNA fragment is sufficient for complete meiotic and mitotic centromere functions in Saccharomyces cerevisiae. Mol Cell Biol (1989) 2.14

Transformation of Saccharomyces cerevisiae with nonhomologous DNA: illegitimate integration of transforming DNA into yeast chromosomes and in vivo ligation of transforming DNA to mitochondrial DNA sequences. Mol Cell Biol (1993) 2.12

Deletions and single base pair changes in the yeast mating type locus that prevent homothallic mating type conversions. Proc Natl Acad Sci U S A (1983) 2.09

A new gene affecting the efficiency of mating-type interconversions in homothallic strains of Saccharomyces cerevisiae. Genetics (1977) 2.08

Mating-type gene switching in Saccharomyces cerevisiae. Trends Genet (1992) 2.03

A mechanism for deletion formation in DNA by human cell extracts: the involvement of short sequence repeats. Nucleic Acids Res (1992) 2.03

Exploring the pathways of homologous recombination. Curr Opin Cell Biol (1992) 2.02

Heteroduplex formation and mismatch repair of the "stuck" mutation during mating-type switching in Saccharomyces cerevisiae. Mol Cell Biol (1991) 1.98

Polymerase chain reaction strategy. Annu Rev Biochem (1992) 1.88

Chromatin structure of altered yeast centromeres. Proc Natl Acad Sci U S A (1988) 1.74

A genetic analysis of dicentric minichromosomes in Saccharomyces cerevisiae. Cell (1987) 1.70

In vivo analysis of the Saccharomyces cerevisiae centromere CDEIII sequence: requirements for mitotic chromosome segregation. Mol Cell Biol (1991) 1.65

Acquisition and processing of a conditional dicentric chromosome in Saccharomyces cerevisiae. Mol Cell Biol (1989) 1.61

Yeast centromeres: structure and function. Cell (1984) 1.59

The determination of mother cell-specific mating type switching in yeast by a specific regulator of HO transcription. EMBO J (1987) 1.42

DNA sequence analysis of X-ray-induced deletions at the white locus of Drosophila melanogaster. Mutat Res (1988) 1.36

Deletion and rearrangement of plasmid DNA during transformation of Escherichia coli with linear plasmid molecules. Nucleic Acids Res (1986) 1.30

Mechanism of intramolecular recyclization and deletion formation following transformation of Escherichia coli with linearized plasmid DNA. Nucleic Acids Res (1986) 1.26

Resolution of dicentric chromosomes by Ty-mediated recombination in yeast. Genetics (1985) 1.20

Mitotic recombination in yeast. Trends Genet (1988) 1.18

Noncomplementary DNA double-strand-break rejoining in bacterial and human cells. Nucleic Acids Res (1993) 1.16

Stabilization of dicentric chromosomes in Saccharomyces cerevisiae by telomere addition to broken ends or by centromere deletion. EMBO J (1989) 1.11

Genetic dissection of centromere function. Mol Cell Biol (1993) 1.00

Formation of inverted dimer plasmids after transformation of yeast with linearized plasmid DNA. Cold Spring Harb Symp Quant Biol (1984) 0.93

Articles by these authors

Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae. Microbiol Mol Biol Rev (1999) 19.25

Saccharomyces Ku70, mre11/rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage. Cell (1998) 8.31

Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae. Mol Cell Biol (1996) 7.33

Lethal disruption of the yeast actin gene by integrative DNA transformation. Science (1982) 6.88

Intermediates of recombination during mating type switching in Saccharomyces cerevisiae. EMBO J (1990) 5.94

Disruption of mitotic spindle orientation in a yeast dynein mutant. Proc Natl Acad Sci U S A (1993) 5.94

Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A. Nature (1993) 5.81

Characterization of double-strand break-induced recombination: homology requirements and single-stranded DNA formation. Mol Cell Biol (1992) 5.71

Spindle dynamics and cell cycle regulation of dynein in the budding yeast, Saccharomyces cerevisiae. J Cell Biol (1995) 5.27

Removal of nonhomologous DNA ends in double-strand break recombination: the role of the yeast ultraviolet repair gene RAD1. Science (1992) 5.08

Two alternative pathways of double-strand break repair that are kinetically separable and independently modulated. Mol Cell Biol (1992) 4.97

Meiotic gene conversion and crossing over between dispersed homologous sequences occurs frequently in Saccharomyces cerevisiae. Genetics (1987) 4.94

Double-strand break repair in the absence of RAD51 in yeast: a possible role for break-induced DNA replication. Proc Natl Acad Sci U S A (1996) 4.49

Homothallic mating type switching generates lethal chromosome breaks in rad52 strains of Saccharomyces cerevisiae. Mol Cell Biol (1981) 4.41

Genetic requirements for the single-strand annealing pathway of double-strand break repair in Saccharomyces cerevisiae. Genetics (1996) 4.33

Efficient repair of HO-induced chromosomal breaks in Saccharomyces cerevisiae by recombination between flanking homologous sequences. Mol Cell Biol (1988) 4.02

Meiotic recombination in yeast: alteration by multiple heterozygosities. Science (1987) 3.93

Regulation of Saccharomyces Rad53 checkpoint kinase during adaptation from DNA damage-induced G2/M arrest. Mol Cell (2001) 3.74

Astral microtubule dynamics in yeast: a microtubule-based searching mechanism for spindle orientation and nuclear migration into the bud. J Cell Biol (1997) 3.65

Telomere maintenance is dependent on activities required for end repair of double-strand breaks. Curr Biol (1998) 3.63

RAD50 and RAD51 define two pathways that collaborate to maintain telomeres in the absence of telomerase. Genetics (1999) 3.55

Budding yeast chromosome structure and dynamics during mitosis. J Cell Biol (2001) 3.39

Analysis of meiosis-defective mutations in yeast by physical monitoring of recombination. Genetics (1986) 3.38

Mutations in XRS2 and RAD50 delay but do not prevent mating-type switching in Saccharomyces cerevisiae. Mol Cell Biol (1994) 3.34

Role of Saccharomyces cerevisiae Msh2 and Msh3 repair proteins in double-strand break-induced recombination. Proc Natl Acad Sci U S A (1997) 3.29

Two pathways for removal of nonhomologous DNA ends during double-strand break repair in Saccharomyces cerevisiae. Mol Cell Biol (1997) 3.27

An evaluation of the relatedness of proteins based on comparison of amino acid sequences. J Mol Biol (1970) 3.26

Characterization of a mutation in yeast causing nonrandom chromosome loss during mitosis. Genetics (1978) 3.21

DNA structure-dependent requirements for yeast RAD genes in gene conversion. Nature (1995) 3.15

Localization and anchoring of mRNA in budding yeast. Curr Biol (1999) 3.12

Capture of retrotransposon DNA at the sites of chromosomal double-strand breaks. Nature (1996) 3.07

Rad52-independent mitotic gene conversion in Saccharomyces cerevisiae frequently results in chromosomal loss. Genetics (1985) 3.01

Genetic manipulation of centromere function. Mol Cell Biol (1987) 2.97

The structure and evolution of subtelomeric Y' repeats in Saccharomyces cerevisiae. Genetics (1992) 2.96

DNA length dependence of the single-strand annealing pathway and the role of Saccharomyces cerevisiae RAD59 in double-strand break repair. Mol Cell Biol (2000) 2.95

Homothallic conversions of yeast mating-type genes occur by intrachromosomal recombination. Cell (1980) 2.95

Genetic and physical analysis of double-strand break repair and recombination in Saccharomyces cerevisiae. Genetics (1989) 2.93

Site-specific recombination determined by I-SceI, a mitochondrial group I intron-encoded endonuclease expressed in the yeast nucleus. Genetics (1992) 2.92

RAD1 and RAD10, but not other excision repair genes, are required for double-strand break-induced recombination in Saccharomyces cerevisiae. Mol Cell Biol (1995) 2.90

Double-strand break repair in yeast requires both leading and lagging strand DNA polymerases. Cell (1999) 2.89

Search for a resonance decaying into WZ boson pairs in pp collisions. Phys Rev Lett (2010) 2.83

Gene conversions and crossing over during homologous and homeologous ectopic recombination in Saccharomyces cerevisiae. Genetics (1993) 2.83

Expansions and contractions in a tandem repeat induced by double-strand break repair. Mol Cell Biol (1998) 2.79

The chromosome end in yeast: its mosaic nature and influence on recombinational dynamics. Genetics (1994) 2.70

Chromosome break-induced DNA replication leads to nonreciprocal translocations and telomere capture. Genetics (1998) 2.55

Pleiotropic plasma membrane ATPase mutations of Saccharomyces cerevisiae. Mol Cell Biol (1987) 2.54

Rearrangements of highly polymorphic regions near telomeres of Saccharomyces cerevisiae. Mol Cell Biol (1984) 2.52

New telomeres in yeast are initiated with a highly selected subset of TG1-3 repeats. Genes Dev (1993) 2.48

NEJ1 controls non-homologous end joining in Saccharomyces cerevisiae. Nature (2001) 2.42

Position effects in ectopic and allelic mitotic recombination in Saccharomyces cerevisiae. Genetics (1989) 2.41

Length and distribution of meiotic gene conversion tracts and crossovers in Saccharomyces cerevisiae. Genetics (1989) 2.38

Meiotic and mitotic behavior of dicentric chromosomes in Saccharomyces cerevisiae. Genetics (1984) 2.37

Genetic analysis of yeast RPA1 reveals its multiple functions in DNA metabolism. Genetics (1998) 2.37

Healing of broken linear dicentric chromosomes in yeast. Genetics (1984) 2.35

Physical monitoring of mating type switching in Saccharomyces cerevisiae. Mol Cell Biol (1988) 2.33

Genetic requirements for RAD51- and RAD54-independent break-induced replication repair of a chromosomal double-strand break. Mol Cell Biol (2001) 2.32

Break-induced replication: a review and an example in budding yeast. Proc Natl Acad Sci U S A (2001) 2.31

Evidence of Chromosomal Breaks near the Mating-Type Locus of SACCHAROMYCES CEREVISIAE That Accompany MATalpha xMATalpha Matings. Genetics (1981) 2.28

Detection of heteroduplex DNA molecules among the products of Saccharomyces cerevisiae meiosis. Proc Natl Acad Sci U S A (1990) 2.26

Control of microtubule dynamics by Stu2p is essential for spindle orientation and metaphase chromosome alignment in yeast. Mol Biol Cell (2001) 2.16

Cycloheximide-resistant temperature-sensitive lethal mutations of Saccharomyces cerevisiae. Genetics (1988) 2.15

Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant. Chromosome Res (2013) 2.12

Role of yeast SIR genes and mating type in directing DNA double-strand breaks to homologous and non-homologous repair paths. Curr Biol (1999) 2.11

The role of the proteins Kar9 and Myo2 in orienting the mitotic spindle of budding yeast. Curr Biol (2000) 2.09

Deletions and single base pair changes in the yeast mating type locus that prevent homothallic mating type conversions. Proc Natl Acad Sci U S A (1983) 2.09

Clinical and economic choices in anaesthesia for day surgery: a prospective randomised controlled trial. Anaesthesia (2003) 2.08

Heteroduplex formation and mismatch repair of the "stuck" mutation during mating-type switching in Saccharomyces cerevisiae. Mol Cell Biol (1991) 1.98

A 700 bp cis-acting region controls mating-type dependent recombination along the entire left arm of yeast chromosome III. Cell (1996) 1.94

Physical monitoring of meiotic recombination in Saccharomyces cerevisiae. Cold Spring Harb Symp Quant Biol (1984) 1.94

Mitotic recombination among subtelomeric Y' repeats in Saccharomyces cerevisiae. Genetics (1990) 1.91

Mismatch repair-induced meiotic recombination requires the pms1 gene product. Genetics (1990) 1.91

Colcemid inhibition of cell growth and the characterization of a colcemid-binding activity in Saccharomyces cerevisiae. J Cell Biol (1972) 1.89

Bisexual mating behavior in a diploid of Saccharomyces cerevisiae: evidence for genetically controlled non-random chromosome loss during vegetative growth. Genetics (1974) 1.88

The subtelomeric Y' repeat family in Saccharomyces cerevisiae: an experimental system for repeated sequence evolution. Genetics (1990) 1.79

Control of spindle polarity and orientation in Saccharomyces cerevisiae. Trends Cell Biol (2001) 1.74

Chromatin structure of altered yeast centromeres. Proc Natl Acad Sci U S A (1988) 1.74

Messenger ribonucleic acid and protein metabolism during sporulation of Saccharomyces cerevisiae. J Bacteriol (1980) 1.73

Relationship between the nerve action potential and transmitter release from sympathetic postganglionic nerve terminals. Nature (1987) 1.70

Transverse-momentum and pseudorapidity distributions of charged hadrons in pp collisions at square root of s = 7 TeV. Phys Rev Lett (2010) 1.67

Removal of one nonhomologous DNA end during gene conversion by a RAD1- and MSH2-independent pathway. Genetics (1999) 1.67

Dynamic positioning of mitotic spindles in yeast: role of microtubule motors and cortical determinants. Mol Biol Cell (2000) 1.65

Imaging green fluorescent protein fusion proteins in Saccharomyces cerevisiae. Curr Biol (1997) 1.63

Klippel-Trenaunay syndrome. Am J Med Genet (1998) 1.62

Microtubule dynamics from mating through the first zygotic division in the budding yeast Saccharomyces cerevisiae. J Cell Biol (1999) 1.62

Identification of a mid-anaphase checkpoint in budding yeast. J Cell Biol (1997) 1.61

Acquisition and processing of a conditional dicentric chromosome in Saccharomyces cerevisiae. Mol Cell Biol (1989) 1.61

Phosphorylation of gamma-tubulin regulates microtubule organization in budding yeast. Dev Cell (2001) 1.60

Cell cycle dependency of sporulation in Saccharomyces cerevisiae. J Bacteriol (1972) 1.59

The role of actin in spindle orientation changes during the Saccharomyces cerevisiae cell cycle. J Cell Biol (1999) 1.57

Study of the mass and spin-parity of the Higgs boson candidate via its decays to Z boson pairs. Phys Rev Lett (2013) 1.56

Recombination-induced CAG trinucleotide repeat expansions in yeast involve the MRE11-RAD50-XRS2 complex. EMBO J (2000) 1.56

Perinatal characteristics of newborns relinquished at birth. Am J Public Health (1983) 1.55

MATa donor preference in yeast mating-type switching: activation of a large chromosomal region for recombination. Genes Dev (1995) 1.54

Gene targeting by linear duplex DNA frequently occurs by assimilation of a single strand that is subject to preferential mismatch correction. Proc Natl Acad Sci U S A (1997) 1.53

Measurement of the forward-backward charge asymmetry in top-quark pair production. Phys Rev Lett (2008) 1.53

Nucleosome depletion alters the chromatin structure of Saccharomyces cerevisiae centromeres. Mol Cell Biol (1990) 1.46

Measurement of the W boson mass with the D0 detector. Phys Rev Lett (2012) 1.46