Characterization of RGS5 in regulation of G protein-coupled receptor signaling.

PubWeight™: 1.10‹?› | Rank: Top 10%

🔗 View Article (PMID 11253162)

Published in Life Sci on February 16, 2001

Authors

J Zhou1, K Moroi, M Nishiyama, H Usui, N Seki, J Ishida, A Fukamizu, S Kimura

Author Affiliations

1: Department of Biochemistry and Molecular Pharmacology, Chiba University Graduate School of Medicine, Japan.

Articles citing this

RGS4 and RGS5 are in vivo substrates of the N-end rule pathway. Proc Natl Acad Sci U S A (2005) 2.35

Transcription profiling of platelet-derived growth factor-B-deficient mouse embryos identifies RGS5 as a novel marker for pericytes and vascular smooth muscle cells. Am J Pathol (2003) 1.74

R4 RGS proteins: regulation of G-protein signaling and beyond. Pharmacol Ther (2007) 1.63

Regulator of G-protein signaling 5 (RGS5) protein: a novel marker of cancer vasculature elicited and sustained by the tumor's proangiogenic microenvironment. Cell Mol Life Sci (2011) 1.62

How regulators of G protein signaling achieve selective regulation. J Mol Biol (2006) 1.34

Generation and characterization of rgs5 mutant mice. Mol Cell Biol (2008) 1.13

The aorta and heart differentially express RGS (regulators of G-protein signalling) proteins that selectively regulate sphingosine 1-phosphate, angiotensin II and endothelin-1 signalling. Biochem J (2003) 1.03

Regulation of GPCR signaling in hypertension. Biochim Biophys Acta (2010) 1.02

Specificity of RGS10A as a key component in the RANKL signaling mechanism for osteoclast differentiation. J Cell Sci (2007) 1.00

Profiling of Hodgkin's lymphoma cell line L1236 and germinal center B cells: identification of Hodgkin's lymphoma-specific genes. Mol Med (2003) 0.87

Pathophysiology of tumor neovascularization. Vasc Health Risk Manag (2005) 0.86

PDGF-dependent regulation of regulator of G protein signaling-5 expression and vascular smooth muscle cell functionality. Am J Physiol Cell Physiol (2011) 0.83

Regulator of G-Protein Signaling 5 Reduces HeyA8 Ovarian Cancer Cell Proliferation and Extends Survival in a Murine Tumor Model. Biochem Res Int (2012) 0.79

Regulator of G-protein signaling-5 is a marker of hepatic stellate cells and expression mediates response to liver injury. PLoS One (2014) 0.78

Anti‑angiogenic therapy for normalization of tumor vasculature: A potential effect of Buyang Huanwu decoction on nude mice bearing human hepatocellular carcinoma xenografts with high metastatic potential. Mol Med Rep (2016) 0.75

MicroRNAs that target RGS5. Iran J Basic Med Sci (2015) 0.75

Regulator of G-protein signaling - 5 (RGS5) is a novel repressor of hedgehog signaling. PLoS One (2013) 0.75

Articles by these authors

A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature (1988) 27.60

The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat Med (2001) 16.51

A gene map of the human genome. Science (1996) 14.32

Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase. Nat Med (2002) 14.15

Genistein, a specific inhibitor of tyrosine-specific protein kinases. J Biol Chem (1987) 10.61

Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. DNA Res (1996) 10.06

The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes. Proc Natl Acad Sci U S A (1989) 7.41

Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor. Nature (1991) 7.11

FK-506, a novel immunosuppressant isolated from a Streptomyces. II. Immunosuppressive effect of FK-506 in vitro. J Antibiot (Tokyo) (1987) 7.07

Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor. Science (1995) 6.03

Expression of endothelin-1 in the lungs of patients with pulmonary hypertension. N Engl J Med (1993) 4.91

FK-506, a novel immunosuppressant isolated from a Streptomyces. I. Fermentation, isolation, and physico-chemical and biological characteristics. J Antibiot (Tokyo) (1987) 4.54

Expression of cyclooxygenase-1 and -2 in human colorectal cancer. Cancer Res (1995) 4.52

The core protein of hepatitis C virus induces hepatocellular carcinoma in transgenic mice. Nat Med (1998) 4.48

Biological profiles of highly potent novel endothelin antagonists selective for the ETA receptor. Life Sci (1992) 4.39

Loss of Nkx2.1 homeobox gene function results in a ventral to dorsal molecular respecification within the basal telencephalon: evidence for a transformation of the pallidum into the striatum. Development (1999) 4.26

A ligand-gated association between cytoplasmic domains of UNC5 and DCC family receptors converts netrin-induced growth cone attraction to repulsion. Cell (1999) 4.25

Mice lacking the vitamin D receptor exhibit impaired bone formation, uterine hypoplasia and growth retardation after weaning. Nat Genet (1997) 3.89

Evaluation of acridinium-ester-labeled DNA probes for identification of Mycobacterium tuberculosis and Mycobacterium avium-Mycobacterium intracellulare complex in culture. J Clin Microbiol (1991) 3.88

Characterization of the common genetic defect in humans deficient in debrisoquine metabolism. Nature (1988) 3.69

Hereditary progressive dystonia with marked diurnal fluctuation caused by mutations in the GTP cyclohydrolase I gene. Nat Genet (1994) 3.39

Regulation of the phosphate regulon of Escherichia coli. Activation of pstS transcription by PhoB protein in vitro. J Mol Biol (1988) 3.14

Promoter analysis of the mouse sterol regulatory element-binding protein-1c gene. J Biol Chem (2000) 3.11

Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia. Diabetes (2000) 3.01

Human thyroid peroxidase: complete cDNA and protein sequence, chromosome mapping, and identification of two alternately spliced mRNAs. Proc Natl Acad Sci U S A (1987) 3.00

Primary structure, synthesis, and biological activity of rat endothelin, an endothelium-derived vasoconstrictor peptide. Proc Natl Acad Sci U S A (1988) 2.99

Clonal isolation of muscle-derived cells capable of enhancing muscle regeneration and bone healing. J Cell Biol (2000) 2.75

The mechanisms by which both heterozygous peroxisome proliferator-activated receptor gamma (PPARgamma) deficiency and PPARgamma agonist improve insulin resistance. J Biol Chem (2001) 2.69

Defects in tracheoesophageal and lung morphogenesis in Nkx2.1(-/-) mouse embryos. Dev Biol (1999) 2.69

Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoter. Mol Cell Biol (2001) 2.68

Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1. DNA Res (1995) 2.61

miR-145 and miR-133a function as tumour suppressors and directly regulate FSCN1 expression in bladder cancer. Br J Cancer (2010) 2.51

Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1. DNA Res (1994) 2.38

Localization of allodeterminants on H-2Kb antigens determined with monoclonal antibodies and H-2 mutant mice. Proc Natl Acad Sci U S A (1982) 2.33

T cell activation-associated hepatic injury: mediation by tumor necrosis factors and protection by interleukin 6. J Exp Med (1994) 2.31

Discovery of FK-506, a novel immunosuppressant isolated from Streptomyces tsukubaensis. Transplant Proc (1987) 2.30

The signal-dependent coactivator CBP is a nuclear target for pp90RSK. Cell (1996) 2.26

The tumour-suppressive function of miR-1 and miR-133a targeting TAGLN2 in bladder cancer. Br J Cancer (2011) 2.25

Membrane hyperpolarization inhibits agonist-induced synthesis of inositol 1,4,5-trisphosphate in rabbit mesenteric artery. J Physiol (1992) 2.20

Positive inotropic action of novel vasoconstrictor peptide endothelin on guinea pig atria. Am J Physiol (1988) 2.18

Frequent presence of HBV in the sera of HBsAg-negative, anti-HBc-positive blood donors. Transfusion (2001) 2.16

Nodeless superconducting gap in A(x)Fe2Se2 (A=K,Cs) revealed by angle-resolved photoemission spectroscopy. Nat Mater (2011) 2.16

Connectin, an elastic protein of muscle. Characterization and Function. J Biochem (1977) 2.14

Angiotensinogen-deficient mice with hypotension. J Biol Chem (1994) 2.11

Adipose angiotensinogen is involved in adipose tissue growth and blood pressure regulation. FASEB J (2001) 2.09

Nucleotide sequence of the streptothricin acetyltransferase gene from Streptomyces lavendulae and its expression in heterologous hosts. J Bacteriol (1987) 2.08

Hypertension induced in pregnant mice by placental renin and maternal angiotensinogen. Science (1996) 2.04

An outbreak of enteritis due to Yersinia enterocolitica occurring at a junior high school. Jpn J Microbiol (1973) 2.02

Measurement of soil contamination by radionuclides due to the Fukushima Dai-ichi Nuclear Power Plant accident and associated estimated cumulative external dose estimation. J Environ Radioact (2011) 1.98

Inhibition of RXR and PPARgamma ameliorates diet-induced obesity and type 2 diabetes. J Clin Invest (2001) 1.97

DNA binding of PhoB and its interaction with RNA polymerase. J Mol Biol (1996) 1.97

Laparoscopic removal of a large gastric trichobezoar. J Pediatr Surg (1998) 1.96

Calcium signalling in the guidance of nerve growth by netrin-1. Nature (2000) 1.96

Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription. Genes Cells (2001) 1.95

Disruption of the DT diaphorase (NQO1) gene in mice leads to increased menadione toxicity. J Biol Chem (1998) 1.94

Polymorphism of the 5'-flanking region of the human tumor necrosis factor (TNF)-alpha gene in Japanese. Tissue Antigens (1998) 1.93

Structure and regulation of the Escherichia coli ruv operon involved in DNA repair and recombination. J Bacteriol (1988) 1.92

Construction and characterization of human brain cDNA libraries suitable for analysis of cDNA clones encoding relatively large proteins. DNA Res (1997) 1.92

Oxidative stress in the absence of inflammation in a mouse model for hepatitis C virus-associated hepatocarcinogenesis. Cancer Res (2001) 1.91

The Pro12Ala polymorphism in PPAR gamma2 may confer resistance to type 2 diabetes. Biochem Biophys Res Commun (2000) 1.91

Amino acid sequence of an amyloid fibril protein of unknown origin. J Biol Chem (1972) 1.90

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. DNA Res (1997) 1.87

Molecular and cellular mechanism of endothelin regulation. Implications for vascular function. Circulation (1991) 1.86

A genetic variation in the PGC-1 gene could confer insulin resistance and susceptibility to Type II diabetes. Diabetologia (2002) 1.83

Connectin filaments link thick filaments and Z lines in frog skeletal muscle as revealed by immunoelectron microscopy. J Cell Biol (1985) 1.83

Evaluation of the therapeutic effect of radiotherapy on cervical cancer using magnetic resonance imaging. Int J Radiat Oncol Biol Phys (1999) 1.82

An about 50,000-dalton protein in adrenal medulla: a common precursor of [Met]- and [Leu]enkephalin. Science (1980) 1.81

Real-time automated PCR for early diagnosis and monitoring of cytomegalovirus infection after bone marrow transplantation. J Clin Microbiol (2000) 1.80

Comparison of the flanking regions and introns of the mouse 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible cytochrome P1-450 and P3-450 genes. J Biol Chem (1985) 1.79

A novel complex locus UGT1 encodes human bilirubin, phenol, and other UDP-glucuronosyltransferase isozymes with identical carboxyl termini. J Biol Chem (1992) 1.79

Silk fibroin of Bombyx mori is secreted, assembling a high molecular mass elementary unit consisting of H-chain, L-chain, and P25, with a 6:6:1 molar ratio. J Biol Chem (2000) 1.78

Sodic soils reclaimed with by-product from flue gas desulfurization: corn production and soil quality. Environ Pollut (2001) 1.76

N-Terminally extended human ubiquitin-conjugating enzymes (E2s) mediate the ubiquitination of RING-finger proteins, ARA54 and RNF8. Eur J Biochem (2001) 1.76

The murine Ah locus. Comparison of the complete cytochrome P1-450 and P3-450 cDNA nucleotide and amino acid sequences. J Biol Chem (1984) 1.75

Laparoscopic omental patch repair for perforated peptic ulcer. Ann Surg (1995) 1.74

Tumour suppressors miR-1 and miR-133a target the oncogenic function of purine nucleoside phosphorylase (PNP) in prostate cancer. Br J Cancer (2011) 1.74

Characterization of the transforming activity of p80, a hyperphosphorylated protein in a Ki-1 lymphoma cell line with chromosomal translocation t(2;5). Proc Natl Acad Sci U S A (1996) 1.72

Complete nucleotide sequence of the prophage VT2-Sakai carrying the verotoxin 2 genes of the enterohemorrhagic Escherichia coli O157:H7 derived from the Sakai outbreak. Genes Genet Syst (1999) 1.70

Chronic subdural hematoma, as an initial manifestation of glutaric aciduria type-1. Brain Dev (1993) 1.70

Use of real-time PCR on blood samples for diagnosis of invasive aspergillosis. Clin Infect Dis (2001) 1.69

Formation of Rathke's pouch requires dual induction from the diencephalon. Development (1998) 1.68

Effects of endothelin on the renal artery from spontaneously hypertensive and Wistar Kyoto rats. Eur J Pharmacol (1988) 1.68

Structure and regulation of rat long-chain acyl-CoA synthetase. J Biol Chem (1990) 1.68

Muscle-specific calpain, p94, responsible for limb girdle muscular dystrophy type 2A, associates with connectin through IS2, a p94-specific sequence. J Biol Chem (1995) 1.68

Portal tumor thrombus due to gastrointestinal cancer. Abdom Imaging (1999) 1.67

Inhibition of distal lung morphogenesis in Nkx2.1(-/-) embryos. Dev Dyn (2000) 1.67

Probable assignment of soluble isocitrate dehydrogenase (IDH1) to 2q33.3. Hum Genet (1985) 1.66

A prokaryotic gene cluster involved in synthesis of lysine through the amino adipate pathway: a key to the evolution of amino acid biosynthesis. Genome Res (1999) 1.65

Sonographic findings of anomalous position of the gallbladder. Abdom Imaging (1998) 1.64

Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1. DNA Res (1996) 1.64

GSK-3beta-dependent phosphorylation of adenomatous polyposis coli gene product can be modulated by beta-catenin and protein phosphatase 2A complexed with Axin. Oncogene (2000) 1.62

Essential role of insulin receptor substrate 1 (IRS-1) and IRS-2 in adipocyte differentiation. Mol Cell Biol (2001) 1.62

Hedgehog-dependent oligodendrocyte lineage specification in the telencephalon. Development (2001) 1.62

miR-489 is a tumour-suppressive miRNA target PTPN11 in hypopharyngeal squamous cell carcinoma (HSCC). Br J Cancer (2010) 1.61

Development of a host-vector system in a Rhodococcus strain and its use for expression of the cloned nitrile hydratase gene cluster. J Gen Microbiol (1992) 1.60

Detection of Pneumocystis carinii sequences by polymerase chain reaction: animal models and clinical application to noninvasive specimens. J Clin Microbiol (1991) 1.60

Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1. DNA Res (1994) 1.60

Horseshoe crab acetyl group-recognizing lectins involved in innate immunity are structurally related to fibrinogen. Proc Natl Acad Sci U S A (1999) 1.60