Published in Mol Cell Biol on January 22, 2008
Regulator of G-protein signaling 5 (RGS5) protein: a novel marker of cancer vasculature elicited and sustained by the tumor's proangiogenic microenvironment. Cell Mol Life Sci (2011) 1.62
Regulator of G protein signaling 5 protects against cardiac hypertrophy and fibrosis during biomechanical stress of pressure overload. Proc Natl Acad Sci U S A (2010) 1.38
Early loss of pericytes and perivascular stromal cell-induced scar formation after stroke. J Cereb Blood Flow Metab (2012) 1.04
Regulation of GPCR signaling in hypertension. Biochim Biophys Acta (2010) 1.02
Transgenic mice expressing an intracellular fluorescent fusion of angiotensin II demonstrate renal thrombotic microangiopathy and elevated blood pressure. Am J Physiol Heart Circ Physiol (2010) 1.01
Coronary adventitial cells are linked to perivascular cardiac fibrosis via TGFβ1 signaling in the mdx mouse model of Duchenne muscular dystrophy. J Mol Cell Cardiol (2013) 0.94
Brain pericytes: emerging concepts and functional roles in brain homeostasis. Cell Mol Neurobiol (2011) 0.91
Regulators of G-protein signaling in the heart and their potential as therapeutic targets. Circ Res (2011) 0.90
Brain pericytes acquire a microglial phenotype after stroke. Acta Neuropathol (2014) 0.87
ABCG2pos lung mesenchymal stem cells are a novel pericyte subpopulation that contributes to fibrotic remodeling. Am J Physiol Cell Physiol (2014) 0.87
Relationship between RGS5 expression and differentiation and angiogenesis of gastric carcinoma. World J Gastroenterol (2010) 0.86
Association of ATP1B1, RGS5 and SELE polymorphisms with hypertension and blood pressure in African-Americans. J Hypertens (2011) 0.84
PDGF-dependent regulation of regulator of G protein signaling-5 expression and vascular smooth muscle cell functionality. Am J Physiol Cell Physiol (2011) 0.83
Diverse functions of pericytes in cerebral blood flow regulation and ischemia. J Cereb Blood Flow Metab (2015) 0.82
RGS5 promotes arterial growth during arteriogenesis. EMBO Mol Med (2014) 0.82
A murine toolbox for imaging the neurovascular unit. Microcirculation (2015) 0.81
Endogenous brain pericytes are widely activated and contribute to mouse glioma microvasculature. PLoS One (2015) 0.79
A unifying hypothesis for scleroderma: identifying a target cell for scleroderma. Curr Rheumatol Rep (2011) 0.79
Regulator of G-protein signaling-5 is a marker of hepatic stellate cells and expression mediates response to liver injury. PLoS One (2014) 0.78
Profiling, Bioinformatic, and Functional Data on the Developing Olfactory/GnRH System Reveal Cellular and Molecular Pathways Essential for This Process and Potentially Relevant for the Kallmann Syndrome. Front Endocrinol (Lausanne) (2013) 0.78
The pericyte antigen RGS5 in perivascular soft tissue tumors. Hum Pathol (2015) 0.78
Complex network-driven view of genomic mechanisms underlying Parkinson's disease: analyses in dorsal motor vagal nucleus, locus coeruleus, and substantia nigra. Biomed Res Int (2014) 0.76
Checkpoints to the Brain: Directing Myeloid Cell Migration to the Central Nervous System. Int J Mol Sci (2016) 0.75
Regulator of G-protein signaling - 5 (RGS5) is a novel repressor of hedgehog signaling. PLoS One (2013) 0.75
Regulator of G Protein Signaling 2: A Versatile Regulator of Vascular Function. Prog Mol Biol Transl Sci (2015) 0.75
Glioblastoma progression is assisted by induction of immunosuppressive function of pericytes through interaction with tumor cells. Oncotarget (2017) 0.75
VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia. J Cell Biol (2003) 12.96
Pericyte loss and microaneurysm formation in PDGF-B-deficient mice. Science (1997) 10.54
Oxygen-induced retinopathy in the mouse. Invest Ophthalmol Vis Sci (1994) 10.46
High-throughput engineering of the mouse genome coupled with high-resolution expression analysis. Nat Biotechnol (2003) 7.47
PDGF-A signaling is a critical event in lung alveolar myofibroblast development and alveogenesis. Cell (1996) 3.60
Endothelial PDGF-B retention is required for proper investment of pericytes in the microvessel wall. Genes Dev (2003) 3.48
Slowed recovery of rod photoresponse in mice lacking the GTPase accelerating protein RGS9-1. Nature (2000) 3.11
The regulator of G protein signaling family. Annu Rev Pharmacol Toxicol (2000) 2.73
Endothelium-specific platelet-derived growth factor-B ablation mimics diabetic retinopathy. EMBO J (2002) 2.73
The N-end rule pathway as a nitric oxide sensor controlling the levels of multiple regulators. Nature (2005) 2.55
RGS4 and RGS5 are in vivo substrates of the N-end rule pathway. Proc Natl Acad Sci U S A (2005) 2.35
Multiple genes for essential-hypertension susceptibility on chromosome 1q. Am J Hum Genet (2006) 2.34
Role of the sphingosine-1-phosphate receptor EDG-1 in PDGF-induced cell motility. Science (2001) 2.17
Regulator of G-protein signaling-5 induction in pericytes coincides with active vessel remodeling during neovascularization. Blood (2004) 1.77
Pericyte-specific expression of Rgs5: implications for PDGF and EDG receptor signaling during vascular maturation. FASEB J (2003) 1.76
Emerging roles for RGS proteins in cell signalling. Trends Pharmacol Sci (1999) 1.74
Transcription profiling of platelet-derived growth factor-B-deficient mouse embryos identifies RGS5 as a novel marker for pericytes and vascular smooth muscle cells. Am J Pathol (2003) 1.74
Regulation of T cell activation, anxiety, and male aggression by RGS2. Proc Natl Acad Sci U S A (2000) 1.73
Defective N-sulfation of heparan sulfate proteoglycans limits PDGF-BB binding and pericyte recruitment in vascular development. Genes Dev (2007) 1.68
A novel transgenic marker for migrating limb muscle precursors and for vascular smooth muscle cells. Dev Dyn (2001) 1.66
RGS2 regulates signal transduction in olfactory neurons by attenuating activation of adenylyl cyclase III. Nature (2001) 1.62
EDG-1 links the PDGF receptor to Src and focal adhesion kinase activation leading to lamellipodia formation and cell migration. FASEB J (2001) 1.55
Microarray analysis of blood microvessels from PDGF-B and PDGF-Rbeta mutant mice identifies novel markers for brain pericytes. FASEB J (2006) 1.52
Divergence of RGS proteins: evidence for the existence of six mammalian RGS subfamilies. Trends Biochem Sci (1999) 1.41
N-terminal residues control proteasomal degradation of RGS2, RGS4, and RGS5 in human embryonic kidney 293 cells. Mol Pharmacol (2007) 1.35
Regulator of G protein signaling 1 (RGS1) markedly impairs Gi alpha signaling responses of B lymphocytes. J Immunol (2000) 1.11
Characterization of RGS5 in regulation of G protein-coupled receptor signaling. Life Sci (2001) 1.10
RGS16 is a negative regulator of SDF-1-CXCR4 signaling in megakaryocytes. Blood (2005) 1.10
Role of regulator of G protein signaling 16 in inflammation-induced T lymphocyte migration and activation. J Immunol (2003) 1.08
The membrane association domain of RGS16 contains unique amphipathic features that are conserved in RGS4 and RGS5. J Biol Chem (1999) 0.96
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet (2011) 13.25
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia. J Cell Biol (2003) 12.96
Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet (2009) 12.44
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants. Nat Genet (2009) 12.19
Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study. Lancet (2012) 12.10
Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis. Nature (2007) 9.09
Role of platelet-derived growth factors in physiology and medicine. Genes Dev (2008) 8.89
Endothelial/pericyte interactions. Circ Res (2005) 8.24
Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins. Nat Immunol (2003) 7.42
Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia. Nat Genet (2010) 7.08
Pericytes regulate the blood-brain barrier. Nature (2010) 6.62
A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium. Nat Genet (2009) 6.31
Pericytes: developmental, physiological, and pathological perspectives, problems, and promises. Dev Cell (2011) 6.12
Spatially restricted patterning cues provided by heparin-binding VEGF-A control blood vessel branching morphogenesis. Genes Dev (2002) 5.15
Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation. Nature (2008) 5.15
New susceptibility locus for coronary artery disease on chromosome 3q22.3. Nat Genet (2009) 5.12
Inactivating mutations in NPC1L1 and protection from coronary heart disease. N Engl J Med (2014) 4.94
A new method for large scale isolation of kidney glomeruli from mice. Am J Pathol (2002) 4.63
Impact of socioeconomic status on cancer incidence and stage at diagnosis: selected findings from the surveillance, epidemiology, and end results: National Longitudinal Mortality Study. Cancer Causes Control (2008) 4.56
Alcohol drinking in never users of tobacco, cigarette smoking in never drinkers, and the risk of head and neck cancer: pooled analysis in the International Head and Neck Cancer Epidemiology Consortium. J Natl Cancer Inst (2007) 4.55
Endothelial-pericyte interactions in angiogenesis. Cell Tissue Res (2003) 4.39
Human papillomavirus, smoking, and sexual practices in the etiology of anal cancer. Cancer (2004) 4.04
Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits. PLoS Genet (2011) 3.92
Apolipoprotein E controls cerebrovascular integrity via cyclophilin A. Nature (2012) 3.80
Endothelial-mural cell signaling in vascular development and angiogenesis. Arterioscler Thromb Vasc Biol (2009) 3.78
Activation of PDGF-CC by tissue plasminogen activator impairs blood-brain barrier integrity during ischemic stroke. Nat Med (2008) 3.64
Endothelial PDGF-B retention is required for proper investment of pericytes in the microvessel wall. Genes Dev (2003) 3.48
Anal cancer incidence and survival: the surveillance, epidemiology, and end results experience, 1973-2000. Cancer (2004) 3.40
Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs. Nat Med (2013) 3.35
Interaction between tobacco and alcohol use and the risk of head and neck cancer: pooled analysis in the International Head and Neck Cancer Epidemiology Consortium. Cancer Epidemiol Biomarkers Prev (2009) 3.33
Endothelial and nonendothelial sources of PDGF-B regulate pericyte recruitment and influence vascular pattern formation in tumors. J Clin Invest (2003) 3.31
A hierarchical network controls protein translation during murine embryonic stem cell self-renewal and differentiation. Cell Stem Cell (2008) 3.18
Common variation in KITLG and at 5q31.3 predisposes to testicular germ cell cancer. Nat Genet (2009) 2.85
Penile cancer: importance of circumcision, human papillomavirus and smoking in in situ and invasive disease. Int J Cancer (2005) 2.79
Endothelium-specific platelet-derived growth factor-B ablation mimics diabetic retinopathy. EMBO J (2002) 2.73
Polymorphisms within the C-reactive protein (CRP) promoter region are associated with plasma CRP levels. Am J Hum Genet (2005) 2.71
Mutations in the gene encoding PDGF-B cause brain calcifications in humans and mice. Nat Genet (2013) 2.62
Pericytes limit tumor cell metastasis. J Clin Invest (2006) 2.55
Endothelium-specific ablation of PDGFB leads to pericyte loss and glomerular, cardiac and placental abnormalities. Development (2004) 2.44
Pericytes and vascular stability. Exp Cell Res (2005) 2.39
Quality of race, Hispanic ethnicity, and immigrant status in population-based cancer registry data: implications for health disparity studies. Cancer Causes Control (2007) 2.36
Pericytes and the pathogenesis of diabetic retinopathy. Diabetes (2002) 2.31
Cytokine detection by antibody-based proximity ligation. Proc Natl Acad Sci U S A (2004) 2.29
The Y deletion gr/gr and susceptibility to testicular germ cell tumor. Am J Hum Genet (2005) 2.26
Cortical and retinal defects caused by dosage-dependent reductions in VEGF-A paracrine signaling. Dev Biol (2003) 2.24
Calcification of advanced atherosclerotic lesions in the innominate arteries of ApoE-deficient mice: potential role of chondrocyte-like cells. Arterioscler Thromb Vasc Biol (2005) 2.18
Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies. J Am Coll Cardiol (2010) 2.17
Recruitment and follow-up of adolescent and young adult cancer survivors: the AYA HOPE Study. J Cancer Surviv (2011) 2.15
Changes in diet, physical activity, and supplement use among adults diagnosed with cancer. J Am Diet Assoc (2003) 2.11
Neuropilin-1 is required for endothelial tip cell guidance in the developing central nervous system. Dev Dyn (2004) 2.11
Type II diabetes and metabolic syndrome in relation to head and neck squamous cell carcinoma risk: a SEER-Medicare database study. Cancer Epidemiol (2013) 1.99
Total exposure and exposure rate effects for alcohol and smoking and risk of head and neck cancer: a pooled analysis of case-control studies. Am J Epidemiol (2009) 1.97
Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction. Circulation (2011) 1.96
Enhanced extracellular matrix accumulation in restenosis of coronary arteries after stent deployment. J Am Coll Cardiol (2002) 1.92
Increased ethanol resistance and consumption in Eps8 knockout mice correlates with altered actin dynamics. Cell (2006) 1.92
A population-based study of squamous cell vaginal cancer: HPV and cofactors. Gynecol Oncol (2002) 1.90
Analysis of mural cell recruitment to tumor vessels. Circulation (2002) 1.90
A specific requirement for PDGF-C in palate formation and PDGFR-alpha signaling. Nat Genet (2004) 1.87
Osteoprotegerin inactivation accelerates advanced atherosclerotic lesion progression and calcification in older ApoE-/- mice. Arterioscler Thromb Vasc Biol (2006) 1.86
Types of alternative medicine used by patients with breast, colon, or prostate cancer: predictors, motives, and costs. J Altern Complement Med (2002) 1.85
A randomized controlled trial of interventions to promote cervical cancer screening among Chinese women in North America. J Natl Cancer Inst (2002) 1.83
Pericyte-specific expression of Rgs5: implications for PDGF and EDG receptor signaling during vascular maturation. FASEB J (2003) 1.76
Meta-analysis identifies four new loci associated with testicular germ cell tumor. Nat Genet (2013) 1.74
Arterial remodeling in [corrected] subclinical carotid artery disease. JACC Cardiovasc Imaging (2009) 1.74
Transcription profiling of platelet-derived growth factor-B-deficient mouse embryos identifies RGS5 as a novel marker for pericytes and vascular smooth muscle cells. Am J Pathol (2003) 1.74
Cigarette, cigar, and pipe smoking and the risk of head and neck cancers: pooled analysis in the International Head and Neck Cancer Epidemiology Consortium. Am J Epidemiol (2013) 1.73
Platelet-derived growth factor production by B16 melanoma cells leads to increased pericyte abundance in tumors and an associated increase in tumor growth rate. Cancer Res (2004) 1.72
Sexual behaviours and the risk of head and neck cancers: a pooled analysis in the International Head and Neck Cancer Epidemiology (INHANCE) consortium. Int J Epidemiol (2009) 1.70
Large-scale identification of genes implicated in kidney glomerulus development and function. EMBO J (2006) 1.69
A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium. PLoS Genet (2011) 1.68
Defective N-sulfation of heparan sulfate proteoglycans limits PDGF-BB binding and pericyte recruitment in vascular development. Genes Dev (2007) 1.68
The sphingosine-1-phosphate receptor S1PR1 restricts sprouting angiogenesis by regulating the interplay between VE-cadherin and VEGFR2. Dev Cell (2012) 1.66
Paracrine signaling by platelet-derived growth factor-CC promotes tumor growth by recruitment of cancer-associated fibroblasts. Cancer Res (2009) 1.65
A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease. Circ Cardiovasc Genet (2011) 1.63
Gene expression profiling identifies genes predictive of oral squamous cell carcinoma. Cancer Epidemiol Biomarkers Prev (2008) 1.60
Expression profiling identifies 147 genes contributing to a unique primate neointimal smooth muscle cell phenotype. Arterioscler Thromb Vasc Biol (2002) 1.60
The adventitia: a dynamic interface containing resident progenitor cells. Arterioscler Thromb Vasc Biol (2011) 1.58
Survival following parathyroidectomy among United States dialysis patients. Kidney Int (2004) 1.57
Pooled analysis of alcohol dehydrogenase genotypes and head and neck cancer: a HuGE review. Am J Epidemiol (2004) 1.56
Identification of a core set of 58 gene transcripts with broad and specific expression in the microvasculature. Arterioscler Thromb Vasc Biol (2008) 1.53
Microarray analysis of blood microvessels from PDGF-B and PDGF-Rbeta mutant mice identifies novel markers for brain pericytes. FASEB J (2006) 1.52
Feasibility of including cellular telephone numbers in random digit dialing for epidemiologic case-control studies. Am J Epidemiol (2010) 1.52
Rates and determinants of oral human papillomavirus infection in young men. Sex Transm Dis (2012) 1.48
A short acculturation scale for Mexican-American populations. Ethn Dis (2005) 1.45
Capillary regeneration in scleroderma: stem cell therapy reverses phenotype? PLoS One (2008) 1.42
Comprehensive analysis of HLA-A, HLA-B, HLA-C, HLA-DRB1, and HLA-DQB1 loci and squamous cell cervical cancer risk. Cancer Res (2008) 1.40
Association of history of allergies and influenza-like infections with laryngeal cancer in a case-control study. Eur Arch Otorhinolaryngol (2015) 1.39
Mouthwash use and cancer of the head and neck: a pooled analysis from the International Head and Neck Cancer Epidemiology Consortium. Eur J Cancer Prev (2016) 1.38
Combined analysis of monocyte and lymphocyte messenger RNA expression with serum protein profiles in patients with scleroderma. Arthritis Rheum (2008) 1.38
Vascular remodeling: hemodynamic and biochemical mechanisms underlying Glagov's phenomenon. Arterioscler Thromb Vasc Biol (2007) 1.36
Impact of cancer on work and education among adolescent and young adult cancer survivors. J Clin Oncol (2012) 1.35
Polycystic ovary syndrome and risk for long-term diabetes and dyslipidemia. Obstet Gynecol (2011) 1.35
A second independent locus within DMRT1 is associated with testicular germ cell tumor susceptibility. Hum Mol Genet (2011) 1.34