Published in Regul Pept on June 15, 2001
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Apelin, a potent diuretic neuropeptide counteracting vasopressin actions through inhibition of vasopressin neuron activity and vasopressin release. Proc Natl Acad Sci U S A (2004) 1.58
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Apelin is decreased with human preterm and term labor and regulates prolabor mediators in human primary amnion cells. Reprod Sci (2013) 0.82
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Discovery of 4-oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-nitrobenzoate (ML221) as a functional antagonist of the apelin (APJ) receptor. Bioorg Med Chem Lett (2012) 0.81
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Apelin serum level in Egyptian patients with chronic hepatitis C. Mediators Inflamm (2011) 0.81
Upregulation of the apelin-APJ pathway promotes neointima formation in the carotid ligation model in mouse. Cardiovasc Res (2010) 0.80
Reduction of arterial stiffness by exercise training is associated with increasing plasma apelin level in middle-aged and older adults. PLoS One (2014) 0.80
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Effects of acute intravenous infusion of apelin on left ventricular function in dogs with advanced heart failure. J Card Fail (2013) 0.79
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Apelin in epiretinal membranes of patients with proliferative diabetic retinopathy. Mol Vis (2014) 0.78
Apelin acts in the subfornical organ to influence neuronal excitability and cardiovascular function. J Physiol (2013) 0.78
Characterization of the apelin -1860T>C polymorphism in Turkish coronary artery disease patients and healthy individuals. Int J Physiol Pathophysiol Pharmacol (2015) 0.77
Cardiac action of the first G protein biased small molecule apelin agonist. Biochem Pharmacol (2016) 0.77
Effects of apelin on the cardiovascular system. Heart Fail Rev (2015) 0.77
Altered glucose homeostasis is associated with increased serum apelin levels in type 2 diabetes mellitus. PLoS One (2012) 0.77
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Apelin-13 inhibits large-conductance Ca2+-activated K+ channels in cerebral artery smooth muscle cells via a PI3-kinase dependent mechanism. PLoS One (2013) 0.76
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Apelin receptor (APJ) expression during cardiopulmonary bypass in children undergoing surgical repair. PLoS One (2014) 0.75
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The analgesic effect of apelin-13 and its mechanism of action within the nitric oxide and serotonin pathways. Hippokratia (2016) 0.75
Clinical Implications of the Serum Apelin Level on Portal Hypertension and Prognosis of Liver Cirrhosis. Gut Liver (2016) 0.75
The differential effects of low and high doses of apelin through opioid receptors on the blood pressure of rats with renovascular hypertension. Hypertens Res (2017) 0.75
RNA-seq-based transcriptome profiling reveals differential gene expression in the lungs of Sprague-Dawley rats during early-phase acute hypobaric hypoxia. Mol Genet Genomics (2015) 0.75
Prospective evaluation of the diagnostic value of plasma apelin 12 levels for differentiating patients with moyamoya and intracranial atherosclerotic diseases. Sci Rep (2017) 0.75
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