Published in Toxicol Sci on July 01, 2001
Interstrain differences in the liver effects of trichloroethylene in a multistrain panel of inbred mice. Toxicol Sci (2010) 0.99
Epigenetic effects of the continuous exposure to peroxisome proliferator WY-14,643 in mouse liver are dependent upon peroxisome proliferator activated receptor alpha. Mutat Res (2007) 0.98
Nickel compounds induce apoptosis in human bronchial epithelial Beas-2B cells by activation of c-Myc through ERK pathway. Toxicol Appl Pharmacol (2008) 0.89
Mechanisms of peroxisome proliferator-induced DNA hypomethylation in rat liver. Mutat Res (2008) 0.86
Epigenetic aspects of genotoxic and non-genotoxic hepatocarcinogenesis: studies in rodents. Environ Mol Mutagen (2008) 0.84
The genome sequence of Drosophila melanogaster. Science (2000) 74.32
Calculating structures and free energies of complex molecules: combining molecular mechanics and continuum models. Acc Chem Res (2000) 10.78
A new class of membrane-bound chemokine with a CX3C motif. Nature (1997) 7.87
NURD, a novel complex with both ATP-dependent chromatin-remodeling and histone deacetylase activities. Mol Cell (1998) 7.58
Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein. Science (1999) 7.51
Binding and stimulation of HIV-1 integrase by a human homolog of yeast transcription factor SNF5. Science (1994) 5.47
Co-adjuvant effects of retinoic acid and IL-15 induce inflammatory immunity to dietary antigens. Nature (2011) 5.41
Crystal structure of an IHF-DNA complex: a protein-induced DNA U-turn. Cell (1996) 5.38
Genetic diversity and disease control in rice. Nature (2000) 5.34
Rapid evolution of male reproductive genes in the descent of man. Nature (2000) 5.33
Identifying tumor suppressors in genetic mosaics: the Drosophila lats gene encodes a putative protein kinase. Development (1995) 5.18
Rapid and phosphoinositol-dependent binding of the SWI/SNF-like BAF complex to chromatin after T lymphocyte receptor signaling. Cell (1998) 4.95
Changes in physical activity patterns in the United States, by sex and cross-sectional age. Med Sci Sports Exerc (2000) 4.63
Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain. J Neurochem (2001) 4.45
Bone development. Annu Rev Cell Dev Biol (2000) 4.24
Synthetic-lethal interactions identify two novel genes, SLA1 and SLA2, that control membrane cytoskeleton assembly in Saccharomyces cerevisiae. J Cell Biol (1993) 4.03
Dietary fiber, weight gain, and cardiovascular disease risk factors in young adults. JAMA (1999) 3.34
Regulation of dendritic spine morphology by SPAR, a PSD-95-associated RapGAP. Neuron (2001) 3.30
The human SWI/SNF-B chromatin-remodeling complex is related to yeast rsc and localizes at kinetochores of mitotic chromosomes. Proc Natl Acad Sci U S A (2000) 3.16
Impact of a computer-based patient record system on data collection, knowledge organization, and reasoning. J Am Med Inform Assoc (2000) 3.16
Direct analysis and identification of proteins in mixtures by LC/MS/MS and database searching at the low-femtomole level. Anal Chem (1997) 3.09
A binding protein-dependent transport system in Streptococcus mutans responsible for multiple sugar metabolism. J Biol Chem (1992) 3.03
Protective mucosal immunity elicited by targeted iliac lymph node immunization with a subunit SIV envelope and core vaccine in macaques. Nat Med (1996) 2.96
High prevalence of abnormal acid gastro-oesophageal reflux in idiopathic pulmonary fibrosis. Eur Respir J (2006) 2.94
BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer. Cell (2000) 2.94
Isozyme frequency patterns in Drosophila pavani associated with geographical and seasonal variables. Genetics (1972) 2.90
Zonulin, a newly discovered modulator of intestinal permeability, and its expression in coeliac disease. Lancet (2000) 2.82
NMDA receptors mediate calcium accumulation in myelin during chemical ischaemia. Nature (2005) 2.74
Processing of the notch ligand delta by the metalloprotease Kuzbanian. Science (1999) 2.71
Paternal population history of East Asia: sources, patterns, and microevolutionary processes. Am J Hum Genet (2001) 2.71
A specificity and targeting subunit of a human SWI/SNF family-related chromatin-remodeling complex. Mol Cell Biol (2000) 2.70
Ribosomal protein S7 as a novel modulator of p53-MDM2 interaction: binding to MDM2, stabilization of p53 protein, and activation of p53 function. Oncogene (2007) 2.68
The intermediate endpoint effect in logistic and probit regression. Clin Trials (2007) 2.67
Type 1 protein phosphatase acts in opposition to IpL1 protein kinase in regulating yeast chromosome segregation. Mol Cell Biol (1994) 2.59
Safety of hydroxyurea in children with sickle cell anemia: results of the HUG-KIDS study, a phase I/II trial. Pediatric Hydroxyurea Group. Blood (1999) 2.59
Atrial G protein-activated K+ channel: expression cloning and molecular properties. Proc Natl Acad Sci U S A (1993) 2.57
Sino-MONICA project: a collaborative study on trends and determinants in cardiovascular diseases in China, Part i: morbidity and mortality monitoring. Circulation (2001) 2.56
Use of MM-PBSA in reproducing the binding free energies to HIV-1 RT of TIBO derivatives and predicting the binding mode to HIV-1 RT of efavirenz by docking and MM-PBSA. J Am Chem Soc (2001) 2.55
Hormonal changes in the grains of rice subjected to water stress during grain filling. Plant Physiol (2001) 2.52
The Ski oncoprotein interacts with the Smad proteins to repress TGFbeta signaling. Genes Dev (1999) 2.52
Dietary agents in cancer prevention: flavonoids and isoflavonoids. Pharmacol Ther (2001) 2.51
Genetic influence on the structural variations of the abnormal prion protein. Proc Natl Acad Sci U S A (2000) 2.46
All-cause mortality and cardiovascular disease mortality in three American Indian populations, aged 45-74 years, 1984-1988. The Strong Heart Study. Am J Epidemiol (1998) 2.43
Biomarker risk assessment and bladder cancer detection in a cohort exposed to benzidine. J Natl Cancer Inst (2001) 2.41
Transfusion and alloimmunization in sickle cell disease. The Cooperative Study of Sickle Cell Disease. Blood (1990) 2.38
Pattern of marine mass extinction near the Permian-Triassic boundary in South China. Science (2000) 2.38
De novo amyloid proteins from designed combinatorial libraries. Proc Natl Acad Sci U S A (1999) 2.38
Predicting caries in permanent teeth from caries in primary teeth: an eight-year cohort study. J Dent Res (2002) 2.35
ATPase activity of the cystic fibrosis transmembrane conductance regulator. J Biol Chem (1996) 2.33
Hindered diffusion of high molecular weight compounds in brain extracellular microenvironment measured with integrative optical imaging. Biophys J (1993) 2.32
A randomized controlled phase III trial of recombinant human granulocyte colony-stimulating factor (filgrastim) for treatment of severe chronic neutropenia. Blood (1993) 2.29
Regulation of Ca2+ signaling in transgenic mouse cardiac myocytes overexpressing calsequestrin. J Clin Invest (1998) 2.29
A family of chromatin remodeling factors related to Williams syndrome transcription factor. Proc Natl Acad Sci U S A (2000) 2.24
CCR6, a CC chemokine receptor that interacts with macrophage inflammatory protein 3alpha and is highly expressed in human dendritic cells. J Exp Med (1997) 2.24
The immunodominant major histocompatibility complex class I-restricted antigen of a murine colon tumor derives from an endogenous retroviral gene product. Proc Natl Acad Sci U S A (1996) 2.24
Genetic diversity of vaginal lactobacilli from women in different countries based on 16S rRNA gene sequences. J Appl Microbiol (2002) 2.22
TRAPP I implicated in the specificity of tethering in ER-to-Golgi transport. Mol Cell (2001) 2.20
Quality of life for children with fecal incontinence after surgically corrected anorectal malformation. J Pediatr Surg (2000) 2.17
Mortality and cardiovascular disease among older live kidney donors. Am J Transplant (2014) 2.16
The C3(1)/SV40 T-antigen transgenic mouse model of mammary cancer: ductal epithelial cell targeting with multistage progression to carcinoma. Oncogene (2000) 2.15
Peroxisome proliferator-activated receptor gamma ligands are potent inhibitors of angiogenesis in vitro and in vivo. J Biol Chem (1999) 2.13
The minor histocompatibility antigen HA-1: a diallelic gene with a single amino acid polymorphism. Science (1998) 2.11
Validity of the ten questions screened for childhood disability: results from population-based studies in Bangladesh, Jamaica, and Pakistan. Epidemiology (1994) 2.10
Altered hepatic lymphocyte subpopulations in obesity-related murine fatty livers: potential mechanism for sensitization to liver damage. Hepatology (2000) 2.10
Hydration of fat-free body mass: new physiological modeling approach. Am J Physiol (1999) 2.09
Non-invasive prenatal testing for trisomies 21, 18 and 13: clinical experience from 146,958 pregnancies. Ultrasound Obstet Gynecol (2015) 2.07
Extended therapy with intravenous arginine butyrate in patients with beta-hemoglobinopathies. N Engl J Med (1995) 2.05
A population-based estimate of the burden of diarrhoeal illness in the United States: FoodNet, 1996-7. Epidemiol Infect (2002) 2.03
Actinonin, a naturally occurring antibacterial agent, is a potent deformylase inhibitor. Biochemistry (2000) 2.03
Repeatability of the Pedar-X in-shoe pressure measuring system. Foot Ankle Surg (2009) 2.03
Characterization of SWI/SNF protein expression in human breast cancer cell lines and other malignancies. J Cell Physiol (2001) 2.02
Matrix metalloproteinase-2 contributes to ischemia-reperfusion injury in the heart. Circulation (2000) 2.01
A frame shift mutation in the DNA-binding domain of the androgen receptor gene associated with complete androgen insensitivity, persistent müllerian structures, and germ cell tumors in dysgenetic gonads. Fertil Steril (1999) 2.00
Cognitive functioning and brain magnetic resonance imaging in children with sickle Cell disease. Neuropsychology Committee of the Cooperative Study of Sickle Cell Disease. Pediatrics (1996) 1.98
Biliary Excretion of Cyclosporine in Liver Transplant Patients. Transplant Proc (1985) 1.98
Cigarette smoking is associated with augmented progression of renal insufficiency in severe essential hypertension. Am J Kidney Dis (2000) 1.96
The regulation of glucose-excited neurons in the hypothalamic arcuate nucleus by glucose and feeding-relevant peptides. Diabetes (2004) 1.96
Cutting edge: the orphan chemokine receptor G protein-coupled receptor-2 (GPR-2, CCR10) binds the skin-associated chemokine CCL27 (CTACK/ALP/ILC). J Immunol (2000) 1.95
Obesity induces expression of uncoupling protein-2 in hepatocytes and promotes liver ATP depletion. J Biol Chem (1999) 1.94
HEF1 is a necessary and specific downstream effector of FAK that promotes the migration of glioblastoma cells. Oncogene (2006) 1.94
The 3'-end-processing factor CPSF is required for the splicing of single-intron pre-mRNAs in vivo. RNA (2001) 1.94
Down-regulation of cyclin D1 expression by prostaglandin A(2) is mediated by enhanced cyclin D1 mRNA turnover. Mol Cell Biol (2000) 1.93
Intraocular lens power calculation after laser in situ keratomileusis for myopia and hyperopia: a standardized approach. Cornea (2001) 1.90
H36-alpha 7 is a novel integrin alpha chain that is developmentally regulated during skeletal myogenesis. J Cell Biol (1992) 1.89
Curbing the nonsense: the activation and regulation of mRNA surveillance. Genes Dev (2001) 1.87
Caspase and calpain activation both contribute to sepsis-induced diaphragmatic weakness. J Appl Physiol (1985) (2009) 1.86
Harvesting energy from the marine sediment--water interface. Environ Sci Technol (2001) 1.85
Non-invasive prenatal testing for fetal chromosomal abnormalities by low-coverage whole-genome sequencing of maternal plasma DNA: review of 1982 consecutive cases in a single center. Ultrasound Obstet Gynecol (2014) 1.85
Chemical constituents from Dendrobium densiflorum. Phytochemistry (2001) 1.82
A computational approach to simplifying the protein folding alphabet. Nat Struct Biol (1999) 1.82
Trp1, a candidate protein for the store-operated Ca(2+) influx mechanism in salivary gland cells. J Biol Chem (2000) 1.82
The EH and SH3 domain Ese proteins regulate endocytosis by linking to dynamin and Eps15. EMBO J (1999) 1.82
Physical activity, falls, and fractures among older adults: a review of the epidemiologic evidence. J Am Geriatr Soc (2000) 1.81
Evaluating a ten questions screen for childhood disability: reliability and internal structure in different cultures. J Clin Epidemiol (1995) 1.79
Novel protein kinases Ark1p and Prk1p associate with and regulate the cortical actin cytoskeleton in budding yeast. J Cell Biol (1999) 1.79
Maternal bisphenol-A levels at delivery: a looming problem? J Perinatol (2008) 1.78