Published in J Cell Sci on September 01, 2001
A microtubule-dependent zone of active RhoA during cleavage plane specification. J Cell Biol (2005) 3.15
Terminal cytokinesis events uncovered after an RNAi screen. Curr Biol (2004) 2.99
Cytokinesis in eukaryotes. Microbiol Mol Biol Rev (2002) 2.43
Chemical genetics reveals the requirement for Polo-like kinase 1 activity in positioning RhoA and triggering cytokinesis in human cells. Proc Natl Acad Sci U S A (2007) 2.37
Citron kinase, a Rho-dependent kinase, induces di-phosphorylation of regulatory light chain of myosin II. Mol Biol Cell (2003) 2.17
Mutations in sticky lead to defective organization of the contractile ring during cytokinesis and are enhanced by Rho and suppressed by Rac. J Cell Biol (2004) 1.94
Plk1 self-organization and priming phosphorylation of HsCYK-4 at the spindle midzone regulate the onset of division in human cells. PLoS Biol (2009) 1.78
Citron kinase controls abscission through RhoA and anillin. Mol Biol Cell (2011) 1.37
Nonmuscle myosin-2: mix and match. Cell Mol Life Sci (2012) 1.30
The Rho GTP exchange factor Lfc promotes spindle assembly in early mitosis. Proc Natl Acad Sci U S A (2005) 1.28
RhoA GTPase is dispensable for actomyosin regulation but is essential for mitosis in primary mouse embryonic fibroblasts. J Biol Chem (2011) 1.23
Rho GTPases regulate PRK2/PKN2 to control entry into mitosis and exit from cytokinesis. EMBO J (2007) 1.19
Rho and anillin-dependent control of mDia2 localization and function in cytokinesis. Mol Biol Cell (2010) 1.17
Defining the protein-protein interaction network of the human hippo pathway. Mol Cell Proteomics (2013) 1.14
Myosin II recruitment during cytokinesis independent of centralspindlin-mediated phosphorylation. J Biol Chem (2009) 1.07
Understanding cytokinesis failure. Adv Exp Med Biol (2010) 1.06
Pseudomonas aeruginosa type III-secreted toxin ExoT inhibits host-cell division by targeting cytokinesis at multiple steps. Proc Natl Acad Sci U S A (2006) 1.04
Sticky/Citron kinase maintains proper RhoA localization at the cleavage site during cytokinesis. J Cell Biol (2011) 1.01
Deficiency of mDia, an actin nucleator, disrupts integrity of neuroepithelium and causes periventricular dysplasia. PLoS One (2011) 0.94
Mitochondria localize to the cleavage furrow in mammalian cytokinesis. PLoS One (2013) 0.93
Deficiency in myosin light-chain phosphorylation causes cytokinesis failure and multipolarity in cancer cells. Oncogene (2010) 0.93
Opposing roles of p190RhoGAP and Ect2 RhoGEF in regulating cytokinesis. Cell Cycle (2008) 0.93
Citron kinase, a RhoA effector, enhances HIV-1 virion production by modulating exocytosis. Traffic (2006) 0.91
p27(Kip1) controls cytokinesis via the regulation of citron kinase activation. J Clin Invest (2012) 0.90
Targeting and clustering citron to synapses. Mol Cell Neurosci (2005) 0.89
Opposing actions of septins and Sticky on Anillin promote the transition from contractile to midbody ring. J Cell Biol (2013) 0.88
Biallelic Mutations in Citron Kinase Link Mitotic Cytokinesis to Human Primary Microcephaly. Am J Hum Genet (2016) 0.87
p53 dependent centrosome clustering prevents multipolar mitosis in tetraploid cells. PLoS One (2011) 0.86
Myosin light chain kinases and phosphatase in mitosis and cytokinesis. Arch Biochem Biophys (2011) 0.83
Drosophila sticky/citron kinase is a regulator of cell-cycle progression, genetically interacts with Argonaute 1 and modulates epigenetic gene silencing. Genetics (2008) 0.81
Two-pore channel 1 interacts with citron kinase, regulating completion of cytokinesis. Channels (Austin) (2015) 0.77
SHCBP1 is required for midbody organization and cytokinesis completion. Cell Cycle (2014) 0.77
E2F-2 promotes nuclear condensation and enucleation of terminally differentiated erythroblasts. Mol Cell Biol (2016) 0.76
Mutations in CIT, encoding citron rho-interacting serine/threonine kinase, cause severe primary microcephaly in humans. Hum Genet (2016) 0.76
Loss of citron kinase affects a subset of progenitor cells that alters late but not early neurogenesis in the developing rat retina. Invest Ophthalmol Vis Sci (2015) 0.75
The transcriptional landscape of the mammalian genome. Science (2005) 37.63
Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension. Nature (1997) 14.91
Occludin: a novel integral membrane protein localizing at tight junctions. J Cell Biol (1993) 10.65
Focal contacts as mechanosensors: externally applied local mechanical force induces growth of focal contacts by an mDia1-dependent and ROCK-independent mechanism. J Cell Biol (2001) 9.73
In vitro hemolytic characteristic of Vibrio parahaemolyticus: its close correlation with human pathogenicity. J Bacteriol (1969) 8.04
Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase. Science (1999) 7.12
The rate of loss of weight in skeletal muscle after nerve section with some observations on the effect of stimulation and other treatment. J Physiol (1915) 6.49
Cooperation between mDia1 and ROCK in Rho-induced actin reorganization. Nat Cell Biol (1999) 5.84
A novel ras-related gene family. Cell (1985) 5.81
Isolation and characterization of mutants of Escherichia coli deficient in induction of mutations by ultraviolet light. Mol Gen Genet (1977) 5.61
Development of a novel form of an oral 5-fluorouracil derivative (S-1) directed to the potentiation of the tumor selective cytotoxicity of 5-fluorouracil by two biochemical modulators. Anticancer Drugs (1996) 5.45
Impaired glucose tolerance is a risk factor for cardiovascular disease, but not impaired fasting glucose. The Funagata Diabetes Study. Diabetes Care (1999) 5.37
Studies on the enteropathogenic, facultatively halophilic bacterium, Vibrio parahaemolyticus. 3. Enteropathogenicity. Jpn J Med Sci Biol (1968) 5.35
AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1. Nat Genet (2000) 5.26
Primary structure and functional expression of the cardiac dihydropyridine-sensitive calcium channel. Nature (1989) 5.21
Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association. J Cell Biol (1998) 5.15
International Union of Pharmacology classification of prostanoid receptors: properties, distribution, and structure of the receptors and their subtypes. Pharmacol Rev (1994) 5.11
The small GTP-binding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinase. EMBO J (1996) 5.09
p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin. EMBO J (1997) 5.03
Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions. J Cell Biol (1994) 5.01
Complete genome structure of the nitrogen-fixing symbiotic bacterium Mesorhizobium loti. DNA Res (2000) 4.94
Pharmacological properties of Y-27632, a specific inhibitor of rho-associated kinases. Mol Pharmacol (2000) 4.80
Identification of CRE1 as a cytokinin receptor from Arabidopsis. Nature (2001) 4.77
Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development. Cell (1993) 4.46
The physiological action of physostigmine and its action on denervated skeletal muscle. J Physiol (1915) 4.37
p160ROCK, a Rho-associated coiled-coil forming protein kinase, works downstream of Rho and induces focal adhesions. FEBS Lett (1997) 4.31
The 220-kD protein colocalizing with cadherins in non-epithelial cells is identical to ZO-1, a tight junction-associated protein in epithelial cells: cDNA cloning and immunoelectron microscopy. J Cell Biol (1993) 4.22
The mammalian G protein rhoC is ADP-ribosylated by Clostridium botulinum exoenzyme C3 and affects actin microfilaments in Vero cells. EMBO J (1989) 4.21
The c-mos proto-oncogene product is a cytostatic factor responsible for meiotic arrest in vertebrate eggs. Nature (1989) 4.13
RecA protein-dependent cleavage of UmuD protein and SOS mutagenesis. Proc Natl Acad Sci U S A (1988) 4.12
A novel method for phosphorylation of nucleosides to 5'-nucleotides. Tetrahedron Lett (1967) 4.11
Regulation mechanism of ERM (ezrin/radixin/moesin) protein/plasma membrane association: possible involvement of phosphatidylinositol turnover and Rho-dependent signaling pathway. J Cell Biol (1996) 4.06
Arabidopsis NPL1: a phototropin homolog controlling the chloroplast high-light avoidance response. Science (2001) 3.93
Regulation of drought tolerance by gene manipulation of 9-cis-epoxycarotenoid dioxygenase, a key enzyme in abscisic acid biosynthesis in Arabidopsis. Plant J (2001) 3.92
Discrimination between Alzheimer dementia and controls by automated analysis of multicenter FDG PET. Neuroimage (2002) 3.88
An essential part for Rho-associated kinase in the transcellular invasion of tumor cells. Nat Med (1999) 3.76
Inhibition of lysophosphatidate- and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho. J Cell Biol (1994) 3.65
Molecular linkage between cadherins and actin filaments in cell-cell adherens junctions. Curr Opin Cell Biol (1992) 3.61
Role of citron kinase as a target of the small GTPase Rho in cytokinesis. Nature (1998) 3.55
Characterization of two members of the rho gene family from the yeast Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1987) 3.50
Asparagine residue in the rho gene product is the modification site for botulinum ADP-ribosyltransferase. J Biol Chem (1989) 3.47
ROCK-I and ROCK-II, two isoforms of Rho-associated coiled-coil forming protein serine/threonine kinase in mice. FEBS Lett (1996) 3.46
A 220-kD undercoat-constitutive protein: its specific localization at cadherin-based cell-cell adhesion sites. J Cell Biol (1991) 3.31
Corneal neovascularization. Curr Opin Ophthalmol (2001) 3.22
Prostaglandin D2 as a mediator of allergic asthma. Science (2000) 3.19
Genome-wide analysis of gene expression in human hepatocellular carcinomas using cDNA microarray: identification of genes involved in viral carcinogenesis and tumor progression. Cancer Res (2001) 3.18
Determination of the ID50 values of antibacterial agents in agar. J Antibiot (Tokyo) (1978) 3.08
Safe right subclavian vein puncture: the importance of pressing the skin with the left thumb. Am J Emerg Med (1993) 3.07
Altered pain perception and inflammatory response in mice lacking prostacyclin receptor. Nature (1997) 3.07
Base-change mutagenesis and prophage induction in strains of Escherichia coli with different DNA repair capacities. Genetics (1970) 3.05
A gene family consisting of ezrin, radixin and moesin. Its specific localization at actin filament/plasma membrane association sites. J Cell Sci (1992) 3.04
Clostridium perfringens enterotoxin fragment removes specific claudins from tight junction strands: Evidence for direct involvement of claudins in tight junction barrier. J Cell Biol (1999) 3.02
Protein kinase N (PKN) and PKN-related protein rhophilin as targets of small GTPase Rho. Science (1996) 2.99
Rho-associated kinase ROCK activates LIM-kinase 1 by phosphorylation at threonine 508 within the activation loop. J Biol Chem (2000) 2.99
Acceleration of intestinal polyposis through prostaglandin receptor EP2 in Apc(Delta 716) knockout mice. Nat Med (2001) 2.98
Interspecies diversity of the occludin sequence: cDNA cloning of human, mouse, dog, and rat-kangaroo homologues. J Cell Biol (1996) 2.94
cDNA cloning and structure of mouse putative Ah receptor. Biochem Biophys Res Commun (1992) 2.93
Perturbation of cell adhesion and microvilli formation by antisense oligonucleotides to ERM family members. J Cell Biol (1994) 2.93
Rhotekin, a new putative target for Rho bearing homology to a serine/threonine kinase, PKN, and rhophilin in the rho-binding domain. J Biol Chem (1996) 2.92
Alternative splicing of C-terminal tail of prostaglandin E receptor subtype EP3 determines G-protein specificity. Nature (1993) 2.91
Analysis and typing of the vacA gene from cagA-positive strains of Helicobacter pylori isolated in Japan. J Clin Microbiol (1997) 2.89
Impaired febrile response in mice lacking the prostaglandin E receptor subtype EP3. Nature (1998) 2.88
Submembranous junctional plaque proteins include potential tumor suppressor molecules. J Cell Biol (1993) 2.87
Molecular dissection of the Rho-associated protein kinase (p160ROCK)-regulated neurite remodeling in neuroblastoma N1E-115 cells. J Cell Biol (1998) 2.81
Development of atopic dermatitis-like skin lesion with IgE hyperproduction in NC/Nga mice. Int Immunol (1997) 2.79
PKA and MPF-activated polo-like kinase regulate anaphase-promoting complex activity and mitosis progression. Mol Cell (1998) 2.75
A novel negative selection for homologous recombinants using diphtheria toxin A fragment gene. Anal Biochem (1993) 2.74
A rho-like protein is involved in the organisation of the contractile ring in dividing sand dollar eggs. Zygote (1993) 2.71
Preoperative probability model for predicting overall survival after resection of pulmonary metastases from colorectal cancer. Br J Surg (2004) 2.62
Cortical actin organization: lessons from ERM (ezrin/radixin/moesin) proteins. J Biol Chem (1999) 2.60
Hyperammonaemia and Helicobacter pylori. Lancet (1995) 2.59
Tumor angiogenesis in human lung adenocarcinoma. Cancer (1994) 2.59
A novel partner for the GTP-bound forms of rho and rac. FEBS Lett (1995) 2.52
Structural and mechanistic insights into the interaction between Rho and mammalian Dia. Nature (2005) 2.52
ARR1, a transcription factor for genes immediately responsive to cytokinins. Science (2001) 2.50
Can endoscopic papillary balloon dilation really preserve sphincter of Oddi function? Gut (2001) 2.49
Overexpression of the rhoC gene correlates with progression of ductal adenocarcinoma of the pancreas. Br J Cancer (1998) 2.48