Published in Genes Dev on October 15, 2001
Cardiomyocyte GATA4 functions as a stress-responsive regulator of angiogenesis in the murine heart. J Clin Invest (2007) 2.12
Essential role of GATA-4 in cell survival and drug-induced cardiotoxicity. Proc Natl Acad Sci U S A (2004) 2.07
Re-employment of developmental transcription factors in adult heart disease. Semin Cell Dev Biol (2006) 1.82
Role of the GATA family of transcription factors in endocrine development, function, and disease. Mol Endocrinol (2008) 1.81
The transcriptional coactivator FHL2 transmits Rho signals from the cell membrane into the nucleus. EMBO J (2002) 1.72
Repression of c-kit and its downstream substrates by GATA-1 inhibits cell proliferation during erythroid maturation. Mol Cell Biol (2005) 1.67
Atrial natriuretic peptide suppresses endothelin gene expression and proliferation in cardiac fibroblasts through a GATA4-dependent mechanism. Cardiovasc Res (2009) 1.65
Transcription factor GATA4 inhibits doxorubicin-induced autophagy and cardiomyocyte death. J Biol Chem (2009) 1.52
Activation of RhoA in podocytes induces focal segmental glomerulosclerosis. J Am Soc Nephrol (2011) 1.44
Air pollution and cardiac remodeling: a role for RhoA/Rho-kinase. Am J Physiol Heart Circ Physiol (2009) 1.44
The A-kinase anchoring protein (AKAP)-Lbc-signaling complex mediates alpha1 adrenergic receptor-induced cardiomyocyte hypertrophy. Proc Natl Acad Sci U S A (2007) 1.34
Endothelin-1 gene regulation. FASEB J (2010) 1.32
The transcription factor GATA-6 regulates pathological cardiac hypertrophy. Circ Res (2010) 1.32
Maternal cocaine administration in mice alters DNA methylation and gene expression in hippocampal neurons of neonatal and prepubertal offspring. PLoS One (2008) 1.32
A novel inducible transactivation domain in the androgen receptor: implications for PRK in prostate cancer. EMBO J (2003) 1.32
The Kruppel-like transcription factor KLF13 is a novel regulator of heart development. EMBO J (2006) 1.25
Serine 105 phosphorylation of transcription factor GATA4 is necessary for stress-induced cardiac hypertrophy in vivo. Proc Natl Acad Sci U S A (2011) 1.23
Human CNK1 acts as a scaffold protein, linking Rho and Ras signal transduction pathways. Mol Cell Biol (2004) 1.21
Cardiac growth and angiogenesis coordinated by intertissue interactions. J Clin Invest (2007) 1.18
GATA- and Smad1-dependent enhancers in the Smad7 gene differentially interpret bone morphogenetic protein concentrations. Mol Cell Biol (2003) 1.15
Loss of mitogen-activated protein kinase kinase kinase 4 (MAP3K4) reveals a requirement for MAPK signalling in mouse sex determination. PLoS Biol (2009) 1.10
Convergence of protein kinase C and JAK-STAT signaling on transcription factor GATA-4. Mol Cell Biol (2005) 1.09
Regulation of calcineurin through transcriptional induction of the calcineurin A beta promoter in vitro and in vivo. Mol Cell Biol (2005) 1.06
LIM-only protein, CRP2, switched on smooth muscle gene activity in adult cardiac myocytes. Proc Natl Acad Sci U S A (2006) 1.06
PKA, Rap1, ERK1/2, and p90RSK mediate PGE2 and EP4 signaling in neonatal ventricular myocytes. Am J Physiol Heart Circ Physiol (2009) 1.01
GATA6 promotes colon cancer cell invasion by regulating urokinase plasminogen activator gene expression. Neoplasia (2010) 1.01
A-kinase anchoring protein (AKAP)-Lbc anchors a PKN-based signaling complex involved in α1-adrenergic receptor-induced p38 activation. J Biol Chem (2011) 0.99
Disruption of a GATA4/Ankrd1 signaling axis in cardiomyocytes leads to sarcomere disarray: implications for anthracycline cardiomyopathy. PLoS One (2012) 0.99
The Rho guanine nucleotide exchange factor AKAP13 (BRX) is essential for cardiac development in mice. J Biol Chem (2010) 0.97
Cell signaling pathways for the regulation of GATA4 transcription factor: Implications for cell growth and apoptosis. Cell Signal (2011) 0.96
Cardioprotection of controlled and cardiac-specific over-expression of A(2A)-adenosine receptor in the pressure overload. PLoS One (2012) 0.95
Gadd45γ and Map3k4 interactions regulate mouse testis determination via p38 MAPK-mediated control of Sry expression. Dev Cell (2012) 0.94
Partial loss of GATA factor Pannier impairs adult heart function in Drosophila. Hum Mol Genet (2009) 0.93
Genetic analysis of specific and redundant roles for p38alpha and p38beta MAPKs during mouse development. Proc Natl Acad Sci U S A (2011) 0.93
Molecular role of GATA binding protein 4 (GATA-4) in hyperglycemia-induced reduction of cardiac contractility. Cardiovasc Diabetol (2011) 0.92
Cyclin D2 rescues size and function of GATA4 haplo-insufficient hearts. Am J Physiol Heart Circ Physiol (2012) 0.90
Dissociation of cardiogenic and postnatal myocardial activities of GATA4. Mol Cell Biol (2012) 0.88
STAT5a activation mediates the epithelial to mesenchymal transition induced by oncogenic RhoA. Mol Biol Cell (2003) 0.87
Promyelocytic leukemia zinc finger protein activates GATA4 transcription and mediates cardiac hypertrophic signaling from angiotensin II receptor 2. PLoS One (2012) 0.87
Cyclin D2 is a GATA4 cofactor in cardiogenesis. Proc Natl Acad Sci U S A (2014) 0.86
Transcription factors in heart: promising therapeutic targets in cardiac hypertrophy. Curr Cardiol Rev (2011) 0.86
The zinc finger-only protein Zfp260 is a novel cardiac regulator and a nuclear effector of alpha1-adrenergic signaling. Mol Cell Biol (2005) 0.85
Cardiac expression of ms1/STARS, a novel gene involved in cardiac development and disease, is regulated by GATA4. Mol Cell Biol (2012) 0.85
Targeted inhibition of ANKRD1 disrupts sarcomeric ERK-GATA4 signal transduction and abrogates phenylephrine-induced cardiomyocyte hypertrophy. Cardiovasc Res (2015) 0.84
GATA4 is a survival factor in adult cardiac myocytes but is not required for alpha1A-adrenergic receptor survival signaling. Am J Physiol Heart Circ Physiol (2008) 0.84
Transcriptional networks regulating the costamere, sarcomere, and other cytoskeletal structures in striated muscle. Cell Mol Life Sci (2013) 0.83
A-kinase anchoring proteins that regulate cardiac remodeling. J Cardiovasc Pharmacol (2011) 0.83
GATA4 regulates osteoblastic differentiation and bone remodeling via p38-mediated signaling. J Mol Histol (2017) 0.82
PIAS1 is a GATA4 SUMO ligase that regulates GATA4-dependent intestinal promoters independent of SUMO ligase activity and GATA4 sumoylation. PLoS One (2012) 0.82
Inhibition of cardiomyocyte hypertrophy by protein arginine methyltransferase 5. J Biol Chem (2014) 0.81
Caspase-1 cleavage of transcription factor GATA4 and regulation of cardiac cell fate. Cell Death Dis (2014) 0.81
GATA4 regulates ANF expression synergistically with Sp1 in a cardiac hypertrophy model. J Cell Mol Med (2011) 0.80
A-kinase anchoring protein Lbc coordinates a p38 activating signaling complex controlling compensatory cardiac hypertrophy. Mol Cell Biol (2013) 0.79
The junctional proteins cingulin and paracingulin modulate the expression of tight junction protein genes through GATA-4. PLoS One (2013) 0.79
Natriuretic Peptides in the Regulation of Cardiovascular Physiology and Metabolic Events. J Am Heart Assoc (2015) 0.78
Carboxy terminus of GATA4 transcription factor is required for its cardiogenic activity and interaction with CDK4. Mech Dev (2014) 0.78
Downregulation in GATA4 and Downstream Structural and Contractile Genes in the db/db Mouse Heart. ISRN Endocrinol (2012) 0.78
Low-dose radiation affects cardiac physiology: gene networks and molecular signaling in cardiomyocytes. Am J Physiol Heart Circ Physiol (2015) 0.78
Gene Expression Profiling of H9c2 Myoblast Differentiation towards a Cardiac-Like Phenotype. PLoS One (2015) 0.77
Cardiac-restricted Overexpression of TRAF3 Interacting Protein 2 (TRAF3IP2) Results in Spontaneous Development of Myocardial Hypertrophy, Fibrosis, and Dysfunction. J Biol Chem (2016) 0.77
RhoA-ROCK signaling is involved in contraction-mediated inhibition of SERCA2a expression in cardiomyocytes. Pflugers Arch (2009) 0.77
ZFP260 is an inducer of cardiac hypertrophy and a nuclear mediator of endothelin-1 signaling. J Biol Chem (2010) 0.77
Novel exons in the tbx5 gene locus generate protein isoforms with distinct expression domains and function. J Biol Chem (2015) 0.77
NEXN inhibits GATA4 and leads to atrial septal defects in mice and humans. Cardiovasc Res (2014) 0.76
Nuclear Receptor-Like Structure and Interaction of Congenital Heart Disease-Associated Factors GATA4 and NKX2-5. PLoS One (2015) 0.75
Art27 interacts with GATA4, FOG2 and NKX2.5 and is a novel co-repressor of cardiac genes. PLoS One (2014) 0.75
Investigation of association between PFO complicated by cryptogenic stroke and a common variant of the cardiac transcription factor GATA4. PLoS One (2011) 0.75
Rho GTPase signaling promotes constitutive expression and release of TGF-β2 by human trabecular meshwork cells. Exp Eye Res (2015) 0.75
Mesenchymal stem cells from umbilical cord tissue as potential therapeutics for cardiomyodegenerative diseases - a review. Int J Mol Cell Med (2012) 0.75
IRAK4 deficiency promotes cardiac remodeling induced by pressure overload. Int J Clin Exp Med (2015) 0.75
Cardiac Myocyte p38α Kinase Regulates Angiogenesis via Myocyte-Endothelial Cell Cross-talk During Stress-Induced Remodeling in Heart. J Biol Chem (2017) 0.75
Rho GTPases and the actin cytoskeleton. Science (1998) 28.19
Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase) Science (1996) 15.88
A gas-liquid solid phase peptide and protein sequenator. J Biol Chem (1981) 15.73
Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension. Nature (1997) 14.91
Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton. EMBO J (1999) 9.76
Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs. Cell (1995) 9.30
The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF. Cell (1995) 8.20
Defects in mesoderm, neural tube and vascular development in mouse embryos lacking fibronectin. Development (1993) 6.56
Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis. Genes Dev (1997) 6.52
Cooperation between mDia1 and ROCK in Rho-induced actin reorganization. Nat Cell Biol (1999) 5.84
GATA4 transcription factor is required for ventral morphogenesis and heart tube formation. Genes Dev (1997) 5.51
The genetic basis for cardiomyopathy: from mutation identification to mechanistic paradigms. Cell (2001) 5.35
Bni1p, a yeast formin linking cdc42p and the actin cytoskeleton during polarized morphogenesis. Science (1997) 5.27
Signal-regulated activation of serum response factor is mediated by changes in actin dynamics. Cell (1999) 4.52
Improvement of an "In-Gel" digestion procedure for the micropreparation of internal protein fragments for amino acid sequencing. Anal Biochem (1995) 4.49
Manipulation of adenovirus vectors. Methods Mol Biol (1991) 4.31
Mutations in sarcomere protein genes as a cause of dilated cardiomyopathy. N Engl J Med (2000) 4.30
Ras and Rho GTPases: a family reunion. Cell (2000) 4.21
Cytoplasmic signaling pathways that regulate cardiac hypertrophy. Annu Rev Physiol (2001) 4.17
Signaling pathways for cardiac hypertrophy and failure. N Engl J Med (1999) 3.97
Cardiac muscle cell hypertrophy and apoptosis induced by distinct members of the p38 mitogen-activated protein kinase family. J Biol Chem (1998) 3.80
Actin-dependent localization of an RNA encoding a cell-fate determinant in yeast. Nature (1997) 3.49
The cardiac transcription factors Nkx2-5 and GATA-4 are mutual cofactors. EMBO J (1997) 3.35
Activation of the nuclear factor-kappaB by Rho, CDC42, and Rac-1 proteins. Genes Dev (1997) 3.23
Rho-associated kinase directly induces smooth muscle contraction through myosin light chain phosphorylation. J Biol Chem (1997) 3.12
Diaphanous-related formins bridge Rho GTPase and Src tyrosine kinase signaling. Mol Cell (2000) 2.95
Involvement of rho p21 in the GTP-enhanced calcium ion sensitivity of smooth muscle contraction. J Biol Chem (1992) 2.90
GATA-dependent recruitment of MEF2 proteins to target promoters. EMBO J (2000) 2.79
Transcription factor GATA-4 regulates cardiac muscle-specific expression of the alpha-myosin heavy-chain gene. Mol Cell Biol (1994) 2.63
cis-Acting sequences that mediate induction of beta-myosin heavy chain gene expression during left ventricular hypertrophy due to aortic constriction. Circulation (1997) 2.54
The transcription factors GATA4 and GATA6 regulate cardiomyocyte hypertrophy in vitro and in vivo. J Biol Chem (2001) 2.50
RhoA effector mutants reveal distinct effector pathways for cytoskeletal reorganization, SRF activation and transformation. EMBO J (1998) 2.22
A role for the p38 mitogen-activated protein kinase pathway in myocardial cell growth, sarcomeric organization, and cardiac-specific gene expression. J Cell Biol (1997) 2.19
A hormone-encoding gene identifies a pathway for cardiac but not skeletal muscle gene transcription. Mol Cell Biol (1994) 2.15
Fibronectins are essential for heart and blood vessel morphogenesis but are dispensable for initial specification of precursor cells. Blood (1997) 2.15
Enhanced cardiogenesis in embryonic stem cells overexpressing the GATA-4 transcription factor. Development (1997) 2.07
GATA-4 and Nkx-2.5 coactivate Nkx-2 DNA binding targets: role for regulating early cardiac gene expression. Mol Cell Biol (1998) 2.00
Cooperative interaction between GATA-4 and GATA-6 regulates myocardial gene expression. Mol Cell Biol (1999) 1.95
T cell activation and the cytoskeleton. Annu Rev Immunol (2000) 1.94
Stimulation of the p38 mitogen-activated protein kinase pathway in neonatal rat ventricular myocytes by the G protein-coupled receptor agonists, endothelin-1 and phenylephrine: a role in cardiac myocyte hypertrophy? J Cell Biol (1998) 1.92
Role of guanine nucleotide-binding proteins--ras-family or trimeric proteins or both--in Ca2+ sensitization of smooth muscle. Proc Natl Acad Sci U S A (1996) 1.87
Transcriptional regulation of T lymphocyte development and function. Annu Rev Immunol (1999) 1.86
Involvement of the small GTPase rho in integrin-mediated activation of mitogen-activated protein kinase. J Biol Chem (1996) 1.82
Cardiac-specific overexpression of RhoA results in sinus and atrioventricular nodal dysfunction and contractile failure. J Clin Invest (1999) 1.82
Signaling networks linking integrins and rho family GTPases. Trends Biochem Sci (2000) 1.81
GATA transcription factors and cardiac development. Semin Cell Dev Biol (1999) 1.81
A network of mitogen-activated protein kinases links G protein-coupled receptors to the c-jun promoter: a role for c-Jun NH2-terminal kinase, p38s, and extracellular signal-regulated kinase 5. Mol Cell Biol (1999) 1.75
The GATA-4 transcription factor transactivates the cardiac muscle-specific troponin C promoter-enhancer in nonmuscle cells. Mol Cell Biol (1994) 1.70
Mutations in the Rho1 small GTPase disrupt morphogenesis and segmentation during early Drosophila development. Development (1999) 1.69
The atrial natriuretic factor promoter is a downstream target for Nkx-2.5 in the myocardium. Mol Cell Biol (1996) 1.67
MAP kinase- and Rho-dependent signals interact to regulate gene expression but not actin morphology in cardiac muscle cells. EMBO J (1997) 1.66
Opposing effects of Jun kinase and p38 mitogen-activated protein kinases on cardiomyocyte hypertrophy. Mol Cell Biol (1998) 1.63
Transcription factor GATA-4 is expressed in a sexually dimorphic pattern during mouse gonadal development and is a potent activator of the Müllerian inhibiting substance promoter. Development (1998) 1.60
Angiotensin II type1a receptor gene expression in the heart: AP-1 and GATA-4 participate in the response to pressure overload. Proc Natl Acad Sci U S A (1997) 1.56
Rho is required for Galphaq and alpha1-adrenergic receptor signaling in cardiomyocytes. Dissociation of Ras and Rho pathways. J Biol Chem (1996) 1.48
The Rho family G proteins play a critical role in muscle differentiation. Mol Cell Biol (1998) 1.47
Angiotensin II activates RhoA in cardiac myocytes: a critical role of RhoA in angiotensin II-induced premyofibril formation. Circ Res (1998) 1.46
Regulation of gene expression by the small GTPase Rho through the ERK6 (p38 gamma) MAP kinase pathway. Genes Dev (2001) 1.41
The low molecular weight GTPase Rho regulates myofibril formation and organization in neonatal rat ventricular myocytes. Involvement of Rho kinase. J Biol Chem (1998) 1.40
Developmental stage-specific regulation of atrial natriuretic factor gene transcription in cardiac cells. Mol Cell Biol (1994) 1.30
Ash1, a daughter cell-specific protein, is required for pseudohyphal growth of Saccharomyces cerevisiae. Mol Cell Biol (1998) 1.29
The human GATA-6 gene: structure, chromosomal location, and regulation of expression by tissue-specific and mitogen-responsive signals. Genomics (1996) 1.25
Percutaneous transluminal in vivo gene transfer by recombinant adenovirus in normal porcine coronary arteries, atherosclerotic arteries, and two models of coronary restenosis. Circulation (1994) 1.23
Phosphorylation of GATA-4 is involved in alpha 1-adrenergic agonist-responsive transcription of the endothelin-1 gene in cardiac myocytes. J Biol Chem (2000) 1.23
The stress inducer arsenite activates mitogen-activated protein kinases extracellular signal-regulated kinases 1 and 2 via a MAPK kinase 6/p38-dependent pathway. J Biol Chem (1998) 1.21
Involvement of the small GTPases XRhoA and XRnd1 in cell adhesion and head formation in early Xenopus development. Development (1999) 1.21
Small guanine nucleotide-binding proteins and myocardial hypertrophy. Circ Res (2000) 1.18
Serum response factor-GATA ternary complex required for nuclear signaling by a G-protein-coupled receptor. Mol Cell Biol (2001) 1.14
p38 MAP kinase pathway regulates angiotensin II-induced contraction of rat vascular smooth muscle. Am J Physiol Heart Circ Physiol (2000) 1.10
Regulation of SRF activity by Rho family GTPases. Cold Spring Harb Symp Quant Biol (1998) 1.10
Hsp25 and the p38 MAPK pathway are involved in differentiation of cardiomyocytes. Dev Biol (2000) 1.09
Cytoprotection by Jun kinase during nitric oxide-induced cardiac myocyte apoptosis. Circ Res (2001) 1.08
Regulation of mitogen-activated protein kinases in cardiac myocytes through the small G protein Rac1. Mol Cell Biol (2001) 1.07
Effector domain mutants of Rho dissociate cytoskeletal changes from nuclear signaling and cellular transformation. Oncogene (1998) 1.04
Regulation of the rat cardiac troponin I gene by the transcription factor GATA-4. Biochem J (1997) 1.02
The small GTP-binding protein Rho potentiates AP-1 transcription in T cells. Mol Cell Biol (1998) 1.02
Functional analysis and chromosomal mapping of Gata5, a gene encoding a zinc finger DNA-binding protein. Mamm Genome (1999) 1.01
The C-terminal domain of c-fos is required for activation of an AP-1 site specific for jun-fos heterodimers. Mol Cell Biol (1998) 0.99
A positive GATA element and a negative vitamin D receptor-like element control atrial chamber-specific expression of a slow myosin heavy-chain gene during cardiac morphogenesis. Mol Cell Biol (1998) 0.88
Repression of mitogen-activated protein kinases ERK1/ERK2 activity by a protein tyrosine phosphatase in rat fibroblasts transformed by upstream oncoproteins. J Cell Physiol (1998) 0.86
Drosophila grain encodes a GATA transcription factor required for cell rearrangement during morphogenesis. Development (2000) 0.85
Temporally regulated and tissue-specific gene manipulations in the adult and embryonic heart using a tamoxifen-inducible Cre protein. Circ Res (2001) 6.15
A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease. Cell (2001) 5.77
Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation. Proc Natl Acad Sci U S A (1993) 4.53
The MEK1-ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice. EMBO J (2000) 4.09
The pronatriodilatin gene is located on the distal short arm of human chromosome 1 and on mouse chromosome 4. Am J Hum Genet (1985) 4.01
The cardiac transcription factors Nkx2-5 and GATA-4 are mutual cofactors. EMBO J (1997) 3.35
A mutant herpes simplex virus type 1 thymidine kinase reporter gene shows improved sensitivity for imaging reporter gene expression with positron emission tomography. Proc Natl Acad Sci U S A (2000) 3.28
An evaluation of home visiting of patients by physicians in geriatric medicine. Br Med J (Clin Res Ed) (1981) 3.04
Roles of the Candida albicans mitogen-activated protein kinase homolog, Cek1p, in hyphal development and systemic candidiasis. Infect Immun (1998) 2.98
GATA-dependent recruitment of MEF2 proteins to target promoters. EMBO J (2000) 2.79
Differential activation of signal transduction pathways in human hearts with hypertrophy versus advanced heart failure. Circulation (2001) 2.76
The transcription factors GATA4 and GATA6 regulate cardiomyocyte hypertrophy in vitro and in vivo. J Biol Chem (2001) 2.50
Targeted inhibition of calcineurin prevents agonist-induced cardiomyocyte hypertrophy. Proc Natl Acad Sci U S A (2000) 2.47
Prevention of cardiac hypertrophy by calcineurin inhibition: hope or hype? Circ Res (1999) 2.47
p27 cytoplasmic localization is regulated by phosphorylation on Ser10 and is not a prerequisite for its proteolysis. EMBO J (2001) 2.45
Calcineurin and human heart failure. Nat Med (1999) 2.41
Gene structure of human cardiac hormone precursor, pronatriodilatin. Nature (1985) 2.41
Glycogen synthase kinase-3beta is a negative regulator of cardiomyocyte hypertrophy. J Cell Biol (2000) 2.40
Prevention of cardiac hypertrophy in mice by calcineurin inhibition. Science (1998) 2.39
Proper coronary vascular development and heart morphogenesis depend on interaction of GATA-4 with FOG cofactors. Genes Dev (2001) 2.32
Phase I clinical trial of i.v. ascorbic acid in advanced malignancy. Ann Oncol (2008) 2.27
Modulation of gene expression by calreticulin binding to the glucocorticoid receptor. Nature (1994) 2.24
A calcineurin-NFATc3-dependent pathway regulates skeletal muscle differentiation and slow myosin heavy-chain expression. Mol Cell Biol (2000) 2.16
A hormone-encoding gene identifies a pathway for cardiac but not skeletal muscle gene transcription. Mol Cell Biol (1994) 2.15
Calcineurin promotes protein kinase C and c-Jun NH2-terminal kinase activation in the heart. Cross-talk between cardiac hypertrophic signaling pathways. J Biol Chem (2000) 2.12
The transcription factor GATA4 is activated by extracellular signal-regulated kinase 1- and 2-mediated phosphorylation of serine 105 in cardiomyocytes. Mol Cell Biol (2001) 2.10
Enhanced cardiogenesis in embryonic stem cells overexpressing the GATA-4 transcription factor. Development (1997) 2.07
GATA-4 and Nkx-2.5 coactivate Nkx-2 DNA binding targets: role for regulating early cardiac gene expression. Mol Cell Biol (1998) 2.00
Divergent transcriptional responses to independent genetic causes of cardiac hypertrophy. Physiol Genomics (2001) 1.98
A series of mutations in the D-MEF2 transcription factor reveal multiple functions in larval and adult myogenesis in Drosophila. Dev Biol (1995) 1.98
Cooperative interaction between GATA-4 and GATA-6 regulates myocardial gene expression. Mol Cell Biol (1999) 1.95
Targeted inhibition of calcineurin attenuates cardiac hypertrophy in vivo. Proc Natl Acad Sci U S A (2001) 1.94
Overexpression of angiotensin II type I receptor in cardiomyocytes induces cardiac hypertrophy and remodeling. Proc Natl Acad Sci U S A (2000) 1.93
Phosphorylation of IkappaBalpha in the C-terminal PEST domain by casein kinase II affects intrinsic protein stability. Mol Cell Biol (1996) 1.90
Calcineurin-mediated hypertrophy protects cardiomyocytes from apoptosis in vitro and in vivo: An apoptosis-independent model of dilated heart failure. Circ Res (2000) 1.82
Multiple roles for the MyoD basic region in transmission of transcriptional activation signals and interaction with MEF2. Mol Cell Biol (1998) 1.82
GATA transcription factors and cardiac development. Semin Cell Dev Biol (1999) 1.81
Periostin facilitates eosinophil tissue infiltration in allergic lung and esophageal responses. Mucosal Immunol (2008) 1.79
The atrial natriuretic factor promoter is a downstream target for Nkx-2.5 in the myocardium. Mol Cell Biol (1996) 1.67
Methylated blocked 5' terminal sequences of sea urchin embryo messenger RNA classes containing and lacking poly(A). Cell (1976) 1.65
Glucocorticoid receptor binding to a specific DNA sequence is required for hormone-dependent repression of pro-opiomelanocortin gene transcription. Mol Cell Biol (1989) 1.65
Novel glucocorticoid receptor complex with DNA element of the hormone-repressed POMC gene. EMBO J (1993) 1.63
Activated notch inhibits myogenic activity of the MADS-Box transcription factor myocyte enhancer factor 2C. Mol Cell Biol (1999) 1.61
Transcription factor GATA-4 is expressed in a sexually dimorphic pattern during mouse gonadal development and is a potent activator of the Müllerian inhibiting substance promoter. Development (1998) 1.60
Cardiac tissue enriched factors serum response factor and GATA-4 are mutual coregulators. Mol Cell Biol (2000) 1.59
A new automated computerized analyzing system simplifies readings and reduces the variability in ultrasound measurement of intima-media thickness. Stroke (1997) 1.59
Angiotensin II type1a receptor gene expression in the heart: AP-1 and GATA-4 participate in the response to pressure overload. Proc Natl Acad Sci U S A (1997) 1.56
Mutational analysis of the interaction between CD4 and class II MHC: class II antigens contact CD4 on a surface opposite the gp120-binding site. Cell (1991) 1.53
Heregulin selectively upregulates vascular endothelial growth factor secretion in cancer cells and stimulates angiogenesis. Oncogene (2000) 1.50
Messenger RNA in early sea-urchin embryos: cytoplasmic particles. Science (1965) 1.49
Derepressed hyphal growth and reduced virulence in a VH1 family-related protein phosphatase mutant of the human pathogen Candida albicans. Mol Biol Cell (1997) 1.45
Calcineurin expression, activation, and function in cardiac pressure-overload hypertrophy. Circulation (2000) 1.44
The dual-specificity phosphatase MKP-1 limits the cardiac hypertrophic response in vitro and in vivo. Circ Res (2001) 1.43
Human immunodeficiency virus gp120 and derived peptides activate protein tyrosine kinase p56lck in human CD4 T lymphocytes. Eur J Immunol (1993) 1.42
Hypertrophic defect unmasked by calcineurin expression in asymptomatic tropomodulin overexpressing transgenic mice. Cardiovasc Res (2000) 1.42
Differential regulation of p27(Kip1) expression by mitogenic and hypertrophic factors: Involvement of transcriptional and posttranscriptional mechanisms. J Cell Biol (2000) 1.40
Recurrent chromosome alterations in hepatocellular carcinoma detected by comparative genomic hybridization. Genes Chromosomes Cancer (2000) 1.39
Molecular classes of heterogeneous nuclear RNA in sea urchin embryos. J Mol Biol (1975) 1.39
Sea urchin metallothionein sequence: key to an evolutionary diversity. Proc Natl Acad Sci U S A (1985) 1.37
Expression of HGF, KGF, EGF and receptor messenger RNAs following corneal epithelial wounding. Exp Eye Res (1999) 1.36
Co-existence of non-histone messenger RNA species lacking and containing polyadenylic acid in sea urchin embryos. J Mol Biol (1974) 1.35
Regulation of MEF2 by p38 MAPK and its implication in cardiomyocyte biology. Trends Cardiovasc Med (2000) 1.35
Apoptosis in the cornea: further characterization of Fas/Fas ligand system. Exp Eye Res (1997) 1.32
Developmental stage-specific regulation of atrial natriuretic factor gene transcription in cardiac cells. Mol Cell Biol (1994) 1.30
The Fas-Fas ligand system and other modulators of apoptosis in the cornea. Invest Ophthalmol Vis Sci (1996) 1.30
Inhibition of transcription factor GATA-4 expression blocks in vitro cardiac muscle differentiation. Mol Cell Biol (1995) 1.30
The zinc finger proteins Pannier and GATA4 function as cardiogenic factors in Drosophila. Development (1999) 1.28
Inhibition of growth factor-induced protein synthesis by a selective MEK inhibitor in aortic smooth muscle cells. J Biol Chem (1996) 1.27
Molecular cloning and characterization of DNA sequences encoding rat and human atrial natriuretic factors. Proc Natl Acad Sci U S A (1984) 1.26
The gene for rat atrial natriuretic factor. J Biol Chem (1985) 1.25
Control of segmental expression of the cardiac-restricted ankyrin repeat protein gene by distinct regulatory pathways in murine cardiogenesis. Development (1999) 1.21
Properties of sea urchin embryo messenger RNA containing and lacking poly(A). Cell (1975) 1.21
Heterogeneous ribonucleoprotein particles in the cytoplasm of sea urchin embryos. J Mol Biol (1968) 1.19
Lacrimal gland HGF, KGF, and EGF mRNA levels increase after corneal epithelial wounding. Invest Ophthalmol Vis Sci (1999) 1.18
Expression of atrial natriuretic factor gene in heart ventricular tissue. Peptides (1987) 1.17
GATA4: a novel transcriptional regulator of cardiac hypertrophy? Circulation (1997) 1.17
Homodimer formation is rate-limiting for high affinity DNA binding by glucocorticoid receptor. Mol Endocrinol (1992) 1.17
Reversal of cardiac hypertrophy in transgenic disease models by calcineurin inhibition. J Mol Cell Cardiol (2000) 1.15
Serum response factor-GATA ternary complex required for nuclear signaling by a G-protein-coupled receptor. Mol Cell Biol (2001) 1.14
Radioimmunoassay of atrial natriuretic factor: human plasma levels. Biochem Biophys Res Commun (1985) 1.13
Complement receptor 2 mediates enhancement of human immunodeficiency virus 1 infection in Epstein-Barr virus-carrying B cells. J Exp Med (1990) 1.13
Differential expression of natriuretic peptide genes in cardiac and extracardiac tissues. Mol Endocrinol (1991) 1.11
Analysis of genetic alterations in primary nasopharyngeal carcinoma by comparative genomic hybridization. Genes Chromosomes Cancer (2001) 1.10
Structure of the rat pro-opiomelanocortin (POMC) gene. FEBS Lett (1985) 1.09
Contribution of both STAT and SRF/TCF to c-fos promoter activation by granulocyte-macrophage colony-stimulating factor. Blood (1996) 1.09
Pathogenesis of dilated cardiomyopathy: molecular, structural, and population analyses in tropomodulin-overexpressing transgenic mice. Am J Pathol (1999) 1.09
Regulation of heart development and function through combinatorial interactions of transcription factors. Ann Med (2001) 1.08
Cloning and characterization of mouse extracellular-signal-regulated protein kinase 3 as a unique gene product of 100 kDa. Biochem J (2000) 1.08
Combinatorial interactions regulating cardiac transcription. Dev Genet (1998) 1.08
Transcription factor SCL is required for c-kit expression and c-Kit function in hemopoietic cells. J Exp Med (1998) 1.08
A nuclear pathway for alpha 1-adrenergic receptor signaling in cardiac cells. EMBO J (1993) 1.07
Calcineurin enhances MAPK phosphatase-1 expression and p38 MAPK inactivation in cardiac myocytes. J Biol Chem (2001) 1.06
Dystrophin expression in myotubes formed by the fusion of normal and dystrophic myoblasts. Muscle Nerve (1991) 1.05