Purified poloxamer 188 for treatment of acute vaso-occlusive crisis of sickle cell disease: A randomized controlled trial.

PubWeight™: 2.06‹?› | Rank: Top 2%

🔗 View Article (PMID 11694150)

Published in JAMA on November 07, 2001

Authors

E P Orringer1, J F Casella, K I Ataga, M Koshy, P Adams-Graves, L Luchtman-Jones, T Wun, M Watanabe, F Shafer, A Kutlar, M Abboud, M Steinberg, B Adler, P Swerdlow, C Terregino, S Saccente, B Files, S Ballas, R Brown, S Wojtowicz-Praga, J M Grindel

Author Affiliations

1: School of Medicine, University of North Carolina at Chapel Hill, Room 125, MacNider Bldg, CB7000, Chapel Hill, NC 27599-7000, USA. epo@med.unc.edu

Articles citing this

The hydrodynamic radii of macromolecules and their effect on red blood cell aggregation. Biophys J (2004) 2.31

A multicenter randomized controlled trial of intravenous magnesium for sickle cell pain crisis in children. Blood (2015) 1.44

Nitric oxide for inhalation in the acute treatment of sickle cell pain crisis: a randomized controlled trial. JAMA (2011) 1.38

Vascular anastomosis using controlled phase transitions in poloxamer gels. Nat Med (2011) 1.24

Hydroxyurea and acute painful crises in sickle cell anemia: effects on hospital length of stay and opioid utilization during hospitalization, outpatient acute care contacts, and at home. J Pain Symptom Manage (2010) 1.09

Pluronic microemulsions as nanoreservoirs for extraction of bupivacaine from normal saline. J Am Chem Soc (2004) 1.02

Interaction between lipid monolayers and poloxamer 188: an X-ray reflectivity and diffraction study. Biophys J (2005) 0.98

IMPROVE trial: a randomized controlled trial of patient-controlled analgesia for sickle cell painful episodes: rationale, design challenges, initial experience, and recommendations for future studies. Clin Trials (2013) 0.96

Randomized phase 2 study of GMI-1070 in SCD: reduction in time to resolution of vaso-occlusive events and decreased opioid use. Blood (2015) 0.96

MP4CO, a pegylated hemoglobin saturated with carbon monoxide, is a modulator of HO-1, inflammation, and vaso-occlusion in transgenic sickle mice. Blood (2013) 0.95

Structural and functional recovery of electropermeabilized skeletal muscle in-vivo after treatment with surfactant poloxamer 188. Biochim Biophys Acta (2007) 0.94

Pharmacotherapy in sickle cell disease--state of the art and future prospects. Br J Haematol (2009) 0.92

Preparation and anesthetic properties of propofol microemulsions in rats. Anesthesiology (2006) 0.91

Intravenous magnesium for pediatric sickle cell vaso-occlusive crisis: methodological issues of a randomized controlled trial. Pediatr Blood Cancer (2014) 0.90

A pilot study of eptifibatide for treatment of acute pain episodes in sickle cell disease. Thromb Res (2013) 0.88

Beyond hydroxyurea: new and old drugs in the pipeline for sickle cell disease. Blood (2016) 0.87

Novel insights in the management of sickle cell disease in childhood. World J Clin Pediatr (2016) 0.86

Poloxamer 188 facilitates the repair of alveolus resident cells in ventilator-injured lungs. Am J Respir Crit Care Med (2011) 0.84

Genomic approaches to identifying targets for treating β hemoglobinopathies. BMC Med Genomics (2015) 0.83

Effects of poloxamer 188 on human PMN cells. Surgery (2008) 0.83

Pathophisiology of sickle cell disease and new drugs for the treatment. Mediterr J Hematol Infect Dis (2009) 0.80

Effects of amphiphilic star-shaped poly(ethylene glycol) polymers with a cholic acid core on human red blood cell aggregation. J Mech Behav Biomed Mater (2012) 0.80

The challenge of painful crisis in sickle cell disease. JAMA (2001) 0.78

Endoscopic ultrasound-guided celiac plexus neurolysis using a reverse phase polymer. World J Gastroenterol (2010) 0.78

MEK inhibitors, novel anti-adhesive molecules, reduce sickle red blood cell adhesion in vitro and in vivo, and vasoocclusion in vivo. PLoS One (2014) 0.78

Biologic complexity in sickle cell disease: implications for developing targeted therapeutics. ScientificWorldJournal (2013) 0.77

Differential effects of commercial-grade and purified poloxamer 188 on renal function. Drugs R D (2014) 0.77

Score Predicting Acute Chest Syndrome During Vaso-occlusive Crises in Adult Sickle-cell Disease Patients. EBioMedicine (2016) 0.75

Pediatric sickle cell disease: past successes and future challenges. Pediatr Res (2016) 0.75

Thromboelastographic and pharmacokinetic profiles of micro- and macro-emulsions of propofol in swine. Biopharm Drug Dispos (2010) 0.75

Resealing of electroporation of porcine epidermis using phospholipids and poloxamers. Int J Pharm (2006) 0.75

Biomarkers and recent advances in the management and therapy of sickle cell disease. F1000Res (2015) 0.75

Developing new pharmacotherapeutic approaches to treating sickle-cell disease. ISBT Sci Ser (2016) 0.75

Articles by these authors

All-atom empirical potential for molecular modeling and dynamics studies of proteins. J Phys Chem B (1998) 54.00

Urban residential environments and senior citizens' longevity in megacity areas: the importance of walkable green spaces. J Epidemiol Community Health (2002) 7.79

Prevention of a first stroke by transfusions in children with sickle cell anemia and abnormal results on transcranial Doppler ultrasonography. N Engl J Med (1998) 6.88

Prospective evaluation of cancer clinical trial accrual patterns: identifying potential barriers to enrollment. J Clin Oncol (2001) 6.83

Intestinal mucosal lesion in low-flow states. I. A morphological, hemodynamic, and metabolic reappraisal. Arch Surg (1970) 5.62

Epilepsy and exacerbation of brain injury in mice lacking the glutamate transporter GLT-1. Science (1997) 5.13

Action spectra for phytochrome A- and B-specific photoinduction of seed germination in Arabidopsis thaliana. Proc Natl Acad Sci U S A (1996) 4.48

Mental and behavioral disturbances in dementia: findings from the Cache County Study on Memory in Aging. Am J Psychiatry (2000) 4.23

Comparison of pharmacokinetics and systemic effects of inhaled fluticasone propionate in patients with asthma and healthy volunteers: a randomised crossover study. Lancet (2000) 4.22

Randomised study of cognitive effects of iron supplementation in non-anaemic iron-deficient adolescent girls. Lancet (1996) 4.20

Anastrozole is superior to tamoxifen as first-line therapy for advanced breast cancer in postmenopausal women: results of a North American multicenter randomized trial. Arimidex Study Group. J Clin Oncol (2000) 4.03

Smad4 and FAST-1 in the assembly of activin-responsive factor. Nature (1997) 3.66

Insulin-regulatable tissues express a unique insulin-sensitive glucose transport protein. Nature (1988) 3.57

Nationalism and patriotism: national identification and out-group rejection. Br J Soc Psychol (2001) 3.33

Anastrozole versus tamoxifen as first-line therapy for advanced breast cancer in 668 postmenopausal women: results of the Tamoxifen or Arimidex Randomized Group Efficacy and Tolerability study. J Clin Oncol (2000) 3.33

A comparison of conservative and aggressive transfusion regimens in the perioperative management of sickle cell disease. The Preoperative Transfusion in Sickle Cell Disease Study Group. N Engl J Med (1995) 3.24

Cloning of a bcl-2 homologue by interaction with adenovirus E1B 19K. Nature (1995) 3.22

Inactivation of the N-CAM gene in mice results in size reduction of the olfactory bulb and deficits in spatial learning. Nature (1994) 3.19

Hydroxyurea: effects on hemoglobin F production in patients with sickle cell anemia. Blood (1992) 3.09

Prevalence of urethral Chlamydia trachomatis and Neisseria gonorrhoeae among asymptomatic, sexually active adolescent boys. J Infect Dis (1987) 3.02

Trauma care regionalization: a process-outcome evaluation. J Trauma (1999) 3.02

The gene mutated in ataxia-ocular apraxia 1 encodes the new HIT/Zn-finger protein aprataxin. Nat Genet (2001) 3.01

11beta-hydroxysteroid dehydrogenase type 1 knockout mice show attenuated glucocorticoid-inducible responses and resist hyperglycemia on obesity or stress. Proc Natl Acad Sci U S A (1997) 3.00

Detection of specific anti-leptospiral immunoglobulins M and G in human serum by solid-phase enzyme-linked immunosorbent assay. J Clin Microbiol (1980) 2.99

The S receptor kinase determines self-incompatibility in Brassica stigma. Nature (2000) 2.96

A prospective assessment of mortality in chronic spinal cord injury. Spinal Cord (2005) 2.96

Clinical aspects of X-linked hypohidrotic ectodermal dysplasia. Arch Dis Child (1987) 2.95

Reaction of endotoxin and surfactants. I. Physical and biological properties of endotoxin treated with sodium deoxycholate. J Bacteriol (1966) 2.86

Evaluation of readability and accuracy of information leaflets in general practice for patients with asthma. BMJ (1998) 2.75

The London Position Statement of the World Congress of Gastroenterology on Biological Therapy for IBD with the European Crohn's and Colitis Organization: when to start, when to stop, which drug to choose, and how to predict response? Am J Gastroenterol (2010) 2.74

Drosophila CtBP: a Hairy-interacting protein required for embryonic segmentation and hairy-mediated transcriptional repression. EMBO J (1998) 2.74

Diversity revealed by a novel family of cadherins expressed in neurons at a synaptic complex. Neuron (1998) 2.73

H-2 restriction of cell-mediated immunity to an intracellular bacterium: effector T cells are specific for Listeria antigen in association with H-21 region-coded self-markers. J Exp Med (1977) 2.71

Direct ligand-receptor complex interaction controls Brassica self-incompatibility. Nature (2001) 2.69

Functional organization and nucleotide sequence of virulence Region-2 on the large virulence plasmid in Shigella flexneri 2a. Mol Microbiol (1989) 2.68

Cancer morbidity in rheumatoid arthritis. Ann Rheum Dis (1984) 2.67

Neuropsychiatric disturbance in Alzheimer's disease clusters into three groups: the Cache County study. Int J Geriatr Psychiatry (2001) 2.63

Cytochalasin D inhibits actin polymerization and induces depolymerization of actin filaments formed during platelet shape change. Nature (1981) 2.63

Impairment of suckling response, trigeminal neuronal pattern formation, and hippocampal LTD in NMDA receptor epsilon 2 subunit mutant mice. Neuron (1996) 2.62

Anastrozole is superior to tamoxifen as first-line therapy in hormone receptor positive advanced breast carcinoma. Cancer (2001) 2.58

The antibodies involved in the human immune response to leptospiral infection. J Med Microbiol (1978) 2.57

Arrest of preterm labour and prolongation of gestation with glyceryl trinitrate, a nitric oxide donor. Lancet (1994) 2.53

Temperature-regulated expression of invasion genes in Shigella flexneri is controlled through the transcriptional activation of the virB gene on the large plasmid. Mol Microbiol (1991) 2.52

Evidence for a polar ethane cloud on Titan. Science (2006) 2.50

The pollen determinant of self-incompatibility in Brassica campestris. Proc Natl Acad Sci U S A (2000) 2.50

Oxygen radical inhibition of nitric oxide-dependent vascular function in sickle cell disease. Proc Natl Acad Sci U S A (2001) 2.48

The evolution of Titan's mid-latitude clouds. Science (2005) 2.46

The effect of tetraethylammonium chloride on potassium permeability in the smooth muscle cell membrane of canine trachea. J Physiol (1981) 2.45

Hand-held thoracic sonography for detecting post-traumatic pneumothoraces: the Extended Focused Assessment with Sonography for Trauma (EFAST). J Trauma (2004) 2.44

Prefrontal and cingulate unit activity during timing behavior in the monkey. Brain Res (1979) 2.41

Human N-ras: cDNA cloning and gene structure. Nucleic Acids Res (1985) 2.41

Ampulla cardiomyopathy ('Takotusbo' cardiomyopathy)--reversible left ventricular dysfunction: with ST segment elevation. Jpn Circ J (2000) 2.39

The glycoprotein encoded by the X-linked chronic granulomatous disease locus is a component of the neutrophil cytochrome b complex. Nature (1987) 2.38

Cloning of a new murine endogenous retrovirus, MuERV-L, with strong similarity to the human HERV-L element and with a gag coding sequence closely related to the Fv1 restriction gene. J Virol (1997) 2.35

An evaluation of the Gaspak system in the culture of anaerobic bacteria. J Appl Bacteriol (1972) 2.33

Impairment of AMPA receptor function in cerebellar granule cells of ataxic mutant mouse stargazer. J Neurosci (1999) 2.27

Longitudinal study of cerebrospinal fluid levels of tau, A beta1-40, and A beta1-42(43) in Alzheimer's disease: a study in Japan. Ann Neurol (1998) 2.25

Impact of chronic transfusion on incidence of pain and acute chest syndrome during the Stroke Prevention Trial (STOP) in sickle-cell anemia. J Pediatr (2001) 2.24

Flat neoplastic lesions of the colon and rectum detected by high-resolution video endoscopy and chromoscopy. Gastrointest Endosc (1995) 2.22

Symptoms of depression and survival experience among three samples of smokers trying to quit. Psychol Addict Behav (2001) 2.20

Use of a novel approach, termed island probing, identifies the Shigella flexneri she pathogenicity island which encodes a homolog of the immunoglobulin A protease-like family of proteins. Infect Immun (1997) 2.17

Reversal of drug resistance in human tumor xenografts by 2'-deoxy-5-azacytidine-induced demethylation of the hMLH1 gene promoter. Cancer Res (2000) 2.17

Mental-physical co-morbidity and its relationship with disability: results from the World Mental Health Surveys. Psychol Med (2008) 2.15

Delay activity of orbital and lateral prefrontal neurons of the monkey varying with different rewards. Cereb Cortex (2000) 2.15

Intramuscular rocuronium in infants and children. Dose-ranging and tracheal intubating conditions. Anesthesiology (1996) 2.14

Genomic organization of the S locus: Identification and characterization of genes in SLG/SRK region of S(9) haplotype of Brassica campestris (syn. rapa). Genetics (1999) 2.12

Cause of death in rheumatoid arthritis. Br J Rheumatol (1984) 2.12

Loss of bacterial diversity during antibiotic treatment of intubated patients colonized with Pseudomonas aeruginosa. J Clin Microbiol (2007) 2.12

Laparoscopic observations of congenital anomalies of the liver. Gastrointest Endosc (1998) 2.10

Statistical analysis of the 5' untranslated region of human mRNA using "Oligo-Capped" cDNA libraries. Genomics (2000) 2.09

Insuring Latinos against the costs of illness. JAMA (1993) 2.09

Purification and initial characterization of a protein from skeletal muscle that caps the barbed ends of actin filaments. J Biol Chem (1986) 2.08

An autopsy case of troglitazone-induced fulminant hepatitis. Diabetes Care (1998) 2.08

Transplantation of in vitro-expanded fetal neural progenitor cells results in neurogenesis and functional recovery after spinal cord contusion injury in adult rats. J Neurosci Res (2002) 2.06

Adiponectin suppresses colorectal carcinogenesis under the high-fat diet condition. Gut (2008) 2.05

Phylogenetic relationships between toxic and non-toxic strains of the genus Microcystis based on 16S to 23S internal transcribed spacer sequence. FEMS Microbiol Lett (1999) 2.04

A pharmacodynamic explanation for the rapid onset/offset of rapacuronium bromide. Anesthesiology (1999) 2.03

Cisplatin and adriamycin resistance are associated with MutLalpha and mismatch repair deficiency in an ovarian tumor cell line. J Biol Chem (1996) 2.01

Cap Z(36/32), a barbed end actin-capping protein, is a component of the Z-line of skeletal muscle. J Cell Biol (1987) 2.01

Second cancers following radiation treatment for cervical cancer. An international collaboration among cancer registries. J Natl Cancer Inst (1985) 2.00

New cosmid vectors developed for eukaryotic DNA cloning. Gene (1984) 1.97

Acute infectious epiglottitis in adults. Ann Intern Med (1969) 1.97

Characterization of a broadly expressed human leucocyte surface antigen MEM-43 anchored in membrane through phosphatidylinositol. Mol Immunol (1989) 1.94

Training in international animal health. Vet Rec (2001) 1.93

EXPERIENCES WITH SODIUM AMYTAL AS A GENERAL ANAESTHETIC. Ann Surg (1930) 1.93

Recruitment in the Cooperative Study of Sickle Cell Disease (CSSCD). Control Clin Trials (1987) 1.93

Genetic organization of Pasteurella multocida cap Loci and development of a multiplex capsular PCR typing system. J Clin Microbiol (2001) 1.93

A death-domain-containing receptor that mediates apoptosis. Nature (1996) 1.92

Interstitial lung disease in recent onset rheumatoid arthritis. Am J Respir Crit Care Med (1997) 1.92

Ataxia with oculomotor apraxia type 2: clinical, biological and genotype/phenotype correlation study of a cohort of 90 patients. Brain (2009) 1.91

Motor discoordination and increased susceptibility to cerebellar injury in GLAST mutant mice. Eur J Neurosci (1998) 1.90

An evaluated programme of rheumatology training for general practitioners. Br J Rheumatol (1986) 1.88

Needs-based planning: the case of Manitoba. CMAJ (1997) 1.87

Sickle cell disease as a cause of osteonecrosis of the femoral head. N Engl J Med (1991) 1.86

Poly(ADP-ribose) polymerase gene disruption conferred mice resistant to streptozotocin-induced diabetes. Proc Natl Acad Sci U S A (1999) 1.85

Apo E structure determines VLDL clearance and atherosclerosis risk in mice. J Clin Invest (1999) 1.85