Published in EMBO J on April 01, 1998
Tcf3 and Lef1 regulate lineage differentiation of multipotent stem cells in skin. Genes Dev (2001) 4.62
Cloning and characterization of mCtBP2, a co-repressor that associates with basic Krüppel-like factor and other mammalian transcriptional regulators. EMBO J (1998) 3.06
Overlapping and unique roles for C-terminal binding protein 1 (CtBP1) and CtBP2 during mouse development. Mol Cell Biol (2002) 2.78
ZEB represses transcription through interaction with the corepressor CtBP. Proc Natl Acad Sci U S A (1999) 2.64
Delta-Notch--and then? Protein interactions and proposed modes of repression by Hes and Hey bHLH factors. Nucleic Acids Res (2007) 2.51
dCtBP mediates transcriptional repression by Knirps, Krüppel and Snail in the Drosophila embryo. EMBO J (1998) 2.22
Transcriptional cofactors of the FOG family interact with GATA proteins by means of multiple zinc fingers. EMBO J (1999) 2.21
Keeping a good pathway down: transcriptional repression of Notch pathway target genes by CSL proteins. EMBO Rep (2002) 2.21
Miranda mediates asymmetric protein and RNA localization in the developing nervous system. Genes Dev (1998) 2.13
C-terminal-binding protein directly activates and represses Wnt transcriptional targets in Drosophila. EMBO J (2006) 2.01
C-Terminal binding protein is a transcriptional repressor that interacts with a specific class of vertebrate Polycomb proteins. Mol Cell Biol (1999) 1.97
Transcription factor YY1 functions as a PcG protein in vivo. EMBO J (2003) 1.95
Default repression and Notch signaling: Hairless acts as an adaptor to recruit the corepressors Groucho and dCtBP to Suppressor of Hairless. Genes Dev (2002) 1.87
The family feud: turning off Sp1 by Sp1-like KLF proteins. Biochem J (2005) 1.83
A mechanism for Rb/p130-mediated transcription repression involving recruitment of the CtBP corepressor. Proc Natl Acad Sci U S A (1999) 1.80
Net, a negative Ras-switchable TCF, contains a second inhibition domain, the CID, that mediates repression through interactions with CtBP and de-acetylation. EMBO J (1999) 1.76
Differential expression and function of members of the zfh-1 family of zinc finger/homeodomain repressors. Proc Natl Acad Sci U S A (2000) 1.73
Groucho and dCtBP mediate separate pathways of transcriptional repression in the Drosophila embryo. Proc Natl Acad Sci U S A (1999) 1.72
Human Slug is a repressor that localizes to sites of active transcription. Mol Cell Biol (2000) 1.63
Hairy transcriptional repression targets and cofactor recruitment in Drosophila. PLoS Biol (2004) 1.63
Acetylation of adenovirus E1A regulates binding of the transcriptional corepressor CtBP. Proc Natl Acad Sci U S A (2000) 1.58
Identification of CtBP1 and CtBP2 as corepressors of zinc finger-homeodomain factor deltaEF1. Mol Cell Biol (1999) 1.57
Hairless-mediated repression of notch target genes requires the combined activity of Groucho and CtBP corepressors. Mol Cell Biol (2005) 1.55
A SIRT1-LSD1 corepressor complex regulates Notch target gene expression and development. Mol Cell (2011) 1.55
The Rpd3 histone deacetylase is required for segmentation of the Drosophila embryo. Proc Natl Acad Sci U S A (1999) 1.55
YY1 DNA binding and PcG recruitment requires CtBP. Genes Dev (2004) 1.52
HMG box transcription factor TCF-4's interaction with CtBP1 controls the expression of the Wnt target Axin2/Conductin in human embryonic kidney cells. Nucleic Acids Res (2003) 1.49
CtIP activates its own and cyclin D1 promoters via the E2F/RB pathway during G1/S progression. Mol Cell Biol (2006) 1.48
The human candidate tumor suppressor gene HIC1 recruits CtBP through a degenerate GLDLSKK motif. Mol Cell Biol (2002) 1.34
Abundant expression of Dec1/stra13/sharp2 in colon carcinoma: its antagonizing role in serum deprivation-induced apoptosis and selective inhibition of procaspase activation. Biochem J (2002) 1.29
Physical and functional interactions between the corepressor CtBP and the Epstein-Barr virus nuclear antigen EBNA3C. J Virol (2001) 1.25
HES-1 repression of differentiation and proliferation in PC12 cells: role for the helix 3-helix 4 domain in transcription repression. Mol Cell Biol (2000) 1.21
Brinker is a sequence-specific transcriptional repressor in the Drosophila embryo. Genes Dev (2001) 1.21
Bayesian network analysis of targeting interactions in chromatin. Genome Res (2009) 1.17
A Myc-Groucho complex integrates EGF and Notch signaling to regulate neural development. Proc Natl Acad Sci U S A (2007) 1.16
Brinker requires two corepressors for maximal and versatile repression in Dpp signalling. EMBO J (2001) 1.14
The N-terminal BTB/POZ domain and C-terminal sequences are essential for Tramtrack69 to specify cell fate in the developing Drosophila eye. Genetics (2000) 1.14
CtBPs promote cell survival through the maintenance of mitotic fidelity. Mol Cell Biol (2009) 1.12
The transcriptional repressor dMnt is a regulator of growth in Drosophila melanogaster. Mol Cell Biol (2005) 1.11
dCtBP-dependent and -independent repression activities of the Drosophila Knirps protein. Mol Cell Biol (2000) 1.10
Spreading of a corepressor linked to action of long-range repressor hairy. Mol Cell Biol (2008) 1.07
Degringolade, a SUMO-targeted ubiquitin ligase, inhibits Hairy/Groucho-mediated repression. EMBO J (2011) 1.05
SOX6 binds CtBP2 to repress transcription from the Fgf-3 promoter. Nucleic Acids Res (2001) 1.05
Long- and short-range transcriptional repressors induce distinct chromatin states on repressed genes. Curr Biol (2011) 1.04
Expression of CtBP family protein isoforms in breast cancer and their role in chemoresistance. Biol Cell (2010) 1.03
Interaction of the E1A oncoprotein with Yak1p, a novel regulator of yeast pseudohyphal differentiation, and related mammalian kinases. Mol Biol Cell (2001) 1.03
Local action of long-range repressors in the Drosophila embryo. EMBO J (2001) 1.03
The Drosophila homologue of the 64 kDa subunit of cleavage stimulation factor interacts with the 77 kDa subunit encoded by the suppressor of forked gene. Nucleic Acids Res (2000) 1.02
Distinct role of Kruppel-like factor 11 in the regulation of prostaglandin E2 biosynthesis. J Biol Chem (2010) 1.02
The oligomeric state of CtBP determines its role as a transcriptional co-activator and co-repressor of Wingless targets. EMBO J (2011) 1.02
The tailless nuclear receptor acts as a dedicated repressor in the early Drosophila embryo. Mol Cell Biol (2006) 1.02
A novel GATA factor transcriptionally represses yolk protein precursor genes in the mosquito Aedes aegypti via interaction with the CtBP corepressor. Mol Cell Biol (2001) 0.99
Functional similarity of Knirps CtBP-dependent and CtBP-independent transcriptional repressor activities. Nucleic Acids Res (2003) 0.99
Direct competition between Brinker and Drosophila Mad in Dpp target gene transcription. EMBO Rep (2001) 0.95
Teashirt is required for transcriptional repression mediated by high Wingless levels. EMBO J (2001) 0.94
CtBP contributes quantitatively to Knirps repression activity in an NAD binding-dependent manner. Mol Cell Biol (2004) 0.93
Capicua integrates input from two maternal systems in Drosophila terminal patterning. EMBO J (2004) 0.93
A systems view of Drosophila segmentation. Genome Biol (2008) 0.91
The Drosophila STUbL protein Degringolade limits HES functions during embryogenesis. Development (2011) 0.90
CtBP-independent repression in the Drosophila embryo. Mol Cell Biol (2003) 0.89
Groucho corepressor functions as a cofactor for the Knirps short-range transcriptional repressor. Proc Natl Acad Sci U S A (2009) 0.88
CoREST acts as a positive regulator of Notch signaling in the follicle cells of Drosophila melanogaster. J Cell Sci (2012) 0.87
Maternal Groucho and bHLH repressors amplify the dose-sensitive X chromosome signal in Drosophila sex determination. Dev Biol (2008) 0.87
The transcriptional repressor Brinker antagonizes Wingless signaling. Genes Dev (2002) 0.87
Structurally related Arabidopsis ANGUSTIFOLIA is functionally distinct from the transcriptional corepressor CtBP. Dev Genes Evol (2007) 0.87
Hepatoma-derived growth factor represses SET and MYND domain containing 1 gene expression through interaction with C-terminal binding protein. J Mol Biol (2009) 0.86
Differential spatial expression and subcellular localization of CtBP family members in rodent brain. PLoS One (2012) 0.86
Identification and characterization of ToRC, a novel ISWI-containing ATP-dependent chromatin assembly complex. Genes Dev (2012) 0.84
C-Terminal Binding Protein: A Molecular Link between Metabolic Imbalance and Epigenetic Regulation in Breast Cancer. Int J Cell Biol (2013) 0.84
STUbLs in chromatin and genome stability. Biopolymers (2013) 0.84
Hairy and Groucho mediate the action of juvenile hormone receptor Methoprene-tolerant in gene repression. Proc Natl Acad Sci U S A (2016) 0.84
Developmental expression and phylogenetic conservation of alternatively spliced forms of the C-terminal binding protein corepressor. Dev Genes Evol (2006) 0.83
Chick Hairy1 protein interacts with Sap18, a component of the Sin3/HDAC transcriptional repressor complex. BMC Dev Biol (2007) 0.83
CtBP and associated LSD1 are required for transcriptional activation by NeuroD1 in gastrointestinal endocrine cells. Mol Cell Biol (2014) 0.82
Conserved catalytic and C-terminal regulatory domains of the C-terminal binding protein corepressor fine-tune the transcriptional response in development. Mol Cell Biol (2010) 0.81
Molecular mechanisms of EGF signaling-dependent regulation of pipe, a gene crucial for dorsoventral axis formation in Drosophila. Dev Genes Evol (2011) 0.81
CtBP levels control intergenic transcripts, PHO/YY1 DNA binding, and PcG recruitment to DNA. J Cell Biochem (2010) 0.81
A recurrent de novo CTBP1 mutation is associated with developmental delay, hypotonia, ataxia, and tooth enamel defects. Neurogenetics (2016) 0.80
C-terminal binding protein (CtBP) activates the expression of E-box clock genes with CLOCK/CYCLE in Drosophila. PLoS One (2013) 0.80
SpGataE, a Strongylocentrotus purpuratus ortholog of mammalian Gata4/5/6: protein expression, interaction with putative target gene spec2a, and identification of friend of Gata factor SpFog1. Dev Genes Evol (2007) 0.79
Genetic interactions among scribbler, Atrophin and groucho in Drosophila uncover links in transcriptional repression. Genetics (2006) 0.78
Drosophila CtBP regulates proliferation and differentiation of eye precursors and complexes with Eyeless, Dachshund, Dan, and Danr during eye and antennal development. Dev Dyn (2010) 0.77
Genome-wide errant targeting by Hairy. Elife (2015) 0.76
Screening and Analysis of Janelia FlyLight Project Enhancer-Gal4 Strains Identifies Multiple Gene Enhancers Active during Hematopoiesis in Normal and Wasp-Challenged Drosophila Larvae. G3 (Bethesda) (2016) 0.75
Oligomeric form of CtBP coactivates NeuroD1-mediated transcription. FEBS Lett (2016) 0.75
Brinker possesses multiple mechanisms for repression because its primary co-repressor, Groucho, may be unavailable in some cell types. Development (2013) 0.75
CtBP- an emerging oncogene and novel small molecule drug target: advances in the understanding of its oncogenic action and identification of therapeutic inhibitors. Cancer Biol Ther (2017) 0.75
A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins. Cell (1989) 21.54
Mammalian Ras interacts directly with the serine/threonine kinase Raf. Cell (1993) 16.91
A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback. Chromosoma (1989) 16.41
Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence. Cell (1989) 14.24
Chromosomal walking and jumping to isolate DNA from the Ace and rosy loci and the bithorax complex in Drosophila melanogaster. J Mol Biol (1983) 9.78
Insertional mutagenesis of the Drosophila genome with single P elements. Science (1988) 8.81
Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression. Cell (1997) 7.64
The molecular genetics of embryonic pattern formation in Drosophila. Nature (1988) 6.20
Gene disruptions using P transposable elements: an integral component of the Drosophila genome project. Proc Natl Acad Sci U S A (1995) 5.76
Identification of a new family of tissue-specific basic helix-loop-helix proteins with a two-hybrid system. Mol Cell Biol (1995) 5.71
Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteins. Cell (1994) 4.95
Use of a yeast site-specific recombinase to produce female germline chimeras in Drosophila. Genetics (1992) 4.18
Two mammalian helix-loop-helix factors structurally related to Drosophila hairy and Enhancer of split. Genes Dev (1992) 3.85
Site-specific recombination between homologous chromosomes in Drosophila. Science (1991) 3.70
The dorsal morphogen gradient regulates the mesoderm determinant twist in early Drosophila embryos. Genes Dev (1991) 3.45
The dorsal gradient morphogen regulates stripes of rhomboid expression in the presumptive neuroectoderm of the Drosophila embryo. Genes Dev (1992) 3.38
Molecular cloning and characterization of a cellular phosphoprotein that interacts with a conserved C-terminal domain of adenovirus E1A involved in negative modulation of oncogenic transformation. Proc Natl Acad Sci U S A (1995) 3.28
Autosomal P[ovoD1] dominant female-sterile insertions in Drosophila and their use in generating germ-line chimeras. Development (1993) 3.19
Monoclonal antibodies against the Drosophila nervous system. Proc Natl Acad Sci U S A (1982) 3.06
The WRPW motif of the hairy-related basic helix-loop-helix repressor proteins acts as a 4-amino-acid transcription repression and protein-protein interaction domain. Mol Cell Biol (1996) 3.06
DNA tumor virus transforming proteins and the cell cycle. Curr Opin Genet Dev (1993) 2.88
Closely related transcripts encoded by the neurogenic gene complex enhancer of split of Drosophila melanogaster. EMBO J (1989) 2.54
P-lacW insertional mutagenesis on the second chromosome of Drosophila melanogaster: isolation of lethals with different overgrowth phenotypes. Genetics (1993) 2.50
Characterization and developmental expression of a Drosophila ras oncogene. Mol Cell Biol (1985) 2.45
The Drosophila hairy protein acts in both segmentation and bristle patterning and shows homology to N-myc. EMBO J (1989) 2.18
Transcriptional repression in eukaryotes. Annu Rev Cell Biol (1993) 2.17
Cross-regulatory interactions among pair-rule genes in Drosophila. Science (1986) 1.98
Transcriptional repression in development. Curr Opin Cell Biol (1996) 1.96
Zygotically active genes that affect the spatial expression of the fushi tarazu segmentation gene during early Drosophila embryogenesis. Cell (1986) 1.96
Regulatory interactions between the segmentation genes fushi tarazu, hairy, and engrailed in the Drosophila blastoderm. Cell (1986) 1.95
Hairy function as a DNA-binding helix-loop-helix repressor of Drosophila sensory organ formation. Genes Dev (1994) 1.95
Gene-dose titration analysis in the search of trans-regulatory genes in Drosophila. EMBO J (1982) 1.93
Mad3 and Mad4: novel Max-interacting transcriptional repressors that suppress c-myc dependent transformation and are expressed during neural and epidermal differentiation. EMBO J (1995) 1.93
Seven genes of the Enhancer of split complex of Drosophila melanogaster encode helix-loop-helix proteins. Genetics (1992) 1.87
Negative regulation of proneural gene activity: hairy is a direct transcriptional repressor of achaete. Genes Dev (1994) 1.85
Specificity for the hairy/enhancer of split basic helix-loop-helix (bHLH) proteins maps outside the bHLH domain and suggests two separable modes of transcriptional repression. Mol Cell Biol (1995) 1.77
Zygotic lethal mutations with maternal effect phenotypes in Drosophila melanogaster. II. Loci on the second and third chromosomes identified by P-element-induced mutations. Genetics (1996) 1.76
The Enhancer of split [E(spl)] locus of Drosophila encodes seven independent helix-loop-helix proteins. Proc Natl Acad Sci U S A (1992) 1.76
Functional relationships between Notch, Su(H) and the bHLH genes of the E(spl) complex: the E(spl) genes mediate only a subset of Notch activities during imaginal development. Development (1996) 1.75
deadpan, an essential pan-neural gene in Drosophila, encodes a helix-loop-helix protein similar to the hairy gene product. Genes Dev (1992) 1.75
hairy mediates dominant repression in the Drosophila embryo. EMBO J (1997) 1.74
Cytogenetic analysis of the chromosomal region immediately adjacent to the rosy locus in Drosophila melanogaster. Genetics (1980) 1.66
X:A ratio, the primary sex-determining signal in Drosophila, is transduced by helix-loop-helix proteins. Cell (1990) 1.65
Genetic activity along 315 kb of the Drosophila chromosome. EMBO J (1984) 1.63
Chromatin-mediated transcriptional repression in yeast. Curr Opin Genet Dev (1995) 1.63
Molecular mapping of genetic and chromomeric units in Drosophila melanogaster. J Mol Biol (1983) 1.58
Groucho: making its Marx as a transcriptional co-repressor. Trends Genet (1998) 1.58
bHLH proteins encoded by the Enhancer of split complex of Drosophila negatively interfere with transcriptional activation mediated by proneural genes. Mol Gen Genet (1994) 1.49
Enhancer of splitD, a dominant mutation of Drosophila, and its use in the study of functional domains of a helix-loop-helix protein. Proc Natl Acad Sci U S A (1992) 1.48
Point mutations in the Drosophila hairy gene demonstrate in vivo requirements for basic, helix-loop-helix, and WRPW domains. Mol Cell Biol (1992) 1.35
Pattern abnormalities induced by ectopic expression of the Drosophila gene hairy are associated with repression of ftz transcription. Cell (1987) 1.33
The CtBP binding domain in the adenovirus E1A protein controls CR1-dependent transactivation. Nucleic Acids Res (1996) 1.33
Genetic Analysis of the Hairy Locus in DROSOPHILA MELANOGASTER. Genetics (1985) 1.31
Hairy and emc negatively regulate morphogenetic furrow progression in the Drosophila eye. Cell (1995) 1.22
Molecular characterization of HES-2, a mammalian helix-loop-helix factor structurally related to Drosophila hairy and Enhancer of split. Eur J Biochem (1993) 1.21
A network of interacting transcriptional regulators involved in Drosophila neural fate specification revealed by the yeast two-hybrid system. Proc Natl Acad Sci U S A (1997) 1.19
A rat gene with sequence homology to the Drosophila gene hairy is rapidly induced by growth factors known to influence neuronal differentiation. Mol Cell Biol (1993) 1.18
Spatial control of hairy protein expression during embryogenesis. Development (1989) 1.13
Molecular Genetics of the ROSY-ACE Region of DROSOPHILA MELANOGASTER. Genetics (1986) 1.13
In vivo interactions of the Drosophila Hairy and Runt transcriptional repressors with target promoters. EMBO J (1996) 1.12
wimp, a dominant maternal-effect mutation, reduces transcription of a specific subset of segmentation genes in Drosophila. Genes Dev (1991) 1.10
Functional dissection of the Drosophila enhancer of split protein, a suppressor of neurogenesis. Proc Natl Acad Sci U S A (1997) 1.10
Tumour suppressive properties of the adenovirus 5 E1A oncogene. Oncogene (1996) 1.04
Transcriptional regulation of the Sex-lethal gene by helix-loop-helix proteins. Nucleic Acids Res (1995) 1.04
Transcriptional repression in the Drosophila embryo. Philos Trans R Soc Lond B Biol Sci (1995) 1.02
Genomic cloning and chromosomal localization of HRY, the human homolog to the Drosophila segmentation gene, hairy. Genomics (1994) 1.00
hairy gene function in the Drosophila eye: normal expression is dispensable but ectopic expression alters cell fates. Development (1991) 0.92
Adenovirus E1a as a tumor-suppressor gene. Oncogene (1992) 0.89
Drosophila development. Delimiting patterns by repression. Curr Biol (1997) 0.85
All-atom empirical potential for molecular modeling and dynamics studies of proteins. J Phys Chem B (1998) 54.00
Urban residential environments and senior citizens' longevity in megacity areas: the importance of walkable green spaces. J Epidemiol Community Health (2002) 7.79
Epilepsy and exacerbation of brain injury in mice lacking the glutamate transporter GLT-1. Science (1997) 5.13
Action spectra for phytochrome A- and B-specific photoinduction of seed germination in Arabidopsis thaliana. Proc Natl Acad Sci U S A (1996) 4.48
Smad4 and FAST-1 in the assembly of activin-responsive factor. Nature (1997) 3.66
The Drosophila melanogaster gypsy transposable element encodes putative gene products homologous to retroviral proteins. Mol Cell Biol (1986) 3.65
Interactions among the gypsy transposable element and the yellow and the suppressor of hairy-wing loci in Drosophila melanogaster. Mol Cell Biol (1986) 3.30
Forked, gypsys, and suppressors in Drosophila. Cell (1985) 3.13
The gene mutated in ataxia-ocular apraxia 1 encodes the new HIT/Zn-finger protein aprataxin. Nat Genet (2001) 3.01
The S receptor kinase determines self-incompatibility in Brassica stigma. Nature (2000) 2.96
The London Position Statement of the World Congress of Gastroenterology on Biological Therapy for IBD with the European Crohn's and Colitis Organization: when to start, when to stop, which drug to choose, and how to predict response? Am J Gastroenterol (2010) 2.74
Diversity revealed by a novel family of cadherins expressed in neurons at a synaptic complex. Neuron (1998) 2.73
Direct ligand-receptor complex interaction controls Brassica self-incompatibility. Nature (2001) 2.69
Impairment of suckling response, trigeminal neuronal pattern formation, and hippocampal LTD in NMDA receptor epsilon 2 subunit mutant mice. Neuron (1996) 2.62
The pollen determinant of self-incompatibility in Brassica campestris. Proc Natl Acad Sci U S A (2000) 2.50
The effect of tetraethylammonium chloride on potassium permeability in the smooth muscle cell membrane of canine trachea. J Physiol (1981) 2.45
Prefrontal and cingulate unit activity during timing behavior in the monkey. Brain Res (1979) 2.41
Ampulla cardiomyopathy ('Takotusbo' cardiomyopathy)--reversible left ventricular dysfunction: with ST segment elevation. Jpn Circ J (2000) 2.39
Impairment of AMPA receptor function in cerebellar granule cells of ataxic mutant mouse stargazer. J Neurosci (1999) 2.27
Longitudinal study of cerebrospinal fluid levels of tau, A beta1-40, and A beta1-42(43) in Alzheimer's disease: a study in Japan. Ann Neurol (1998) 2.25
Flat neoplastic lesions of the colon and rectum detected by high-resolution video endoscopy and chromoscopy. Gastrointest Endosc (1995) 2.22
Mental-physical co-morbidity and its relationship with disability: results from the World Mental Health Surveys. Psychol Med (2008) 2.15
Delay activity of orbital and lateral prefrontal neurons of the monkey varying with different rewards. Cereb Cortex (2000) 2.15
Genomic organization of the S locus: Identification and characterization of genes in SLG/SRK region of S(9) haplotype of Brassica campestris (syn. rapa). Genetics (1999) 2.12
Laparoscopic observations of congenital anomalies of the liver. Gastrointest Endosc (1998) 2.10
Statistical analysis of the 5' untranslated region of human mRNA using "Oligo-Capped" cDNA libraries. Genomics (2000) 2.09
An autopsy case of troglitazone-induced fulminant hepatitis. Diabetes Care (1998) 2.08
Purified poloxamer 188 for treatment of acute vaso-occlusive crisis of sickle cell disease: A randomized controlled trial. JAMA (2001) 2.06
Transplantation of in vitro-expanded fetal neural progenitor cells results in neurogenesis and functional recovery after spinal cord contusion injury in adult rats. J Neurosci Res (2002) 2.06
Adiponectin suppresses colorectal carcinogenesis under the high-fat diet condition. Gut (2008) 2.05
Phylogenetic relationships between toxic and non-toxic strains of the genus Microcystis based on 16S to 23S internal transcribed spacer sequence. FEMS Microbiol Lett (1999) 2.04
Ataxia with oculomotor apraxia type 2: clinical, biological and genotype/phenotype correlation study of a cohort of 90 patients. Brain (2009) 1.91
Motor discoordination and increased susceptibility to cerebellar injury in GLAST mutant mice. Eur J Neurosci (1998) 1.90
Needs-based planning: the case of Manitoba. CMAJ (1997) 1.87
Myc and Max homologs in Drosophila. Science (1996) 1.85
Poly(ADP-ribose) polymerase gene disruption conferred mice resistant to streptozotocin-induced diabetes. Proc Natl Acad Sci U S A (1999) 1.85
Apo E structure determines VLDL clearance and atherosclerosis risk in mice. J Clin Invest (1999) 1.85
Convergence of transforming growth factor-beta and vitamin D signaling pathways on SMAD transcriptional coactivators. Science (1999) 1.85
Glutamate transporter GLAST is expressed in the radial glia-astrocyte lineage of developing mouse spinal cord. J Neurosci (1997) 1.84
Left-right asymmetric expression of lefty2 and nodal is induced by a signaling pathway that includes the transcription factor FAST2. Mol Cell (2000) 1.78
Specificity for the hairy/enhancer of split basic helix-loop-helix (bHLH) proteins maps outside the bHLH domain and suggests two separable modes of transcriptional repression. Mol Cell Biol (1995) 1.77
Two-step regulation of left-right asymmetric expression of Pitx2: initiation by nodal signaling and maintenance by Nkx2. Mol Cell (2001) 1.77
Photoisomerization of retinal at 13-ene is important for phototaxis of Chlamydomonas reinhardtii: simultaneous measurements of phototactic and photophobic responses. Biochem Biophys Res Commun (1991) 1.77
Per anum intersphincteric rectal dissection with direct coloanal anastomosis for lower rectal cancer: the ultimate sphincter-preserving operation. Dis Colon Rectum (1997) 1.76
Characterization of a renal tubular epithelial cell line which secretes the autologous target antigen of autoimmune experimental interstitial nephritis. J Cell Biol (1988) 1.75
Ultrahigh-speed optical coherence tomography imaging and visualization of the embryonic avian heart using a buffered Fourier Domain Mode Locked laser. Opt Express (2007) 1.75
Predictive factors for metachronous recurrence of early gastric cancer after endoscopic treatment. J Clin Gastroenterol (1999) 1.73
Expression and localization of Drosophila melanogaster hsp70 cognate proteins. Mol Cell Biol (1986) 1.72
Effects of cyclopiazonic acid, a novel Ca(2+)-ATPase inhibitor, on contractile responses in skinned ileal smooth muscle. Br J Pharmacol (1992) 1.71
Irinotecan (CPT-11) and characteristic mucosal changes in the mouse ileum and cecum. J Natl Cancer Inst (1995) 1.71
4D embryonic cardiography using gated optical coherence tomography. Opt Express (2006) 1.71
Mutations in the Rho1 small GTPase disrupt morphogenesis and segmentation during early Drosophila development. Development (1999) 1.69
Molecular cloning and characterization of complementary DNA encoding for ferredoxin-dependent glutamate synthase in maize leaf. J Biol Chem (1991) 1.69
Restoration of prehension with the double free muscle technique following complete avulsion of the brachial plexus. Indications and long-term results. J Bone Joint Surg Am (2000) 1.68
A truncated isoform of the PP2A B56 subunit promotes cell motility through paxillin phosphorylation. EMBO J (2000) 1.67
Glial cells express N-CAM/D2-CAM-like polypeptides in vitro. Nature (1985) 1.66
Induction of the acyl-coenzyme A synthetase gene by fibrates and fatty acids is mediated by a peroxisome proliferator response element in the C promoter. J Biol Chem (1995) 1.66
CREB-H: a novel mammalian transcription factor belonging to the CREB/ATF family and functioning via the box-B element with a liver-specific expression. Nucleic Acids Res (2001) 1.62
Purification and some properties of staphylococcal alpha-toxin. Jpn J Exp Med (1974) 1.62
Impaired motor coordination and persistent multiple climbing fiber innervation of cerebellar Purkinje cells in mice lacking Galphaq. Proc Natl Acad Sci U S A (1997) 1.62
Randomized controlled trial of laparoscopic versus open colectomy for advanced colorectal cancer. Surg Endosc (2003) 1.61
Optical pacing of the embryonic heart. Nat Photonics (2010) 1.61
Blockade of Ca-activated K conductance by apamin in rat sympathetic neurones. Br J Pharmacol (1986) 1.61
Functional expression of costimulatory molecule CD86 on epithelial cells in the inflamed colonic mucosa. Gastroenterology (1999) 1.61
Intraspinal cyst communicating with the intervertebral disc in the lumbar spine: discal cyst. Spine (Phila Pa 1976) (2001) 1.60
Structural components of Sendai virus. Serological and physicochemical characterization of hemagglutinin subunit associated with neuraminidase activity. Virology (1973) 1.60
Dissecting the protein kinase C/MAP kinase signalling pathway of Saccharomyces cerevisiae. Cell Mol Biol Res (1994) 1.59
A call for action from the National Forum on Health. CMAJ (1997) 1.59
Gadolinium-enhanced three-dimensional magnetization-prepared rapid gradient-echo (3D MP-RAGE) imaging is superior to spin-echo imaging in delineating brain metastases. Acta Radiol (2008) 1.58
Mutational spectrum of the CHAC gene in patients with chorea-acanthocytosis. Eur J Hum Genet (2002) 1.56
Ca2+ images and K+ current during depolarization in smooth muscle cells of the guinea-pig vas deferens and urinary bladder. J Physiol (1998) 1.54
Effectiveness of interferon-alpha therapy in chronic hepatitis C is associated with the amount of interferon-alpha receptor mRNA in the liver. J Hepatol (1997) 1.54
An assessment of local curability of endoscopic surgery in early gastric cancer without satisfaction of current therapeutic indications. Endoscopy (1998) 1.53
Modeling, synthesis and biological activity of novel antifungal agents (1). Bioorg Med Chem Lett (1998) 1.52
Malignant transformation of pleomorphic xanthoastrocytoma. Acta Neurochir (Wien) (2005) 1.52
Associations of various gene polymorphisms with toxicity in colorectal cancer patients receiving oral uracil and tegafur plus leucovorin: a prospective study. Ann Oncol (2010) 1.52
Signal transduction by cAMP-dependent protein kinase A in Drosophila limb patterning. Nature (1995) 1.51
Expression of the vesicular glutamate transporters-1 and -2 in adult mouse dorsal root ganglia and spinal cord and their regulation by nerve injury. Neuroscience (2007) 1.51
Constructing a local district telepathology network in Japan. Diagnosis of intraoperative frozen sections via telepathology over an integrated service digital network and the National Television Standard Committee System. Anal Quant Cytol Histol (1999) 1.50
CSF hypocretin levels in Guillain-Barré syndrome and other inflammatory neuropathies. Neurology (2003) 1.50
Specific alteration of NCAM-mediated cell adhesion by an endoneuraminidase. J Cell Biol (1985) 1.49
Developmental expression of Drosophila melanogaster retrovirus-like transposable elements. EMBO J (1987) 1.49
Cardiovascular basic helix loop helix factor 1, a novel transcriptional repressor expressed preferentially in the developing and adult cardiovascular system. J Biol Chem (2000) 1.49
Characteristic sequences in the upstream region of the human tyrosinase gene. Biochim Biophys Acta (1989) 1.47
A second p53-related protein, p73L, with high homology to p73. Biochem Biophys Res Commun (1998) 1.47
Circulating autoantibodies against purified colonic mucin in ulcerative colitis. J Gastroenterol (2000) 1.46
The role of the sentinel lymph node in gastrointestinal cancer. Surg Clin North Am (2000) 1.46
Mechanism of abnormal postexercise systolic blood pressure response and its diagnostic value in patients with coronary artery disease. Am Heart J (1990) 1.45
Association of the human lymphocyte-DR2 antigen with Japanese ulcerative colitis. Gastroenterology (1982) 1.45
Developing a "clinical presentation" curriculum at the University of Calgary. Acad Med (1995) 1.44
Acute myeloblastic leukemia (ANLL-M2) with t(8;21)(q22;q22) variant expressing lymphoid but not myeloid surface antigens with a high number of G-CSF receptors. Leuk Res (1993) 1.44
A novel "patient-like" treatment model of human pancreatic cancer constructed using orthotopic transplantation of histologically intact human tumor tissue in nude mice. Cancer Res (1993) 1.44
Persistent multiple climbing fiber innervation of cerebellar Purkinje cells in mice lacking mGluR1. Neuron (1997) 1.44
Small, flat colorectal neoplasias in long-standing ulcerative colitis detected by high-resolution electronic video endoscopy. Gastrointest Endosc (1996) 1.43
Contrasting action of IL-12 and IL-18 in the development of dextran sodium sulphate colitis in mice. Scand J Gastroenterol (2003) 1.41
Radiation-induced long-lived radicals which cause mutation and transformation. Mutat Res (1998) 1.41
Impaired parallel fiber-->Purkinje cell synapse stabilization during cerebellar development of mutant mice lacking the glutamate receptor delta2 subunit. J Neurosci (1997) 1.41
BTEB2, a Krüppel-like transcription factor, regulates expression of the SMemb/Nonmuscle myosin heavy chain B (SMemb/NMHC-B) gene. Circ Res (1999) 1.40
Cyclopiazonic acid, an inhibitor of the sarcoplasmic reticulum Ca(2+)-pump, reduces Ca(2+)-dependent K+ currents in guinea-pig smooth muscle cells. Br J Pharmacol (1992) 1.40