Published in Genomics on December 01, 2001
Regulation of innate antiviral defenses through a shared repressor domain in RIG-I and LGP2. Proc Natl Acad Sci U S A (2006) 5.70
Inactivation of Stat5 in mouse mammary epithelium during pregnancy reveals distinct functions in cell proliferation, survival, and differentiation. Mol Cell Biol (2004) 4.45
Function and regulation of retinoic acid-inducible gene-I. Crit Rev Immunol (2010) 1.15
Activation of RIG-I-like receptor signal transduction. Crit Rev Biochem Mol Biol (2011) 1.13
Duplex RNA activated ATPases (DRAs): platforms for RNA sensing, signaling and processing. RNA Biol (2012) 1.10
MDA5 and LGP2: accomplices and antagonists of antiviral signal transduction. J Virol (2014) 0.90
The laboratory of genetics and physiology 2: emerging insights into the controversial functions of this RIG-I-like receptor. Biomed Res Int (2014) 0.84
Interferon induction by RNA viruses and antagonism by viral pathogens. Viruses (2014) 0.84
Host-Viral Interactions: Role of Pattern Recognition Receptors (PRRs) in Human Pneumovirus Infections. Pathogens (2013) 0.82
Negative regulators of the RIG-I-like receptor signaling pathway. Eur J Immunol (2017) 0.76
Invertebrate Iridescent Virus 6, a DNA Virus, Stimulates a Mammalian Innate Immune Response through RIG-I-Like Receptors. PLoS One (2016) 0.75
Nucleic acid sensing and innate immunity: signaling pathways controlling viral pathogenesis and autoimmunity. Curr Clin Microbiol Rep (2016) 0.75
Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation. Nat Genet (1999) 8.17
FcR gamma chain deletion results in pleiotrophic effector cell defects. Cell (1994) 7.66
Caveolin-1 null mice are viable but show evidence of hyperproliferative and vascular abnormalities. J Biol Chem (2001) 7.03
Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors. Science (2000) 6.44
KSHV antibodies among Americans, Italians and Ugandans with and without Kaposi's sarcoma. Nat Med (1996) 5.96
Temporal control of gene expression in transgenic mice by a tetracycline-responsive promoter. Proc Natl Acad Sci U S A (1994) 5.71
Chromatin structure and protein binding in the putative regulatory region of the c-myc gene in Burkitt lymphoma. Cell (1984) 5.61
Stat5a is mandatory for adult mammary gland development and lactogenesis. Genes Dev (1997) 5.57
Influenza A virus NS1 protein prevents activation of NF-kappaB and induction of alpha/beta interferon. J Virol (2000) 5.44
The mammary pathology of genetically engineered mice: the consensus report and recommendations from the Annapolis meeting. Oncogene (2000) 4.90
Cre-mediated gene deletion in the mammary gland. Nucleic Acids Res (1997) 4.89
American College of Rheumatology classification criteria for Sjögren's syndrome: a data-driven, expert consensus approach in the Sjögren's International Collaborative Clinical Alliance cohort. Arthritis Care Res (Hoboken) (2012) 4.82
Live attenuated malaria vaccine designed to protect through hepatic CD8⁺ T cell immunity. Science (2011) 4.72
A 1.5 million-base pair inversion polymorphism in families with Williams-Beuren syndrome. Nat Genet (2001) 4.58
Dicistronic targeting constructs: reporters and modifiers of mammalian gene expression. Proc Natl Acad Sci U S A (1994) 4.44
Seroepidemiology for MERS coronavirus using microneutralisation and pseudoparticle virus neutralisation assays reveal a high prevalence of antibody in dromedary camels in Egypt, June 2013. Euro Surveill (2013) 4.37
Neurotoxicity induces cleavage of p35 to p25 by calpain. Nature (2000) 4.31
The effects of frequent nocturnal home hemodialysis: the Frequent Hemodialysis Network Nocturnal Trial. Kidney Int (2011) 4.27
Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease. Nat Med (2000) 4.18
15-deoxy-delta 12,14-prostaglandin J2 inhibits multiple steps in the NF-kappa B signaling pathway. Proc Natl Acad Sci U S A (2000) 3.89
Antibodies to human c-myc oncogene product: evidence of an evolutionarily conserved protein induced during cell proliferation. Science (1984) 3.63
Homer binds a novel proline-rich motif and links group 1 metabotropic glutamate receptors with IP3 receptors. Neuron (1998) 3.59
Spatial and temporal expression of the Cre gene under the control of the MMTV-LTR in different lines of transgenic mice. Transgenic Res (2001) 3.45
Assembly of the mitochondrial membrane system: sequences of yeast mitochondrial valine and an unusual threonine tRNA gene. Cell (1979) 3.39
Isolation and genetic characterization of human KB cell lines resistant to multiple drugs. Somat Cell Mol Genet (1985) 3.23
Crystal structure and functional analysis of the HERG potassium channel N terminus: a eukaryotic PAS domain. Cell (1998) 3.22
O-Linked GlcNAc transferase is a conserved nucleocytoplasmic protein containing tetratricopeptide repeats. J Biol Chem (1997) 3.16
Codon recognition rules in yeast mitochondria. Proc Natl Acad Sci U S A (1980) 3.11
High-dose intravenous immune globulin for stiff-person syndrome. N Engl J Med (2001) 3.04
Conditional expression and signaling of a specifically designed Gi-coupled receptor in transgenic mice. Nat Biotechnol (1999) 3.04
Middle East Respiratory Syndrome (MERS) coronavirus seroprevalence in domestic livestock in Saudi Arabia, 2010 to 2013. Euro Surveill (2013) 2.99
Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease. Nature (1999) 2.97
The variability in activity of the universally expressed human cytomegalovirus immediate early gene 1 enhancer/promoter in transgenic mice. Nucleic Acids Res (1991) 2.93
Evidence for in vivo but not in vitro expression of a Borrelia burgdorferi outer surface protein F (OspF) homologue. Mol Microbiol (1995) 2.92
Binding of transcription factors and creation of a large nucleoprotein complex on the human cytomegalovirus enhancer. Proc Natl Acad Sci U S A (1987) 2.89
O-linked N-acetylglucosamine is attached to proteins of the nuclear pore. Evidence for cytoplasmic and nucleoplasmic glycoproteins. J Biol Chem (1987) 2.88
Alcohol drinking and all cancer mortality: a meta-analysis. Ann Oncol (2012) 2.83
Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumorigenesis. Nat Genet (2001) 2.82
Cloning and expression of Stat5 and an additional homologue (Stat5b) involved in prolactin signal transduction in mouse mammary tissue. Proc Natl Acad Sci U S A (1995) 2.79
Identification of the paromomycin-resistance mutation in the 15 S rRNA gene of yeast mitochondria. J Biol Chem (1982) 2.70
Ribosomal protein S7 as a novel modulator of p53-MDM2 interaction: binding to MDM2, stabilization of p53 protein, and activation of p53 function. Oncogene (2007) 2.68
Caveolin-3 null mice show a loss of caveolae, changes in the microdomain distribution of the dystrophin-glycoprotein complex, and t-tubule abnormalities. J Biol Chem (2001) 2.62
Nuclear factor 1 interacts with five DNA elements in the promoter region of the human cytomegalovirus major immediate early gene. EMBO J (1986) 2.62
Fusion of two novel genes, RBM15 and MKL1, in the t(1;22)(p13;q13) of acute megakaryoblastic leukemia. Nat Genet (2001) 2.55
Mammary epithelial cells undergo secretory differentiation in cycling virgins but require pregnancy for the establishment of terminal differentiation. Development (1995) 2.50
Morphologic characterization of the pathway of transferrin endocytosis and recycling in human KB cells. Proc Natl Acad Sci U S A (1984) 2.42
Ketamine anesthesia during the first week of life can cause long-lasting cognitive deficits in rhesus monkeys. Neurotoxicol Teratol (2011) 2.41
Deregulation of cell growth by the K1 gene of Kaposi's sarcoma-associated herpesvirus. Nat Med (1998) 2.38
The gut as a portal of entry for bacteremia. Role of protein malnutrition. Ann Surg (1987) 2.38
The C/EBPbeta transcription factor regulates epithelial cell proliferation and differentiation in the mammary gland. Genes Dev (1998) 2.25
Ha-ras oncogene expression directed by a milk protein gene promoter: tissue specificity, hormonal regulation, and tumor induction in transgenic mice. Proc Natl Acad Sci U S A (1987) 2.23
The clinical spectrum of anti-GAD antibody-positive patients with stiff-person syndrome. Neurology (2000) 2.20
A clustering approach to multireference alignment of single-particle projections in electron microscopy. J Struct Biol (2010) 2.19
CREB-binding protein sequestration by expanded polyglutamine. Hum Mol Genet (2000) 2.18
Patch clamp detection of transcription factor translocation along the nuclear pore complex channel. J Membr Biol (1995) 2.17
Double-blind and placebo-controlled study of lithium for adolescent bipolar disorders with secondary substance dependency. J Am Acad Child Adolesc Psychiatry (1998) 2.16
Characterization of human tracheal epithelial cells transformed by an origin-defective simian virus 40. Proc Natl Acad Sci U S A (1988) 2.15
Accessory protein facilitated CFTR-CFTR interaction, a molecular mechanism to potentiate the chloride channel activity. Cell (2000) 2.15
Borrelia burgdorferi supercoiled plasmids encode multicopy tandem open reading frames and a lipoprotein gene family. J Bacteriol (1996) 2.14
Lung cancer proliferation correlates with [F-18]fluorodeoxyglucose uptake by positron emission tomography. Clin Cancer Res (2000) 2.13
Conditional deletion of the Bcl-x gene from erythroid cells results in hemolytic anemia and profound splenomegaly. Development (2000) 2.10
Cytoplasmic dynein function is essential in Drosophila melanogaster. Genetics (1996) 2.10
Primary sequence and heterologous expression of nuclear pore glycoprotein p62. J Cell Biol (1990) 2.09
Dietetic guidelines on food and nutrition in the secondary prevention of cardiovascular disease - evidence from systematic reviews of randomized controlled trials (second update, January 2006). J Hum Nutr Diet (2006) 2.09
Interaction of protein with DNA in vitro. Methods Enzymol (1987) 2.07
Functional expression of O-linked GlcNAc transferase. Domain structure and substrate specificity. J Biol Chem (2000) 2.05
Use of the UGA terminator as a tryptophan codon in yeast mitochondria. Proc Natl Acad Sci U S A (1979) 2.05
Signal transducer and activator of transcription (Stat) 5 controls the proliferation and differentiation of mammary alveolar epithelium. J Cell Biol (2001) 2.05
An indirect effect of Stat5a in IL-2-induced proliferation: a critical role for Stat5a in IL-2-mediated IL-2 receptor alpha chain induction. Immunity (1997) 2.01
High-affinity binding site for a specific nuclear protein in the human IgM gene. Nature (1985) 2.00
Regulation of transport of the dopamine D1 receptor by a new membrane-associated ER protein. Nat Cell Biol (2001) 1.99
MicroRNA-221/222 confers breast cancer fulvestrant resistance by regulating multiple signaling pathways. Oncogene (2010) 1.97
Solution structure of the extended neuronal nitric oxide synthase PDZ domain complexed with an associated peptide. Nat Struct Biol (1999) 1.95
Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)Kgamma. Nature (2000) 1.93
Conditional gene expression in secretory tissues and skin of transgenic mice using the MMTV-LTR and the tetracycline responsive system. J Cell Biochem (1995) 1.93
Matrix-attachment regions can impart position-independent regulation of a tissue-specific gene in transgenic mice. Proc Natl Acad Sci U S A (1992) 1.92
PR39, a peptide regulator of angiogenesis. Nat Med (2000) 1.90
Expression of a truncated Int3 gene in developing secretory mammary epithelium specifically retards lobular differentiation resulting in tumorigenesis. Cancer Res (1996) 1.90
Modified sutureless sclerotomies in pars plana vitrectomy. Am J Ophthalmol (1999) 1.89
Transgenic factor VIII: the milky way and beyond. Nat Biotechnol (1997) 1.88
Activation of Stat5a and Stat5b by tyrosine phosphorylation is tightly linked to mammary gland differentiation. Mol Endocrinol (1996) 1.86
Targeting expression of a transforming growth factor beta 1 transgene to the pregnant mammary gland inhibits alveolar development and lactation. EMBO J (1993) 1.86
Expression of a whey acidic protein transgene during mammary development. Evidence for different mechanisms of regulation during pregnancy and lactation. J Biol Chem (1991) 1.84
Identification of an immunoreceptor tyrosine-based activation motif of K1 transforming protein of Kaposi's sarcoma-associated herpesvirus. Mol Cell Biol (1998) 1.84
Clinicopathological features of Churg-Strauss syndrome-associated neuropathy. Brain (1999) 1.84
Synectin, syndecan-4 cytoplasmic domain binding PDZ protein, inhibits cell migration. J Cell Physiol (2000) 1.82
Time-sensitive reversal of hyperplasia in transgenic mice expressing SV40 T antigen. Science (1996) 1.82
Mammary-derived signals activate programmed cell death during the first stage of mammary gland involution. Proc Natl Acad Sci U S A (1997) 1.80
Heme oxygenase-1 protects against radiocontrast-induced acute kidney injury by regulating anti-apoptotic proteins. Kidney Int (2007) 1.80
Calreticulin Is a receptor for nuclear export. J Cell Biol (2001) 1.79
Kinetics of transit of transferrin and epidermal growth factor through clathrin-coated membranes. Cell (1984) 1.78
Specific interactions between transcription factors and the promoter-regulatory region of the human cytomegalovirus major immediate-early gene. J Virol (1988) 1.78
Phorbol esters induce transient internalization without degradation of unoccupied epidermal growth factor receptors. Proc Natl Acad Sci U S A (1985) 1.77
Hemorrhagic shock induces bacterial translocation from the gut. J Trauma (1988) 1.77