Published in Cancer Res on March 01, 2002
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Potent antitumor activity of a urokinase-activated engineered anthrax toxin. Proc Natl Acad Sci U S A (2003) 1.38
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PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity. J Cell Biol (2014) 3.12
JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis. Neuron (2003) 2.86
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The soluble form of Bax regulates mitochondrial fusion via MFN2 homotypic complexes. Mol Cell (2011) 2.43
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Endophilin B1 is required for the maintenance of mitochondrial morphology. J Cell Biol (2004) 2.28
Anti-apoptotic MCL-1 localizes to the mitochondrial matrix and couples mitochondrial fusion to respiration. Nat Cell Biol (2012) 2.25
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PINK1 drives Parkin self-association and HECT-like E3 activity upstream of mitochondrial binding. J Cell Biol (2013) 2.04
Control of mitochondrial permeability by Bcl-2 family members. Biochim Biophys Acta (2004) 2.00
A chemical inhibitor of DRP1 uncouples mitochondrial fission and apoptosis. Mol Cell (2008) 1.94
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Hsp90-Cdc37 chaperone complex regulates Ulk1- and Atg13-mediated mitophagy. Mol Cell (2011) 1.91
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Cytomegalovirus cell death suppressor vMIA blocks Bax- but not Bak-mediated apoptosis by binding and sequestering Bax at mitochondria. Proc Natl Acad Sci U S A (2004) 1.85
Parkin-induced mitophagy in the pathogenesis of Parkinson disease. Autophagy (2009) 1.82
Targeting mitochondrial dysfunction: role for PINK1 and Parkin in mitochondrial quality control. Antioxid Redox Signal (2011) 1.82
Bcl-x(L) sequesters its C-terminal membrane anchor in soluble, cytosolic homodimers. EMBO J (2004) 1.77
The solution structure of human mitochondria fission protein Fis1 reveals a novel TPR-like helix bundle. J Mol Biol (2003) 1.70
PINK1 is degraded through the N-end rule pathway. Autophagy (2013) 1.63
Polyubiquitin-sensor proteins reveal localization and linkage-type dependence of cellular ubiquitin signaling. Nat Methods (2012) 1.62
Regulating mitochondrial outer membrane proteins by ubiquitination and proteasomal degradation. Curr Opin Cell Biol (2011) 1.62
Bid, but not Bax, regulates VDAC channels. J Biol Chem (2004) 1.57
Instability of the mitofusin Fzo1 regulates mitochondrial morphology during the mating response of the yeast Saccharomyces cerevisiae. J Biol Chem (2005) 1.54
Parkin is a lipid-responsive regulator of fat uptake in mice and mutant human cells. J Clin Invest (2011) 1.52
Loss of MARCH5 mitochondrial E3 ubiquitin ligase induces cellular senescence through dynamin-related protein 1 and mitofusin 1. J Cell Sci (2010) 1.47
The permeability transition pore signals apoptosis by directing Bax translocation and multimerization. FASEB J (2002) 1.46
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The accumulation of misfolded proteins in the mitochondrial matrix is sensed by PINK1 to induce PARK2/Parkin-mediated mitophagy of polarized mitochondria. Autophagy (2013) 1.31
Entry into cells and selective degradation of tRNAs by a cytotoxic member of the RNase A family. J Biol Chem (2002) 1.27
Novel structure of the N terminus in yeast Fis1 correlates with a specialized function in mitochondrial fission. J Biol Chem (2005) 1.27
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Pseudomonas exotoxin A-mediated apoptosis is Bak dependent and preceded by the degradation of Mcl-1. Mol Cell Biol (2010) 1.23
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Cytomegalovirus proteins vMIA and m38.5 link mitochondrial morphogenesis to Bcl-2 family proteins. J Virol (2008) 1.09
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Mitochondrial Rab GAPs govern autophagosome biogenesis during mitophagy. Elife (2014) 1.06
A systematic search for endoplasmic reticulum (ER) membrane-associated RING finger proteins identifies Nixin/ZNRF4 as a regulator of calnexin stability and ER homeostasis. J Biol Chem (2011) 1.04
Involvement of mitochondrial dynamics in the segregation of mitochondrial matrix proteins during stationary phase mitophagy. Nat Commun (2013) 1.01
Jak3-independent trafficking of the common gamma chain receptor subunit: chaperone function of Jaks revisited. Mol Cell Biol (2004) 1.01
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Coupling mitochondrial and cell division. Nat Cell Biol (2011) 0.98
Mutations in Fis1 disrupt orderly disposal of defective mitochondria. Mol Biol Cell (2013) 0.98
Antiapoptotic action of hypoxia-inducible factor-1 alpha in human endothelial cells. Lab Invest (2004) 0.96
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Atypical mitochondrial fission upon bacterial infection. Proc Natl Acad Sci U S A (2013) 0.95
Structural mechanism of Bax inhibition by cytomegalovirus protein vMIA. Proc Natl Acad Sci U S A (2012) 0.94
Ubiquitin ligase RNF167 regulates AMPA receptor-mediated synaptic transmission. Proc Natl Acad Sci U S A (2012) 0.93
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Bax activates endophilin B1 oligomerization and lipid membrane vesiculation. J Biol Chem (2009) 0.91
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Scission, spores, and apoptosis: a proposal for the evolutionary origin of mitochondria in cell death induction. Biochem Biophys Res Commun (2003) 0.90
PINK1 rendered temperature sensitive by disease-associated and engineered mutations. Hum Mol Genet (2013) 0.87
Expression of vascular endothelial growth factors and their receptors in and around intracranial arteriovenous malformations. Neurosurgery (2002) 0.85
A clinically complex form of dominant optic atrophy (OPA8) maps on chromosome 16. Hum Mol Genet (2011) 0.83
PINK1 and Parkin flag Miro to direct mitochondrial traffic. Cell (2011) 0.81
Neurodegeneration: Trouble in the cell's powerhouse. Nature (2012) 0.80
Rapid resolution of hydrocephalus due to simultaneous movements of hematoma in the trigono-occipital horn and the aqueduct. Neurol India (2009) 0.79
Bcl-xL and caspase inhibition increase the survival of rat oxytocin and vasopressin magnocellular neurons in organotypic culture. Exp Neurol (2006) 0.79
Endosome fusion induced by diphtheria toxin translocation domain. Proc Natl Acad Sci U S A (2008) 0.79
The cytokine, granulocyte-macrophage colony-stimulating factor (GM-CSF), can deliver Bcl-XL as an extracellular fusion protein to protect cells from apoptosis and retain differentiation induction. J Biol Chem (2007) 0.78
A chimeric protein induces tumor cell apoptosis by delivering the human Bcl-2 family BH3-only protein Bad. Biochemistry (2005) 0.78
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Make or break for mitochondria. Elife (2013) 0.76
Mitochondrial disease: mtDNA and protein segregation mysteries in iPSCs. Curr Biol (2013) 0.76
Sequestration and autophagy of mitochondria do not cut proteins across the board. Proc Natl Acad Sci U S A (2013) 0.75
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