Published in J Cell Biol on January 14, 2013
Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. Nature (2013) 3.57
Ubiquitin is phosphorylated by PINK1 to activate parkin. Nature (2014) 3.36
PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity. J Cell Biol (2014) 3.12
The roles of PINK1, parkin, and mitochondrial fidelity in Parkinson's disease. Neuron (2015) 2.82
Quantitative proteomics reveal a feedforward mechanism for mitochondrial PARKIN translocation and ubiquitin chain synthesis. Mol Cell (2014) 2.52
Structure of the human Parkin ligase domain in an autoinhibited state. EMBO J (2013) 2.38
RING-type E3 ligases: master manipulators of E2 ubiquitin-conjugating enzymes and ubiquitination. Biochim Biophys Acta (2013) 1.64
Parkin mitochondrial translocation is achieved through a novel catalytic activity coupled mechanism. Cell Res (2013) 1.59
Parkin-catalyzed ubiquitin-ester transfer is triggered by PINK1-dependent phosphorylation. J Biol Chem (2013) 1.50
Structure of HHARI, a RING-IBR-RING ubiquitin ligase: autoinhibition of an Ariadne-family E3 and insights into ligation mechanism. Structure (2013) 1.48
Defining roles of PARKIN and ubiquitin phosphorylation by PINK1 in mitochondrial quality control using a ubiquitin replacement strategy. Proc Natl Acad Sci U S A (2015) 1.26
Organellophagy: eliminating cellular building blocks via selective autophagy. J Cell Biol (2014) 1.25
Phosphorylated ubiquitin chain is the genuine Parkin receptor. J Cell Biol (2015) 1.24
Phosphorylation of mitochondrial polyubiquitin by PINK1 promotes Parkin mitochondrial tethering. PLoS Genet (2014) 1.20
USP8 regulates mitophagy by removing K6-linked ubiquitin conjugates from parkin. EMBO J (2014) 1.20
Phosphorylation of Parkin at Serine65 is essential for activation: elaboration of a Miro1 substrate-based assay of Parkin E3 ligase activity. Open Biol (2014) 1.19
After the banquet: mitochondrial biogenesis, mitophagy, and cell survival. Autophagy (2013) 1.17
Parkin- and PINK1-Dependent Mitophagy in Neurons: Will the Real Pathway Please Stand Up? Front Neurol (2013) 1.17
The different facets of organelle interplay-an overview of organelle interactions. Front Cell Dev Biol (2015) 1.16
RBR E3 ubiquitin ligases: new structures, new insights, new questions. Biochem J (2014) 1.13
Mitochondrial quality control and communications with the nucleus are important in maintaining mitochondrial function and cell health. Biochim Biophys Acta (2013) 1.10
The three 'P's of mitophagy: PARKIN, PINK1, and post-translational modifications. Genes Dev (2015) 1.08
Structural and functional insights to ubiquitin-like protein conjugation. Annu Rev Biophys (2014) 1.07
Mitochondrial Rab GAPs govern autophagosome biogenesis during mitophagy. Elife (2014) 1.06
A specific subset of E2 ubiquitin-conjugating enzymes regulate Parkin activation and mitophagy differently. J Cell Sci (2014) 1.04
PINK1 triggers autocatalytic activation of Parkin to specify cell fate decisions. Curr Biol (2014) 1.02
Quantifying ubiquitin signaling. Mol Cell (2015) 1.02
Mitochondrial dysfunction and mitophagy: the beginning and end to diabetic nephropathy? Br J Pharmacol (2014) 1.02
Involvement of mitochondrial dynamics in the segregation of mitochondrial matrix proteins during stationary phase mitophagy. Nat Commun (2013) 1.01
Phosphorylation by PINK1 releases the UBL domain and initializes the conformational opening of the E3 ubiquitin ligase Parkin. PLoS Comput Biol (2014) 1.00
Conformational rearrangements in the pro-apoptotic protein, Bax, as it inserts into mitochondria: a cellular death switch. J Biol Chem (2014) 0.99
Structure and Function of Parkin, PINK1, and DJ-1, the Three Musketeers of Neuroprotection. Front Neurol (2013) 0.99
PINK1-mediated phosphorylation of Parkin boosts Parkin activity in Drosophila. PLoS Genet (2014) 0.99
Mechanisms of drug-induced liver injury. Clin Liver Dis (2013) 0.99
Role of p62/SQSTM1 in liver physiology and pathogenesis. Exp Biol Med (Maywood) (2013) 0.96
BECN1 is involved in the initiation of mitophagy: it facilitates PARK2 translocation to mitochondria. Autophagy (2014) 0.95
Brain iron homeostasis: from molecular mechanisms to clinical significance and therapeutic opportunities. Antioxid Redox Signal (2013) 0.94
Defects in GABA metabolism affect selective autophagy pathways and are alleviated by mTOR inhibition. EMBO Mol Med (2014) 0.93
Evaluation of Models of Parkinson's Disease. Front Neurosci (2016) 0.90
Quality control gone wrong: mitochondria, lysosomal storage disorders and neurodegeneration. Br J Pharmacol (2014) 0.90
Dynamic survey of mitochondria by ubiquitin. EMBO Rep (2014) 0.90
RBR E3-ligases at work. EMBO Rep (2014) 0.89
Nilotinib-induced autophagic changes increase endogenous parkin level and ubiquitination, leading to amyloid clearance. J Mol Med (Berl) (2013) 0.89
Molecular events underlying Parkinson's disease - an interwoven tapestry. Front Neurol (2013) 0.86
Compact Parkin only: insights into the structure of an autoinhibited ubiquitin ligase. EMBO J (2013) 0.86
MitoNEET-Parkin Effects in Pancreatic α- and β-Cells, Cellular Survival, and Intrainsular Cross Talk. Diabetes (2016) 0.85
Molecular insights into RBR E3 ligase ubiquitin transfer mechanisms. EMBO Rep (2016) 0.85
The ubiquitin signal and autophagy: an orchestrated dance leading to mitochondrial degradation. EMBO Rep (2016) 0.84
Activation of the E3 ubiquitin ligase Parkin. Biochem Soc Trans (2015) 0.84
Ataxin-3 and its e3 partners: implications for machado-joseph disease. Front Neurol (2013) 0.83
Specificity and disease in the ubiquitin system. Biochem Soc Trans (2016) 0.82
Site-specific Interaction Mapping of Phosphorylated Ubiquitin to Uncover Parkin Activation. J Biol Chem (2015) 0.82
Ubiquitination increases parkin activity to promote autophagic α-synuclein clearance. PLoS One (2013) 0.82
Probes of ubiquitin E3 ligases enable systematic dissection of parkin activation. Nat Chem Biol (2016) 0.81
Structural and Functional Impact of Parkinson Disease-Associated Mutations in the E3 Ubiquitin Ligase Parkin. Hum Mutat (2015) 0.81
Phosphorylated ubiquitin: a new shade of PINK1 in Parkin activation. Cell Res (2014) 0.81
Pink1, the first ubiquitin kinase. EMBO J (2014) 0.81
The principal PINK1 and Parkin cellular events triggered in response to dissipation of mitochondrial membrane potential occur in primary neurons. Genes Cells (2013) 0.80
Parkin structure and function. FEBS J (2015) 0.80
Ataxin-3 is a multivalent ligand for the parkin Ubl domain. Biochemistry (2013) 0.78
A polyubiquitin chain reaction: parkin recruitment to damaged mitochondria. PLoS Genet (2015) 0.78
Parkin elimination of mitochondria is important for maintenance of lens epithelial cell ROS levels and survival upon oxidative stress exposure. Biochim Biophys Acta (2016) 0.78
Parkin promotes proteasomal degradation of p62: implication of selective vulnerability of neuronal cells in the pathogenesis of Parkinson's disease. Protein Cell (2016) 0.77
PINK1, Parkin, and Mitochondrial Quality Control: What can we Learn about Parkinson's Disease Pathobiology? J Parkinsons Dis (2016) 0.76
Phospho-ubiquitin: upending the PINK-Parkin-ubiquitin cascade. J Biochem (2016) 0.76
Interaction between RING1 (R1) and the Ubiquitin-like (UBL) Domains Is Critical for the Regulation of Parkin Activity. J Biol Chem (2015) 0.76
Phospho-ubiquitin-PARK2 complex as a marker for mitophagy defects. Autophagy (2016) 0.75
Parkin-phosphoubiquitin complex reveals cryptic ubiquitin-binding site required for RBR ligase activity. Nat Struct Mol Biol (2017) 0.75
Miro phosphorylation sites regulate Parkin recruitment and mitochondrial motility. Proc Natl Acad Sci U S A (2016) 0.75
PINK1-dependent phosphorylation of PINK1 and Parkin is essential for mitochondrial quality control. Cell Death Dis (2016) 0.75
Structural insights into Parkin substrate lysine targeting from minimal Miro substrates. Sci Rep (2016) 0.75
Quantitative proteomic analysis of Parkin substrates in Drosophila neurons. Mol Neurodegener (2017) 0.75
Mitochondrial Reactive Oxygen Species and Kidney Hypoxia in the Development of Diabetic Nephropathy. Front Physiol (2017) 0.75
Structure-guided mutagenesis reveals a hierarchical mechanism of Parkin activation. Nat Commun (2017) 0.75
UbMES and UbFluor: Novel Probes For RBR E3 Ubiquitin Ligase PARKIN. J Biol Chem (2017) 0.75
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature (1998) 21.49
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy. J Cell Biol (2008) 17.81
Hereditary early-onset Parkinson's disease caused by mutations in PINK1. Science (2004) 15.91
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1. Nat Cell Biol (2010) 12.26
Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin. Nature (2006) 11.91
PINK1 is selectively stabilized on impaired mitochondria to activate Parkin. PLoS Biol (2010) 11.85
Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin. Nature (2006) 11.81
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy. Proc Natl Acad Sci U S A (2009) 8.25
PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy. J Cell Biol (2010) 7.62
Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin. J Cell Biol (2010) 5.94
Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin. Proc Natl Acad Sci U S A (2006) 5.78
Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin. Proc Natl Acad Sci U S A (2010) 5.17
Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy. Hum Mol Genet (2011) 4.41
Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability. Proc Natl Acad Sci U S A (2005) 4.22
Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy. Hum Mol Genet (2010) 3.77
Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL. J Cell Biol (2010) 3.68
PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65. Open Biol (2012) 3.42
UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids. Nature (2011) 3.40
The mitochondrial fusion-promoting factor mitofusin is a substrate of the PINK1/parkin pathway. PLoS One (2010) 3.16
Fluorescence correlation spectroscopy: novel variations of an established technique. Annu Rev Biophys Biomol Struct (2007) 3.00
Parkin mediates proteasome-dependent protein degradation and rupture of the outer mitochondrial membrane. J Biol Chem (2011) 2.99
E2 interaction and dimerization in the crystal structure of TRAF6. Nat Struct Mol Biol (2009) 2.79
Autoregulation of Parkin activity through its ubiquitin-like domain. EMBO J (2011) 2.75
Role of PINK1 binding to the TOM complex and alternate intracellular membranes in recruitment and activation of the E3 ligase Parkin. Dev Cell (2012) 2.52
Fluorescence correlation spectroscopy in living cells. Nat Methods (2007) 2.51
Identification of a novel mitochondrial protein ("mitoNEET") cross-linked specifically by a thiazolidinedione photoprobe. Am J Physiol Endocrinol Metab (2003) 2.51
Alterations in the common fragile site gene Parkin in ovarian and other cancers. Oncogene (2003) 2.44
PINK1 cleavage at position A103 by the mitochondrial protease PARL. Hum Mol Genet (2010) 2.30
Rhomboid-7 and HtrA2/Omi act in a common pathway with the Parkinson's disease factors Pink1 and Parkin. Dis Model Mech (2008) 2.29
Genetic etiology of Parkinson disease associated with mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 genes: a mutation update. Hum Mutat (2010) 2.29
Biochemical analysis of Parkinson's disease-causing variants of Parkin, an E3 ubiquitin-protein ligase with monoubiquitylation capacity. Hum Mol Genet (2006) 2.24
MitoNEET-driven alterations in adipocyte mitochondrial activity reveal a crucial adaptive process that preserves insulin sensitivity in obesity. Nat Med (2012) 2.13
Mitochondrial quality control mediated by PINK1 and Parkin: links to parkinsonism. Cold Spring Harb Perspect Biol (2012) 2.10
Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment. EMBO Rep (2012) 2.08
The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking. J Neurochem (2011) 1.93
LUBAC synthesizes linear ubiquitin chains via a thioester intermediate. EMBO Rep (2012) 1.82
Control of biochemical reactions through supramolecular RING domain self-assembly. Proc Natl Acad Sci U S A (2002) 1.63
The Prp19 U-box crystal structure suggests a common dimeric architecture for a class of oligomeric E3 ubiquitin ligases. Biochemistry (2006) 1.38
Fluorescence correlation spectroscopy investigation of a GFP mutant-enhanced cyan fluorescent protein and its tubulin fusion in living cells with two-photon excitation. J Biomed Opt (2004) 1.22
Using linkage-specific monoclonal antibodies to analyze cellular ubiquitylation. Methods Mol Biol (2012) 0.84
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy. J Cell Biol (2008) 17.81
PINK1 is selectively stabilized on impaired mitochondria to activate Parkin. PLoS Biol (2010) 11.85
Mechanisms of mitophagy. Nat Rev Mol Cell Biol (2011) 10.66
Mitochondrial dynamics and apoptosis. Genes Dev (2008) 6.07
Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin. J Cell Biol (2010) 5.94
Roles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, and Opa1 in apoptosis. Mol Biol Cell (2004) 5.94
Role of Bax and Bak in mitochondrial morphogenesis. Nature (2006) 5.25
Spatial and temporal association of Bax with mitochondrial fission sites, Drp1, and Mfn2 during apoptosis. J Cell Biol (2002) 5.01
Mitochondria in apoptosis: Bcl-2 family members and mitochondrial dynamics. Dev Cell (2011) 4.91
Nitric oxide-induced mitochondrial fission is regulated by dynamin-related GTPases in neurons. EMBO J (2006) 4.43
Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells. J Cell Biol (2010) 3.91
The mitochondrial E3 ubiquitin ligase MARCH5 is required for Drp1 dependent mitochondrial division. J Cell Biol (2007) 3.83
Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL. J Cell Biol (2010) 3.68
p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both. Autophagy (2010) 3.68
Quantitation of mitochondrial dynamics by photolabeling of individual organelles shows that mitochondrial fusion is blocked during the Bax activation phase of apoptosis. J Cell Biol (2004) 3.55
The role of mitochondria in apoptosis*. Annu Rev Genet (2009) 3.44
Drp-1-dependent division of the mitochondrial network blocks intraorganellar Ca2+ waves and protects against Ca2+-mediated apoptosis. Mol Cell (2004) 3.28
Bcl-x(L) retrotranslocates Bax from the mitochondria into the cytosol. Cell (2011) 3.23
PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity. J Cell Biol (2014) 3.12
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy. Nature (2015) 2.96
JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis. Neuron (2003) 2.86
Mitofusin-1 protein is a generally expressed mediator of mitochondrial fusion in mammalian cells. J Cell Sci (2003) 2.68
OPA1 mutations associated with dominant optic atrophy impair oxidative phosphorylation and mitochondrial fusion. Brain (2008) 2.57
Role of PINK1 binding to the TOM complex and alternate intracellular membranes in recruitment and activation of the E3 ligase Parkin. Dev Cell (2012) 2.52
The soluble form of Bax regulates mitochondrial fusion via MFN2 homotypic complexes. Mol Cell (2011) 2.43
Loss of Bif-1 suppresses Bax/Bak conformational change and mitochondrial apoptosis. Mol Cell Biol (2005) 2.31
Endophilin B1 is required for the maintenance of mitochondrial morphology. J Cell Biol (2004) 2.28
Anti-apoptotic MCL-1 localizes to the mitochondrial matrix and couples mitochondrial fusion to respiration. Nat Cell Biol (2012) 2.25
Mitochondrial fission and fusion mediators, hFis1 and OPA1, modulate cellular senescence. J Biol Chem (2007) 2.22
Mitochondrial release of AIF and EndoG requires caspase activation downstream of Bax/Bak-mediated permeabilization. EMBO J (2003) 2.16
How do Bax and Bak lead to permeabilization of the outer mitochondrial membrane? Curr Opin Cell Biol (2006) 2.14
Parkin overexpression selects against a deleterious mtDNA mutation in heteroplasmic cybrid cells. Proc Natl Acad Sci U S A (2010) 2.10
Control of mitochondrial permeability by Bcl-2 family members. Biochim Biophys Acta (2004) 2.00
A chemical inhibitor of DRP1 uncouples mitochondrial fission and apoptosis. Mol Cell (2008) 1.94
Role of mitochondrial remodeling in programmed cell death in Drosophila melanogaster. Dev Cell (2007) 1.91
Hsp90-Cdc37 chaperone complex regulates Ulk1- and Atg13-mediated mitophagy. Mol Cell (2011) 1.91
PINK1- and Parkin-mediated mitophagy at a glance. J Cell Sci (2012) 1.89
Sumoylation of heterogeneous nuclear ribonucleoproteins, zinc finger proteins, and nuclear pore complex proteins: a proteomic analysis. Proc Natl Acad Sci U S A (2004) 1.85
Cytomegalovirus cell death suppressor vMIA blocks Bax- but not Bak-mediated apoptosis by binding and sequestering Bax at mitochondria. Proc Natl Acad Sci U S A (2004) 1.85
Parkin-induced mitophagy in the pathogenesis of Parkinson disease. Autophagy (2009) 1.82
Targeting mitochondrial dysfunction: role for PINK1 and Parkin in mitochondrial quality control. Antioxid Redox Signal (2011) 1.82
Bcl-x(L) sequesters its C-terminal membrane anchor in soluble, cytosolic homodimers. EMBO J (2004) 1.77
The solution structure of human mitochondria fission protein Fis1 reveals a novel TPR-like helix bundle. J Mol Biol (2003) 1.70
PINK1 is degraded through the N-end rule pathway. Autophagy (2013) 1.63
Polyubiquitin-sensor proteins reveal localization and linkage-type dependence of cellular ubiquitin signaling. Nat Methods (2012) 1.62
Regulating mitochondrial outer membrane proteins by ubiquitination and proteasomal degradation. Curr Opin Cell Biol (2011) 1.62
Bid, but not Bax, regulates VDAC channels. J Biol Chem (2004) 1.57
Instability of the mitofusin Fzo1 regulates mitochondrial morphology during the mating response of the yeast Saccharomyces cerevisiae. J Biol Chem (2005) 1.54
Parkin is a lipid-responsive regulator of fat uptake in mice and mutant human cells. J Clin Invest (2011) 1.52
Loss of MARCH5 mitochondrial E3 ubiquitin ligase induces cellular senescence through dynamin-related protein 1 and mitofusin 1. J Cell Sci (2010) 1.47
The permeability transition pore signals apoptosis by directing Bax translocation and multimerization. FASEB J (2002) 1.46
Stable and controllable RNA interference: Investigating the physiological function of glutathionylated actin. Proc Natl Acad Sci U S A (2003) 1.36
Outer mitochondrial membrane protein degradation by the proteasome. Novartis Found Symp (2007) 1.36
SnapShot: BCL-2 proteins. Cell (2009) 1.33
The accumulation of misfolded proteins in the mitochondrial matrix is sensed by PINK1 to induce PARK2/Parkin-mediated mitophagy of polarized mitochondria. Autophagy (2013) 1.31
Entry into cells and selective degradation of tRNAs by a cytotoxic member of the RNase A family. J Biol Chem (2002) 1.27
Novel structure of the N terminus in yeast Fis1 correlates with a specialized function in mitochondrial fission. J Biol Chem (2005) 1.27
Expression of SUMO-2/3 induced senescence through p53- and pRB-mediated pathways. J Biol Chem (2006) 1.26
Role of the ubiquitin conjugation system in the maintenance of mitochondrial homeostasis. Ann N Y Acad Sci (2008) 1.26
Pseudomonas exotoxin A-mediated apoptosis is Bak dependent and preceded by the degradation of Mcl-1. Mol Cell Biol (2010) 1.23
Role of membrane association and Atg14-dependent phosphorylation in beclin-1-mediated autophagy. Mol Cell Biol (2013) 1.16
MicroRNA-205 regulates the expression of Parkinson's disease-related leucine-rich repeat kinase 2 protein. Hum Mol Genet (2012) 1.11
Cytomegalovirus proteins vMIA and m38.5 link mitochondrial morphogenesis to Bcl-2 family proteins. J Virol (2008) 1.09
IBRDC2, an IBR-type E3 ubiquitin ligase, is a regulatory factor for Bax and apoptosis activation. EMBO J (2010) 1.08
Mitochondrial Rab GAPs govern autophagosome biogenesis during mitophagy. Elife (2014) 1.06
A systematic search for endoplasmic reticulum (ER) membrane-associated RING finger proteins identifies Nixin/ZNRF4 as a regulator of calnexin stability and ER homeostasis. J Biol Chem (2011) 1.04
Involvement of mitochondrial dynamics in the segregation of mitochondrial matrix proteins during stationary phase mitophagy. Nat Commun (2013) 1.01
Jak3-independent trafficking of the common gamma chain receptor subunit: chaperone function of Jaks revisited. Mol Cell Biol (2004) 1.01
Mutations in Fis1 disrupt orderly disposal of defective mitochondria. Mol Biol Cell (2013) 0.98
Coupling mitochondrial and cell division. Nat Cell Biol (2011) 0.98
A general approach for investigating enzymatic pathways and substrates for ubiquitin-like modifiers. Arch Biochem Biophys (2006) 0.98
Mitochondrial fission and fusion. Essays Biochem (2010) 0.96
Atypical mitochondrial fission upon bacterial infection. Proc Natl Acad Sci U S A (2013) 0.95
Disrupted intracellular calcium regulates BACE1 gene expression via nuclear factor of activated T cells 1 (NFAT 1) signaling. Aging Cell (2007) 0.95
Structural mechanism of Bax inhibition by cytomegalovirus protein vMIA. Proc Natl Acad Sci U S A (2012) 0.94
Ubiquitin ligase RNF167 regulates AMPA receptor-mediated synaptic transmission. Proc Natl Acad Sci U S A (2012) 0.93
FAT10 modifies p53 and upregulates its transcriptional activity. Arch Biochem Biophys (2011) 0.92
Extracellular Bad fused to toxin transport domains induces apoptosis. Cancer Res (2002) 0.92
Bax activates endophilin B1 oligomerization and lipid membrane vesiculation. J Biol Chem (2009) 0.91
Mitochondrial fission and fusion and their roles in the heart. J Mol Med (Berl) (2010) 0.91
Mitochondrial Function, Biology, and Role in Disease: A Scientific Statement From the American Heart Association. Circ Res (2016) 0.91
Scission, spores, and apoptosis: a proposal for the evolutionary origin of mitochondria in cell death induction. Biochem Biophys Res Commun (2003) 0.90
PINK1 rendered temperature sensitive by disease-associated and engineered mutations. Hum Mol Genet (2013) 0.87
A clinically complex form of dominant optic atrophy (OPA8) maps on chromosome 16. Hum Mol Genet (2011) 0.83
Analytical approaches for studying transporters, channels and porins. Chem Rev (2012) 0.82
Constitutive JAK2/STAT1 activation regulates endogenous BACE1 expression in neurons. Biochem Biophys Res Commun (2009) 0.81
Z-disc-associated, alternatively spliced, PDZ motif-containing protein (ZASP) mutations in the actin-binding domain cause disruption of skeletal muscle actin filaments in myofibrillar myopathy. J Biol Chem (2014) 0.81