Published in Mamm Genome on April 01, 2002
Integrative genomics: in silico coupling of rat physiology and complex traits with mouse and human data. Genome Res (2004) 1.21
High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence. Genome Res (2004) 1.21
Functional genomics in rodent models of hypertension. J Physiol (2004) 0.92
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Nature (2004) 24.40
The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells. Nat Genet (2006) 20.76
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
Copy number polymorphism in Fcgr3 predisposes to glomerulonephritis in rats and humans. Nature (2006) 9.30
The Systems Biology Graphical Notation. Nat Biotechnol (2009) 8.53
Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease. Nat Genet (2005) 7.82
Finding genes that underlie complex traits. Science (2002) 7.39
An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22. Genomics (2002) 7.10
Genome sequence of the dissimilatory metal ion-reducing bacterium Shewanella oneidensis. Nat Biotechnol (2002) 6.96
A promoter-level mammalian expression atlas. Nature (2014) 6.25
Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides. Nat Genet (2008) 6.06
Progress and prospects in rat genetics: a community view. Nat Genet (2008) 6.01
Comparative full-length genome sequence analysis of 14 SARS coronavirus isolates and common mutations associated with putative origins of infection. Lancet (2003) 5.99
FCGR3B copy number variation is associated with susceptibility to systemic, but not organ-specific, autoimmunity. Nat Genet (2007) 5.93
Common genetic variation near MC4R is associated with waist circumference and insulin resistance. Nat Genet (2008) 5.55
Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease. JAMA (2009) 5.32
Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice. Proc Natl Acad Sci U S A (2006) 5.19
The Rat Genome Database, update 2007--easing the path from disease to data and back again. Nucleic Acids Res (2006) 4.80
Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes. Am J Hum Genet (2008) 4.69
The long-term health consequences of child physical abuse, emotional abuse, and neglect: a systematic review and meta-analysis. PLoS Med (2012) 4.37
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet (2014) 4.13
Genetic loci influencing kidney function and chronic kidney disease. Nat Genet (2010) 3.75
Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci. Nat Genet (2011) 3.46
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet (2011) 3.40
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21
Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. Nat Genet (2011) 3.18
New gene functions in megakaryopoiesis and platelet formation. Nature (2011) 3.14
An ENU-induced mutation of miR-96 associated with progressive hearing loss in mice. Nat Genet (2009) 3.05
A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk. Nature (2010) 2.88
E-learning in medical education in resource constrained low- and middle-income countries. Hum Resour Health (2013) 2.85
Genome-wide computational identification and manual annotation of human long noncoding RNA genes. RNA (2010) 2.85
Heritability and tissue specificity of expression quantitative trait loci. PLoS Genet (2006) 2.80
Seventy-five genetic loci influencing the human red blood cell. Nature (2012) 2.77
Network visualization and analysis of gene expression data using BioLayout Express(3D). Nat Protoc (2009) 2.66
Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. Nat Biotechnol (2004) 2.60
Human long non-coding RNAs promote pluripotency and neuronal differentiation by association with chromatin modifiers and transcription factors. EMBO J (2011) 2.51
Tracking the evolution of the SARS coronavirus using high-throughput, high-density resequencing arrays. Genome Res (2004) 2.47
DACT3 is an epigenetic regulator of Wnt/beta-catenin signaling in colorectal cancer and is a therapeutic target of histone modifications. Cancer Cell (2008) 2.46
Lymphopenia in the BB rat model of type 1 diabetes is due to a mutation in a novel immune-associated nucleotide (Ian)-related gene. Genome Res (2002) 2.45
Rat genetics: attaching physiology and pharmacology to the genome. Nat Rev Genet (2002) 2.44
New insights into the genetic control of gene expression using a Bayesian multi-tissue approach. PLoS Comput Biol (2010) 2.43
Genetic variation in SCN10A influences cardiac conduction. Nat Genet (2010) 2.30
Genome-wide association study identifies variants in TMPRSS6 associated with hemoglobin levels. Nat Genet (2009) 2.19
REST regulates distinct transcriptional networks in embryonic and neural stem cells. PLoS Biol (2008) 2.12
Physiogenomic resources for rat models of heart, lung and blood disorders. Nat Genet (2006) 2.05
Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption. Proc Natl Acad Sci U S A (2011) 2.01
Mutations in a Sar1 GTPase of COPII vesicles are associated with lipid absorption disorders. Nat Genet (2003) 1.99
Assessing unmodified 70-mer oligonucleotide probe performance on glass-slide microarrays. Genome Biol (2003) 1.94
Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells. Science (2015) 1.91
An open-access long oligonucleotide microarray resource for analysis of the human and mouse transcriptomes. Nucleic Acids Res (2006) 1.87
Zic3 is required for maintenance of pluripotency in embryonic stem cells. Mol Biol Cell (2007) 1.77
A coherent approach for analysis of the Illumina HumanMethylation450 BeadChip improves data quality and performance in epigenome-wide association studies. Genome Biol (2015) 1.71
Integrated genomic approaches implicate osteoglycin (Ogn) in the regulation of left ventricular mass. Nat Genet (2008) 1.67
Direct quantitative trait locus mapping of mammalian metabolic phenotypes in diabetic and normoglycemic rat models. Nat Genet (2007) 1.66
Association between cannabis use and psychosis-related outcomes using sibling pair analysis in a cohort of young adults. Arch Gen Psychiatry (2010) 1.66
Common genetic variation near melatonin receptor MTNR1B contributes to raised plasma glucose and increased risk of type 2 diabetes among Indian Asians and European Caucasians. Diabetes (2009) 1.65
Psychotic-like experiences in major depression and anxiety disorders: a population-based survey in young adults. Schizophr Bull (2009) 1.65
Gateways to the FANTOM5 promoter level mammalian expression atlas. Genome Biol (2015) 1.58
Widespread binding of FUS along nascent RNA regulates alternative splicing in the brain. Sci Rep (2012) 1.54
The transcriptional corepressor RIP140 regulates oxidative metabolism in skeletal muscle. Cell Metab (2007) 1.54
Genome sequencing reveals loci under artificial selection that underlie disease phenotypes in the laboratory rat. Cell (2013) 1.53
Genetic aberrations defined by comparative genomic hybridization distinguish long-term from typical survivors of glioblastoma. Cancer Res (2002) 1.52
A logic-based diagram of signalling pathways central to macrophage activation. BMC Syst Biol (2008) 1.49
The long noncoding RNA RMST interacts with SOX2 to regulate neurogenesis. Mol Cell (2013) 1.48
The genome sequence of the spontaneously hypertensive rat: Analysis and functional significance. Genome Res (2010) 1.45
Generation of multipotential mesendodermal progenitors from mouse embryonic stem cells via sustained Wnt pathway activation. J Biol Chem (2007) 1.45
Diffusion-weighted imaging-negative patients with transient ischemic attack are at risk of recurrent transient events. Stroke (2007) 1.44
Changing ethical standards in scientific publication. J Bone Joint Surg Am (2004) 1.42
Long noncoding RNAs in development and disease of the central nervous system. Trends Genet (2013) 1.42
The apolipoprotein B mRNA editing complex performs a multifunctional cycle and suppresses nonsense-mediated decay. EMBO J (2003) 1.42
Systematic biases in DNA copy number originate from isolation procedures. Genome Biol (2013) 1.39
Genetic analysis of autoimmune type 1 diabetes mellitus in mice. 1991. J Immunol (2014) 1.37
Chromosome substitution reveals the genetic basis of Dahl salt-sensitive hypertension and renal disease. Am J Physiol Renal Physiol (2008) 1.37
Laboratory-acquired severe acute respiratory syndrome. N Engl J Med (2004) 1.37
Impact of genomics on research in the rat. Genome Res (2005) 1.37
The genome of a pathogenic rhodococcus: cooptive virulence underpinned by key gene acquisitions. PLoS Genet (2010) 1.36
An oligonucleotide microarray for transcriptome analysis of Schistosoma mansoni and its application/use to investigate gender-associated gene expression. Mol Biochem Parasitol (2005) 1.36
Oct4 switches partnering from Sox2 to Sox17 to reinterpret the enhancer code and specify endoderm. EMBO J (2013) 1.35
The unexplored story of HIV and ageing. Bull World Health Organ (2009) 1.34
Relationship between the tissue-specificity of mouse gene expression and the evolutionary origin and function of the proteins. Genome Biol (2005) 1.33
The genes induced by signal transducer and activators of transcription (STAT)3 and STAT5 in mammary epithelial cells define the roles of these STATs in mammary development. Mol Endocrinol (2005) 1.33
Meta-analysis of lineage-specific gene expression signatures in mouse leukocyte populations. Immunobiology (2010) 1.32
Jund is a determinant of macrophage activation and is associated with glomerulonephritis susceptibility. Nat Genet (2008) 1.31
eQTL Explorer: integrated mining of combined genetic linkage and expression experiments. Bioinformatics (2005) 1.31
Genome-wide meta-analysis for serum calcium identifies significantly associated SNPs near the calcium-sensing receptor (CASR) gene. PLoS Genet (2010) 1.25
The new species concept in dermatophytes-a polyphasic approach. Mycopathologia (2008) 1.24
Chromosomal mapping of the genetic basis of hypertension and renal disease in FHH rats. Am J Physiol Renal Physiol (2007) 1.24
Phylometabonomic patterns of adaptation to high fat diet feeding in inbred mice. PLoS One (2008) 1.23
Coarse particulate matter (PM2.5-10) affects heart rate variability, blood lipids, and circulating eosinophils in adults with asthma. Environ Health Perspect (2007) 1.22
Integrative genomics: in silico coupling of rat physiology and complex traits with mouse and human data. Genome Res (2004) 1.21
Molecular networks in Dahl salt-sensitive hypertension based on transcriptome analysis of a panel of consomic rats. Physiol Genomics (2008) 1.21
High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence. Genome Res (2004) 1.21
Conversion of Sox17 into a pluripotency reprogramming factor by reengineering its association with Oct4 on DNA. Stem Cells (2011) 1.21
Mutational dynamics of the SARS coronavirus in cell culture and human populations isolated in 2003. BMC Infect Dis (2004) 1.21
Improved grading and survival prediction of human astrocytic brain tumors by artificial neural network analysis of gene expression microarray data. Mol Cancer Ther (2008) 1.20
Impaired survival of peripheral T cells, disrupted NK/NKT cell development, and liver failure in mice lacking Gimap5. Blood (2008) 1.19
Identification of renal Cd36 as a determinant of blood pressure and risk for hypertension. Nat Genet (2008) 1.19
Regulation of neural macroRNAs by the transcriptional repressor REST. RNA (2008) 1.18