Published in Am J Respir Crit Care Med on May 01, 2002
Critical role for CXCR2 and CXCR2 ligands during the pathogenesis of ventilator-induced lung injury. J Clin Invest (2002) 3.08
Why are clinicians not embracing the results from pivotal clinical trials in severe sepsis? A bayesian analysis. PLoS One (2008) 1.08
Bench-to-bedside review: adjuncts to mechanical ventilation in patients with acute lung injury. Crit Care (2005) 0.91
Bench-to-bedside review: distal airways in acute respiratory distress syndrome. Crit Care (2007) 0.85
Low tidal volume, high respiratory rate and auto-PEEP: the importance of the basics. Crit Care (2003) 0.82
Mechanisms of ventilator-induced lung injury: the clinician's perspective. Crit Care (2003) 0.77
Application of CO2 waveform in the alveolar recruitment maneuvers of hypoxemic patients during one-lung ventilation. Medicine (Baltimore) (2016) 0.75
Auto-peep with low tidal volume. Am J Respir Crit Care Med (2003) 0.75
End-inspiratory pause prolongation in acute respiratory distress syndrome patients: effects on gas exchange and mechanics. Ann Intensive Care (2016) 0.75
Experimental blunt chest trauma - cardiorespiratory effects of different mechanical ventilation strategies with high positive end-expiratory pressure: a randomized controlled study. BMC Anesthesiol (2016) 0.75
Mathematical modelling to centre low tidal volumes following acute lung injury: a study with biologically variable ventilation. Respir Res (2005) 0.75
Incidence and outcomes of acute lung injury. N Engl J Med (2005) 21.56
Acute respiratory distress syndrome: the Berlin Definition. JAMA (2012) 21.04
Identification of severe acute respiratory syndrome in Canada. N Engl J Med (2003) 14.29
Sepsis in European intensive care units: results of the SOAP study. Crit Care Med (2006) 11.78
One-year outcomes in survivors of the acute respiratory distress syndrome. N Engl J Med (2003) 11.77
Functional disability 5 years after acute respiratory distress syndrome. N Engl J Med (2011) 9.96
Efficacy and safety of corticosteroids for persistent acute respiratory distress syndrome. N Engl J Med (2006) 9.52
Lung recruitment in patients with the acute respiratory distress syndrome. N Engl J Med (2006) 8.64
Point: High-frequency ventilation is the optimal physiological approach to ventilate ARDS patients. J Appl Physiol (1985) (2007) 7.96
High-frequency oscillation in early acute respiratory distress syndrome. N Engl J Med (2013) 6.56
Early use of polymyxin B hemoperfusion in abdominal septic shock: the EUPHAS randomized controlled trial. JAMA (2009) 6.55
Identification of oxidative stress and Toll-like receptor 4 signaling as a key pathway of acute lung injury. Cell (2008) 6.37
Tidal hyperinflation during low tidal volume ventilation in acute respiratory distress syndrome. Am J Respir Crit Care Med (2006) 6.22
Driving pressure and survival in the acute respiratory distress syndrome. N Engl J Med (2015) 6.06
Ventilator-induced lung injury. N Engl J Med (2013) 5.40
Extracorporeal Co2 removal in hypercapnic patients at risk of noninvasive ventilation failure: a matched cohort study with historical control. Crit Care Med (2015) 5.22
Physiological effects of an open lung ventilatory strategy titrated on elastance-derived end-inspiratory transpulmonary pressure: study in a pig model*. Crit Care Med (2012) 4.71
An official American Thoracic Society workshop report: features and measurements of experimental acute lung injury in animals. Am J Respir Cell Mol Biol (2011) 4.65
Incidence and prognosis of intraabdominal hypertension in a mixed population of critically ill patients: a multiple-center epidemiological study. Crit Care Med (2005) 4.61
Design, conduct, analysis and reporting of a multi-national placebo-controlled trial of activated protein C for persistent septic shock. Intensive Care Med (2008) 4.21
Inhaled nitric oxide does not reduce mortality in patients with acute respiratory distress syndrome regardless of severity: systematic review and meta-analysis. Crit Care Med (2014) 4.11
Normothermic ex vivo lung perfusion in clinical lung transplantation. N Engl J Med (2011) 3.87
Mesenchymal stem cells reduce inflammation while enhancing bacterial clearance and improving survival in sepsis. Am J Respir Crit Care Med (2010) 3.83
Future research directions in acute lung injury: summary of a National Heart, Lung, and Blood Institute working group. Am J Respir Crit Care Med (2003) 3.75
Partial liquid ventilation in adult patients with acute respiratory distress syndrome. Am J Respir Crit Care Med (2005) 3.75
High tidal volume and positive fluid balance are associated with worse outcome in acute lung injury. Chest (2005) 3.58
What tidal volumes should be used in patients without acute lung injury? Anesthesiology (2007) 3.28
A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury. Nat Med (2005) 3.26
Predicting mortality risk in patients undergoing venovenous ECMO for ARDS due to influenza A (H1N1) pneumonia: the ECMOnet score. Intensive Care Med (2012) 3.24
Early vs late tracheotomy for prevention of pneumonia in mechanically ventilated adult ICU patients: a randomized controlled trial. JAMA (2010) 3.20
Continuous positive airway pressure for treatment of postoperative hypoxemia: a randomized controlled trial. JAMA (2005) 3.19
The Berlin definition of ARDS: an expanded rationale, justification, and supplementary material. Intensive Care Med (2012) 3.18
Critically ill patients with severe acute respiratory syndrome. JAMA (2003) 3.10
Angiotensin-converting enzyme 2 protects from severe acute lung failure. Nature (2005) 3.09
Incidence of acute lung injury in the United States. Crit Care Med (2003) 2.93
Tidal volume lower than 6 ml/kg enhances lung protection: role of extracorporeal carbon dioxide removal. Anesthesiology (2009) 2.91
Effect of a lung protective strategy for organ donors on eligibility and availability of lungs for transplantation: a randomized controlled trial. JAMA (2010) 2.77
Ventilator-induced lung injury: from the bench to the bedside. Intensive Care Med (2005) 2.75
Causes and timing of death in patients with ARDS. Chest (2005) 2.72
PAF-mediated pulmonary edema: a new role for acid sphingomyelinase and ceramide. Nat Med (2004) 2.66
Alveolar dynamics in acute lung injury: heterogeneous distension rather than cyclic opening and collapse. Crit Care Med (2009) 2.54
ECMO criteria for influenza A (H1N1)-associated ARDS: role of transpulmonary pressure. Intensive Care Med (2012) 2.50
Does dopamine administration in shock influence outcome? Results of the Sepsis Occurrence in Acutely Ill Patients (SOAP) Study. Crit Care Med (2006) 2.47
Pulmonary coagulopathy as a new target in therapeutic studies of acute lung injury or pneumonia--a review. Crit Care Med (2006) 2.45
Two-year outcomes, health care use, and costs of survivors of acute respiratory distress syndrome. Am J Respir Crit Care Med (2006) 2.39
Lung water assessment by lung ultrasonography in intensive care: a pilot study. Intensive Care Med (2012) 2.30
The Italian ECMO network experience during the 2009 influenza A(H1N1) pandemic: preparation for severe respiratory emergency outbreaks. Intensive Care Med (2011) 2.28
Chronic alcohol abuse is associated with an increased incidence of acute respiratory distress syndrome and severity of multiple organ dysfunction in patients with septic shock. Crit Care Med (2003) 2.27
Effects of recruiting maneuvers in patients with acute respiratory distress syndrome ventilated with protective ventilatory strategy. Anesthesiology (2002) 2.27
Continuous positive airway pressure for treatment of respiratory complications after abdominal surgery: a systematic review and meta-analysis. Ann Surg (2008) 2.26
Effect of acute lung injury and acute respiratory distress syndrome on outcome in critically ill trauma patients. Crit Care Med (2004) 2.20
Barriers to providing lung-protective ventilation to patients with acute lung injury. Crit Care Med (2004) 2.20
Alveolar recruitment in pulmonary and extrapulmonary acute respiratory distress syndrome: comparison using pressure-volume curve or static compliance. Anesthesiology (2007) 2.20
Hemodynamic monitoring in shock and implications for management. International Consensus Conference, Paris, France, 27-28 April 2006. Intensive Care Med (2007) 2.18
Sepsis and endothelial permeability. N Engl J Med (2010) 2.17
The application of esophageal pressure measurement in patients with respiratory failure. Am J Respir Crit Care Med (2014) 2.16
Effects of cyclic opening and closing at low- and high-volume ventilation on bronchoalveolar lavage cytokines. Crit Care Med (2004) 2.12
Mechanical ventilation alters the immune response in children without lung pathology. Intensive Care Med (2002) 2.11
Predictors of hospital mortality in a population-based cohort of patients with acute lung injury. Crit Care Med (2008) 2.09
Patient-ventilator interaction and sleep in mechanically ventilated patients: pressure support versus proportional assist ventilation. Crit Care Med (2007) 2.05
Ten big mistakes in intensive care medicine. Intensive Care Med (2014) 2.05
Broken barriers: a new take on sepsis pathogenesis. Sci Transl Med (2011) 2.01
An evaluation of systemic inflammatory response syndrome signs in the Sepsis Occurrence In Acutely Ill Patients (SOAP) study. Intensive Care Med (2006) 2.00
The rise of people power. Nature (2011) 1.99
Mechanical ventilation and acute renal failure. Crit Care Med (2005) 1.97
The association between body mass index and clinical outcomes in acute lung injury. Chest (2007) 1.96
Multicenter randomized comparison of the efficacy and safety of xenon and isoflurane in patients undergoing elective surgery. Anesthesiology (2003) 1.96
Hypercapnic acidosis and mortality in acute lung injury. Crit Care Med (2006) 1.93
Injurious ventilation induces widespread pulmonary epithelial expression of tumor necrosis factor-alpha and interleukin-6 messenger RNA. Crit Care Med (2002) 1.93
Efficacy of ventilator waveforms observation in detecting patient-ventilator asynchrony. Crit Care Med (2011) 1.89
Epidemiology of mechanical ventilation: analysis of the SAPS 3 database. Intensive Care Med (2009) 1.88
Combining high-frequency oscillatory ventilation and recruitment maneuvers in adults with early acute respiratory distress syndrome: the Treatment with Oscillation and an Open Lung Strategy (TOOLS) Trial pilot study. Crit Care Med (2005) 1.81
Effectiveness of polymyxin B-immobilized fiber column in sepsis: a systematic review. Crit Care (2007) 1.80
Intensive care unit-acquired neuromyopathy and corticosteroids in survivors of persistent ARDS. Intensive Care Med (2008) 1.76
Mechanical ventilation modulates Toll-like receptor signaling pathway in a sepsis-induced lung injury model. Intensive Care Med (2010) 1.76
Diagnosis of ventilator-associated pneumonia: a systematic review of the literature. Crit Care (2008) 1.76
Subject-ventilator synchrony during neural versus pneumatically triggered non-invasive helmet ventilation. Intensive Care Med (2008) 1.74
Functional repair of human donor lungs by IL-10 gene therapy. Sci Transl Med (2009) 1.72
Influence of neurally adjusted ventilatory assist and positive end-expiratory pressure on breathing pattern in rabbits with acute lung injury. Crit Care Med (2006) 1.71
Age-, sex-, and race-based differences among patients enrolled versus not enrolled in acute lung injury clinical trials. Crit Care Med (2010) 1.71
Modulation of bacterial growth by tumor necrosis factor-alpha in vitro and in vivo. Am J Respir Crit Care Med (2003) 1.70
Early CPAP prevents evolution of acute lung injury in patients with hematologic malignancy. Intensive Care Med (2010) 1.69
A study of the physiologic responses to a lung recruitment maneuver in acute lung injury and acute respiratory distress syndrome. Respir Care (2008) 1.65
Effect of mechanical ventilation on cytokine response to intratracheal lipopolysaccharide. Anesthesiology (2004) 1.64
Mechanical stress induces lung fibrosis by epithelial-mesenchymal transition. Crit Care Med (2012) 1.63
Circadian rhythms: from basic mechanisms to the intensive care unit. Crit Care Med (2012) 1.63
Overview of ventilator-induced lung injury mechanisms. Curr Opin Crit Care (2005) 1.59
Diurnal sedative changes during intensive care: impact on liberation from mechanical ventilation and delirium. Crit Care Med (2012) 1.59
Pulmonary atelectasis during low stretch ventilation: "open lung" versus "lung rest" strategy. Crit Care Med (2009) 1.58
Effect of intensive care unit organizational model and structure on outcomes in patients with acute lung injury. Am J Respir Crit Care Med (2007) 1.58