Published in Science on May 10, 2002
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Caloric restriction: powerful protection for the aging heart and vasculature. Am J Physiol Heart Circ Physiol (2011) 1.35
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Life expectancy and disparity: an international comparison of life table data. BMJ Open (2011) 1.27
Identifying the genomic determinants of aging and longevity in human population studies: progress and challenges. Bioessays (2013) 1.26
Nonagenarians and centenarians in Switzerland, 1860-2001: a demographic analysis. J Epidemiol Community Health (2005) 1.24
Bayesian Population Projections for the United Nations. Stat Sci (2014) 1.20
Variations in apolipoprotein E frequency with age in a pooled analysis of a large group of older people. Am J Epidemiol (2011) 1.19
Age, cohort and period effects on hip fracture incidence: analysis and predictions from New Zealand data 1974-2007. Osteoporos Int (2010) 1.19
Predicting successful aging in a population-based sample of georgia centenarians. Curr Gerontol Geriatr Res (2010) 1.18
The Janus face of DNA methylation in aging. Aging (Albany NY) (2010) 1.17
Colloquium paper: how grandmother effects plus individual variation in frailty shape fertility and mortality: guidance from human-chimpanzee comparisons. Proc Natl Acad Sci U S A (2010) 1.17
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Human insulin/IGF-1 and familial longevity at middle age. Aging (Albany NY) (2009) 1.16
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Palliative care delivery across health sectors: A population-level observational study. Palliat Med (2016) 1.15
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Lipid metabolism in long-lived families: the Leiden Longevity Study. Age (Dordr) (2010) 1.14
Grandmothering and natural selection. Proc Biol Sci (2010) 1.13
Genetics and genomics of human ageing. Philos Trans R Soc Lond B Biol Sci (2011) 1.13
An unsuitable and degraded diet? Part three: Victorian consumption patterns and their health benefits. J R Soc Med (2008) 1.11
Why human lifespan is rapidly increasing: solving "longevity riddle" with "revealed-slow-aging" hypothesis. Aging (Albany NY) (2010) 1.11
Potential gains in reproductive-aged life expectancy by eliminating maternal mortality: a demographic bonus of achieving MDG 5. PLoS One (2014) 1.10
Aging. It's never too late. Science (2003) 1.10
The epidemiology of longevity and exceptional survival. Epidemiol Rev (2013) 1.09
Normal brain ageing: models and mechanisms. Philos Trans R Soc Lond B Biol Sci (2005) 1.04
Age-specific trends in morbidity, mortality and case-fatality from cardiovascular disease, myocardial infarction and stroke in advanced age: evaluation in the Swedish population. PLoS One (2013) 1.03
Life-long spontaneous exercise does not prolong lifespan but improves health span in mice. Longev Healthspan (2013) 1.02
Do women stop early? Similarities in fertility decline in humans and chimpanzees. Ann N Y Acad Sci (2010) 0.98
Traffic-related air pollution in relation to cognitive function in older adults. Epidemiology (2014) 0.97
Advanced glycation end products, diabetes and ageing. Z Gerontol Geriatr (2007) 0.97
Trends in senescent life expectancy. Popul Stud (Camb) (2009) 0.96
Population screening for colorectal cancer: the implications of an ageing population. Br J Cancer (2008) 0.96
Growth hormone, inflammation and aging. Pathobiol Aging Age Relat Dis (2012) 0.96
Calorie restriction: what recent results suggest for the future of ageing research. Eur J Clin Invest (2010) 0.95
Three measures of longevity: time trends and record values. Demography (2010) 0.95
Self-regulation of common age-related challenges: benefits for older adults' psychological and physical health. J Behav Med (2006) 0.94
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Sex differential in mortality trends of old-aged Danes: a nation wide study of age, period and cohort effects. Eur J Epidemiol (2008) 0.94
Global divergence in critical income for adult and childhood survival: analyses of mortality using Michaelis-Menten. Elife (2012) 0.94
The new science of ageing. Philos Trans R Soc Lond B Biol Sci (2011) 0.94
Apolipoprotein D takes center stage in the stress response of the aging and degenerative brain. Neurobiol Aging (2014) 0.93
Meta-analysis on blood transcriptomic studies identifies consistently coexpressed protein-protein interaction modules as robust markers of human aging. Aging Cell (2013) 0.93
The effect of cognitive impairment on the predictive value of multimorbidity for the increase in disability in the oldest old: the Leiden 85-plus Study. Age Ageing (2011) 0.93
Predictors of longevity: evidence from the oldest old in China. Am J Public Health (2008) 0.92
Birth cohort differences in the prevalence of longevity-associated variants in APOE and FOXO3A in Danish long-lived individuals. Exp Gerontol (2014) 0.91
Trends and variation in mild disability and functional limitations among older adults in Norway, 1986-2008. Eur J Ageing (2011) 0.91
Biodemographic analysis of male honey bee mortality. Aging Cell (2005) 0.91
Psychosocial Factors Associated with Longevity in the United States: Age Differences between the Old and Oldest-Old in the Health and Retirement Study. J Aging Res (2011) 0.91
Hospitalisations for fracture and associated costs between 2000 and 2009 in Ireland: a trend analysis. Osteoporos Int (2012) 0.90
Visualizing Europe's demographic scars with coplots and contour plots. Int J Epidemiol (2013) 0.90
The Cost of Uncertain Life Span. J Popul Econ (2008) 0.90
Scientific evidence and rationale for the development of curcumin and resveratrol as nutraceutricals for joint health. Int J Mol Sci (2012) 0.90
China's New Demographic Reality: Learning from the 2010 Census. Popul Dev Rev (2013) 0.90
Ageing populations: the challenges ahead. Lancet (2009) 13.42
The quest for genetic determinants of human longevity: challenges and insights. Nat Rev Genet (2006) 3.93
A stress-sensitive reporter predicts longevity in isogenic populations of Caenorhabditis elegans. Nat Genet (2005) 3.29
Physical and cognitive functioning of people older than 90 years: a comparison of two Danish cohorts born 10 years apart. Lancet (2013) 3.29
Genetic influence on human lifespan and longevity. Hum Genet (2006) 3.27
Telomere length and mortality: a study of leukocytes in elderly Danish twins. Am J Epidemiol (2008) 2.85
Predictors of mortality in 2,249 nonagenarians--the Danish 1905-Cohort Survey. J Am Geriatr Soc (2003) 2.79
The Danish Twin Registry: 127 birth cohorts of twins. Twin Res (2002) 2.53
No association between telomere length and survival among the elderly and oldest old. Epidemiology (2006) 2.33
Men: good health and high mortality. Sex differences in health and aging. Aging Clin Exp Res (2008) 2.33
Exceptional longevity does not result in excessive levels of disability. Proc Natl Acad Sci U S A (2008) 2.19
Age trajectories of grip strength: cross-sectional and longitudinal data among 8,342 Danes aged 46 to 102. Ann Epidemiol (2006) 1.97
Longevity studies in GenomEUtwin. Twin Res (2003) 1.66
A meta-analysis of four genome-wide association studies of survival to age 90 years or older: the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium. J Gerontol A Biol Sci Med Sci (2010) 1.65
The co-occurrence of mtDNA mutations on different oxidative phosphorylation subunits, not detected by haplogroup analysis, affects human longevity and is population specific. Aging Cell (2013) 1.56
Hand grip strength: a phenotype suitable for identifying genetic variants affecting mid- and late-life physical functioning. Genet Epidemiol (2002) 1.46
Improving activities of daily living in danish centenarians--but only in women: a comparative study of two birth cohorts born in 1895 and 1905. J Gerontol A Biol Sci Med Sci (2008) 1.40
Perceived age as clinically useful biomarker of ageing: cohort study. BMJ (2009) 1.40
Effects of FOXO genotypes on longevity: a biodemographic analysis. J Gerontol A Biol Sci Med Sci (2010) 1.38
The heritability of telomere length among the elderly and oldest-old. Twin Res Hum Genet (2005) 1.35
Genome-wide linkage analysis for human longevity: Genetics of Healthy Aging Study. Aging Cell (2013) 1.33
Reproductive improvement and senescence in a long-lived bird. Proc Natl Acad Sci U S A (2010) 1.31
Why Danes are smug: comparative study of life satisfaction in the European Union. BMJ (2006) 1.28
Age trajectories of genetic variance in physical functioning: a longitudinal study of Danish twins aged 70 years and older. Behav Genet (2003) 1.27
Centenarians--a useful model for healthy aging? A 29-year follow-up of hospitalizations among 40,000 Danes born in 1905. Aging Cell (2009) 1.27
Why some women look young for their age. PLoS One (2009) 1.24
Genetics of healthy aging in Europe: the EU-integrated project GEHA (GEnetics of Healthy Aging). Ann N Y Acad Sci (2007) 1.21
Increased effect of the ApoE gene on survival at advanced age in healthy and long-lived Danes: two nationwide cohort studies. Aging Cell (2010) 1.20
"Looking old for your age": genetics and mortality. Epidemiology (2004) 1.19
Human mortality improvement in evolutionary context. Proc Natl Acad Sci U S A (2012) 1.15
The Danish Twin Registry in the new millennium. Twin Res Hum Genet (2006) 1.15
Genetic contribution to rate of change in functional abilities among Danish twins aged 75 years or more. Am J Epidemiol (2002) 1.15
Losses of expected lifetime in the United States and other developed countries: methods and empirical analyses. Demography (2011) 1.14
Evolution. Getting to the root of aging. Science (2012) 1.13
Family clustering in Sardinian longevity: a genealogical approach. Exp Gerontol (2006) 1.10
Cross-national comparison of sex differences in health and mortality in Denmark, Japan and the US. Eur J Epidemiol (2010) 1.10
Human longevity and variation in GH/IGF-1/insulin signaling, DNA damage signaling and repair and pro/antioxidant pathway genes: cross sectional and longitudinal studies. Exp Gerontol (2012) 1.10
The male-female health-survival paradox: a survey and register study of the impact of sex-specific selection and information bias. Ann Epidemiol (2009) 1.09
Loss of partner and suicide risks among oldest old: a population-based register study. Age Ageing (2004) 1.09
Evidence from case-control and longitudinal studies supports associations of genetic variation in APOE, CETP, and IL6 with human longevity. Age (Dordr) (2012) 1.09
Major genetic susceptibility for venous thromboembolism in men: a study of Danish twins. Epidemiology (2003) 1.07
The Danish Twin Registry: linking surveys, national registers, and biological information. Twin Res Hum Genet (2012) 1.05
Tooth cementum annulation for age estimation: results from a large known-age validation study. Am J Phys Anthropol (2004) 1.05
Cognitive impairment and mortality among nonagenarians: the Danish 1905 cohort survey. Dement Geriatr Cogn Disord (2002) 0.99
Advances in measuring lifespan in the yeast Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (2004) 0.96
Comment on "Inflammatory exposure and historical changes in human life-spans". Science (2005) 0.95
Do children of long-lived parents age more successfully? Epidemiology (2002) 0.95
Sex differential in mortality trends of old-aged Danes: a nation wide study of age, period and cohort effects. Eur J Epidemiol (2008) 0.94
Biological mechanisms of disease and death in Moscow: rationale and design of the survey on Stress Aging and Health in Russia (SAHR). BMC Public Health (2009) 0.94
A centenarian-only approach for assessing gene-gene interaction in human longevity. Eur J Hum Genet (2002) 0.92
Hair loss among elderly men: etiology and impact on perceived age. J Gerontol A Biol Sci Med Sci (2005) 0.91
Sex differences in the level and rate of change of physical function and grip strength in the Danish 1905-cohort study. J Aging Health (2010) 0.90
Angiotensin I-converting enzyme (ACE) gene polymorphism in relation to physical performance, cognition and survival--a follow-up study of elderly Danish twins. Ann Epidemiol (2003) 0.89
Survival differences among native-born and foreign-born older adults in the United States. PLoS One (2012) 0.88
Changes in hospitalisation and surgical procedures among the oldest-old: a follow-up study of the entire Danish 1895 and 1905 cohorts from ages 85 to 99 years. Age Ageing (2013) 0.88
The heritability of cause-specific mortality: a correlated gamma-frailty model applied to mortality due to respiratory diseases in Danish twins born 1870-1930. Stat Med (2003) 0.88
A novel sampling design to explore gene-longevity associations: the ECHA study. Eur J Hum Genet (2007) 0.86
An allele of HRAS1 3'variable number of tandem repeats is a frailty allele: implication for an evolutionarily-conserved pathway involved in longevity. Gene (2002) 0.85
Prevalence, components, and correlates of metabolic syndrome (MetS) among elderly Muscovites. Arch Gerontol Geriatr (2011) 0.85
Cancer and longevity--is there a trade-off? A study of cooccurrence in Danish twin pairs born 1900-1918. J Gerontol A Biol Sci Med Sci (2012) 0.85
Biodemographic trajectories of age-specific reproliferation from stationary phase in the yeast Saccharomyces cerevisiae seem multiphasic. Mech Ageing Dev (2003) 0.84
Steep increase in best-practice cohort life expectancy. Popul Dev Rev (2011) 0.83
Physical and mental decline and yet rather happy? A study of Danes aged 45 and older. Aging Ment Health (2014) 0.83
The correlation of fecundability among twins: evidence of a genetic effect on fertility? Epidemiology (2003) 0.82
Symmetrically dividing cells of the fission yeast schizosaccharomyces pombe do age. Biogerontology (2006) 0.82
Reproduction life history and hip fractures. Ann Epidemiol (2002) 0.82
Plasticity of death rates in stationary phase in Saccharomyces cerevisiae. Aging Cell (2008) 0.82
Estimating haplotype relative risks on human survival in population-based association studies. Hum Hered (2005) 0.81
Skewed X inactivation and survival: a 13-year follow-up study of elderly twins and singletons. Eur J Hum Genet (2011) 0.81
Perceived stress and biological risk: is the link stronger in Russians than in Taiwanese and Americans? Stress (2013) 0.79
Optimism and survival: does an optimistic outlook predict better survival at advanced ages? A twelve-year follow-up of Danish nonagenarians. Aging Clin Exp Res (2013) 0.79
Sex Differences in Medication and Primary Healthcare Use before and after Spousal Bereavement at Older Ages in Denmark: Nationwide Register Study of over 6000 Bereavements. J Aging Res (2011) 0.78
A case-only approach for assessing gene by sex interaction in human longevity. J Gerontol A Biol Sci Med Sci (2002) 0.78
Twins with implanted pacemakers: Is there an increased mortality risk for the co-twin? A follow-up study based on the Danish Twin Registry and the Danish Pacemaker Register. Europace (2005) 0.78
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James Vaupel: an innovator in the demography of ageing. Interview by Samuel Loewenberg. Lancet (2009) 0.75
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Stem cell divisions per se do not cause cancer. Epidemiology (2016) 0.75