PubRank

Tariq M Rana

Author PubWeight™ 97.79‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Translation repression in human cells by microRNA-induced gene silencing requires RCK/p54. PLoS Biol 2006 6.41
2 siRNA function in RNAi: a chemical modification analysis. RNA 2003 4.93
3 RNAi in human cells: basic structural and functional features of small interfering RNA. Mol Cell 2002 3.81
4 Specific and potent RNAi in the nucleus of human cells. Nat Struct Mol Biol 2005 3.16
5 Cellular microRNA and P bodies modulate host-HIV-1 interactions. Mol Cell 2009 3.05
6 Small RNA-mediated regulation of iPS cell generation. EMBO J 2011 2.95
7 Small-molecule inhibition of HIV-1 Vif. Nat Biotechnol 2008 2.83
8 RNA helicase A interacts with RISC in human cells and functions in RISC loading. Mol Cell 2007 2.72
9 Human retroviral host restriction factors APOBEC3G and APOBEC3F localize to mRNA processing bodies. PLoS Pathog 2006 2.61
10 Visualizing a correlation between siRNA localization, cellular uptake, and RNAi in living cells. Chem Biol 2004 2.05
11 Small RNAs: regulators and guardians of the genome. J Cell Physiol 2007 1.86
12 Target accessibility dictates the potency of human RISC. Nat Struct Mol Biol 2005 1.78
13 The long noncoding RNA THRIL regulates TNFα expression through its interaction with hnRNPL. Proc Natl Acad Sci U S A 2013 1.78
14 The frameshift signal of HIV-1 involves a potential intramolecular triplex RNA structure. Proc Natl Acad Sci U S A 2002 1.46
15 TAR RNA loop: a scaffold for the assembly of a regulatory switch in HIV replication. Proc Natl Acad Sci U S A 2002 1.44
16 HIV-1 protease inhibitors from inverse design in the substrate envelope exhibit subnanomolar binding to drug-resistant variants. J Am Chem Soc 2008 1.43
17 Tat stimulates cotranscriptional capping of HIV mRNA. Mol Cell 2002 1.43
18 Analysis of HIV-1 viral infectivity factor-mediated proteasome-dependent depletion of APOBEC3G: correlating function and subcellular localization. J Biol Chem 2004 1.42
19 Evaluating the substrate-envelope hypothesis: structural analysis of novel HIV-1 protease inhibitors designed to be robust against drug resistance. J Virol 2010 1.39
20 MicroRNAs encoded by Kaposi's sarcoma-associated herpesvirus regulate viral life cycle. EMBO Rep 2010 1.34
21 Potent RNAi by short RNA triggers. RNA 2008 1.29
22 Deep annotation of mouse iso-miR and iso-moR variation. Nucleic Acids Res 2012 1.27
23 Inhibition of human immunodeficiency virus type 1 replication by RNA interference directed against human transcription elongation factor P-TEFb (CDK9/CyclinT1). J Virol 2004 1.26
24 Specific HIV-1 TAR RNA loop sequence and functional groups are required for human cyclin T1-Tat-TAR ternary complex formation. Biochemistry 2002 1.21
25 microRNAs modulate iPS cell generation. RNA 2011 1.19
26 Discovery of HIV-1 protease inhibitors with picomolar affinities incorporating N-aryl-oxazolidinone-5-carboxamides as novel P2 ligands. J Med Chem 2006 1.17
27 Design and creation of new nanomaterials for therapeutic RNAi. ACS Chem Biol 2007 1.16
28 A kinase inhibitor screen identifies small-molecule enhancers of reprogramming and iPS cell generation. Nat Commun 2012 1.14
29 Design of mutation-resistant HIV protease inhibitors with the substrate envelope hypothesis. Chem Biol Drug Des 2007 1.12
30 Discovery of a small molecule Tat-trans-activation-responsive RNA antagonist that potently inhibits human immunodeficiency virus-1 replication. J Biol Chem 2003 1.11
31 Discovery of nonsteroidal anti-inflammatory drug and anticancer drug enhancing reprogramming and induced pluripotent stem cell generation. Stem Cells 2011 1.08
32 Dissecting RNA-interference pathway with small molecules. Chem Biol 2005 1.07
33 Modulating HIV-1 replication by RNA interference directed against human transcription elongation factor SPT5. Retrovirology 2004 1.05
34 LIM-domain proteins, LIMD1, Ajuba, and WTIP are required for microRNA-mediated gene silencing. Proc Natl Acad Sci U S A 2010 1.03
35 Silencing microRNA by interfering nanoparticles in mice. Nucleic Acids Res 2011 1.02
36 Evolutionary emergence of microRNAs in human embryonic stem cells. PLoS One 2008 0.98
37 Design and synthesis of HIV-1 protease inhibitors incorporating oxazolidinones as P2/P2' ligands in pseudosymmetric dipeptide isosteres. J Med Chem 2007 0.97
38 Selective binding of TAR RNA by a Tat-derived beta-peptide. Org Lett 2003 0.96
39 Therapeutic gene silencing delivered by a chemically modified small interfering RNA against mutant SOD1 slows amyotrophic lateral sclerosis progression. J Biol Chem 2008 0.96
40 Identification of flavopiridol analogues that selectively inhibit positive transcription elongation factor (P-TEFb) and block HIV-1 replication. Chembiochem 2009 0.95
41 Additivity in the analysis and design of HIV protease inhibitors. J Med Chem 2009 0.95
42 Structure-based design, synthesis, and structure-activity relationship studies of HIV-1 protease inhibitors incorporating phenyloxazolidinones. J Med Chem 2010 0.93
43 Gene regulation by non-coding RNAs. Crit Rev Biochem Mol Biol 2013 0.92
44 RNA-based mechanisms regulating host-virus interactions. Immunol Rev 2013 0.92
45 Synthesis and structure-activity relationship studies of HIV-1 virion infectivity factor (Vif) inhibitors that block viral replication. ChemMedChem 2012 0.87
46 P-TEFb kinase complex phosphorylates histone H1 to regulate expression of cellular and HIV-1 genes. J Biol Chem 2010 0.87
47 U30 of 7SK RNA forms a specific photo-cross-link with Hexim1 in the context of both a minimal RNA-binding site and a fully reconstituted 7SK/Hexim1/P-TEFb ribonucleoprotein complex. J Mol Biol 2009 0.86
48 Molecular mechanisms of RNA-triggered gene silencing machineries. Acc Chem Res 2012 0.86
49 Nanotubes functionalized with lipids and natural amino acid dendrimers: a new strategy to create nanomaterials for delivering systemic RNAi. Bioconjug Chem 2010 0.85
50 Delivery of therapeutic RNAi by nanovehicles. Chembiochem 2009 0.85
51 Substrate envelope-designed potent HIV-1 protease inhibitors to avoid drug resistance. Chem Biol 2013 0.84
52 Learning the molecular mechanisms of the reprogramming factors: let's start from microRNAs. Mol Biosyst 2012 0.84
53 miR-TRAP: a benchtop chemical biology strategy to identify microRNA targets. Angew Chem Int Ed Engl 2012 0.84
54 Inhibition of HIV tat-TAR interactions by an antisense oligo-2'-O-methylribonucleoside methylphosphonate. Bioorg Med Chem Lett 2003 0.84
55 Core small nuclear ribonucleoprotein particle splicing factor SmD1 modulates RNA interference in Drosophila. Proc Natl Acad Sci U S A 2013 0.84
56 Decoding the noncoding: prospective of lncRNA-mediated innate immune regulation. RNA Biol 2014 0.82
57 Staged miRNA re-regulation patterns during reprogramming. Genome Biol 2013 0.82
58 A bimolecular mechanism of HIV-1 Tat protein interaction with RNA polymerase II transcription elongation complexes. J Mol Biol 2002 0.82
59 Efficient Computation of Small-Molecule Configurational Binding Entropy and Free Energy Changes by Ensemble Enumeration. J Chem Theory Comput 2013 0.82
60 Testing the substrate-envelope hypothesis with designed pairs of compounds. ACS Chem Biol 2013 0.81
61 Using microRNAs to enhance the generation of induced pluripotent stem cells. Curr Protoc Stem Cell Biol 2012 0.81
62 Interfering nanoparticles for silencing microRNAs. Methods Enzymol 2012 0.81
63 Orientation and affinity of HIV-1 Tat fragments in Tat-TAR complex determined by fluorescence resonance energy transfer. Bioconjug Chem 2006 0.81
64 Mechanism of site-specific psoralen photoadducts formation in triplex DNA directed by psoralen-conjugated oligonucleotides. Biochemistry 2005 0.81
65 Dynamics of nascent mRNA folding and RNA-protein interactions: an alternative TAR RNA structure is involved in the control of HIV-1 mRNA transcription. Nucleic Acids Res 2006 0.81
66 A new class of RNA-binding oligomers: peptoid amide and ester analogues. Bioconjug Chem 2002 0.79
67 Design, synthesis, and biological and structural evaluations of novel HIV-1 protease inhibitors to combat drug resistance. J Med Chem 2012 0.79
68 Design, microwave-assisted synthesis, and photophysical properties of small molecule organic antennas for luminescence resonance energy transfer. J Comb Chem 2005 0.78
69 Design and synthesis of a novel peptidomimetic inhibitor of HIV-1 Tat-TAR interactions: squaryldiamide as a new potential bioisostere of unsubstituted guanidine. Bioorg Med Chem Lett 2005 0.78
70 Microwave-assisted parallel synthesis of a 4,6-diamino-2,2-dimethyl-1,2-dihydro-1-phenyl-s-triazine library. J Comb Chem 2004 0.77
71 Phosphorylation of histone H1 by P-TEFb is a necessary step in skeletal muscle differentiation. J Cell Physiol 2012 0.77
72 In Vivo Delivery of RNAi by Reducible Interfering Nanoparticles (iNOPs). ACS Med Chem Lett 2013 0.77
73 Quantitative analysis of RNA-mediated protein-protein interactions in living cells by FRET. Chem Biol Drug Des 2007 0.75
74 Design and assembly of new nonviral RNAi delivery agents by microwave-assisted quaternization (MAQ) of tertiary amines. Bioconjug Chem 2010 0.75
75 Solid-phase synthesis of alpha-(2-(benzylthio)-1,4-dihydro-6-methyl-4-p-tolylpyrimidine-5-carboxamido) acids: a new strategy to create diversity in heterocyclic scaffolds. J Comb Chem 2004 0.75
76 Strategies to antagonize miRNA functions in vitro and in vivo. Nanomedicine (Lond) 2014 0.75