Published in Immunology on May 20, 2008
Expansion and activation kinetics of immune cells during early phase of GVHD in mouse model based on chemotherapy conditioning. Clin Dev Immunol (2010) 0.80
Advances in targeting co-inhibitory and co-stimulatory pathways in transplantation settings: the Yin to the Yang of cancer immunotherapy. Immunol Rev (2017) 0.78
Allogeneic splenocyte transfer and lipopolysaccharide inhalations induce differential T cell expansion and lung injury: a novel model of pulmonary graft-versus-host disease. PLoS One (2014) 0.75
Allogeneic unrelated bone marrow transplantation from older donors results in worse prognosis in recipients with aplastic anemia. Haematologica (2016) 0.75
Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus. BMC Dev Biol (2001) 31.56
Regulatory T cell lineage specification by the forkhead transcription factor foxp3. Immunity (2005) 23.00
Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8+ T cells. J Exp Med (2005) 8.13
Induction of tumor immunity by removing CD25+CD4+ T cells: a common basis between tumor immunity and autoimmunity. J Immunol (1999) 7.60
Regulatory T cells in the control of immune pathology. Nat Immunol (2001) 6.98
A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells. J Exp Med (1996) 6.73
Donor-type CD4(+)CD25(+) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation. J Exp Med (2002) 6.11
Transgenic mice with hematopoietic and lymphoid specific expression of Cre. Eur J Immunol (2003) 5.73
A very high level of crossreactivity is an essential feature of the T-cell receptor. Immunol Today (1998) 5.07
Constitutive cytokine mRNAs mark natural killer (NK) and NK T cells poised for rapid effector function. J Exp Med (2003) 4.68
Conditional deletion of Gata3 shows its essential function in T(H)1-T(H)2 responses. Nat Immunol (2004) 4.41
In vivo analyses of early events in acute graft-versus-host disease reveal sequential infiltration of T-cell subsets. Blood (2005) 3.13
OX40 promotes Bcl-xL and Bcl-2 expression and is essential for long-term survival of CD4 T cells. Immunity (2001) 3.08
Only the CD62L+ subpopulation of CD4+CD25+ regulatory T cells protects from lethal acute GVHD. Blood (2004) 2.95
L-Selectin(hi) but not the L-selectin(lo) CD4+25+ T-regulatory cells are potent inhibitors of GVHD and BM graft rejection. Blood (2004) 2.90
Ox-40 ligand: a potent costimulatory molecule for sustaining primary CD4 T cell responses. J Immunol (1998) 2.74
Tyrosine kinase receptor RET is a key regulator of Peyer's patch organogenesis. Nature (2007) 2.65
Memory CD4+ T cells do not induce graft-versus-host disease. J Clin Invest (2003) 2.54
OX40 costimulation turns off Foxp3+ Tregs. Blood (2007) 2.52
CD4 T cell cytokine differentiation: the B cell activation molecule, OX40 ligand, instructs CD4 T cells to express interleukin 4 and upregulates expression of the chemokine receptor, Blr-1. J Exp Med (1998) 2.45
Cytokine dysregulation and acute graft-versus-host disease. Blood (1992) 2.43
Triggering of OX40 (CD134) on CD4(+)CD25+ T cells blocks their inhibitory activity: a novel regulatory role for OX40 and its comparison with GITR. Blood (2004) 2.38
Transfer of allogeneic CD62L- memory T cells without graft-versus-host disease. Blood (2003) 2.31
Thymic-independent T cell regeneration occurs via antigen-driven expansion of peripheral T cells resulting in a repertoire that is limited in diversity and prone to skewing. J Immunol (1996) 2.24
T cell regulation as a side effect of homeostasis and competition. J Exp Med (2003) 2.15
The OX40 costimulatory receptor determines the development of CD4 memory by regulating primary clonal expansion. J Immunol (2000) 2.04
Depletion of CD25+ regulatory cells uncovers immune responses to shared murine tumor rejection antigens. Eur J Immunol (2002) 1.88
Graft-versus-leukemia reactions in allogeneic chimeras. Blood (2003) 1.84
Cutting edge: OX40 inhibits TGF-beta- and antigen-driven conversion of naive CD4 T cells into CD25+Foxp3+ T cells. J Immunol (2007) 1.82
Robust B cell immunity but impaired T cell proliferation in the absence of CD134 (OX40). J Immunol (1999) 1.58
Effector memory CD4+ T cells mediate graft-versus-leukemia without inducing graft-versus-host disease. Blood (2007) 1.54
Inability of memory T cells to induce graft-versus-host disease is a result of an abortive alloresponse. Blood (2007) 1.49
Prevention of acute graft-versus-host disease by blocking T-cell entry to secondary lymphoid organs. Blood (2007) 1.48
Kinetics of Th1 and Th2 cytokine production during the early course of acute and chronic murine graft-versus-host disease. Regulatory role of donor CD8+ T cells. J Immunol (1995) 1.46
Danger and OX40 receptor signaling synergize to enhance memory T cell survival by inhibiting peripheral deletion. J Immunol (2000) 1.45
Nitric oxide induces CD4+CD25+ Foxp3 regulatory T cells from CD4+CD25 T cells via p53, IL-2, and OX40. Proc Natl Acad Sci U S A (2007) 1.45
OX-40: life beyond the effector T cell stage. Semin Immunol (1998) 1.43
A critical role for OX40 in T cell-mediated immunopathology during lung viral infection. J Exp Med (2003) 1.35
Modulation of dendritic cell function by naive and regulatory CD4+ T cells. J Immunol (2006) 1.31
Recent advances in graft-versus-host disease (GVHD) prevention. Immunol Rev (1997) 1.24
Role of OX40 signals in coordinating CD4 T cell selection, migration, and cytokine differentiation in T helper (Th)1 and Th2 cells. J Exp Med (2000) 1.22
A major role for memory CD4 T cells in the control of lymphopenia-induced proliferation of naive CD4 T cells. J Immunol (2005) 1.17
Alloreactive memory T cells are responsible for the persistence of graft-versus-host disease. J Immunol (2005) 1.17
Naive and memory T cells induce different types of graft-versus-host disease. J Immunol (2007) 1.12
Blockade of CD134 (OX40)-CD134L interaction ameliorates lethal acute graft-versus-host disease in a murine model of allogeneic bone marrow transplantation. Blood (2000) 1.12
Minor H antigens: genes and peptides. Transpl Immunol (2002) 1.09
CD40 and OX40 ligand are increased on stimulated asthmatic airway smooth muscle. J Allergy Clin Immunol (2005) 1.08
Ligation of OX40 (CD134) regulates graft-versus-host disease (GVHD) and graft rejection in allogeneic bone marrow transplant recipients. Blood (2003) 1.03
Progression from acute to chronic disease in a murine parent-into-F1 model of graft-versus-host disease. J Immunol (2000) 1.03
CD4+CD25+ regulatory T lymphocytes in bone marrow transplantation. Semin Immunol (2006) 1.02
OX40 (CD134) blockade inhibits the co-stimulatory cascade and promotes heart allograft survival. Transplantation (2004) 0.88
Blockade of the OX40 ligand prolongs corneal allograft survival. Eur J Immunol (2007) 0.84
CD4+CD25+ regulatory T cells in hematopoietic stem cell transplantation. Curr Top Microbiol Immunol (2005) 0.84
Immunotherapy in allogeneic hematopoietic stem cell transplantation--not just a case for effector cells. Bone Marrow Transplant (2005) 0.81
Donor lymphocyte infusions. Curr Opin Hematol (1999) 0.79
Lymphopenia-induced proliferation of donor T cells reduces their capacity for causing acute graft-versus-host disease. Exp Hematol (2007) 0.79
TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity (2006) 29.29
The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins. Nature (2008) 10.15
Transforming growth factor-beta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset. Nat Immunol (2008) 6.76
Interleukin-17-producing gammadelta T cells selectively expand in response to pathogen products and environmental signals. Immunity (2009) 6.05
Fate mapping of IL-17-producing T cells in inflammatory responses. Nat Immunol (2011) 5.98
Transgenic mice with hematopoietic and lymphoid specific expression of Cre. Eur J Immunol (2003) 5.73
Highly purified Th17 cells from BDC2.5NOD mice convert into Th1-like cells in NOD/SCID recipient mice. J Clin Invest (2009) 4.74
Signals mediated by transforming growth factor-beta initiate autoimmune encephalomyelitis, but chronic inflammation is needed to sustain disease. Nat Immunol (2006) 4.44
Natural agonists for aryl hydrocarbon receptor in culture medium are essential for optimal differentiation of Th17 T cells. J Exp Med (2008) 3.50
IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells. J Immunol (2004) 3.46
The basic leucine zipper transcription factor E4BP4 is essential for natural killer cell development. Nat Immunol (2009) 3.27
Effector T cell plasticity: flexibility in the face of changing circumstances. Nat Immunol (2010) 3.12
An IL-9 fate reporter demonstrates the induction of an innate IL-9 response in lung inflammation. Nat Immunol (2011) 2.69
Impairment of immunological memory in the absence of MHC despite survival of memory T cells. Nat Immunol (2002) 2.42
Plasticity of Th17 cells in Peyer's patches is responsible for the induction of T cell-dependent IgA responses. Nat Immunol (2013) 2.24
The aryl hydrocarbon receptor in immunity. Trends Immunol (2009) 2.19
T cell regulation as a side effect of homeostasis and competition. J Exp Med (2003) 2.15
IL-9-mediated survival of type 2 innate lymphoid cells promotes damage control in helminth-induced lung inflammation. J Exp Med (2013) 1.75
The functional plasticity of T cell subsets. Nat Rev Immunol (2009) 1.74
Involvement of avidity for major histocompatibility complex in homeostasis of naive and memory T cells. J Exp Med (2003) 1.71
The resolution of inflammation. Nat Rev Immunol (2012) 1.58
Determining disease intervention strategies using spatially resolved simulations. PLoS One (2013) 1.49
TGFbeta1, a "Jack of all trades": the link with pro-inflammatory IL-17-producing T cells. Trends Immunol (2006) 1.46
CD25+ CD4+ T cells compete with naive CD4+ T cells for IL-2 and exploit it for the induction of IL-10 production. Int Immunol (2005) 1.40
Variegated expression of CD8 alpha resulting from in situ deletion of regulatory sequences. Immunity (2002) 1.40
Ablation of thymic export causes accelerated decay of naive CD4 T cells in the periphery because of activation by environmental antigen. Proc Natl Acad Sci U S A (2008) 1.32
Dynamic imaging of experimental Leishmania donovani-induced hepatic granulomas detects Kupffer cell-restricted antigen presentation to antigen-specific CD8 T cells. PLoS Pathog (2010) 1.32
Modulation of dendritic cell function by naive and regulatory CD4+ T cells. J Immunol (2006) 1.31
Contribution of neural crest-derived cells in the embryonic and adult thymus. J Immunol (2008) 1.30
Differentiation of human T(H)-17 cells does require TGF-beta! Nat Immunol (2008) 1.27
IL-7-producing stromal cells are critical for lymph node remodeling. Blood (2012) 1.22
Differential influences of the aryl hydrocarbon receptor on Th17 mediated responses in vitro and in vivo. PLoS One (2013) 1.21
A major role for memory CD4 T cells in the control of lymphopenia-induced proliferation of naive CD4 T cells. J Immunol (2005) 1.17
Regulation and function of innate and adaptive interleukin-17-producing cells. EMBO Rep (2012) 1.14
IL7-hCD25 and IL7-Cre BAC transgenic mouse lines: new tools for analysis of IL-7 expressing cells. Genesis (2009) 1.12
The many lives of IL-9: a question of survival? Nat Immunol (2012) 1.11
Spartan: a comprehensive tool for understanding uncertainty in simulations of biological systems. PLoS Comput Biol (2013) 1.09
CD4 memory T cells survive and proliferate but fail to differentiate in the absence of CD40. J Exp Med (2006) 1.07
Cross presentation of antigen on MHC class II via the draining lymph node after corneal transplantation in mice. J Immunol (2008) 1.04
Galectin-1-expressing stromal cells constitute a specific niche for pre-BII cell development in mouse bone marrow. Blood (2011) 1.00
Identification of early gene expression changes during human Th17 cell differentiation. Blood (2012) 0.99
Chronic exposure to low levels of antigen in the periphery causes reversible functional impairment correlating with changes in CD5 levels in monoclonal CD8 T cells. J Immunol (2003) 0.99
T cell homeostasis in steady state and lymphopenic conditions. Immunol Lett (2006) 0.99
Natural killer receptors: the burden of a name. J Exp Med (2010) 0.98
Anatomical heterogeneity of memory CD4+ T cells due to reversible adaptation to the microenvironment. J Immunol (2004) 0.96
Functional specialization of memory Th cells revealed by expression of integrin CD49b. J Immunol (2006) 0.96
Noncognate interaction with MHC class II molecules is essential for maintenance of T cell metabolism to establish optimal memory CD4 T cell function. J Immunol (2007) 0.95
IL-7: the global builder of the innate lymphoid network and beyond, one niche at a time. Semin Immunol (2012) 0.94
CD25+CD4+ regulatory T cells and memory T cells prevent lymphopenia-induced proliferation of naive T cells in transient states of lymphopenia. J Immunol (2006) 0.94
IL-22 Protects Against Liver Pathology and Lethality of an Experimental Blood-Stage Malaria Infection. Front Immunol (2012) 0.94
Inhibition of receptor tyrosine kinases restores immunocompetence and improves immune-dependent chemotherapy against experimental leishmaniasis in mice. J Clin Invest (2010) 0.92
Dendritic cell functional properties in a three-dimensional tissue model of human lung mucosa. Am J Physiol Lung Cell Mol Physiol (2011) 0.91
Roles for TGF-beta and programmed cell death 1 ligand 1 in regulatory T cell expansion and diabetes suppression by zymosan in nonobese diabetic mice. J Immunol (2010) 0.91
Activation of CD8 T cells by antigen expressed in the pituitary gland. J Immunol (2002) 0.90
CD4 T cells guarantee optimal competitive fitness of CD8 memory T cells. Eur J Immunol (2004) 0.90
Dendritic cells matured by inflammation induce CD86-dependent priming of naive CD8+ T cells in the absence of their cognate peptide antigen. J Immunol (2009) 0.89
IL-22 mediates goblet cell hyperplasia and worm expulsion in intestinal helminth infection. PLoS Pathog (2013) 0.86
Th17 cells: An orphan with influence. Immunol Cell Biol (2007) 0.84
Phenotypic and functional profiling of CD4 T cell compartment in distinct populations of healthy adults with different antigenic exposure. PLoS One (2013) 0.83
Factors affecting the susceptibility of the mouse pituitary gland to CD8 T-cell-mediated autoimmunity. Immunology (2004) 0.83
Visualisation of lymphoid organ development. Methods Mol Biol (2010) 0.79
Tumor and CD4 T-cell interactions: tumor escape as result of reciprocal inactivation. Blood (2003) 0.79
Involvement of neurons and retinoic acid in lymphatic development: new insights in increased nuchal translucency. Prenat Diagn (2014) 0.78
Application of tissue engineering to the immune system: development of artificial lymph nodes. Front Immunol (2012) 0.77
Immunology: Cause of death matters. Nature (2009) 0.77
Innate lymphoid cells and type 2 (th2) mediated immune responses - pathogenic or beneficial? Front Immunol (2011) 0.76
Correction: Determining disease intervention strategies using spatially resolved simulations. PLoS One (2015) 0.75
Extending and Applying Spartan to Perform Temporal Sensitivity Analyses for Predicting Changes in Influential Biological Pathways in Computational Models. IEEE/ACM Trans Comput Biol Bioinform (2016) 0.75
Transduction of naive CD4 T cells with kinase-deficient Lck-HIV-Tat fusion protein dampens T cell activation and provokes a switch to regulatory function. Eur J Immunol (2005) 0.75