Published in Biotechniques on June 01, 2002
Linkage, association, and gene-expression analyses identify CNTNAP2 as an autism-susceptibility gene. Am J Hum Genet (2008) 7.13
Highly multiplexed molecular inversion probe genotyping: over 10,000 targeted SNPs genotyped in a single tube assay. Genome Res (2005) 6.32
A versatile assay for high-throughput gene expression profiling on universal array matrices. Genome Res (2004) 4.19
Joint modeling of linkage and association: identifying SNPs responsible for a linkage signal. Am J Hum Genet (2005) 3.62
On the replication of genetic associations: timing can be everything! Am J Hum Genet (2008) 3.32
Whole genome linkage disequilibrium maps in cattle. BMC Genet (2007) 3.28
Complexity reduction of polymorphic sequences (CRoPS): a novel approach for large-scale polymorphism discovery in complex genomes. PLoS One (2007) 2.92
A high-resolution linkage-disequilibrium map of the human major histocompatibility complex and first generation of tag single-nucleotide polymorphisms. Am J Hum Genet (2005) 2.85
Combining fMRI and SNP data to investigate connections between brain function and genetics using parallel ICA. Hum Brain Mapp (2009) 2.60
Single nucleotide polymorphism genotyping in polyploid wheat with the Illumina GoldenGate assay. Theor Appl Genet (2009) 2.56
A genome wide survey of SNP variation reveals the genetic structure of sheep breeds. PLoS One (2009) 2.22
Two methods of whole-genome amplification enable accurate genotyping across a 2320-SNP linkage panel. Genome Res (2004) 2.22
Increasing the power and efficiency of disease-marker case-control association studies through use of allele-sharing information. Am J Hum Genet (2004) 2.19
Genome-wide association studies: contribution of genomics to understanding blood pressure and essential hypertension. Curr Hypertens Rep (2010) 2.03
SNP arrays in heterogeneous tissue: highly accurate collection of both germline and somatic genetic information from unpaired single tumor samples. Am J Hum Genet (2008) 2.00
Guidelines for genotyping in genomewide linkage studies: single-nucleotide-polymorphism maps versus microsatellite maps. Am J Hum Genet (2004) 1.94
Association between IRF6 and nonsyndromic cleft lip with or without cleft palate in four populations. Genet Med (2007) 1.75
Singapore Genome Variation Project: a haplotype map of three Southeast Asian populations. Genome Res (2009) 1.73
Basic concepts of microarrays and potential applications in clinical microbiology. Clin Microbiol Rev (2009) 1.70
A high density SNP array for the domestic horse and extant Perissodactyla: utility for association mapping, genetic diversity, and phylogeny studies. PLoS Genet (2012) 1.66
High-throughput SNP discovery and genotyping for constructing a saturated linkage map of chickpea (Cicer arietinum L.). DNA Res (2012) 1.66
High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. PLoS Genet (2009) 1.61
High-resolution copy number analysis of paraffin-embedded archival tissue using SNP BeadArrays. Genome Res (2007) 1.61
An assessment of population structure in eight breeds of cattle using a whole genome SNP panel. BMC Genet (2008) 1.51
A gene-based linkage map for Bicyclus anynana butterflies allows for a comprehensive analysis of synteny with the lepidopteran reference genome. PLoS Genet (2009) 1.51
Construction of bovine whole-genome radiation hybrid and linkage maps using high-throughput genotyping. Anim Genet (2007) 1.49
Parallel gene analysis with allele-specific padlock probes and tag microarrays. Nucleic Acids Res (2003) 1.48
A high-density admixture scan in 1,670 African Americans with hypertension. PLoS Genet (2007) 1.47
Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot". PLoS Genet (2010) 1.47
Genetic variation in the one-carbon transfer pathway and ovarian cancer risk. Cancer Res (2008) 1.42
High resolution radiation hybrid maps of bovine chromosomes 19 and 29: comparison with the bovine genome sequence assembly. BMC Genomics (2007) 1.37
Comprehensive linkage and association analyses identify haplotype, near to the TNFSF15 gene, significantly associated with spondyloarthritis. PLoS Genet (2009) 1.36
Clock genes may influence bipolar disorder susceptibility and dysfunctional circadian rhythm. Am J Med Genet B Neuropsychiatr Genet (2008) 1.35
Family-based association of FKBP5 in bipolar disorder. Mol Psychiatry (2008) 1.34
Dissection of genetic factors modulating fetal growth in cattle indicates a substantial role of the non-SMC condensin I complex, subunit G (NCAPG) gene. Genetics (2009) 1.34
Genomic diversity and evolution of Mycobacterium ulcerans revealed by next-generation sequencing. PLoS Pathog (2009) 1.33
A third base pair for the polymerase chain reaction: inserting isoC and isoG. Nucleic Acids Res (2004) 1.30
Model SNP development for complex genomes based on hexaploid oat using high-throughput 454 sequencing technology. BMC Genomics (2011) 1.29
HLA-DQA1-HLA-DRB1 variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants. Nat Genet (2014) 1.27
Association genetics of coastal Douglas fir (Pseudotsuga menziesii var. menziesii, Pinaceae). I. Cold-hardiness related traits. Genetics (2009) 1.27
Genetic variation in tumor necrosis factor and the nuclear factor-kappaB canonical pathway and risk of non-Hodgkin's lymphoma. Cancer Epidemiol Biomarkers Prev (2008) 1.26
Asthma and genes encoding components of the vitamin D pathway. Respir Res (2009) 1.26
ProbeMaker: an extensible framework for design of sets of oligonucleotide probes. BMC Bioinformatics (2005) 1.23
High throughput SNP and expression analyses of candidate genes for non-syndromic oral clefts. J Med Genet (2006) 1.20
A Hybrid Machine Learning Method for Fusing fMRI and Genetic Data: Combining both Improves Classification of Schizophrenia. Front Hum Neurosci (2010) 1.18
Probing the functional impact of sequence variation on p53-DNA interactions using a novel microsphere assay for protein-DNA binding with human cell extracts. PLoS Genet (2009) 1.17
Polymorphisms in mitochondrial genes and prostate cancer risk. Cancer Epidemiol Biomarkers Prev (2008) 1.17
Transcriptional profiling of degraded RNA in cryopreserved and fixed tissue samples obtained at autopsy. BMC Clin Pathol (2006) 1.17
Maternal transmission effects of the PAX genes among cleft case-parent trios from four populations. Eur J Hum Genet (2009) 1.14
Assessment of hepatocyte growth factor in ovarian cancer mortality. Cancer Epidemiol Biomarkers Prev (2011) 1.14
Evaluating HapMap SNP data transferability in a large-scale genotyping project involving 175 cancer-associated genes. Hum Genet (2005) 1.13
PRKCA: a positional candidate gene for body mass index and asthma. Am J Hum Genet (2009) 1.11
New methods for finding disease-susceptibility genes: impact and potential. Genome Biol (2003) 1.11
Investigating the utility of combining phi29 whole genome amplification and highly multiplexed single nucleotide polymorphism BeadArray genotyping. BMC Biotechnol (2004) 1.11
In vitro vs in silico detected SNPs for the development of a genotyping array: what can we learn from a non-model species? PLoS One (2010) 1.11
Physiogenomic analysis of the Puerto Rican population. Pharmacogenomics (2009) 1.11
SNPWave: a flexible multiplexed SNP genotyping technology. Nucleic Acids Res (2004) 1.10
CYP2C19 variation and citalopram response. Pharmacogenet Genomics (2011) 1.09
A first generation whole genome RH map of the river buffalo with comparison to domestic cattle. BMC Genomics (2008) 1.08
Development of an integrated genome informatics, data management and workflow infrastructure: a toolbox for the study of complex disease genetics. Hum Genomics (2004) 1.08
Genetic interactions controlling sex and color establish the potential for sexual conflict in Lake Malawi cichlid fishes. Heredity (Edinb) (2012) 1.07
Genetic variation in the chromosome 17q23 amplicon and breast cancer risk. Cancer Epidemiol Biomarkers Prev (2009) 1.05
Genetic variation in stromal proteins decorin and lumican with breast cancer: investigations in two case-control studies. Breast Cancer Res (2008) 1.04
Germline variation in apoptosis pathway genes and risk of non-Hodgkin's lymphoma. Cancer Epidemiol Biomarkers Prev (2010) 1.04
Sequence- vs. chip-assisted genomic selection: accurate biological information is advised. Genet Sel Evol (2015) 1.04
Genetics of gestational diabetes mellitus and type 2 diabetes. Diabetes Care (2007) 1.03
Centrosome-related genes, genetic variation, and risk of breast cancer. Breast Cancer Res Treat (2010) 1.03
Association mapping of spot blotch resistance in wild barley. Mol Breed (2010) 1.02
High quality genome-wide genotyping from archived dried blood spots without DNA amplification. PLoS One (2013) 1.02
Evidence that TGFA influences risk to cleft lip with/without cleft palate through unconventional genetic mechanisms. Hum Genet (2009) 1.01
Differential parental transmission of markers in RUNX2 among cleft case-parent trios from four populations. Genet Epidemiol (2008) 1.01
Genomewide high-density SNP linkage analysis of non-BRCA1/2 breast cancer families identifies various candidate regions and has greater power than microsatellite studies. BMC Genomics (2007) 1.01
Transcriptome coexpression map of human embryonic stem cells. BMC Genomics (2006) 1.01
Candidate gene analysis using imputed genotypes: cell cycle single-nucleotide polymorphisms and ovarian cancer risk. Cancer Epidemiol Biomarkers Prev (2009) 1.01
Polymorphisms in ABCB1 and ERCC2 associated with ovarian cancer outcome. Int J Mol Epidemiol Genet (2011) 1.00
A low-cost open-source SNP genotyping platform for association mapping applications. Genome Biol (2005) 1.00
The use of SNP markers for linkage mapping in diploid and tetraploid peanuts. G3 (Bethesda) (2014) 0.99
Genomewide linkage scan of schizophrenia in a large multicenter pedigree sample using single nucleotide polymorphisms. Mol Psychiatry (2009) 0.99
Haplotype diversity in 11 candidate genes across four populations. Genetics (2005) 0.99
Markers of B-vitamin deficiency and frailty in older women. J Nutr Health Aging (2008) 0.98
Guided exploration of genomic risk for gray matter abnormalities in schizophrenia using parallel independent component analysis with reference. Neuroimage (2013) 0.98
High-density SNP association study of the 17q21 chromosomal region linked to autism identifies CACNA1G as a novel candidate gene. Mol Psychiatry (2009) 0.97
Linkage disequilibrium and signatures of selection on chromosomes 19 and 29 in beef and dairy cattle. Anim Genet (2008) 0.97
Genetic associations of brain structural networks in schizophrenia: a preliminary study. Biol Psychiatry (2010) 0.97
Genetic determinants of target and novelty-related event-related potentials in the auditory oddball response. Neuroimage (2009) 0.96
An approach based on a genome-wide association study reveals candidate loci for narcolepsy. Hum Genet (2010) 0.96
Genome-wide association mapping for kernel and malting quality traits using historical European barley records. PLoS One (2014) 0.95
Genome-wide DNA methylation analysis in cohesin mutant human cell lines. Nucleic Acids Res (2010) 0.95
CYP2C9 and VKORC1 genotypes in Puerto Ricans: A case for admixture-matching in clinical pharmacogenetic studies. Clin Chim Acta (2010) 0.93
Polymorphisms in NF-kappaB inhibitors and risk of epithelial ovarian cancer. BMC Cancer (2009) 0.93
Genome-wide SNP identification in multiple morphotypes of allohexaploid tall fescue (Festuca arundinacea Schreb). BMC Genomics (2012) 0.93
Cost-effective prediction of gender-labeling errors and estimation of gender-labeling error rates in candidate-gene association studies. Front Genet (2011) 0.92
Optimization of microfluidic microsphere-trap arrays. Biomicrofluidics (2013) 0.92
Identification and correction of previously unreported spatial phenomena using raw Illumina BeadArray data. BMC Bioinformatics (2010) 0.92
Analysis of candidate genes on chromosome 2 in oral cleft case-parent trios from three populations. Hum Genet (2006) 0.91
Perspectives and limitations of gene expression profiling in rheumatology: new molecular strategies. Arthritis Res Ther (2004) 0.90
Integrating the multiple dimensions of genomic and epigenomic landscapes of cancer. Cancer Metastasis Rev (2010) 0.90
The genetic basis of a complex functional system. Evolution (2012) 0.90
Risk of ovarian cancer and inherited variants in relapse-associated genes. PLoS One (2010) 0.90
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
Genome-wide detection and characterization of positive selection in human populations. Nature (2007) 17.27
High-resolution genomic profiling of chromosomal aberrations using Infinium whole-genome genotyping. Genome Res (2006) 10.45
High-throughput DNA methylation profiling using universal bead arrays. Genome Res (2006) 8.05
A genome-wide scalable SNP genotyping assay using microarray technology. Nat Genet (2005) 7.64
Whole-genome genotyping with the single-base extension assay. Nat Methods (2006) 6.66
A novel, high-performance random array platform for quantitative gene expression profiling. Genome Res (2004) 4.32
Highly parallel genomic assays. Nat Rev Genet (2006) 4.24
A versatile assay for high-throughput gene expression profiling on universal array matrices. Genome Res (2004) 4.19
Profiling alternative splicing on fiber-optic arrays. Nat Biotechnol (2002) 3.94
Differential allelic expression in the human genome: a robust approach to identify genetic and epigenetic cis-acting mechanisms regulating gene expression. PLoS Genet (2008) 3.92
Decoding randomly ordered DNA arrays. Genome Res (2004) 3.49
Human embryonic stem cells have a unique epigenetic signature. Genome Res (2006) 2.89
FusionSeq: a modular framework for finding gene fusions by analyzing paired-end RNA-sequencing data. Genome Biol (2010) 2.79
A highly informative SNP linkage panel for human genetic studies. Nat Methods (2004) 2.74
Discovery of non-ETS gene fusions in human prostate cancer using next-generation RNA sequencing. Genome Res (2010) 2.50
N-myc downstream regulated gene 1 (NDRG1) is fused to ERG in prostate cancer. Neoplasia (2009) 1.68
Detection of low prevalence somatic mutations in solid tumors with ultra-deep targeted sequencing. Genome Biol (2011) 1.60
Genome wide profiling of human embryonic stem cells (hESCs), their derivatives and embryonal carcinoma cells to develop base profiles of U.S. Federal government approved hESC lines. BMC Dev Biol (2006) 1.58
Microarray-based multicycle-enrichment of genomic subsets for targeted next-generation sequencing. Genome Res (2009) 1.55
Efficient strategies for the conjugation of oligonucleotides to antibodies enabling highly sensitive protein detection. Biopolymers (2004) 0.96
A multiplexed protein kinase assay. Chembiochem (2007) 0.90
New details of HCV NS3/4A proteinase functionality revealed by a high-throughput cleavage assay. PLoS One (2012) 0.90
High-resolution analysis and functional mapping of cleavage sites and substrate proteins of furin in the human proteome. PLoS One (2013) 0.89
BeadArray-based solutions for enabling the promise of pharmacogenomics. Biotechniques (2005) 0.84
A highly scalable peptide-based assay system for proteomics. PLoS One (2012) 0.83
A method for rapid protease substrate evaluation and optimization. Comb Chem High Throughput Screen (2006) 0.83
Significant improvement of quality for long oligonucleotides by using controlled pore glass with large pores. Nucleosides Nucleotides Nucleic Acids (2005) 0.78
Evaluation of different chemical strategies for conjugation of oligonucleotides to peptides. Nucleosides Nucleotides Nucleic Acids (2007) 0.77
A high-complexity, multiplexed solution-phase assay for profiling protease activity on microarrays. Comb Chem High Throughput Screen (2008) 0.77
Retention of histidine-containing peptides on a nickel affinity column. J Chromatogr Sci (2007) 0.75