Published in Mol Cell Biol on August 01, 2002
Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex. Genes Dev (2008) 3.90
Deconstructing repression: evolving models of co-repressor action. Nat Rev Genet (2010) 3.29
Transcriptional and DNA binding activity of the Foxp1/2/4 family is modulated by heterotypic and homotypic protein interactions. Mol Cell Biol (2004) 2.48
Inactivation of CtIP leads to early embryonic lethality mediated by G1 restraint and to tumorigenesis by haploid insufficiency. Mol Cell Biol (2005) 2.30
C-terminal-binding protein corepresses epithelial and proapoptotic gene expression programs. Proc Natl Acad Sci U S A (2003) 2.25
Retracted Metabolic regulation of SIRT1 transcription via a HIC1:CtBP corepressor complex. Proc Natl Acad Sci U S A (2007) 2.09
C-terminal-binding protein directly activates and represses Wnt transcriptional targets in Drosophila. EMBO J (2006) 2.01
Transcription factor YY1 functions as a PcG protein in vivo. EMBO J (2003) 1.95
RBP-Jkappa/SHARP recruits CtIP/CtBP corepressors to silence Notch target genes. Mol Cell Biol (2005) 1.72
A network of Krüppel-like Factors (Klfs). Klf8 is repressed by Klf3 and activated by Klf1 in vivo. J Biol Chem (2008) 1.72
PKCeta is required for beta1gamma2/beta3gamma2- and PKD-mediated transport to the cell surface and the organization of the Golgi apparatus. J Cell Biol (2005) 1.59
A SIRT1-LSD1 corepressor complex regulates Notch target gene expression and development. Mol Cell (2011) 1.55
YY1 DNA binding and PcG recruitment requires CtBP. Genes Dev (2004) 1.52
HMG box transcription factor TCF-4's interaction with CtBP1 controls the expression of the Wnt target Axin2/Conductin in human embryonic kidney cells. Nucleic Acids Res (2003) 1.49
Role of the PLDLS-binding cleft region of CtBP1 in recruitment of core and auxiliary components of the corepressor complex. Mol Cell Biol (2007) 1.49
CtIP activates its own and cyclin D1 promoters via the E2F/RB pathway during G1/S progression. Mol Cell Biol (2006) 1.48
A role for BARS at the fission step of COPI vesicle formation from Golgi membrane. EMBO J (2005) 1.48
Interaction of Brn3a and HIPK2 mediates transcriptional repression of sensory neuron survival. J Cell Biol (2004) 1.46
HIC1 attenuates Wnt signaling by recruitment of TCF-4 and beta-catenin to the nuclear bodies. EMBO J (2006) 1.41
CtBP is an essential corepressor for BCL6 autoregulation. Mol Cell Biol (2008) 1.41
Specific recognition of ZNF217 and other zinc finger proteins at a surface groove of C-terminal binding proteins. Mol Cell Biol (2006) 1.36
Homeodomain-interacting protein kinase-2 mediates CtBP phosphorylation and degradation in UV-triggered apoptosis. Proc Natl Acad Sci U S A (2005) 1.35
Increased frequency of de novo copy number variants in congenital heart disease by integrative analysis of single nucleotide polymorphism array and exome sequence data. Circ Res (2014) 1.32
Interaction of MEQ protein and C-terminal-binding protein is critical for induction of lymphomas by Marek's disease virus. Proc Natl Acad Sci U S A (2006) 1.29
The Golgi mitotic checkpoint is controlled by BARS-dependent fission of the Golgi ribbon into separate stacks in G2. EMBO J (2007) 1.22
What drives cell morphogenesis: a look inside the vertebrate photoreceptor. Dev Dyn (2009) 1.21
The spatial distribution of glutamatergic inputs to dendrites of retinal ganglion cells. J Comp Neurol (2008) 1.17
Ribeye is required for presynaptic Ca(V)1.3a channel localization and afferent innervation of sensory hair cells. Development (2011) 1.17
Nuclear speckle-associated protein Pnn/DRS binds to the transcriptional corepressor CtBP and relieves CtBP-mediated repression of the E-cadherin gene. Mol Cell Biol (2004) 1.15
The conserved NAD(H)-dependent corepressor CTBP-1 regulates Caenorhabditis elegans life span. Proc Natl Acad Sci U S A (2009) 1.14
The evolving understanding of COPI vesicle formation. Nat Rev Mol Cell Biol (2009) 1.14
Mechanisms directing the nuclear localization of the CtBP family proteins. Mol Cell Biol (2006) 1.13
Genome-wide profiles of CtBP link metabolism with genome stability and epithelial reprogramming in breast cancer. Nat Commun (2013) 1.13
CtBPs promote cell survival through the maintenance of mitotic fidelity. Mol Cell Biol (2009) 1.12
Therapeutic targeting of C-terminal binding protein in human cancer. Cell Cycle (2010) 1.12
Spark: a navigational paradigm for genomic data exploration. Genome Res (2012) 1.10
Evolutionary functional analysis and molecular regulation of the ZEB transcription factors. Cell Mol Life Sci (2012) 1.06
Role of the C-terminal binding protein PXDLS motif binding cleft in protein interactions and transcriptional repression. Mol Cell Biol (2006) 1.04
Expression of CtBP family protein isoforms in breast cancer and their role in chemoresistance. Biol Cell (2010) 1.03
Krüppel-like zinc finger protein Gli-similar 2 (Glis2) represses transcription through interaction with C-terminal binding protein 1 (CtBP1). Nucleic Acids Res (2005) 1.02
The oligomeric state of CtBP determines its role as a transcriptional co-activator and co-repressor of Wingless targets. EMBO J (2011) 1.02
Transcriptional repression: conserved and evolved features. Curr Biol (2010) 1.02
Congenital diaphragmatic hernia candidate genes derived from embryonic transcriptomes. Proc Natl Acad Sci U S A (2012) 1.01
Multiple domains of the Receptor-Interacting Protein 140 contribute to transcription inhibition. Nucleic Acids Res (2004) 1.01
Control of endothelial sprouting by a Tel-CtBP complex. Nat Cell Biol (2010) 0.99
ZNF217, a candidate breast cancer oncogene amplified at 20q13, regulates expression of the ErbB3 receptor tyrosine kinase in breast cancer cells. Oncogene (2010) 0.99
Tcf21 regulates the specification and maturation of proepicardial cells. Development (2013) 0.98
Identification of a second CtBP binding site in adenovirus type 5 E1A conserved region 3. J Virol (2008) 0.96
Role of the unique N-terminal domain of CtBP2 in determining the subcellular localisation of CtBP family proteins. BMC Cell Biol (2006) 0.94
Porcine muscle sensory attributes associate with major changes in gene networks involving CAPZB, ANKRD1, and CTBP2. Funct Integr Genomics (2009) 0.94
CtBP contributes quantitatively to Knirps repression activity in an NAD binding-dependent manner. Mol Cell Biol (2004) 0.93
Evidence that mono-ADP-ribosylation of CtBP1/BARS regulates lipid storage. Mol Biol Cell (2007) 0.92
CtBP2 Promotes Human Cancer Cell Migration by Transcriptional Activation of Tiam1. Genes Cancer (2012) 0.92
How to make a synaptic ribbon: RIBEYE deletion abolishes ribbons in retinal synapses and disrupts neurotransmitter release. EMBO J (2016) 0.91
Ligand-dependent corepressor LCoR is an attenuator of progesterone-regulated gene expression. J Biol Chem (2009) 0.90
PLDLS-dependent interaction of E1A with CtBP: regulation of CtBP nuclear localization and transcriptional functions. Oncogene (2007) 0.90
KLF3 regulates muscle-specific gene expression and synergizes with serum response factor on KLF binding sites. Mol Cell Biol (2010) 0.90
C-terminal binding protein and poly(ADP)ribose polymerase 1 contribute to repression of the p21(waf1/cip1) promoter. Oncogene (2010) 0.89
A critical period in cortical interneuron neurogenesis in down syndrome revealed by human neural progenitor cells. Dev Neurosci (2009) 0.89
Mechanisms of COPI vesicle formation. FEBS Lett (2009) 0.88
Golgi membrane dynamics and lipid metabolism. Curr Biol (2012) 0.88
Components and properties of the G3 ganglion cell circuit in the rabbit retina. J Comp Neurol (2009) 0.87
Corepressor CtBP and nuclear speckle protein Pnn/DRS differentially modulate transcription and splicing of the E-cadherin gene. Mol Cell Biol (2007) 0.86
Differential spatial expression and subcellular localization of CtBP family members in rodent brain. PLoS One (2012) 0.86
Delayed differentiation in embryonic stem cells and mesodermal progenitors in the absence of CtBP2. Mech Dev (2009) 0.86
CtBP2 is an independent prognostic marker that promotes GLI1 induced epithelial-mesenchymal transition in hepatocellular carcinoma. Oncotarget (2015) 0.85
Small Molecule, NSC95397, Inhibits the CtBP1-Protein Partner Interaction and CtBP1-Mediated Transcriptional Repression. J Biomol Screen (2014) 0.85
C-Terminal Binding Protein: A Molecular Link between Metabolic Imbalance and Epigenetic Regulation in Breast Cancer. Int J Cell Biol (2013) 0.84
GATA proteins work together with friend of GATA (FOG) and C-terminal binding protein (CTBP) co-regulators to control adipogenesis. J Biol Chem (2010) 0.83
Developmental expression and phylogenetic conservation of alternatively spliced forms of the C-terminal binding protein corepressor. Dev Genes Evol (2006) 0.83
CtBP and associated LSD1 are required for transcriptional activation by NeuroD1 in gastrointestinal endocrine cells. Mol Cell Biol (2014) 0.82
Inhibition of CtBP1 activity by Akt-mediated phosphorylation. J Mol Biol (2010) 0.82
Components of the CtBP1/BARS-dependent fission machinery. Histochem Cell Biol (2013) 0.82
Conserved catalytic and C-terminal regulatory domains of the C-terminal binding protein corepressor fine-tune the transcriptional response in development. Mol Cell Biol (2010) 0.81
Properties of the ON bistratified ganglion cell in the rabbit retina. J Comp Neurol (2013) 0.81
Bioinformatics identification of modules of transcription factor binding sites in Alzheimer's disease-related genes by in silico promoter analysis and microarrays. Int J Alzheimers Dis (2011) 0.81
CtBP2 downregulation during neural crest specification induces expression of Mitf and REST, resulting in melanocyte differentiation and sympathoadrenal lineage suppression. Mol Cell Biol (2011) 0.81
A recurrent de novo CTBP1 mutation is associated with developmental delay, hypotonia, ataxia, and tooth enamel defects. Neurogenetics (2016) 0.80
Interaction of CtBP with adenovirus E1A suppresses immortalization of primary epithelial cells and enhances virus replication during productive infection. Virology (2013) 0.80
CtBP2 proteome: Role of CtBP in E2F7-mediated repression and cell proliferation. Genes Cancer (2014) 0.78
The ribbon-associated protein C-terminal-binding protein 1 is not essential for the structure and function of retinal ribbon synapses. Mol Vis (2013) 0.78
PAK1 and CtBP1 Regulate the Coupling of Neuronal Activity to Muscle Chromatin and Gene Expression. Mol Cell Biol (2015) 0.78
CtBP maintains cancer cell growth and metabolic homeostasis via regulating SIRT4. Cell Death Dis (2015) 0.78
The corepressor CTBP2 is a coactivator of retinoic acid receptor/retinoid X receptor in retinoic acid signaling. Mol Cell Biol (2013) 0.78
C-terminal binding proteins (CtBPs) attenuate KLF4-mediated transcriptional activation. FEBS Lett (2009) 0.78
Post-Translational Modifications of Histones in Vertebrate Neurogenesis. Front Neurosci (2015) 0.78
Alternative splicing regulates Prdm1/Blimp-1 DNA binding activities and corepressor interactions. Mol Cell Biol (2012) 0.78
Changes in ovarian protein expression during primordial follicle formation in the hamster. Mol Cell Endocrinol (2011) 0.77
Nicotinamide adenine dinucleotide-induced multimerization of the co-repressor CtBP1 relies on a switching tryptophan. J Biol Chem (2013) 0.77
Involvement of CtBP2 in LPS-induced microglial activation. J Mol Histol (2012) 0.77
Drosophila CtBP regulates proliferation and differentiation of eye precursors and complexes with Eyeless, Dachshund, Dan, and Danr during eye and antennal development. Dev Dyn (2010) 0.77
Inhibition of transcriptional activation and cell proliferation activities of adenovirus E1A by the unique N-terminal domain of CtBP2. Oncogene (2008) 0.76
Transforming activity and therapeutic targeting of C-terminal-binding protein 2 in Apc-mutated neoplasia. Oncogene (2017) 0.76
Oligomeric form of CtBP coactivates NeuroD1-mediated transcription. FEBS Lett (2016) 0.75
Pinin interacts with C-terminal binding proteins for RNA alternative splicing and epithelial cell identity of human ovarian cancer cells. Oncotarget (2016) 0.75
Functional characterization of rare FOXP2 variants in neurodevelopmental disorder. J Neurodev Disord (2016) 0.75
Elucidating the mechanisms of transcription regulation during heart development by next-generation sequencing. J Hum Genet (2015) 0.75
CtBP1 overexpression in keratinocytes perturbs skin homeostasis. J Invest Dermatol (2013) 0.75
Expression and prognostic significance of CTBP2 in human gliomas. Oncol Lett (2016) 0.75
C-terminal binding proteins are essential pro-survival factors that undergo caspase-dependent downregulation during neuronal apoptosis. Mol Cell Neurosci (2013) 0.75
Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer. Proc Natl Acad Sci U S A (1988) 35.13
Mammalian Ras interacts directly with the serine/threonine kinase Raf. Cell (1993) 16.91
Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice. Genes Dev (1991) 13.28
Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression. Cell (1997) 7.64
Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src. Mol Cell Biol (1994) 7.53
An LDL-receptor-related protein mediates Wnt signalling in mice. Nature (2000) 6.34
Placental development: lessons from mouse mutants. Nat Rev Genet (2001) 6.03
Regulation of skeletal myogenesis by association of the MEF2 transcription factor with class II histone deacetylases. Mol Cell (2000) 5.13
Wnt-3a regulates somite and tailbud formation in the mouse embryo. Genes Dev (1994) 3.77
Identification of sequences required for the efficient localization of the focal adhesion kinase, pp125FAK, to cellular focal adhesions. J Cell Biol (1993) 3.64
The glial cells missing-1 protein is essential for branching morphogenesis in the chorioallantoic placenta. Nat Genet (2000) 3.49
Molecular cloning and characterization of a cellular phosphoprotein that interacts with a conserved C-terminal domain of adenovirus E1A involved in negative modulation of oncogenic transformation. Proc Natl Acad Sci U S A (1995) 3.28
RIBEYE, a component of synaptic ribbons: a protein's journey through evolution provides insight into synaptic ribbon function. Neuron (2000) 3.21
Evidence for a function of CtBP in epithelial gene regulation and anoikis. Oncogene (2000) 3.14
T (Brachyury) is a direct target of Wnt3a during paraxial mesoderm specification. Genes Dev (1999) 3.13
A Smad transcriptional corepressor. Cell (1999) 3.07
Cloning and characterization of mCtBP2, a co-repressor that associates with basic Krüppel-like factor and other mammalian transcriptional regulators. EMBO J (1998) 3.06
Wnt3a-/--like phenotype and limb deficiency in Lef1(-/-)Tcf1(-/-) mice. Genes Dev (1999) 2.94
CtBP/BARS induces fission of Golgi membranes by acylating lysophosphatidic acid. Nature (1999) 2.81
Drosophila CtBP: a Hairy-interacting protein required for embryonic segmentation and hairy-mediated transcriptional repression. EMBO J (1998) 2.74
ZEB represses transcription through interaction with the corepressor CtBP. Proc Natl Acad Sci U S A (1999) 2.64
Requirement of the MADS-box transcription factor MEF2C for vascular development. Development (1998) 2.63
Interaction of short-range repressors with Drosophila CtBP in the embryo. Science (1998) 2.61
Shroom, a PDZ domain-containing actin-binding protein, is required for neural tube morphogenesis in mice. Cell (1999) 2.56
XCtBP is a XTcf-3 co-repressor with roles throughout Xenopus development. Development (1999) 2.56
Mutations in TGIF cause holoprosencephaly and link NODAL signalling to human neural axis determination. Nat Genet (2000) 2.53
Association of COOH-terminal-binding protein (CtBP) and MEF2-interacting transcription repressor (MITR) contributes to transcriptional repression of the MEF2 transcription factor. J Biol Chem (2001) 2.45
Monoclonal antibodies specific for the carboxy terminus of simian virus 40 large T antigen. J Virol (1984) 2.41
C-Terminal binding protein is a transcriptional repressor that interacts with a specific class of vertebrate Polycomb proteins. Mol Cell Biol (1999) 1.97
Analysis of the vestigial tail mutation demonstrates that Wnt-3a gene dosage regulates mouse axial development. Genes Dev (1996) 1.94
The CtBP family: enigmatic and enzymatic transcriptional co-repressors. Bioessays (2001) 1.86
DeltaEF1, a zinc finger and homeodomain transcription factor, is required for skeleton patterning in multiple lineages. Development (1998) 1.83
Ikaros interactions with CtBP reveal a repression mechanism that is independent of histone deacetylase activity. J Biol Chem (2000) 1.81
Net, a negative Ras-switchable TCF, contains a second inhibition domain, the CID, that mediates repression through interactions with CtBP and de-acetylation. EMBO J (1999) 1.76
ZEB, a vertebrate homolog of Drosophila Zfh-1, is a negative regulator of muscle differentiation. EMBO J (1997) 1.71
A dynamic role for HDAC7 in MEF2-mediated muscle differentiation. J Biol Chem (2001) 1.68
A recombinant murine retrovirus for simian virus 40 large T cDNA transforms mouse fibroblasts to anchorage-independent growth. J Virol (1986) 1.68
Multiple modes of repression by the Smad transcriptional corepressor TGIF. J Biol Chem (1999) 1.61
Identification of CtBP1 and CtBP2 as corepressors of zinc finger-homeodomain factor deltaEF1. Mol Cell Biol (1999) 1.57
JunB is essential for mammalian placentation. EMBO J (1999) 1.57
The carboxy-terminal region of adenovirus E1A activates transcription through targeting of a C-terminal binding protein-histone deacetylase complex. FEBS Lett (1998) 1.55
The corepressor CtBP interacts with Evi-1 to repress transforming growth factor beta signaling. Blood (2001) 1.53
The interaction of the carboxyl terminus-binding protein with the Smad corepressor TGIF is disrupted by a holoprosencephaly mutation in TGIF. J Biol Chem (2000) 1.49
FOG acts as a repressor of red blood cell development in Xenopus. Development (2000) 1.42
Molecular cloning and functional characterization of brefeldin A-ADP-ribosylated substrate. A novel protein involved in the maintenance of the Golgi structure. J Biol Chem (1999) 1.39
Drosophila C-terminal binding protein functions as a context-dependent transcriptional co-factor and interferes with both mad and groucho transcriptional repression. J Biol Chem (2000) 1.39
The N-terminal BTB/POZ domain and C-terminal sequences are essential for Tramtrack69 to specify cell fate in the developing Drosophila eye. Genetics (2000) 1.14
E-MAP-115, encoding a microtubule-associated protein, is a retinoic acid-inducible gene required for spermatogenesis. Genes Dev (2000) 1.06
CtBP-dependent activities of the short-range Giant repressor in the Drosophila embryo. Proc Natl Acad Sci U S A (2001) 1.05
Functional knockout of the corepressor CtBP by the second exon of adenovirus E1a relieves repression of transcription. Exp Cell Res (2001) 0.98
Isolation and characterization of a novel zinc finger gene, ZNF219, and mapping to the human chromosome 14q11 region. DNA Res (2000) 0.83
The knockout mouse project. Nat Genet (2004) 7.80
High-efficiency FLP and PhiC31 site-specific recombination in mammalian cells. PLoS One (2007) 3.84
The International Gene Trap Consortium Website: a portal to all publicly available gene trap cell lines in mouse. Nucleic Acids Res (2006) 3.40
Roles of PDGF in animal development. Development (2003) 2.87
Evolutionary divergence of platelet-derived growth factor alpha receptor signaling mechanisms. Mol Cell Biol (2003) 2.85
Inhibition of gap junction communication at ectopic Eph/ephrin boundaries underlies craniofrontonasal syndrome. PLoS Biol (2006) 2.43
Ephrin-B1 forward and reverse signaling are required during mouse development. Genes Dev (2004) 2.28
[Beta]IV-spectrin regulates sodium channel clustering through ankyrin-G at axon initial segments and nodes of Ranvier. J Cell Biol (2002) 2.15
Cell autonomous requirement for PDGFRalpha in populations of cranial and cardiac neural crest cells. Development (2003) 2.07
Cryptic boundaries in roof plate and choroid plexus identified by intersectional gene activation. Nat Genet (2003) 1.95
Ephrin signaling in vivo: look both ways. Dev Dyn (2005) 1.93
Additive effects of PDGF receptor beta signaling pathways in vascular smooth muscle cell development. PLoS Biol (2003) 1.91
A specific requirement for PDGF-C in palate formation and PDGFR-alpha signaling. Nat Genet (2004) 1.87
Identification and validation of PDGF transcriptional targets by microarray-coupled gene-trap mutagenesis. Nat Genet (2004) 1.85
PDGF signaling specificity is mediated through multiple immediate early genes. Nat Genet (2006) 1.83
An allelic series at the PDGFalphaR locus indicates unequal contributions of distinct signaling pathways during development. Dev Cell (2002) 1.70
Increased PDGFRalpha activation disrupts connective tissue development and drives systemic fibrosis. Dev Cell (2009) 1.61
In vivo convergence of BMP and MAPK signaling pathways: impact of differential Smad1 phosphorylation on development and homeostasis. Genes Dev (2004) 1.52
PDGFRβ signaling regulates mural cell plasticity and inhibits fat development. Dev Cell (2011) 1.45
Context-specific requirements for Fgfr1 signaling through Frs2 and Frs3 during mouse development. Development (2006) 1.38
Ephrin-B2 forward signaling regulates somite patterning and neural crest cell development. Dev Biol (2006) 1.27
The PDGF signaling pathway controls multiple steroid-producing lineages. Genes Dev (2008) 1.21
PDGFR-alpha signaling is critical for tooth cusp and palate morphogenesis. Dev Dyn (2005) 1.18
Ephrin-B1 forward signaling regulates craniofacial morphogenesis by controlling cell proliferation across Eph-ephrin boundaries. Genes Dev (2010) 1.17
Ephrin-B1 regulates axon guidance by reverse signaling through a PDZ-dependent mechanism. Genes Dev (2009) 1.17
The widely used Wnt1-Cre transgene causes developmental phenotypes by ectopic activation of Wnt signaling. Dev Biol (2013) 1.16
Regulation of neural progenitor cell state by ephrin-B. J Cell Biol (2008) 1.13
Gene trap mutagenesis in embryonic stem cells. Methods Enzymol (2003) 0.92
Gene trap mutagenesis in the mouse. Methods Enzymol (2010) 0.91
A critical role for PDGFRα signaling in medial nasal process development. PLoS Genet (2013) 0.89
Engineering mutations: deconstructing the mouse gene by gene. Dev Dyn (2006) 0.88
Eph/ephrin signaling: genetic, phosphoproteomic, and transcriptomic approaches. Semin Cell Dev Biol (2011) 0.87
PI3K-mediated PDGFRα signaling regulates survival and proliferation in skeletal development through p53-dependent intracellular pathways. Genes Dev (2014) 0.86
ROSA26Flpo deleter mice promote efficient inversion of conditional gene traps in vivo. Genesis (2010) 0.85
Clonal expansion analysis of transposon insertions by high-throughput sequencing identifies candidate cancer genes in a PiggyBac mutagenesis screen. PLoS One (2013) 0.82
Mouse development: from black eyes to knockouts. Dev Dyn (2006) 0.75
Genotyping Embryonic Stem (ES) Cell Colonies Prior to Picking. CSH Protoc (2006) 0.75