Published in J Mol Biol on January 03, 2003
A glutathione transferase from Agrobacterium tumefaciens reveals a novel class of bacterial GST superfamily. PLoS One (2012) 0.78
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CD1d-lipid-antigen recognition by the semi-invariant NKT T-cell receptor. Nature (2007) 5.31
MR1 presents microbial vitamin B metabolites to MAIT cells. Nature (2012) 3.71
AB5 subtilase cytotoxin inactivates the endoplasmic reticulum chaperone BiP. Nature (2006) 3.65
A common fold mediates vertebrate defense and bacterial attack. Science (2007) 3.43
A structural basis for the selection of dominant alphabeta T cell receptors in antiviral immunity. Immunity (2003) 3.41
Somatically acquired JAK1 mutations in adult acute lymphoblastic leukemia. J Exp Med (2008) 3.24
Germline-encoded recognition of diverse glycolipids by natural killer T cells. Nat Immunol (2007) 3.19
Structural determinants of T-cell receptor bias in immunity. Nat Rev Immunol (2006) 3.01
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Differential recognition of CD1d-alpha-galactosyl ceramide by the V beta 8.2 and V beta 7 semi-invariant NKT T cell receptors. Immunity (2009) 2.61
A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule. Nat Immunol (2007) 2.55
How insulin engages its primary binding site on the insulin receptor. Nature (2013) 2.52
T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I-bound peptide. Nat Immunol (2005) 2.52
Analysis of glutathione: implication in redox and detoxification. Clin Chim Acta (2003) 2.48
Immune self-reactivity triggered by drug-modified HLA-peptide repertoire. Nature (2012) 2.46
Lack of prominent peptide-major histocompatibility complex features limits repertoire diversity in virus-specific CD8+ T cell populations. Nat Immunol (2005) 2.44
Recognition of β-linked self glycolipids mediated by natural killer T cell antigen receptors. Nat Immunol (2011) 2.42
The structural basis of Janus kinase 2 inhibition by a potent and specific pan-Janus kinase inhibitor. Blood (2005) 2.41
The CDR3 regions of an immunodominant T cell receptor dictate the 'energetic landscape' of peptide-MHC recognition. Nat Immunol (2005) 2.38
Seven mutations in the human insulin gene linked to permanent neonatal/infancy-onset diabetes mellitus. J Clin Invest (2008) 2.36
Siah ubiquitin ligase is structurally related to TRAF and modulates TNF-alpha signaling. Nat Struct Biol (2002) 2.32
T cell allorecognition via molecular mimicry. Immunity (2009) 2.25
Do current therapeutic anti-Aβ antibodies for Alzheimer's disease engage the target? Acta Neuropathol (2014) 2.25
The 2.0-A crystal structure of eqFP611, a far red fluorescent protein from the sea anemone Entacmaea quadricolor. J Biol Chem (2003) 2.23
AMPK beta subunit targets metabolic stress sensing to glycogen. Curr Biol (2003) 2.19
Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin. Nature (2008) 2.11
A molecular basis for the exquisite CD1d-restricted antigen specificity and functional responses of natural killer T cells. Immunity (2011) 2.11
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Intravenous immunoglobulin versus intravenous methylprednisolone for chronic inflammatory demyelinating polyradiculoneuropathy: a randomised controlled trial. Lancet Neurol (2012) 1.95
Butyrophilin 3A1 binds phosphorylated antigens and stimulates human γδ T cells. Nat Immunol (2013) 1.95
Killer cell immunoglobulin-like receptor 3DL1-mediated recognition of human leukocyte antigen B. Nature (2011) 1.94
A molecular basis for NKT cell recognition of CD1d-self-antigen. Immunity (2011) 1.94
Human factor H-related protein 5 has cofactor activity, inhibits C3 convertase activity, binds heparin and C-reactive protein, and associates with lipoprotein. J Immunol (2005) 1.92
Comprehensive, quantitative mapping of T cell epitopes in gluten in celiac disease. Sci Transl Med (2010) 1.90
The fidelity, occasional promiscuity, and versatility of T cell receptor recognition. Immunity (2008) 1.89
Large-scale population analysis challenges the current criteria for the molecular diagnosis of fascioscapulohumeral muscular dystrophy. Am J Hum Genet (2012) 1.88
Adaptability of the semi-invariant natural killer T-cell receptor towards structurally diverse CD1d-restricted ligands. EMBO J (2009) 1.88
T cell receptor CDR2 beta and CDR3 beta loops collaborate functionally to shape the iNKT cell repertoire. Immunity (2009) 1.85
Model for growth hormone receptor activation based on subunit rotation within a receptor dimer. Nat Struct Mol Biol (2005) 1.83
Preexisting CD8+ T-cell immunity to the H7N9 influenza A virus varies across ethnicities. Proc Natl Acad Sci U S A (2014) 1.83
The structure of the GM-CSF receptor complex reveals a distinct mode of cytokine receptor activation. Cell (2008) 1.83
Alternative cross-priming through CCL17-CCR4-mediated attraction of CTLs toward NKT cell-licensed DCs. Nat Immunol (2010) 1.81
Comparison between the two systems to evaluate the appropriateness of endoscopy of the upper digestive tract. Am J Gastroenterol (2004) 1.79
Elucidation of the substrate binding site of Siah ubiquitin ligase. Structure (2006) 1.79
Germline missense mutations affecting KRAS Isoform B are associated with a severe Noonan syndrome phenotype. Am J Hum Genet (2006) 1.78
Human leukocyte antigen class I-restricted activation of CD8+ T cells provides the immunogenetic basis of a systemic drug hypersensitivity. Immunity (2008) 1.76
Anxiety over GABA(A) receptor structure relieved by AChBP. Trends Biochem Sci (2002) 1.74
Interferon-ε protects the female reproductive tract from viral and bacterial infection. Science (2013) 1.73
A naturally selected dimorphism within the HLA-B44 supertype alters class I structure, peptide repertoire, and T cell recognition. J Exp Med (2003) 1.72
Structural insight into MR1-mediated recognition of the mucosal associated invariant T cell receptor. J Exp Med (2012) 1.71
Critical role for the second extracellular loop in the binding of both orthosteric and allosteric G protein-coupled receptor ligands. J Biol Chem (2007) 1.70
A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis. J Exp Med (2013) 1.69
Autosomal recessive hypercholesterolaemia in Sardinia, Italy, and mutations in ARH: a clinical and molecular genetic analysis. Lancet (2002) 1.69
The granulocyte-macrophage colony-stimulating factor receptor: linking its structure to cell signaling and its role in disease. Blood (2009) 1.63
Cross-reactive CD8+ T-cell immunity between the pandemic H1N1-2009 and H1N1-1918 influenza A viruses. Proc Natl Acad Sci U S A (2010) 1.63
High resolution structures of highly bulged viral epitopes bound to major histocompatibility complex class I. Implications for T-cell receptor engagement and T-cell immunodominance. J Biol Chem (2005) 1.63
Molecular dissection of the interaction between amyloid precursor protein and its neuronal trafficking receptor SorLA/LR11. Biochemistry (2006) 1.63
Insights into the action of the superfamily of cholesterol-dependent cytolysins from studies of intermedilysin. Proc Natl Acad Sci U S A (2005) 1.63
Cytoplasmic ATP-sensing domains regulate gating of skeletal muscle ClC-1 chloride channels. J Biol Chem (2005) 1.62
Recognition of vitamin B metabolites by mucosal-associated invariant T cells. Nat Commun (2013) 1.61
The 2.2 A crystal structure of a pocilloporin pigment reveals a nonplanar chromophore conformation. Structure (2003) 1.61
The 1.5 A crystal structure of a prokaryote serpin: controlling conformational change in a heated environment. Structure (2003) 1.61
A minimal binding footprint on CD1d-glycolipid is a basis for selection of the unique human NKT TCR. J Exp Med (2008) 1.60
Hard wiring of T cell receptor specificity for the major histocompatibility complex is underpinned by TCR adaptability. Proc Natl Acad Sci U S A (2010) 1.60
Effects of folic acid before and after vitamin B12 on plasma homocysteine concentrations in hemodialysis patients with known MTHFR genotypes. Clin Chem (2006) 1.60
Structure, biological functions and applications of the AB5 toxins. Trends Biochem Sci (2010) 1.57
GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop. Nat Struct Mol Biol (2007) 1.56
A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition. J Exp Med (2006) 1.56
The insulin A-chain epitope recognized by human T cells is posttranslationally modified. J Exp Med (2005) 1.55
Structures of perfringolysin O suggest a pathway for activation of cholesterol-dependent cytolysins. J Mol Biol (2007) 1.54
Antigen recognition by CD1d-restricted NKT T cell receptors. Semin Immunol (2009) 1.53
Structural basis for glycogen recognition by AMP-activated protein kinase. Structure (2005) 1.50
A conserved human T cell population targets mycobacterial antigens presented by CD1b. Nat Immunol (2013) 1.49
T-cell receptor bias and immunity. Curr Opin Immunol (2008) 1.47
A semi-invariant Vα10+ T cell antigen receptor defines a population of natural killer T cells with distinct glycolipid antigen-recognition properties. Nat Immunol (2011) 1.47
A structural and immunological basis for the role of human leukocyte antigen DQ8 in celiac disease. Immunity (2007) 1.46
EcxAB is a founding member of a new family of metalloprotease AB5 toxins with a hybrid cholera-like B subunit. Structure (2013) 1.46
An activation-specific platelet inhibitor that can be turned on/off by medically used hypothermia. Arterioscler Thromb Vasc Biol (2011) 1.46
Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes. Nat Immunol (2012) 1.46
Natural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognition. J Exp Med (2009) 1.45
Rowe and Kahn's model of successful aging revisited: positive spirituality--the forgotten factor. Gerontologist (2002) 1.44
LIMPIC: a computational method for the separation of protein MALDI-TOF-MS signals from noise. BMC Bioinformatics (2007) 1.44
Recognition of CD1d-sulfatide mediated by a type II natural killer T cell antigen receptor. Nat Immunol (2012) 1.44
Natural HLA class I polymorphism controls the pathway of antigen presentation and susceptibility to viral evasion. J Exp Med (2004) 1.43
Quantitative analysis of bile acids in human plasma by liquid chromatography-electrospray tandem mass spectrometry: a simple and rapid one-step method. Clin Chem Lab Med (2003) 1.43
Intrasteric control of AMPK via the gamma1 subunit AMP allosteric regulatory site. Protein Sci (2004) 1.41
Distinct cytokine patterns associated with different forms of chronic dysimmune neuropathy. Muscle Nerve (2010) 1.41
Structural basis of a unique interferon-β signaling axis mediated via the receptor IFNAR1. Nat Immunol (2013) 1.41
A molecular basis for the control of preimmune escape variants by HIV-specific CD8+ T cells. Immunity (2013) 1.41
Have we cut ourselves too short in mapping CTL epitopes? Trends Immunol (2005) 1.41
Oseltamivir resistance and the H274Y neuraminidase mutation in seasonal, pandemic and highly pathogenic influenza viruses. Drugs (2009) 1.41
Antigen ligation triggers a conformational change within the constant domain of the alphabeta T cell receptor. Immunity (2009) 1.40