Published in Biophys J on February 01, 2003
Phospholipase C in living cells: activation, inhibition, Ca2+ requirement, and regulation of M current. J Gen Physiol (2005) 2.98
Intracellular macromolecular mobility measured by fluorescence recovery after photobleaching with confocal laser scanning microscopes. Mol Biol Cell (2004) 2.10
Control of eIF4E cellular localization by eIF4E-binding proteins, 4E-BPs. RNA (2008) 1.69
Development of a novel GFP-based ratiometric excitation and emission pH indicator for intracellular studies. Biophys J (2006) 1.43
In vivo imaging of single-molecule translocation through nuclear pore complexes by pair correlation functions. PLoS One (2010) 1.38
Mapping eGFP oligomer mobility in living cell nuclei. PLoS One (2009) 1.34
Nucleocytoplasmic distribution and dynamics of the autophagosome marker EGFP-LC3. PLoS One (2010) 1.28
A reaction-diffusion model to study RNA motion by quantitative fluorescence recovery after photobleaching. Biophys J (2007) 1.27
Integrase interacts with nucleoporin NUP153 to mediate the nuclear import of human immunodeficiency virus type 1. J Virol (2009) 1.26
Glyceraldehyde 3-phosphate dehydrogenase depletion induces cell cycle arrest and resistance to antimetabolites in human carcinoma cell lines. J Pharmacol Exp Ther (2009) 1.02
Development of transgenic rats producing human beta-amyloid precursor protein as a model for Alzheimer's disease: transgene and endogenous APP genes are regulated tissue-specifically. BMC Neurosci (2008) 0.94
Diffusion of large molecules into assembling nuclei revealed using an optical highlighting technique. Biophys J (2009) 0.93
Nuclear location of tumor suppressor protein maspin inhibits proliferation of breast cancer cells without affecting proliferation of normal epithelial cells. BMC Cancer (2014) 0.92
Formation of the nuclear envelope permeability barrier studied by sequential photoswitching and flux analysis. Biophys J (2009) 0.92
Signaling from the secretory granule to the nucleus: Uhmk1 and PAM. Mol Endocrinol (2010) 0.92
Continuous photobleaching in vesicles and living cells: a measure of diffusion and compartmentation. Biophys J (2006) 0.90
Visualization of plasmid delivery to keratinocytes in mouse and human epidermis. Sci Rep (2011) 0.89
Hormonal regulation of nuclear permeability. J Biol Chem (2006) 0.88
Size-dependent leak of soluble and membrane proteins through the yeast nuclear pore complex. Mol Biol Cell (2015) 0.86
Quantitative fluorescence loss in photobleaching for analysis of protein transport and aggregation. BMC Bioinformatics (2012) 0.85
Functional impact of ZEB1 mutations associated with posterior polymorphous and Fuchs' endothelial corneal dystrophies. Invest Ophthalmol Vis Sci (2014) 0.85
Caspase-8 cleaves its substrates from the plasma membrane upon CD95-induced apoptosis. Cell Death Differ (2013) 0.83
A simple kinetic model with explicit predictions for nuclear transport. Biophys J (2013) 0.81
Regeneration of mammalian cochlear and vestibular hair cells through Hes1/Hes5 modulation with siRNA. Hear Res (2013) 0.79
Calcium regulation of nucleocytoplasmic transport. Protein Cell (2011) 0.79
Single- and two-photon fluorescence recovery after photobleaching. Cold Spring Harb Protoc (2015) 0.78
Regulation of nuclear envelope permeability in cell death and survival. Nucleus (2012) 0.77
Nuclear LC3 Associates with Slowly Diffusing Complexes that Survey the Nucleolus. Traffic (2016) 0.77
Expression of the HSF4 DNA binding domain-EGFP hybrid gene recreates early childhood lamellar cataract in transgenic mice. Invest Ophthalmol Vis Sci (2014) 0.75
Time-resolved biophysical approaches to nucleocytoplasmic transport. Comput Struct Biotechnol J (2017) 0.75
A murine Zic3 transcript with a premature termination codon evades nonsense-mediated decay during axis formation. Dis Model Mech (2013) 0.75
The green fluorescent protein. Annu Rev Biochem (1998) 34.17
Mobility measurement by analysis of fluorescence photobleaching recovery kinetics. Biophys J (1976) 25.12
A simplified system for generating recombinant adenoviruses. Proc Natl Acad Sci U S A (1998) 24.58
Fluorescent indicators for Ca2+ based on green fluorescent proteins and calmodulin. Nature (1997) 18.83
Crystal structure of the Aequorea victoria green fluorescent protein. Science (1996) 16.81
The molecular structure of green fluorescent protein. Nat Biotechnol (1996) 9.63
Nuclear membrane dynamics and reassembly in living cells: targeting of an inner nuclear membrane protein in interphase and mitosis. J Cell Biol (1997) 6.57
Movement of a karyophilic protein through the nuclear pores of oocytes. J Cell Biol (1984) 6.51
Use of the green fluorescent protein and its mutants in quantitative fluorescence microscopy. Biophys J (1997) 6.26
Functional organization of the nuclear envelope. Annu Rev Cell Biol (1988) 5.80
Kinetic analysis of translocation through nuclear pore complexes. EMBO J (2001) 5.27
Translational diffusion of macromolecule-sized solutes in cytoplasm and nucleus. J Cell Biol (1997) 4.53
Direct measurement of coupling between dendritic spines and shafts. Science (1996) 3.98
Integral membrane proteins of the nuclear envelope interact with lamins and chromosomes, and binding is modulated by mitotic phosphorylation. Cell (1993) 3.77
Anomalous diffusion of fluorescent probes inside living cell nuclei investigated by spatially-resolved fluorescence correlation spectroscopy. J Mol Biol (2000) 3.65
Facilitated nuclear transport of histone H1 and other small nucleophilic proteins. Cell (1990) 3.28
Spatial dynamics of GFP-tagged proteins investigated by local fluorescence enhancement. Nat Biotechnol (1996) 3.19
Photobleaching GFP reveals protein dynamics inside live cells. Trends Cell Biol (1999) 2.86
Protein import into the nucleus: an integrated view. Annu Rev Cell Dev Biol (1995) 2.75
Evidence for localized cell heating induced by infrared optical tweezers. Biophys J (1995) 2.57
The nuclear pore complex: mediator of translocation between nucleus and cytoplasm. J Cell Sci (2000) 2.50
Ribonucleotide reductase--a radical enzyme. Science (1983) 2.33
Permeability of single nuclear pores. Biophys J (1999) 2.25
Gatekeepers of the nucleus. Science (2000) 2.12
Mechanisms of calcium decay kinetics in hippocampal spines: role of spine calcium pumps and calcium diffusion through the spine neck in biochemical compartmentalization. J Neurosci (2000) 2.09
The permeability of the nuclear envelope in dividing and nondividing cell cultures. J Cell Biol (1990) 2.06
Graded ATP depletion can cause necrosis or apoptosis of cultured mouse proximal tubular cells. Am J Physiol (1998) 1.80
Chromatin-independent nuclear envelope assembly induced by Ran GTPase in Xenopus egg extracts. Science (2000) 1.61
Diffusion across the nuclear envelope inhibited by depletion of the nuclear Ca2+ store. Science (1995) 1.56
Depletion of calcium from the lumen of endoplasmic reticulum reversibly inhibits passive diffusion and signal-mediated transport into the nucleus. J Cell Biol (1995) 1.55
Cell synchronization. Methods Enzymol (1995) 1.54
Conformational states of the nuclear pore complex induced by depletion of nuclear Ca2+ stores. Science (1996) 1.50
Perturbations in maturation of secretory proteins and their association with endoplasmic reticulum chaperones in a cell culture model for epithelial ischemia. Proc Natl Acad Sci U S A (1996) 1.46
Nuclear reassembly excludes large macromolecules. Science (1987) 1.39
Calcium-mediated structural changes of native nuclear pore complexes monitored by time-lapse atomic force microscopy. J Mol Biol (1999) 1.33
Stress, apoptosis, and mitosis induce phosphorylation of human keratin 8 at Ser-73 in tissues and cultured cells. J Biol Chem (1997) 1.27
Structural plasticity of the cardiac nuclear pore complex in response to regulators of nuclear import. Circ Res (1999) 1.07
Active nuclear import and export is independent of lumenal Ca2+ stores in intact mammalian cells. J Gen Physiol (1999) 1.05
Conformational changes of the in situ nuclear pore complex. Biophys J (1999) 1.02
Evidence for Ca2+- and ATP-sensitive peripheral channels in nuclear pore complexes. FASEB J (2001) 0.97
Rho controls actin cytoskeletal assembly in renal epithelial cells during ATP depletion and recovery. Am J Physiol (1999) 0.94
Nuclear pore function viewed with atomic force microscopy. Pflugers Arch (2000) 0.92
Mitosis. Bioessays (1994) 0.90
Fluorescence redistribution after photobleaching as a tool for dissecting the control elements of nucleocytoplasmic transport. Methods Enzymol (1987) 0.87
Nuclear protein transport pathways. Exp Nephrol (1999) 0.84
Cell cycle control of PDGF-induced Ca(2+) signaling through modulation of sphingolipid metabolism. FASEB J (1999) 0.82
An introduction to TRP channels. Annu Rev Physiol (2006) 7.52
The mitochondrial calcium uniporter is a highly selective ion channel. Nature (2004) 6.97
TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function. Nat Genet (2005) 5.53
Lymphatic metastasis in the absence of functional intratumor lymphatics. Science (2002) 5.32
Developmental origin of a bipotential myocardial and smooth muscle cell precursor in the mammalian heart. Cell (2006) 5.03
A voltage-gated proton-selective channel lacking the pore domain. Nature (2006) 4.89
Rapid vesicular translocation and insertion of TRP channels. Nat Cell Biol (2004) 4.19
Genome-wide RNAi screen identifies Letm1 as a mitochondrial Ca2+/H+ antiporter. Science (2009) 3.96
The TRPM7 channel is inactivated by PIP(2) hydrolysis. Nat Cell Biol (2002) 3.63
TRPV3 is a calcium-permeable temperature-sensitive cation channel. Nature (2002) 3.55
Diffusion and convection in collagen gels: implications for transport in the tumor interstitium. Biophys J (2002) 3.25
Quantum dots spectrally distinguish multiple species within the tumor milieu in vivo. Nat Med (2005) 3.19
A unified nomenclature for the superfamily of TRP cation channels. Mol Cell (2002) 2.99
Crystal structure of an orthologue of the NaChBac voltage-gated sodium channel. Nature (2012) 2.97
International Union of Basic and Clinical Pharmacology. LXXVI. Current progress in the mammalian TRP ion channel family. Pharmacol Rev (2010) 2.66
Whole-cell patch-clamp measurements of spermatozoa reveal an alkaline-activated Ca2+ channel. Nature (2006) 2.63
The NMDA receptor is coupled to the ERK pathway by a direct interaction between NR2B and RasGRF1. Neuron (2003) 2.61
Deletion of Trpm7 disrupts embryonic development and thymopoiesis without altering Mg2+ homeostasis. Science (2008) 2.59
All four CatSper ion channel proteins are required for male fertility and sperm cell hyperactivated motility. Proc Natl Acad Sci U S A (2007) 2.59
Oregano, thyme and clove-derived flavors and skin sensitizers activate specific TRP channels. Nat Neurosci (2006) 2.58
Mitochondrial membrane potential probes and the proton gradient: a practical usage guide. Biotechniques (2011) 2.51
The TRPM7 ion channel functions in cholinergic synaptic vesicles and affects transmitter release. Neuron (2006) 2.50
Phosphatidylinositol 3-kinase activates ERK in primary sensory neurons and mediates inflammatory heat hyperalgesia through TRPV1 sensitization. J Neurosci (2004) 2.41
Functional TRPM7 channels accumulate at the plasma membrane in response to fluid flow. Circ Res (2005) 2.40
EMRE is an essential component of the mitochondrial calcium uniporter complex. Science (2013) 2.39
TPC proteins are phosphoinositide- activated sodium-selective ion channels in endosomes and lysosomes. Cell (2012) 2.35
CatSper1 required for evoked Ca2+ entry and control of flagellar function in sperm. Proc Natl Acad Sci U S A (2003) 2.34
TRP channel regulates EGFR signaling in hair morphogenesis and skin barrier formation. Cell (2010) 2.32
Formation of novel TRPC channels by complex subunit interactions in embryonic brain. J Biol Chem (2003) 2.29
Cationic charge determines the distribution of liposomes between the vascular and extravascular compartments of tumors. Cancer Res (2002) 2.09
Camphor activates and strongly desensitizes the transient receptor potential vanilloid subtype 1 channel in a vanilloid-independent mechanism. J Neurosci (2005) 2.09
International Union of Pharmacology. XLI. Compendium of voltage-gated ion channels: potassium channels. Pharmacol Rev (2003) 2.05
TRPV4 is a regulator of adipose oxidative metabolism, inflammation, and energy homeostasis. Cell (2012) 2.03
Activating mutation in a mucolipin transient receptor potential channel leads to melanocyte loss in varitint-waddler mice. Proc Natl Acad Sci U S A (2007) 1.99
SynGAP-MUPP1-CaMKII synaptic complexes regulate p38 MAP kinase activity and NMDA receptor-dependent synaptic AMPA receptor potentiation. Neuron (2004) 1.97
TRPC5 is a regulator of hippocampal neurite length and growth cone morphology. Nat Neurosci (2003) 1.95
The cation selectivity filter of the bacterial sodium channel, NaChBac. J Gen Physiol (2002) 1.94
A superfamily of voltage-gated sodium channels in bacteria. J Biol Chem (2003) 1.84
Hv1 proton channels are required for high-level NADPH oxidase-dependent superoxide production during the phagocyte respiratory burst. Proc Natl Acad Sci U S A (2009) 1.80
TRP ion channels in the nervous system. Curr Opin Neurobiol (2004) 1.78
Differential transplantability of tumor-associated stromal cells. Cancer Res (2004) 1.78
KSper, a pH-sensitive K+ current that controls sperm membrane potential. Proc Natl Acad Sci U S A (2007) 1.77
TRPM1 forms ion channels associated with melanin content in melanocytes. Sci Signal (2009) 1.75
The control of male fertility by spermatozoan ion channels. Annu Rev Physiol (2011) 1.74
Essential role for TRPC5 in amygdala function and fear-related behavior. Cell (2009) 1.72
International Union of Pharmacology. LIV. Nomenclature and molecular relationships of inwardly rectifying potassium channels. Pharmacol Rev (2005) 1.63
Mammalian MagT1 and TUSC3 are required for cellular magnesium uptake and vertebrate embryonic development. Proc Natl Acad Sci U S A (2009) 1.60
Intracellular calcium strongly potentiates agonist-activated TRPC5 channels. J Gen Physiol (2009) 1.51
Rheotaxis guides mammalian sperm. Curr Biol (2013) 1.47
Two-photon fluorescence correlation microscopy reveals the two-phase nature of transport in tumors. Nat Med (2004) 1.45
The voltage-gated proton channel Hv1 enhances brain damage from ischemic stroke. Nat Neurosci (2012) 1.45
CatSperbeta, a novel transmembrane protein in the CatSper channel complex. J Biol Chem (2007) 1.43
Second harmonic properties of tumor collagen: determining the structural relationship between reactive stroma and healthy stroma. Opt Express (2008) 1.40
MCU encodes the pore conducting mitochondrial calcium currents. Elife (2013) 1.39
CACNA1H mutations in autism spectrum disorders. J Biol Chem (2006) 1.35
Red blood cells augment leukocyte rolling in a virtual blood vessel. Biophys J (2002) 1.31
The channel kinase, TRPM7, is required for early embryonic development. Proc Natl Acad Sci U S A (2011) 1.29
The voltage-gated Na+ channel NaVBP has a role in motility, chemotaxis, and pH homeostasis of an alkaliphilic Bacillus. Proc Natl Acad Sci U S A (2004) 1.28
Phenotyping sensory nerve endings in vitro in the mouse. Nat Protoc (2009) 1.27
A spontaneous, recurrent mutation in divalent metal transporter-1 exposes a calcium entry pathway. PLoS Biol (2004) 1.26
Molecular dynamics of ion transport through the open conformation of a bacterial voltage-gated sodium channel. Proc Natl Acad Sci U S A (2013) 1.25
Calbindin-D28K dynamically controls TRPV5-mediated Ca2+ transport. EMBO J (2006) 1.25
Ion channels that control fertility in mammalian spermatozoa. Int J Dev Biol (2008) 1.23
Transient receptor potential cation channel, subfamily C, member 5 (TRPC5) is a cold-transducer in the peripheral nervous system. Proc Natl Acad Sci U S A (2011) 1.19
Role of the C-terminal domain in the structure and function of tetrameric sodium channels. Nat Commun (2013) 1.19
TRPM7 facilitates cholinergic vesicle fusion with the plasma membrane. Proc Natl Acad Sci U S A (2008) 1.17
Diffusional mobility of parvalbumin in spiny dendrites of cerebellar Purkinje neurons quantified by fluorescence recovery after photobleaching. Biophys J (2003) 1.17
A novel gene required for male fertility and functional CATSPER channel formation in spermatozoa. Nat Commun (2011) 1.16
Mechanism of persistent protein kinase D1 translocation and activation. Dev Cell (2003) 1.15
Bisandrographolide from Andrographis paniculata activates TRPV4 channels. J Biol Chem (2006) 1.14
Multiscale measurements distinguish cellular and interstitial hindrances to diffusion in vivo. Biophys J (2009) 1.12
POST, partner of stromal interaction molecule 1 (STIM1), targets STIM1 to multiple transporters. Proc Natl Acad Sci U S A (2011) 1.12
Ancestral Ca2+ signaling machinery in early animal and fungal evolution. Mol Biol Evol (2011) 1.12
Letm1, the mitochondrial Ca2+/H+ antiporter, is essential for normal glucose metabolism and alters brain function in Wolf-Hirschhorn syndrome. Proc Natl Acad Sci U S A (2013) 1.10
Improved model of fluorescence recovery expands the application of multiphoton fluorescence recovery after photobleaching in vivo. Biophys J (2009) 1.10
TATA-binding protein (TBP)-like factor (TLF) is a functional regulator of transcription: reciprocal regulation of the neurofibromatosis type 1 and c-fos genes by TLF/TRF2 and TBP. Mol Cell Biol (2005) 1.07
Cleavage of TRPM7 releases the kinase domain from the ion channel and regulates its participation in Fas-induced apoptosis. Dev Cell (2012) 1.07
β-Adrenergic receptors (β-AR) regulate VEGF and IL-6 production by divergent pathways in high β-AR-expressing breast cancer cell lines. Breast Cancer Res Treat (2011) 1.06
Evolutionary genomics reveals lineage-specific gene loss and rapid evolution of a sperm-specific ion channel complex: CatSpers and CatSperbeta. PLoS One (2008) 1.05
Two-photon and second harmonic microscopy in clinical and translational cancer research. Ann Biomed Eng (2012) 1.01
Citral sensing by Transient [corrected] receptor potential channels in dorsal root ganglion neurons. PLoS One (2008) 1.01
TRP channels and mice deficient in TRP channels. Pflugers Arch (2005) 1.00
Targeted cytosolic delivery of cell-impermeable compounds by nanoparticle-mediated, light-triggered endosome disruption. Nano Lett (2010) 0.99
TRPM7, the Mg(2+) inhibited channel and kinase. Adv Exp Med Biol (2011) 0.99
The G-protein-gated K+ channel, IKACh, is required for regulation of pacemaker activity and recovery of resting heart rate after sympathetic stimulation. J Gen Physiol (2013) 0.97
Timing of myocardial trpm7 deletion during cardiogenesis variably disrupts adult ventricular function, conduction, and repolarization. Circulation (2013) 0.97
The phospholipid-binding protein SESTD1 is a novel regulator of the transient receptor potential channels TRPC4 and TRPC5. J Biol Chem (2010) 0.94
Controlled delivery of bioactive molecules into live cells using the bacterial mechanosensitive channel MscL. Nat Commun (2012) 0.93
Parvalbumin is freely mobile in axons, somata and nuclei of cerebellar Purkinje neurones. J Neurochem (2007) 0.93
In vivo quantification of lymph viscosity and pressure in lymphatic vessels and draining lymph nodes of arthritic joints in mice. J Physiol (2014) 0.93
Ion channel-kinase TRPM7 is required for maintaining cardiac automaticity. Proc Natl Acad Sci U S A (2013) 0.92
Analysis of the selectivity filter of the voltage-gated sodium channel Na(v)Rh. Cell Res (2012) 0.92
Simultaneous knockout of Slo3 and CatSper1 abolishes all alkalization- and voltage-activated current in mouse spermatozoa. J Gen Physiol (2013) 0.92
A STIMulus Package puts orai calcium channels to work. Cell (2009) 0.91
ATP-activated P2X2 current in mouse spermatozoa. Proc Natl Acad Sci U S A (2011) 0.91
Stromal matrix metalloprotease-13 knockout alters Collagen I structure at the tumor-host interface and increases lung metastasis of C57BL/6 syngeneic E0771 mammary tumor cells. BMC Cancer (2013) 0.91
Automated tracing and change analysis of angiogenic vasculature from in vivo multiphoton confocal image time series. Microvasc Res (2003) 0.90
Anion-sensitive fluorophore identifies the Drosophila swell-activated chloride channel in a genome-wide RNA interference screen. PLoS One (2012) 0.90
Calpain cleaves and activates the TRPC5 channel to participate in semaphorin 3A-induced neuronal growth cone collapse. Proc Natl Acad Sci U S A (2012) 0.89