Published in Circ Res on December 15, 2005
TRP channels. Annu Rev Biochem (2007) 8.09
The functional network of ion channels in T lymphocytes. Immunol Rev (2009) 3.21
International Union of Basic and Clinical Pharmacology. LXXVI. Current progress in the mammalian TRP ion channel family. Pharmacol Rev (2010) 2.66
Oncosome formation in prostate cancer: association with a region of frequent chromosomal deletion in metastatic disease. Cancer Res (2009) 2.07
Arterial response to shear stress critically depends on endothelial TRPV4 expression. PLoS One (2007) 1.79
TRPM1 forms ion channels associated with melanin content in melanocytes. Sci Signal (2009) 1.75
TRPM7-mediated Ca2+ signals confer fibrogenesis in human atrial fibrillation. Circ Res (2010) 1.65
Molecular mechanism of TRP channels. Compr Physiol (2013) 1.58
TRPM2: a multifunctional ion channel for calcium signalling. J Physiol (2010) 1.51
Nicotine up-regulates alpha4beta2 nicotinic receptors and ER exit sites via stoichiometry-dependent chaperoning. J Gen Physiol (2011) 1.46
Rapid and Localized Mechanical Stimulation and Adhesion Assay: TRPM7 Involvement in Calcium Signaling and Cell Adhesion. PLoS One (2015) 1.41
Functional characterization of transient receptor potential channels in mouse urothelial cells. Am J Physiol Renal Physiol (2009) 1.39
Fluid flow mechanotransduction in vascular smooth muscle cells and fibroblasts. Ann Biomed Eng (2011) 1.32
TRP channels of intracellular membranes. J Neurochem (2010) 1.30
Expression and distribution of transient receptor potential (TRP) channels in bladder epithelium. Am J Physiol Renal Physiol (2010) 1.27
TRP channels and mechanosensory transduction: insights into the arterial myogenic response. Pflugers Arch (2008) 1.24
TRPM7 facilitates cholinergic vesicle fusion with the plasma membrane. Proc Natl Acad Sci U S A (2008) 1.17
The alpha-kinase family: an exceptional branch on the protein kinase tree. Cell Mol Life Sci (2009) 1.16
Silencing TRPM7 promotes growth/proliferation and nitric oxide production of vascular endothelial cells via the ERK pathway. Cardiovasc Res (2009) 1.16
TRPM6 and TRPM7: A Mul-TRP-PLIK-cation of channel functions. Curr Pharm Biotechnol (2011) 1.14
Vasoconstriction resulting from dynamic membrane trafficking of TRPM4 in vascular smooth muscle cells. Am J Physiol Cell Physiol (2010) 1.09
Calpain 2 controls turnover of LFA-1 adhesions on migrating T lymphocytes. PLoS One (2010) 1.08
TRPM7 activates m-calpain by stress-dependent stimulation of p38 MAPK and c-Jun N-terminal kinase. J Mol Biol (2010) 1.07
Dependence of regulatory volume decrease on transient receptor potential vanilloid 4 (TRPV4) expression in human corneal epithelial cells. Cell Calcium (2008) 1.05
Near-membrane dynamics and capture of TRPM8 channels within transient confinement domains. PLoS One (2010) 1.02
Blockade of TRPM7 channel activity and cell death by inhibitors of 5-lipoxygenase. PLoS One (2010) 1.01
Upregulation of osmo-mechanosensitive TRPV4 channel facilitates chronic hypoxia-induced myogenic tone and pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol (2011) 1.01
Transient receptor potential channel activation and endothelium-dependent dilation in the systemic circulation. J Cardiovasc Pharmacol (2011) 1.01
Natural and synthetic modulators of SK (K(ca)2) potassium channels inhibit magnesium-dependent activity of the kinase-coupled cation channel TRPM7. Br J Pharmacol (2012) 1.01
Regulation and function of TRPM7 in human endothelial cells: TRPM7 as a potential novel regulator of endothelial function. PLoS One (2013) 1.00
TRPM7 and TRPM2-Candidate susceptibility genes for Western Pacific ALS and PD? Biochim Biophys Acta (2007) 1.00
Fluid Mechanics, Arterial Disease, and Gene Expression. Annu Rev Fluid Mech (2014) 1.00
Extracellular pH dynamically controls cell surface delivery of functional TRPV5 channels. Mol Cell Biol (2006) 0.98
Proton-sensitive cation channels and ion exchangers in ischemic brain injury: new therapeutic targets for stroke? Prog Neurobiol (2014) 0.96
Molecular and electrophysiological characterization of transient receptor potential ion channels in the primary murine megakaryocyte. J Physiol (2006) 0.96
Two distinct phases of calcium signalling under flow. Cardiovasc Res (2011) 0.94
Characterizing functional α6β2 nicotinic acetylcholine receptors in vitro: mutant β2 subunits improve membrane expression, and fluorescent proteins reveal responsive cells. Biochem Pharmacol (2011) 0.93
TRPM7 channel is sensitive to osmotic gradients in human kidney cells. J Physiol (2007) 0.93
Evidence for functional expression of TRPM7 channels in human atrial myocytes. Basic Res Cardiol (2012) 0.92
Distinct modes of perimembrane TRP channel turnover revealed by TIR-FRAP. Sci Rep (2014) 0.91
Update on vascular endothelial Ca(2+) signalling: A tale of ion channels, pumps and transporters. World J Biol Chem (2012) 0.91
Cellular and Developmental Biology of TRPM7 Channel-Kinase: Implicated Roles in Cancer. Cells (2014) 0.89
Role of TRP channels in the cardiovascular system. Am J Physiol Heart Circ Physiol (2014) 0.88
TRPM7 triggers Ca2+ sparks and invadosome formation in neuroblastoma cells. Cell Calcium (2013) 0.88
Shear stress triggers insertion of voltage-gated potassium channels from intracellular compartments in atrial myocytes. Proc Natl Acad Sci U S A (2013) 0.87
Role of TRPM7 channels in hyperglycemia-mediated injury of vascular endothelial cells. PLoS One (2013) 0.87
Activation of TRPM7 channels by small molecules under physiological conditions. Pflugers Arch (2014) 0.87
Flow shear stress enhances intracellular Ca2+ signaling in pulmonary artery smooth muscle cells from patients with pulmonary arterial hypertension. Am J Physiol Cell Physiol (2014) 0.85
Pharmacology of transient receptor potential melastatin channels in the vasculature. Br J Pharmacol (2010) 0.85
Live cell imaging of mechanotransduction. J R Soc Interface (2010) 0.83
TRPM7 in cerebral ischemia and potential target for drug development in stroke. Acta Pharmacol Sin (2011) 0.83
Astrocytes in the optic nerve head express putative mechanosensitive channels. Mol Vis (2015) 0.83
Mechanosensitive TRPM7 mediates shear stress and modulates osteogenic differentiation of mesenchymal stromal cells through Osterix pathway. Sci Rep (2015) 0.82
The sodium-calcium exchanger is a mechanosensitive transporter. J Physiol (2008) 0.82
G protein-coupled receptor signalling potentiates the osmo-mechanical activation of TRPC5 channels. Pflugers Arch (2013) 0.81
TRPM7 maintains progenitor-like features of neuroblastoma cells: implications for metastasis formation. Oncotarget (2015) 0.80
Transcriptional remodeling of ion channel subunits by flow adaptation in human coronary artery endothelial cells. J Vasc Res (2011) 0.80
Natural and Synthetic Modulators of the TRPM7 Channel. Cells (2014) 0.80
Mechanochemical regulation of growth cone motility. Front Cell Neurosci (2015) 0.80
TR(I)Pping towards treatment for ischemia. Nat Neurosci (2009) 0.78
Transient Receptor Potential Melastatin 7 Cation Channel Kinase: New Player in Angiotensin II-Induced Hypertension. Hypertension (2016) 0.77
TRPM7, the cytoskeleton and neuronal death. Channels (Austin) (2012) 0.77
TRP Channels Localize to Subdomains of the Apical Plasma Membrane in Human Fetal Retinal Pigment Epithelium. Invest Ophthalmol Vis Sci (2015) 0.77
Aberrant over-expression of TRPM7 ion channels in pancreatic cancer: required for cancer cell invasion and implicated in tumor growth and metastasis. Biol Open (2015) 0.76
Going with the flow: smooth muscle TRPM7 channels and the vascular response to blood flow. Circ Res (2006) 0.76
SWELL1 is a regulator of adipocyte size, insulin signalling and glucose homeostasis. Nat Cell Biol (2017) 0.75
Mibefradil represents a new class of benzimidazole TRPM7 channel agonists. Pflugers Arch (2015) 0.75
MycN promotes TRPM7 expression and cell migration in neuroblastoma through a process that involves polyamines. FEBS Open Bio (2014) 0.75
Role of TRPM7 in Cerebral Ischaemia and Hypoxia. J Physiol (2016) 0.75
TRPM7 senses oxidative stress to release Zn(2+) from unique intracellular vesicles. Proc Natl Acad Sci U S A (2017) 0.75
Calcium Channels in Vascular Smooth Muscle. Adv Pharmacol (2016) 0.75
An introduction to TRP channels. Annu Rev Physiol (2006) 7.52
The mitochondrial calcium uniporter is a highly selective ion channel. Nature (2004) 6.97
TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function. Nat Genet (2005) 5.53
Developmental origin of a bipotential myocardial and smooth muscle cell precursor in the mammalian heart. Cell (2006) 5.03
A voltage-gated proton-selective channel lacking the pore domain. Nature (2006) 4.89
Rapid vesicular translocation and insertion of TRP channels. Nat Cell Biol (2004) 4.19
Genome-wide RNAi screen identifies Letm1 as a mitochondrial Ca2+/H+ antiporter. Science (2009) 3.96
The TRPM7 channel is inactivated by PIP(2) hydrolysis. Nat Cell Biol (2002) 3.63
TRPV3 is a calcium-permeable temperature-sensitive cation channel. Nature (2002) 3.55
A unified nomenclature for the superfamily of TRP cation channels. Mol Cell (2002) 2.99
Crystal structure of an orthologue of the NaChBac voltage-gated sodium channel. Nature (2012) 2.97
International Union of Basic and Clinical Pharmacology. LXXVI. Current progress in the mammalian TRP ion channel family. Pharmacol Rev (2010) 2.66
Whole-cell patch-clamp measurements of spermatozoa reveal an alkaline-activated Ca2+ channel. Nature (2006) 2.63
The NMDA receptor is coupled to the ERK pathway by a direct interaction between NR2B and RasGRF1. Neuron (2003) 2.61
Deletion of Trpm7 disrupts embryonic development and thymopoiesis without altering Mg2+ homeostasis. Science (2008) 2.59
All four CatSper ion channel proteins are required for male fertility and sperm cell hyperactivated motility. Proc Natl Acad Sci U S A (2007) 2.59
Oregano, thyme and clove-derived flavors and skin sensitizers activate specific TRP channels. Nat Neurosci (2006) 2.58
The TRPM7 ion channel functions in cholinergic synaptic vesicles and affects transmitter release. Neuron (2006) 2.50
Phosphatidylinositol 3-kinase activates ERK in primary sensory neurons and mediates inflammatory heat hyperalgesia through TRPV1 sensitization. J Neurosci (2004) 2.41
EMRE is an essential component of the mitochondrial calcium uniporter complex. Science (2013) 2.39
TPC proteins are phosphoinositide- activated sodium-selective ion channels in endosomes and lysosomes. Cell (2012) 2.35
CatSper1 required for evoked Ca2+ entry and control of flagellar function in sperm. Proc Natl Acad Sci U S A (2003) 2.34
TRP channel regulates EGFR signaling in hair morphogenesis and skin barrier formation. Cell (2010) 2.32
Formation of novel TRPC channels by complex subunit interactions in embryonic brain. J Biol Chem (2003) 2.29
Camphor activates and strongly desensitizes the transient receptor potential vanilloid subtype 1 channel in a vanilloid-independent mechanism. J Neurosci (2005) 2.09
International Union of Pharmacology. XLI. Compendium of voltage-gated ion channels: potassium channels. Pharmacol Rev (2003) 2.05
TRPV4 is a regulator of adipose oxidative metabolism, inflammation, and energy homeostasis. Cell (2012) 2.03
Activating mutation in a mucolipin transient receptor potential channel leads to melanocyte loss in varitint-waddler mice. Proc Natl Acad Sci U S A (2007) 1.99
SynGAP-MUPP1-CaMKII synaptic complexes regulate p38 MAP kinase activity and NMDA receptor-dependent synaptic AMPA receptor potentiation. Neuron (2004) 1.97
TRPC5 is a regulator of hippocampal neurite length and growth cone morphology. Nat Neurosci (2003) 1.95
The cation selectivity filter of the bacterial sodium channel, NaChBac. J Gen Physiol (2002) 1.94
A superfamily of voltage-gated sodium channels in bacteria. J Biol Chem (2003) 1.84
Hv1 proton channels are required for high-level NADPH oxidase-dependent superoxide production during the phagocyte respiratory burst. Proc Natl Acad Sci U S A (2009) 1.80
TRP ion channels in the nervous system. Curr Opin Neurobiol (2004) 1.78
KSper, a pH-sensitive K+ current that controls sperm membrane potential. Proc Natl Acad Sci U S A (2007) 1.77
TRPM1 forms ion channels associated with melanin content in melanocytes. Sci Signal (2009) 1.75
The control of male fertility by spermatozoan ion channels. Annu Rev Physiol (2011) 1.74
Essential role for TRPC5 in amygdala function and fear-related behavior. Cell (2009) 1.72
International Union of Pharmacology. LIV. Nomenclature and molecular relationships of inwardly rectifying potassium channels. Pharmacol Rev (2005) 1.63
Mammalian MagT1 and TUSC3 are required for cellular magnesium uptake and vertebrate embryonic development. Proc Natl Acad Sci U S A (2009) 1.60
Intracellular calcium strongly potentiates agonist-activated TRPC5 channels. J Gen Physiol (2009) 1.51
Rheotaxis guides mammalian sperm. Curr Biol (2013) 1.47
Real-time imaging of nuclear permeation by EGFP in single intact cells. Biophys J (2003) 1.46
The voltage-gated proton channel Hv1 enhances brain damage from ischemic stroke. Nat Neurosci (2012) 1.45
CatSperbeta, a novel transmembrane protein in the CatSper channel complex. J Biol Chem (2007) 1.43
MCU encodes the pore conducting mitochondrial calcium currents. Elife (2013) 1.39
CACNA1H mutations in autism spectrum disorders. J Biol Chem (2006) 1.35
A mechanism for the direct regulation of T-type calcium channels by Ca2+/calmodulin-dependent kinase II. J Neurosci (2003) 1.31
The channel kinase, TRPM7, is required for early embryonic development. Proc Natl Acad Sci U S A (2011) 1.29
The voltage-gated Na+ channel NaVBP has a role in motility, chemotaxis, and pH homeostasis of an alkaliphilic Bacillus. Proc Natl Acad Sci U S A (2004) 1.28
Phenotyping sensory nerve endings in vitro in the mouse. Nat Protoc (2009) 1.27
A spontaneous, recurrent mutation in divalent metal transporter-1 exposes a calcium entry pathway. PLoS Biol (2004) 1.26
Molecular dynamics of ion transport through the open conformation of a bacterial voltage-gated sodium channel. Proc Natl Acad Sci U S A (2013) 1.25
Calbindin-D28K dynamically controls TRPV5-mediated Ca2+ transport. EMBO J (2006) 1.25
Ion channels that control fertility in mammalian spermatozoa. Int J Dev Biol (2008) 1.23
Transient receptor potential cation channel, subfamily C, member 5 (TRPC5) is a cold-transducer in the peripheral nervous system. Proc Natl Acad Sci U S A (2011) 1.19
Role of the C-terminal domain in the structure and function of tetrameric sodium channels. Nat Commun (2013) 1.19
TRPM7 facilitates cholinergic vesicle fusion with the plasma membrane. Proc Natl Acad Sci U S A (2008) 1.17
A novel gene required for male fertility and functional CATSPER channel formation in spermatozoa. Nat Commun (2011) 1.16
Mechanism of persistent protein kinase D1 translocation and activation. Dev Cell (2003) 1.15
Bisandrographolide from Andrographis paniculata activates TRPV4 channels. J Biol Chem (2006) 1.14
POST, partner of stromal interaction molecule 1 (STIM1), targets STIM1 to multiple transporters. Proc Natl Acad Sci U S A (2011) 1.12
Ancestral Ca2+ signaling machinery in early animal and fungal evolution. Mol Biol Evol (2011) 1.12
Letm1, the mitochondrial Ca2+/H+ antiporter, is essential for normal glucose metabolism and alters brain function in Wolf-Hirschhorn syndrome. Proc Natl Acad Sci U S A (2013) 1.10
TATA-binding protein (TBP)-like factor (TLF) is a functional regulator of transcription: reciprocal regulation of the neurofibromatosis type 1 and c-fos genes by TLF/TRF2 and TBP. Mol Cell Biol (2005) 1.07
Cleavage of TRPM7 releases the kinase domain from the ion channel and regulates its participation in Fas-induced apoptosis. Dev Cell (2012) 1.07
Evolutionary genomics reveals lineage-specific gene loss and rapid evolution of a sperm-specific ion channel complex: CatSpers and CatSperbeta. PLoS One (2008) 1.05
Citral sensing by Transient [corrected] receptor potential channels in dorsal root ganglion neurons. PLoS One (2008) 1.01
TRP channels and mice deficient in TRP channels. Pflugers Arch (2005) 1.00
TRPM7, the Mg(2+) inhibited channel and kinase. Adv Exp Med Biol (2011) 0.99
Targeted cytosolic delivery of cell-impermeable compounds by nanoparticle-mediated, light-triggered endosome disruption. Nano Lett (2010) 0.99
Timing of myocardial trpm7 deletion during cardiogenesis variably disrupts adult ventricular function, conduction, and repolarization. Circulation (2013) 0.97
The G-protein-gated K+ channel, IKACh, is required for regulation of pacemaker activity and recovery of resting heart rate after sympathetic stimulation. J Gen Physiol (2013) 0.97
Controlled delivery of bioactive molecules into live cells using the bacterial mechanosensitive channel MscL. Nat Commun (2012) 0.93
Simultaneous knockout of Slo3 and CatSper1 abolishes all alkalization- and voltage-activated current in mouse spermatozoa. J Gen Physiol (2013) 0.92
Ion channel-kinase TRPM7 is required for maintaining cardiac automaticity. Proc Natl Acad Sci U S A (2013) 0.92
Analysis of the selectivity filter of the voltage-gated sodium channel Na(v)Rh. Cell Res (2012) 0.92
ATP-activated P2X2 current in mouse spermatozoa. Proc Natl Acad Sci U S A (2011) 0.91
A STIMulus Package puts orai calcium channels to work. Cell (2009) 0.91
Anion-sensitive fluorophore identifies the Drosophila swell-activated chloride channel in a genome-wide RNA interference screen. PLoS One (2012) 0.90
Calpain cleaves and activates the TRPC5 channel to participate in semaphorin 3A-induced neuronal growth cone collapse. Proc Natl Acad Sci U S A (2012) 0.89
Structural characterization of the mouse Girk genes. Gene (2002) 0.88
Sperm patch-clamp. Methods Enzymol (2013) 0.85
Decreased anxiety-like behavior and Gαq/11-dependent responses in the amygdala of mice lacking TRPC4 channels. J Neurosci (2014) 0.85
Flexibility in surface-exposed loops in a virus capsid mediates escape from antibody neutralization. J Virol (2014) 0.83
The voltage-gated Na+ channel NaVBP co-localizes with methyl-accepting chemotaxis protein at cell poles of alkaliphilic Bacillus pseudofirmus OF4. Microbiology (2007) 0.82
The MUPP1-SynGAPalpha protein complex does not mediate activity-induced LTP. Mol Cell Neurosci (2008) 0.80
Modified herpes simplex virus delivery of enhanced GFP into the central nervous system. J Neurosci Methods (2002) 0.77