Pneumonia: still the old man's friend?

New perspectives on community-acquired pneumonia in 388 406 patients. Results from a nationwide mandatory performance measurement programme in healthcare quality. Thorax (2009) 3.21

Inflammatory markers at hospital discharge predict subsequent mortality after pneumonia and sepsis. Am J Respir Crit Care Med (2008) 2.37

Long-term survival after hospitalization for community-acquired and healthcare-associated pneumonia. Respiration (2009) 1.54

Incidence of community-acquired lower respiratory tract infections and pneumonia among older adults in the United Kingdom: a population-based study. PLoS One (2013) 1.43

Efficacy of osteopathic manipulation as an adjunctive treatment for hospitalized patients with pneumonia: a randomized controlled trial. Osteopath Med Prim Care (2010) 1.19

Functional disability, cognitive impairment, and depression after hospitalization for pneumonia. Am J Med (2013) 1.17

Elevated hemostasis markers after pneumonia increases one-year risk of all-cause and cardiovascular deaths. PLoS One (2011) 1.17

The multidimensional prognostic index predicts short- and long-term mortality in hospitalized geriatric patients with pneumonia. J Gerontol A Biol Sci Med Sci (2009) 1.15

Changing needs of community-acquired pneumonia. J Antimicrob Chemother (2011) 1.14

Is pneumonia still the old man's friend? Arch Intern Med (2003) 1.07

Using data-driven rules to predict mortality in severe community acquired pneumonia. PLoS One (2014) 1.06

Long-term prognosis in community-acquired pneumonia. Curr Opin Infect Dis (2013) 1.06

Streptococcus pneumoniae translocates into the myocardium and forms unique microlesions that disrupt cardiac function. PLoS Pathog (2014) 1.01

Overview of community-acquired pneumonia and the role of inflammatory mechanisms in the immunopathogenesis of severe pneumococcal disease. Mediators Inflamm (2013) 1.01

Incidence and cost of pneumonia in older adults with COPD in the United States. PLoS One (2013) 0.99

An exploratory spatial analysis of pneumonia and influenza hospitalizations in Ontario by age and gender. Epidemiol Infect (2006) 0.99

One-year outcomes of community-acquired and healthcare-associated pneumonia in the Veterans Affairs Healthcare System. Int J Infect Dis (2011) 0.97

Risk factors and severity scores in hospitalized patients with community-acquired pneumonia: prediction of severity and mortality. Eur J Clin Microbiol Infect Dis (2011) 0.92

The effects of age on inflammatory and coagulation-fibrinolysis response in patients hospitalized for pneumonia. PLoS One (2010) 0.90

Mortality in Danish patients with nonmelanoma skin cancer, 1978-2001. Br J Dermatol (2008) 0.90

The role of biomarkers in community-acquired pneumonia: predicting mortality and response to adjunctive therapy. Crit Care (2008) 0.90

The management of community-acquired pneumonia in the elderly. Eur J Intern Med (2013) 0.88

Community-acquired pneumonia in elderly patients. Aging health (2009) 0.88

Cardiotoxicity during invasive pneumococcal disease. Am J Respir Crit Care Med (2015) 0.86

Effects of Aging on Inflammation and Hemostasis through the Continuum of Critical Illness. Aging Dis (2011) 0.86

Dysbiosis of upper respiratory tract microbiota in elderly pneumonia patients. ISME J (2015) 0.85

Long-term mortality after community-acquired pneumonia--impacts of diabetes and newly discovered hyperglycaemia: a prospective, observational cohort study. BMJ Open (2014) 0.85

The evolution of nutrition in critical care: how much, how soon? Crit Care (2013) 0.83

Mortality after hospitalization for pneumonia among individuals with HIV, 1995-2008: a Danish cohort study. PLoS One (2009) 0.83

Low zinc status: a new risk factor for pneumonia in the elderly? Nutr Rev (2010) 0.83

Clinical and economic burden of community-acquired pneumonia among adults in the Czech Republic, Hungary, Poland and Slovakia. PLoS One (2013) 0.82

Pneumonia severity, comorbidity and 1-year mortality in predominantly older adults with community-acquired pneumonia: a cohort study. BMC Infect Dis (2015) 0.82

Quantifying the role of adverse events in the mortality difference between first and second-generation antipsychotics in older adults: systematic review and meta-synthesis. PLoS One (2014) 0.81

A mathematical model of intrahost pneumococcal pneumonia infection dynamics in murine strains. J Theor Biol (2014) 0.81

Does socioeconomic status affect mortality subsequent to hospital admission for community acquired pneumonia among older persons? J Negat Results Biomed (2005) 0.81

Depression and risk of hospitalization for pneumonia in a cohort study of older Americans. J Psychosom Res (2014) 0.80

Risk Factors for Long-Term Mortality after Hospitalization for Community-Acquired Pneumonia: A 5-Year Prospective Follow-Up Study. PLoS One (2016) 0.80

Diagnoses of early and late readmissions after hospitalization for pneumonia. A systematic review. Ann Am Thorac Soc (2014) 0.77

When is critical illness not like an asteroid strike? Am J Respir Crit Care Med (2013) 0.77

Pneumococcal Conjugated Vaccine Reduces the High Mortality for Community-Acquired Pneumonia in the Elderly: an Italian Regional Experience. PLoS One (2016) 0.76

Methodological criticisms in the evaluation of Pneumococcal Conjugate Vaccine effectiveness. J Prev Med Hyg (2015) 0.76

Skeletal Muscle Weakness Is Associated With Both Early and Late Mortality After Acute Respiratory Distress Syndrome. Crit Care Med (2017) 0.76

Do findings of high mortality from pneumonia in the elderly make it the old man's friend? Arch Intern Med (2004) 0.75

Prognostic implications of aspiration pneumonia in patients with community acquired pneumonia: A systematic review with meta-analysis. Sci Rep (2016) 0.75

Facts and ideas from anywhere. Proc (Bayl Univ Med Cent) (2003) 0.75

Community-acquired pneumonia in the United Kingdom: a call to action. Pneumonia (Nathan) (2017) 0.75

Individual and health system variation in rehospitalizations the year after pneumonia. Medicine (Baltimore) (2017) 0.75

Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012. Crit Care Med (2013) 39.56

Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Crit Care Med (2008) 31.57

Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012. Intensive Care Med (2013) 17.37

A randomized trial of protocol-based care for early septic shock. N Engl J Med (2014) 16.05

Unexpected increased mortality after implementation of a commercially sold computerized physician order entry system. Pediatrics (2005) 15.40

Physician staffing patterns and clinical outcomes in critically ill patients: a systematic review. JAMA (2002) 9.89

RIFLE criteria for acute kidney injury are associated with hospital mortality in critically ill patients: a cohort analysis. Crit Care (2006) 9.29

Use of intensive care at the end of life in the United States: an epidemiologic study. Crit Care Med (2004) 9.06

Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Intensive Care Med (2007) 8.33

The Surviving Sepsis Campaign: results of an international guideline-based performance improvement program targeting severe sepsis. Crit Care Med (2010) 6.69

National estimates of severe sepsis in United States emergency departments. Crit Care Med (2007) 5.99

Understanding the inflammatory cytokine response in pneumonia and sepsis: results of the Genetic and Inflammatory Markers of Sepsis (GenIMS) Study. Arch Intern Med (2007) 5.65

Nighttime intensivist staffing and mortality among critically ill patients. N Engl J Med (2012) 5.22

Variation in critical care services across North America and Western Europe. Crit Care Med (2008) 5.00

The epidemiology of severe sepsis in children in the United States. Am J Respir Crit Care Med (2002) 4.72

The Surviving Sepsis Campaign: results of an international guideline-based performance improvement program targeting severe sepsis. Intensive Care Med (2010) 4.64

Duration of cardiopulmonary resuscitation and illness category impact survival and neurologic outcomes for in-hospital pediatric cardiac arrests. Circulation (2013) 4.46

The effect of multidisciplinary care teams on intensive care unit mortality. Arch Intern Med (2010) 4.41

Cost-effectiveness of drotrecogin alfa (activated) in the treatment of severe sepsis. Crit Care Med (2003) 4.04

Effect of eritoran, an antagonist of MD2-TLR4, on mortality in patients with severe sepsis: the ACCESS randomized trial. JAMA (2013) 3.78

Early reversal of pediatric-neonatal septic shock by community physicians is associated with improved outcome. Pediatrics (2003) 3.49

A comparison of three methods to estimate baseline creatinine for RIFLE classification. Nephrol Dial Transplant (2010) 3.45

Risk prediction with procalcitonin and clinical rules in community-acquired pneumonia. Ann Emerg Med (2008) 3.44

Severe sepsis in pre-hospital emergency care: analysis of incidence, care, and outcome. Am J Respir Crit Care Med (2012) 3.36

The epidemiology of mechanical ventilation use in the United States. Crit Care Med (2010) 3.28

Drotrecogin alfa (activated) administration across clinically important subgroups of patients with severe sepsis. Crit Care Med (2003) 3.18

Racial variation in the incidence, care, and outcomes of severe sepsis: analysis of population, patient, and hospital characteristics. Am J Respir Crit Care Med (2007) 3.17

The next generation of sepsis clinical trial designs: what is next after the demise of recombinant human activated protein C?*. Crit Care Med (2014) 3.17

Intensive care unit quality improvement: a "how-to" guide for the interdisciplinary team. Crit Care Med (2006) 3.15

Renal failure in the ICU: comparison of the impact of acute renal failure and end-stage renal disease on ICU outcomes. Kidney Int (2002) 3.07

Hospitalized community-acquired pneumonia in the elderly: age- and sex-related patterns of care and outcome in the United States. Am J Respir Crit Care Med (2002) 3.02

Conditional outlier detection for clinical alerting. AMIA Annu Symp Proc (2010) 2.99

Acute kidney injury in non-severe pneumonia is associated with an increased immune response and lower survival. Kidney Int (2009) 2.97

Prospective meta-analysis using individual patient data in intensive care medicine. Intensive Care Med (2009) 2.93

Organizational characteristics, outcomes, and resource use in 78 Brazilian intensive care units: the ORCHESTRA study. Intensive Care Med (2015) 2.92

Three-year outcomes for Medicare beneficiaries who survive intensive care. JAMA (2010) 2.87

The association of sepsis syndrome and organ dysfunction with mortality in emergency department patients with suspected infection. Ann Emerg Med (2006) 2.84

The adult respiratory distress syndrome cognitive outcomes study: long-term neuropsychological function in survivors of acute lung injury. Am J Respir Crit Care Med (2012) 2.72

Trends in the epidemiology of pediatric severe sepsis*. Pediatr Crit Care Med (2013) 2.67

Critical care medicine training and certification for emergency physicians. Ann Emerg Med (2005) 2.67

End-of-life care for the critically ill: A national intensive care unit survey. Crit Care Med (2006) 2.61

Disability among elderly survivors of mechanical ventilation. Am J Respir Crit Care Med (2010) 2.50

Effects of drotrecogin alfa (activated) on organ dysfunction in the PROWESS trial. Crit Care Med (2003) 2.44

Harmonizing international trials of early goal-directed resuscitation for severe sepsis and septic shock: methodology of ProCESS, ARISE, and ProMISe. Intensive Care Med (2013) 2.44

Prioritizing the organization and management of intensive care services in the United States: the PrOMIS Conference. Crit Care Med (2007) 2.42

Relationship between staff perceptions of hospital norms and hospital-level end-of-life treatment intensity. J Palliat Med (2007) 2.39

Long-term mortality and medical care charges in patients with severe sepsis. Crit Care Med (2003) 2.39

Inflammatory markers at hospital discharge predict subsequent mortality after pneumonia and sepsis. Am J Respir Crit Care Med (2008) 2.37

Is survival better at hospitals with higher "end-of-life" treatment intensity? Med Care (2010) 2.35

A randomized, double-blind, placebo-controlled trial of TAK-242 for the treatment of severe sepsis. Crit Care Med (2010) 2.31

Survival after liver transplantation in the United States: a disease-specific analysis of the UNOS database. Liver Transpl (2004) 2.31

Growth of intensive care unit resource use and its estimated cost in Medicare. Crit Care Med (2008) 2.31

Severe sepsis epidemiology: sampling, selection, and society. Crit Care (2004) 2.28

Infection rate and acute organ dysfunction risk as explanations for racial differences in severe sepsis. JAMA (2010) 2.27

Healthcare costs and long-term outcomes after acute respiratory distress syndrome: A phase III trial of inhaled nitric oxide. Crit Care Med (2006) 2.27

Incidence, cost, and mortality of neutropenia hospitalization associated with chemotherapy. Cancer (2005) 2.25

Perceptions of safety culture vary across the intensive care units of a single institution. Crit Care Med (2007) 2.24

Hospital deaths in patients with sepsis from 2 independent cohorts. JAMA (2014) 2.23

Plasma neutrophil gelatinase-associated lipocalin predicts recovery from acute kidney injury following community-acquired pneumonia. Kidney Int (2011) 2.22

Posttraumatic stress and complicated grief in family members of patients in the intensive care unit. J Gen Intern Med (2008) 2.12

Critical care medicine training and certification for emergency physicians. Crit Care Med (2005) 2.12

Haloperidol use is associated with lower hospital mortality in mechanically ventilated patients. Crit Care Med (2005) 2.11

Severe sepsis and septic shock. N Engl J Med (2013) 2.10

Outlier detection for patient monitoring and alerting. J Biomed Inform (2012) 2.10

A comparison of critical care research funding and the financial burden of critical illness in the United States. Crit Care Med (2012) 2.07

Do hospitals provide lower quality of care to black patients for pneumonia? Crit Care Med (2010) 2.07

Relationship Between ICU Length of Stay and Long-Term Mortality for Elderly ICU Survivors. Crit Care Med (2016) 2.03

Forging a critical alliance: Addressing the research needs of the United States critical illness and injury community. Crit Care Med (2009) 2.03

Use of intensive care services during terminal hospitalizations in England and the United States. Am J Respir Crit Care Med (2009) 2.00

Assessing the feasibility of the American College of Surgeons' benchmarks for the triage of trauma patients. Arch Surg (2011) 1.95

Critical care bed growth in the United States. A comparison of regional and national trends. Am J Respir Crit Care Med (2015) 1.93

How does lack of insurance affect use of intensive care? A population-based study. Crit Care Med (2006) 1.92

Cost-effectiveness of inhaled nitric oxide in the treatment of neonatal respiratory failure in the United States. Pediatrics (2003) 1.92