Published in Proc Natl Acad Sci U S A on February 14, 2003
Genome engineering of Drosophila with the CRISPR RNA-guided Cas9 nuclease. Genetics (2013) 8.56
MicroRNA-9a ensures the precise specification of sensory organ precursors in Drosophila. Genes Dev (2006) 6.30
Efficient gene targeting in Drosophila with zinc-finger nucleases. Genetics (2006) 4.47
Site-specific transformation of Drosophila via phiC31 integrase-mediated cassette exchange. Genetics (2006) 3.94
A Polycomb group protein complex with sequence-specific DNA-binding and selective methyl-lysine-binding activities. Genes Dev (2006) 3.49
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Molecular evolution and functional characterization of Drosophila insulin-like peptides. PLoS Genet (2010) 2.80
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Rhomboid family pseudoproteases use the ER quality control machinery to regulate intercellular signaling. Cell (2011) 2.71
Genetic manipulation of genes and cells in the nervous system of the fruit fly. Neuron (2011) 2.54
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Drosophila lacking microRNA miR-278 are defective in energy homeostasis. Genes Dev (2006) 2.26
Optimized gene editing technology for Drosophila melanogaster using germ line-specific Cas9. Proc Natl Acad Sci U S A (2013) 2.13
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A Drosophila gustatory receptor essential for aversive taste and inhibiting male-to-male courtship. Curr Biol (2009) 2.10
Homologous gene targeting in Caenorhabditis elegans by biolistic transformation. Nucleic Acids Res (2004) 2.06
Multiple gustatory receptors required for the caffeine response in Drosophila. Proc Natl Acad Sci U S A (2009) 2.02
Systematic discovery of Rab GTPases with synaptic functions in Drosophila. Curr Biol (2011) 1.99
Genomic deletions of the Drosophila melanogaster Hsp70 genes. Genetics (2004) 1.93
Gr64f is required in combination with other gustatory receptors for sugar detection in Drosophila. Curr Biol (2008) 1.89
The homologous chromosome is an effective template for the repair of mitotic DNA double-strand breaks in Drosophila. Genetics (2003) 1.87
High efficiency site-specific genetic engineering of the mosquito genome. Insect Mol Biol (2006) 1.87
Epidermal cells are the primary phagocytes in the fragmentation and clearance of degenerating dendrites in Drosophila. Neuron (2014) 1.87
Highly efficient and specific genome editing in silkworm using custom TALENs. PLoS One (2012) 1.80
WntD is a feedback inhibitor of Dorsal/NF-kappaB in Drosophila development and immunity. Nature (2005) 1.75
Efficient ends-out gene targeting in Drosophila. Genetics (2008) 1.74
Trabid, a new positive regulator of Wnt-induced transcription with preference for binding and cleaving K63-linked ubiquitin chains. Genes Dev (2008) 1.74
Hierarchical chemosensory regulation of male-male social interactions in Drosophila. Nat Neurosci (2011) 1.72
Dscam2 mediates axonal tiling in the Drosophila visual system. Nature (2007) 1.66
Accelerated homologous recombination and subsequent genome modification in Drosophila. Development (2013) 1.55
Rhythm defects caused by newly engineered null mutations in Drosophila's cryptochrome gene. Genetics (2007) 1.53
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Drosophila TRPA1 channel mediates chemical avoidance in gustatory receptor neurons. Proc Natl Acad Sci U S A (2010) 1.51
The essential role of Drosophila HIRA for de novo assembly of paternal chromatin at fertilization. PLoS Genet (2007) 1.50
Genetic and biochemical definition of the Hedgehog receptor. Genes Dev (2010) 1.47
Methyl farnesoate plays a dual role in regulating Drosophila metamorphosis. PLoS Genet (2015) 1.44
Midline crossing by gustatory receptor neuron axons is regulated by fruitless, doublesex and the Roundabout receptors. Development (2010) 1.42
Enhanced specificity and efficiency of the CRISPR/Cas9 system with optimized sgRNA parameters in Drosophila. Cell Rep (2014) 1.35
Tissue-autonomous function of Drosophila seipin in preventing ectopic lipid droplet formation. PLoS Genet (2011) 1.30
Drosophila lowfat, a novel modulator of Fat signaling. Development (2009) 1.29
Drosophila SETDB1 is required for chromosome 4 silencing. PLoS Genet (2007) 1.29
Turning males on: activation of male courtship behavior in Drosophila melanogaster. PLoS One (2011) 1.26
Recombinase-mediated cassette exchange provides a versatile platform for gene targeting: knockout of miR-31b. Genetics (2009) 1.26
Drosophila microRNAs 263a/b confer robustness during development by protecting nascent sense organs from apoptosis. PLoS Biol (2010) 1.26
Gene deletions by ends-in targeting in Drosophila melanogaster. Genetics (2004) 1.20
A short receptor downregulates JAK/STAT signalling to control the Drosophila cellular immune response. PLoS Biol (2010) 1.20
Multiple-pathway analysis of double-strand break repair mutations in Drosophila. PLoS Genet (2007) 1.20
A myocardin-related transcription factor regulates activity of serum response factor in Drosophila. Proc Natl Acad Sci U S A (2004) 1.16
The role of the histone H2A ubiquitinase Sce in Polycomb repression. Development (2011) 1.14
piggybac- and PhiC31-mediated genetic transformation of the Asian tiger mosquito, Aedes albopictus (Skuse). PLoS Negl Trop Dis (2010) 1.14
The Bax/Bak ortholog in Drosophila, Debcl, exerts limited control over programmed cell death. Development (2008) 1.14
Consequences of eukaryotic enhancer architecture for gene expression dynamics, development, and fitness. PLoS Genet (2011) 1.13
SNX3 controls Wingless/Wnt secretion through regulating retromer-dependent recycling of Wntless. Cell Res (2011) 1.13
Transcriptional repression by PRC1 in the absence of H2A monoubiquitylation. Genes Dev (2015) 1.12
The full-of-bacteria gene is required for phagosome maturation during immune defense in Drosophila. J Cell Biol (2011) 1.12
Requirement for an enzymatic visual cycle in Drosophila. Curr Biol (2009) 1.11
An odorant-binding protein required for suppression of sweet taste by bitter chemicals. Neuron (2013) 1.11
Telomere loss provokes multiple pathways to apoptosis and produces genomic instability in Drosophila melanogaster. Genetics (2008) 1.10
CRISPR/Cas9-mediated genome engineering and the promise of designer flies on demand. Fly (Austin) (2013) 1.10
Probabilistic splicing of Dscam1 establishes identity at the level of single neurons. Cell (2013) 1.05
Sialyltransferase regulates nervous system function in Drosophila. J Neurosci (2010) 1.05
Loss of Hsp70 in Drosophila is pleiotropic, with effects on thermotolerance, recovery from heat shock and neurodegeneration. Genetics (2005) 1.04
Drosophila CPEB Orb2A mediates memory independent of Its RNA-binding domain. Neuron (2012) 1.04
MTERF3 regulates mitochondrial ribosome biogenesis in invertebrates and mammals. PLoS Genet (2013) 1.01
Serrano (sano) functions with the planar cell polarity genes to control tracheal tube length. PLoS Genet (2009) 1.01
Optimising homing endonuclease gene drive performance in a semi-refractory species: the Drosophila melanogaster experience. PLoS One (2013) 1.01
Regulation of smoothened by Drosophila G-protein-coupled receptor kinases. Dev Biol (2009) 1.00
I-BAR protein antagonism of endocytosis mediates directional sensing during guided cell migration. J Cell Biol (2010) 1.00
Control of antagonistic components of the hedgehog signaling pathway by microRNAs in Drosophila. Genetics (2008) 0.99
Imaging transcription dynamics at endogenous genes in living Drosophila tissues. Methods (2008) 0.99
A conserved F box regulatory complex controls proteasome activity in Drosophila. Cell (2011) 0.98
Tandem repeat coupled with endonuclease cleavage (TREC): a seamless modification tool for genome engineering in yeast. Nucleic Acids Res (2010) 0.97
Drosophila G9a is a nonessential gene. Genetics (2007) 0.97
Reverse genetics in eukaryotes. Biol Cell (2010) 0.97
Endodomain diversity in the Drosophila Dscam and its roles in neuronal morphogenesis. J Neurosci (2009) 0.96
Overlapping roles of Drosophila Drak and Rok kinases in epithelial tissue morphogenesis. Mol Biol Cell (2010) 0.95
Drosophila TRPM channel is essential for the control of extracellular magnesium levels. PLoS One (2010) 0.95
An enhanced gene targeting toolkit for Drosophila: Golic+. Genetics (2015) 0.95
Spps, a Drosophila Sp1/KLF family member, binds to PREs and is required for PRE activity late in development. Development (2010) 0.95
Drosophila, genetic screens, and cardiac function. Circ Res (2011) 0.95
RNA-guided nucleases: a new era for engineering the genomes of model and nonmodel organisms. Genetics (2013) 0.95
A novel partner of Scalloped regulates Hippo signaling via antagonizing Scalloped-Yorkie activity. Cell Res (2013) 0.95
The Drosophila SUN protein Spag4 cooperates with the coiled-coil protein Yuri Gagarin to maintain association of the basal body and spermatid nucleus. J Cell Sci (2010) 0.93
A conserved long noncoding RNA affects sleep behavior in Drosophila. Genetics (2011) 0.92
Initiator elements function to determine the activity state of BX-C enhancers. PLoS Genet (2010) 0.92
An efficient method to generate chromosomal rearrangements by targeted DNA double-strand breaks in Drosophila melanogaster. Genome Res (2004) 0.92
Combining recombineering and ends-out homologous recombination to systematically characterize Drosophila gene families: Rab GTPases as a case study. Commun Integr Biol (2012) 0.92
Overlapping functions of microRNAs in control of apoptosis during Drosophila embryogenesis. Cell Death Differ (2011) 0.91
A male-specific fatty acid omega-hydroxylase, SXE1, is necessary for efficient male mating in Drosophila melanogaster. Genetics (2008) 0.91
Dtorsin, the Drosophila ortholog of the early-onset dystonia TOR1A (DYT1), plays a novel role in dopamine metabolism. PLoS One (2011) 0.90
Sphingosine kinases and their metabolites modulate endolysosomal trafficking in photoreceptors. J Cell Biol (2011) 0.90
Meganuclease and transposon mediated transgenesis in medaka. Genome Biol (2007) 0.90
The oscillating miRNA 959-964 cluster impacts Drosophila feeding time and other circadian outputs. Cell Metab (2012) 0.90
Stereotypic founder cell patterning and embryonic muscle formation in Drosophila require nautilus (MyoD) gene function. Proc Natl Acad Sci U S A (2007) 0.90
Role of the DSC1 channel in regulating neuronal excitability in Drosophila melanogaster: extending nervous system stability under stress. PLoS Genet (2013) 0.90
Context differences reveal insulator and activator functions of a Su(Hw) binding region. PLoS Genet (2008) 0.89
W::Neo: a novel dual-selection marker for high efficiency gene targeting in Drosophila. PLoS One (2012) 0.89
New research resources at the Bloomington Drosophila Stock Center. Fly (Austin) (2010) 0.89
The Drosophila visual cycle and de novo chromophore synthesis depends on rdhB. J Neurosci (2012) 0.89
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The homologous chromosome is an effective template for the repair of mitotic DNA double-strand breaks in Drosophila. Genetics (2003) 1.87
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Telomere loss provokes multiple pathways to apoptosis and produces genomic instability in Drosophila melanogaster. Genetics (2008) 1.10
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Highly efficient sex chromosome interchanges produced by I-CreI expression in Drosophila. Genetics (2005) 0.97
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