Published in Addiction on April 01, 2003
Excess mortality rates in a cohort of patients infected with the hepatitis C virus: a prospective study. Gut (2007) 1.58
Determinants of overdose incidents among illicit opioid users in 5 Canadian cities. CMAJ (2004) 1.44
Factors associated with mortality in Scottish patients receiving methadone in primary care: retrospective cohort study. BMJ (2009) 1.42
Take-home emergency naloxone to prevent heroin overdose deaths after prison release: rationale and practicalities for the N-ALIVE randomized trial. J Urban Health (2013) 1.34
Drug-related mortality and fatal overdose risk: pilot cohort study of heroin users recruited from specialist drug treatment sites in London. J Urban Health (2003) 1.29
Development of a coroner-based surveillance system for drug-related deaths in Los Angeles county. J Urban Health (2010) 0.91
Methadone-related and heroin-related deaths among opiate users: methadone helps save lives. Addiction (2003) 0.81
Do young heroin users in Madrid, Barcelona and Seville have sufficient knowledge of the risk factors for unintentional opioid overdose? J Urban Health (2006) 0.78
The relative risk of fatal poisoning by methadone or buprenorphine within the wider population of England and Wales. BMJ Open (2015) 0.78
Problem drug use the public health imperative: what some of the literature says. Subst Abuse Treat Prev Policy (2009) 0.75
Influence of war on quantitative and qualitative changes in drug-induced mortality in Split-Dalmatia County, Croatia. Croat Med J (2011) 0.75
Examining Fatal Opioid Overdoses in Marion County, Indiana. J Urban Health (2017) 0.75
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet (2008) 22.35
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes. Nat Genet (2007) 19.04
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
Genome-wide association analysis identifies 20 loci that influence adult height. Nat Genet (2008) 16.92
Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet (2008) 15.94
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nat Genet (2007) 12.62
Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet (2009) 12.44
Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. Nat Genet (2008) 12.32
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. Nature (2010) 12.27
Variants in MTNR1B influence fasting glucose levels. Nat Genet (2008) 10.85
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94
Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations. Nat Genet (2009) 6.39
Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease. Nat Genet (2011) 6.36
Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides. Nat Genet (2008) 6.06
Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet (2009) 5.81
Effect of lower sodium intake on health: systematic review and meta-analyses. BMJ (2013) 5.78
Aircraft noise and cardiovascular disease near Heathrow airport in London: small area study. BMJ (2013) 5.74
Common genetic variation near MC4R is associated with waist circumference and insulin resistance. Nat Genet (2008) 5.55
A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk. Nat Genet (2008) 5.49
Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia. Nat Genet (2009) 5.43
Human metabolic phenotype diversity and its association with diet and blood pressure. Nature (2008) 5.41
Salt intakes around the world: implications for public health. Int J Epidemiol (2009) 5.05
Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations. PLoS Genet (2009) 4.97
Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes. Am J Hum Genet (2008) 4.69
Size matters: just how big is BIG?: Quantifying realistic sample size requirements for human genome epidemiology. Int J Epidemiol (2008) 4.53
Pervasive sharing of genetic effects in autoimmune disease. PLoS Genet (2011) 4.42
A polymorphism within the G6PC2 gene is associated with fasting plasma glucose levels. Science (2008) 4.38
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet (2014) 4.13
Genome-wide association study identifies five loci associated with lung function. Nat Genet (2009) 4.10
Genetic variants influencing circulating lipid levels and risk of coronary artery disease. Arterioscler Thromb Vasc Biol (2010) 4.08
Interpreting posterior relative risk estimates in disease-mapping studies. Environ Health Perspect (2004) 3.81
Common variation in the FTO gene alters diabetes-related metabolic traits to the extent expected given its effect on BMI. Diabetes (2008) 3.76
Genetic loci influencing kidney function and chronic kidney disease. Nat Genet (2010) 3.75
Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels. Circulation (2011) 3.68
Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci. Nat Genet (2011) 3.46
Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human. Nature (2012) 3.41
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet (2011) 3.40
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21
Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. Nat Genet (2011) 3.18
New gene functions in megakaryopoiesis and platelet formation. Nature (2011) 3.14
Blood pressure and the global burden of disease 2000. Part II: estimates of attributable burden. J Hypertens (2006) 3.12
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. Nat Genet (2011) 3.03
Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet (2013) 2.92
A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk. Nature (2010) 2.88
SLC2A9 is a high-capacity urate transporter in humans. PLoS Med (2008) 2.87
Seventy-five genetic loci influencing the human red blood cell. Nature (2012) 2.77
Changing international trends in mortality rates for liver, biliary and pancreatic tumours. J Hepatol (2002) 2.70
Dietary sources of sodium in China, Japan, the United Kingdom, and the United States, women and men aged 40 to 59 years: the INTERMAP study. J Am Diet Assoc (2010) 2.60
A genome-wide association meta-analysis identifies new childhood obesity loci. Nat Genet (2012) 2.60
Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus. Nature (2011) 2.59
MultiPhen: joint model of multiple phenotypes can increase discovery in GWAS. PLoS One (2012) 2.56
Bayesian inference for generalized linear mixed models. Biostatistics (2009) 2.44
Blood pressure and the global burden of disease 2000. Part 1: estimates of blood pressure levels. J Hypertens (2006) 2.43
Genetic variation in SCN10A influences cardiac conduction. Nat Genet (2010) 2.30
Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight. Nat Genet (2010) 2.30
Sugar-sweetened beverage, sugar intake of individuals, and their blood pressure: international study of macro/micronutrients and blood pressure. Hypertension (2011) 2.29
Extreme clonality in lymphoblastoid cell lines with implications for allele specific expression analyses. PLoS One (2008) 2.28
Effect of increased potassium intake on cardiovascular risk factors and disease: systematic review and meta-analyses. BMJ (2013) 2.28
Haplotypes of the WNK1 gene associate with blood pressure variation in a severely hypertensive population from the British Genetics of Hypertension study. Hum Mol Genet (2005) 2.27
Multi-level modelling, the ecologic fallacy, and hybrid study designs. Int J Epidemiol (2009) 2.26
Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases. PLoS Genet (2011) 2.25
Vascularized groin lymph node transfer using the wrist as a recipient site for management of postmastectomy upper extremity lymphedema. Plast Reconstr Surg (2009) 2.25
Paediatric cardiac surgical mortality in England after Bristol: descriptive analysis of hospital episode statistics 1991-2002. BMJ (2004) 2.20
Hemoglobin concentration in pregnancy and perinatal mortality: a London-based cohort study. Am J Obstet Gynecol (2005) 2.20
A nutrient-wide association study on blood pressure. Circulation (2012) 2.19
Genome-wide association study identifies variants in TMPRSS6 associated with hemoglobin levels. Nat Genet (2009) 2.19
Meta-analysis of studies of alcohol and breast cancer with consideration of the methodological issues. Cancer Causes Control (2006) 2.17
Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. Am J Hum Genet (2010) 2.15
Early life factors and blood pressure at age 31 years in the 1966 northern Finland birth cohort. Hypertension (2004) 2.14
Hand, foot, and mouth disease in China: patterns of spread and transmissibility. Epidemiology (2011) 2.13
The UK Biobank sample handling and storage validation studies. Int J Epidemiol (2008) 2.12
Relation of iron and red meat intake to blood pressure: cross sectional epidemiological study. BMJ (2008) 2.09
Methodological issues in cohort studies that relate sodium intake to cardiovascular disease outcomes: a science advisory from the American Heart Association. Circulation (2014) 2.05
Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption. Proc Natl Acad Sci U S A (2011) 2.01
A powerful and flexible statistical framework for testing hypotheses of allele-specific gene expression from RNA-seq data. Genome Res (2011) 2.00
Does gestation vary by ethnic group? A London-based study of over 122,000 pregnancies with spontaneous onset of labour. Int J Epidemiol (2004) 1.97
Locomotion with flexible propulsors: II. Computational modeling of pectoral fin swimming in sunfish. Bioinspir Biomim (2006) 1.95
Genetic determinants of height growth assessed longitudinally from infancy to adulthood in the northern Finland birth cohort 1966. PLoS Genet (2009) 1.89
Bayesian analysis of population PK/PD models: general concepts and software. J Pharmacokinet Pharmacodyn (2002) 1.89
Cognitive and subjective dose-response effects of acute oral Delta 9-tetrahydrocannabinol (THC) in infrequent cannabis users. Psychopharmacology (Berl) (2002) 1.84
Blood pressure differences between northern and southern Chinese: role of dietary factors: the International Study on Macronutrients and Blood Pressure. Hypertension (2004) 1.84
Measuring deprivation in England and Wales using 2001 Carstairs scores. Health Stat Q (2006) 1.82
Long-term leisure-time physical activity and serum metabolome. Circulation (2012) 1.81
Inherited variation in vitamin D genes is associated with predisposition to autoimmune disease type 1 diabetes. Diabetes (2011) 1.78
Socio-economic status and oesophageal cancer: results from a population-based case-control study in a high-risk area. Int J Epidemiol (2009) 1.77
Assessment of analytical reproducibility of 1H NMR spectroscopy based metabonomics for large-scale epidemiological research: the INTERMAP Study. Anal Chem (2006) 1.76
Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration. Eur Heart J (2011) 1.73
Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nat Genet (2013) 1.72