Published in Diabetes on April 01, 2003
Advanced glycation end products in infant formulas do not contribute to insulin resistance associated with their consumption. PLoS One (2013) 0.81
Semicarbazide-sensitive amine oxidase substrates fail to induce insulin-like effects in fat cells from AOC3 knockout mice. J Neural Transm (Vienna) (2007) 0.79
Discovery of a sensitive, selective, and tightly binding fluorogenic substrate of bovine plasma amine oxidase. J Org Chem (2009) 0.77
Studies on the insulinomimetic effects of benzylamine, exogenous substrate of semicarbazide-sensitive amine oxidase enzyme in streptozotocin induced diabetic rats. J Neural Transm (Vienna) (2007) 0.75
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Acarbose for prevention of type 2 diabetes mellitus: the STOP-NIDDM randomised trial. Lancet (2002) 9.48
Rosiglitazone evaluated for cardiovascular outcomes in oral agent combination therapy for type 2 diabetes (RECORD): a multicentre, randomised, open-label trial. Lancet (2009) 8.54
Acarbose treatment and the risk of cardiovascular disease and hypertension in patients with impaired glucose tolerance: the STOP-NIDDM trial. JAMA (2003) 8.47
Ribosomal protein S6 kinase 1 signaling regulates mammalian life span. Science (2009) 7.80
Reduction of macrophage infiltration and chemoattractant gene expression changes in white adipose tissue of morbidly obese subjects after surgery-induced weight loss. Diabetes (2005) 5.68
Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice. FASEB J (2007) 3.83
Critical role for the p110alpha phosphoinositide-3-OH kinase in growth and metabolic regulation. Nature (2006) 3.71
Mitochondrial dynamics in mammalian health and disease. Physiol Rev (2009) 3.59
Improvement of glycemic control in subjects with poorly controlled type 2 diabetes: comparison of two treatment algorithms using insulin glargine. Diabetes Care (2005) 3.55
Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism. A novel regulatory mechanism altered in obesity. J Biol Chem (2003) 3.45
Weight loss regulates inflammation-related genes in white adipose tissue of obese subjects. FASEB J (2004) 2.82
The Charcot-Marie-Tooth type 2A gene product, Mfn2, up-regulates fuel oxidation through expression of OXPHOS system. Hum Mol Genet (2005) 2.72
Heart failure events with rosiglitazone in type 2 diabetes: data from the RECORD clinical trial. Eur Heart J (2010) 2.68
Mitofusin 2 in POMC neurons connects ER stress with leptin resistance and energy imbalance. Cell (2013) 2.43
The role of insulin receptor substrate 2 in hypothalamic and beta cell function. J Clin Invest (2005) 2.40
Adipose tissue transcriptomic signature highlights the pathological relevance of extracellular matrix in human obesity. Genome Biol (2008) 2.22
Adipocyte lipases and defect of lipolysis in human obesity. Diabetes (2005) 2.14
Mitofusin 2 (Mfn2) links mitochondrial and endoplasmic reticulum function with insulin signaling and is essential for normal glucose homeostasis. Proc Natl Acad Sci U S A (2012) 2.00
Mitofusins 1/2 and ERRalpha expression are increased in human skeletal muscle after physical exercise. J Physiol (2005) 1.94
Worsening of obesity and metabolic status yields similar molecular adaptations in human subcutaneous and visceral adipose tissue: decreased metabolism and increased immune response. J Clin Endocrinol Metab (2010) 1.92
Evidence for a mitochondrial regulatory pathway defined by peroxisome proliferator-activated receptor-gamma coactivator-1 alpha, estrogen-related receptor-alpha, and mitofusin 2. Diabetes (2006) 1.91
Apelin, a newly identified adipokine up-regulated by insulin and obesity. Endocrinology (2005) 1.88
Partial inhibition of adipose tissue lipolysis improves glucose metabolism and insulin sensitivity without alteration of fat mass. PLoS Biol (2013) 1.87
Twelve- and 52-week efficacy of the dipeptidyl peptidase IV inhibitor LAF237 in metformin-treated patients with type 2 diabetes. Diabetes Care (2004) 1.75
Comparison between SLC3A1 and SLC7A9 cystinuria patients and carriers: a need for a new classification. J Am Soc Nephrol (2002) 1.73
CXC ligand 5 is an adipose-tissue derived factor that links obesity to insulin resistance. Cell Metab (2009) 1.68
Mfn2 modulates the UPR and mitochondrial function via repression of PERK. EMBO J (2013) 1.65
Increased ER-mitochondrial coupling promotes mitochondrial respiration and bioenergetics during early phases of ER stress. J Cell Sci (2011) 1.65
Identification of a pancreatic stellate cell population with properties of progenitor cells: new role for stellate cells in the pancreas. Biochem J (2009) 1.64
Changes in mitochondrial dynamics during ceramide-induced cardiomyocyte early apoptosis. Cardiovasc Res (2007) 1.63
dDOR is an EcR coactivator that forms a feed-forward loop connecting insulin and ecdysone signaling. Curr Biol (2010) 1.62
GLP-1 and changes in glucose tolerance following gastric bypass surgery in morbidly obese subjects. Obes Surg (2006) 1.60
Dominant role of the p110beta isoform of PI3K over p110alpha in energy homeostasis regulation by POMC and AgRP neurons. Cell Metab (2009) 1.59
Macrophages and adipocytes in human obesity: adipose tissue gene expression and insulin sensitivity during calorie restriction and weight stabilization. Diabetes (2009) 1.59
Loss of mitochondrial protease OMA1 alters processing of the GTPase OPA1 and causes obesity and defective thermogenesis in mice. EMBO J (2012) 1.58
Deletion of the von Hippel-Lindau gene in pancreatic beta cells impairs glucose homeostasis in mice. J Clin Invest (2008) 1.56
Mitochondrial fusion is increased by the nuclear coactivator PGC-1beta. PLoS One (2008) 1.50
Histone demethylase LSD1 regulates adipogenesis. J Biol Chem (2010) 1.50
Apelin stimulates glucose utilization in normal and obese insulin-resistant mice. Cell Metab (2008) 1.48
[Organization and functioning model of biomedical research structures. Situation and future challenges]. Med Clin (Barc) (2008) 1.46
Mitochondrial fusion proteins: dual regulators of morphology and metabolism. Semin Cell Dev Biol (2010) 1.44
Subjects with early-onset type 2 diabetes show defective activation of the skeletal muscle PGC-1{alpha}/Mitofusin-2 regulatory pathway in response to physical activity. Diabetes Care (2009) 1.42
Pathophysiology and treatment of cystinuria. Nat Rev Nephrol (2010) 1.40
Insulin stimulates long-chain fatty acid utilization by rat cardiac myocytes through cellular redistribution of FAT/CD36. Diabetes (2002) 1.38
Molecular basis of substrate-induced permeation by an amino acid antiporter. Proc Natl Acad Sci U S A (2011) 1.37
Identification of LAT4, a novel amino acid transporter with system L activity. J Biol Chem (2005) 1.36
The SLC3 and SLC7 families of amino acid transporters. Mol Aspects Med (2013) 1.36
In vivo regulation of human skeletal muscle gene expression by thyroid hormone. Genome Res (2002) 1.33
Role of mitochondrial dynamics proteins in the pathophysiology of obesity and type 2 diabetes. Int J Biochem Cell Biol (2009) 1.32
Natriuretic peptides enhance the oxidative capacity of human skeletal muscle. J Clin Invest (2012) 1.32
Effect of aerobic training on plasma levels and subcutaneous abdominal adipose tissue gene expression of adiponectin, leptin, interleukin 6, and tumor necrosis factor alpha in obese women. Metabolism (2006) 1.31
Caveolin-1 deficiency causes cholesterol-dependent mitochondrial dysfunction and apoptotic susceptibility. Curr Biol (2011) 1.31
PP2A regulatory subunit PP2A-B' counteracts S6K phosphorylation. Cell Metab (2010) 1.29
The role of viruses in the aetiology of community-acquired pneumonia in adults. Antivir Ther (2006) 1.28
Cathepsin S, a novel biomarker of adiposity: relevance to atherogenesis. FASEB J (2005) 1.27
Caveolin-1 loss of function accelerates glucose transporter 4 and insulin receptor degradation in 3T3-L1 adipocytes. Endocrinology (2009) 1.26
Adiponutrin: A new gene regulated by energy balance in human adipose tissue. J Clin Endocrinol Metab (2004) 1.23
Endoplasmic reticulum and the unfolded protein response: dynamics and metabolic integration. Int Rev Cell Mol Biol (2013) 1.23
Histone H3 lysine 4 dimethylation signals the transcriptional competence of the adiponectin promoter in preadipocytes. J Biol Chem (2006) 1.21
Effects of different hypocaloric diets on protein secretion from adipose tissue of obese women. Diabetes (2004) 1.20
Lipolysis is altered in MHC class I zinc-alpha(2)-glycoprotein deficient mice. FEBS Lett (2007) 1.19
The genetics of heteromeric amino acid transporters. Physiology (Bethesda) (2005) 1.18
Localization and functional analyses of the MLC1 protein involved in megalencephalic leukoencephalopathy with subcortical cysts. Hum Mol Genet (2004) 1.18
A role for peroxisome proliferator-activated receptor γ coactivator-1 in the control of mitochondrial dynamics during postnatal cardiac growth. Circ Res (2013) 1.18
Arginine transport via cationic amino acid transporter 2 plays a critical regulatory role in classical or alternative activation of macrophages. J Immunol (2006) 1.15
Slc7a9-deficient mice develop cystinuria non-I and cystine urolithiasis. Hum Mol Genet (2003) 1.15
The nuclear cofactor DOR regulates autophagy in mammalian and Drosophila cells. EMBO Rep (2009) 1.14
Evidence of expression of endotoxin receptors CD14, toll-like receptors TLR4 and TLR2 and associated molecule MD-2 and of sensitivity to endotoxin (LPS) in islet beta cells. Clin Exp Immunol (2003) 1.13
Impact on fatty acid metabolism and differential localization of FATP1 and FAT/CD36 proteins delivered in cultured human muscle cells. Am J Physiol Cell Physiol (2005) 1.13
CD14 modulates inflammation-driven insulin resistance. Diabetes (2011) 1.11
Functional and structural characterization of the first prokaryotic member of the L-amino acid transporter (LAT) family: a model for APC transporters. J Biol Chem (2007) 1.11
rBAT-b(0,+)AT heterodimer is the main apical reabsorption system for cystine in the kidney. Am J Physiol Renal Physiol (2002) 1.11
Induction of pancreatic islet cell differentiation by the neurogenin-neuroD cascade. Differentiation (2007) 1.09