Genomic targets of the human c-Myc protein.

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature (2007) 75.09

An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors. Nat Genet (2008) 17.67

An extended transcriptional network for pluripotency of embryonic stem cells. Cell (2008) 14.64

ARACNE: an algorithm for the reconstruction of gene regulatory networks in a mammalian cellular context. BMC Bioinformatics (2006) 14.49

Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming. Cell (2008) 14.17

ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia. Genome Res (2012) 9.13

MYC on the path to cancer. Cell (2012) 8.65

Transcriptional amplification in tumor cells with elevated c-Myc. Cell (2012) 8.24

Myc's broad reach. Genes Dev (2008) 7.56

Unbiased location analysis of E2F1-binding sites suggests a widespread role for E2F1 in the human genome. Genome Res (2006) 6.54

HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity. Cancer Cell (2007) 6.16

MicroRNAs in cell proliferation, cell death, and tumorigenesis. Br J Cancer (2006) 5.37

Global mapping of c-Myc binding sites and target gene networks in human B cells. Proc Natl Acad Sci U S A (2006) 5.27

miR-24 Inhibits cell proliferation by targeting E2F2, MYC, and other cell-cycle genes via binding to "seedless" 3'UTR microRNA recognition elements. Mol Cell (2009) 5.22

Myc stimulates nuclearly encoded mitochondrial genes and mitochondrial biogenesis. Mol Cell Biol (2005) 4.99

Myc influences global chromatin structure. EMBO J (2006) 4.71

Genomic binding by the Drosophila Myc, Max, Mad/Mnt transcription factor network. Genes Dev (2003) 4.68

An integrated database of genes responsive to the Myc oncogenic transcription factor: identification of direct genomic targets. Genome Biol (2003) 4.49

MYC-induced cancer cell energy metabolism and therapeutic opportunities. Clin Cancer Res (2009) 4.32

An initial blueprint for myogenic differentiation. Genes Dev (2005) 4.22

Distinct thresholds govern Myc's biological output in vivo. Cancer Cell (2008) 4.16

Identification of the miR-106b~25 microRNA cluster as a proto-oncogenic PTEN-targeting intron that cooperates with its host gene MCM7 in transformation. Sci Signal (2010) 4.15

Genetic regulators of large-scale transcriptional signatures in cancer. Nat Genet (2006) 3.96

MYC as a regulator of ribosome biogenesis and protein synthesis. Nat Rev Cancer (2010) 3.64

Genome-wide analysis of repressor element 1 silencing transcription factor/neuron-restrictive silencing factor (REST/NRSF) target genes. Proc Natl Acad Sci U S A (2004) 3.39

Cellular senescence is an important mechanism of tumor regression upon c-Myc inactivation. Proc Natl Acad Sci U S A (2007) 3.37

MYC recruits the TIP60 histone acetyltransferase complex to chromatin. EMBO Rep (2003) 3.24

MAPPER: a search engine for the computational identification of putative transcription factor binding sites in multiple genomes. BMC Bioinformatics (2005) 3.23

PUMA, a potent killer with or without p53. Oncogene (2008) 3.09

Rapid loss of intestinal crypts upon conditional deletion of the Wnt/Tcf-4 target gene c-Myc. Mol Cell Biol (2006) 2.83

MicroRNA: Biogenesis, Function and Role in Cancer. Curr Genomics (2010) 2.80

Distinct mammalian SWI/SNF chromatin remodeling complexes with opposing roles in cell-cycle control. EMBO J (2007) 2.75

TRED: a Transcriptional Regulatory Element Database and a platform for in silico gene regulation studies. Nucleic Acids Res (2005) 2.73

The cell cycle and Myc intersect with mechanisms that regulate pluripotency and reprogramming. Cell Stem Cell (2009) 2.72

The Trithorax group protein Lid is a trimethyl histone H3K4 demethylase required for dMyc-induced cell growth. Genes Dev (2007) 2.57

The role of heat shock transcription factor 1 in the genome-wide regulation of the mammalian heat shock response. Mol Biol Cell (2003) 2.56

Stat3 and c-Myc genome-wide promoter occupancy in embryonic stem cells. PLoS One (2008) 2.51

Selective transcriptional regulation by Myc in cellular growth control and lymphomagenesis. Nature (2014) 2.38

mSin3A corepressor regulates diverse transcriptional networks governing normal and neoplastic growth and survival. Genes Dev (2005) 2.37

Pro-proliferative FoxM1 is a target of p53-mediated repression. Oncogene (2009) 2.32

The HECT-domain ubiquitin ligase Huwe1 controls neural differentiation and proliferation by destabilizing the N-Myc oncoprotein. Nat Cell Biol (2008) 2.32

A core MYC gene expression signature is prominent in basal-like breast cancer but only partially overlaps the core serum response. PLoS One (2009) 2.29

For better or for worse: the role of Pim oncogenes in tumorigenesis. Nat Rev Cancer (2010) 2.26

Myc-induced proliferation and transformation require Akt-mediated phosphorylation of FoxO proteins. EMBO J (2004) 2.19

Evaluation of myc E-box phylogenetic footprints in glycolytic genes by chromatin immunoprecipitation assays. Mol Cell Biol (2004) 2.19

The p53 regulatory gene MDM2 is a direct transcriptional target of MYCN in neuroblastoma. Proc Natl Acad Sci U S A (2005) 2.19

Global regulation of nucleotide biosynthetic genes by c-Myc. PLoS One (2008) 2.12

Global identification of Myc target genes reveals its direct role in mitochondrial biogenesis and its E-box usage in vivo. PLoS One (2008) 2.12

Reduced c-Myc signaling triggers telomere-independent senescence by regulating Bmi-1 and p16(INK4a). Proc Natl Acad Sci U S A (2006) 2.06

Activation of transferrin receptor 1 by c-Myc enhances cellular proliferation and tumorigenesis. Mol Cell Biol (2006) 2.01

Genome-wide transcription factor binding: beyond direct target regulation. Trends Genet (2011) 1.97

Induction of Mxi1-SR alpha by FOXO3a contributes to repression of Myc-dependent gene expression. Mol Cell Biol (2007) 1.96

Metastasis-associated protein 1 (MTA1) is an essential downstream effector of the c-MYC oncoprotein. Proc Natl Acad Sci U S A (2005) 1.91

Direct repression of FLIP expression by c-myc is a major determinant of TRAIL sensitivity. Mol Cell Biol (2004) 1.90

Genomic analysis of estrogen cascade reveals histone variant H2A.Z associated with breast cancer progression. Mol Syst Biol (2008) 1.89

Myc proteins as therapeutic targets. Oncogene (2010) 1.88

Identification of a cholangiocarcinoma-like gene expression trait in hepatocellular carcinoma. Cancer Res (2010) 1.82

Pluripotency and nuclear reprogramming. Philos Trans R Soc Lond B Biol Sci (2008) 1.82

A role for c-Myc in the regulation of ribosomal RNA processing. Nucleic Acids Res (2003) 1.80

MicroRNAs in gene regulation: when the smallest governs it all. J Biomed Biotechnol (2006) 1.76

The Myc transactivation domain promotes global phosphorylation of the RNA polymerase II carboxy-terminal domain independently of direct DNA binding. Mol Cell Biol (2007) 1.75

The role of supercoiling in transcriptional control of MYC and its importance in molecular therapeutics. Nat Rev Cancer (2009) 1.71

Translational control in cancer etiology. Cold Spring Harb Perspect Biol (2013) 1.71

Mammalian WDR12 is a novel member of the Pes1-Bop1 complex and is required for ribosome biogenesis and cell proliferation. J Cell Biol (2005) 1.69

Chromatin remodeling finds its place in the DNA double-strand break response. Nucleic Acids Res (2009) 1.66

Integrated biochemical and computational approach identifies BCL6 direct target genes controlling multiple pathways in normal germinal center B cells. Blood (2009) 1.64

c-Myc and cancer metabolism. Clin Cancer Res (2012) 1.60

Analysis of Myc-induced histone modifications on target chromatin. PLoS One (2008) 1.59

Genomic and proteomic analysis reveals a threshold level of MYC required for tumor maintenance. Cancer Res (2008) 1.58

An overview of MYC and its interactome. Cold Spring Harb Perspect Med (2014) 1.53

Cell-type independent MYC target genes reveal a primordial signature involved in biomass accumulation. PLoS One (2011) 1.53

N-Myc regulates a widespread euchromatic program in the human genome partially independent of its role as a classical transcription factor. Cancer Res (2008) 1.52

Id2 mediates tumor initiation, proliferation, and angiogenesis in Rb mutant mice. Mol Cell Biol (2005) 1.50

hnRNP K binds a core polypyrimidine element in the eukaryotic translation initiation factor 4E (eIF4E) promoter, and its regulation of eIF4E contributes to neoplastic transformation. Mol Cell Biol (2005) 1.50

MYC: connecting selective transcriptional control to global RNA production. Nat Rev Cancer (2015) 1.47

Epidermal stem cells are defined by global histone modifications that are altered by Myc-induced differentiation. PLoS One (2007) 1.45

"Myc'ed messages": myc induces transcription of E2F1 while inhibiting its translation via a microRNA polycistron. PLoS Genet (2007) 1.45

Whole-genome analysis reveals a strong positional bias of conserved dMyc-dependent E-boxes. Mol Cell Biol (2005) 1.44

c-Myc induces chromosomal rearrangements through telomere and chromosome remodeling in the interphase nucleus. Proc Natl Acad Sci U S A (2005) 1.43

In vivo transcriptional regulation of N-Myc target genes is controlled by E-box methylation. Proc Natl Acad Sci U S A (2005) 1.43

Stress response gene ATF3 is a target of c-myc in serum-induced cell proliferation. EMBO J (2005) 1.41

Nuclear receptor hepatocyte nuclear factor 4alpha1 competes with oncoprotein c-Myc for control of the p21/WAF1 promoter. Mol Endocrinol (2007) 1.40

c-Myc mediates pre-TCR-induced proliferation but not developmental progression. Blood (2006) 1.39

TRRAP and GCN5 are used by c-Myc to activate RNA polymerase III transcription. Proc Natl Acad Sci U S A (2007) 1.39

Novel c-MYC target genes mediate differential effects on cell proliferation and migration. EMBO Rep (2006) 1.39

The cancerous translation apparatus. Curr Opin Genet Dev (2011) 1.38

Cdx1 and c-Myc foster the initiation of transdifferentiation of the normal esophageal squamous epithelium toward Barrett's esophagus. PLoS One (2008) 1.34

Genome-wide mapping of Myc binding and gene regulation in serum-stimulated fibroblasts. Oncogene (2011) 1.34

High-level IGF1R expression is required for leukemia-initiating cell activity in T-ALL and is supported by Notch signaling. J Exp Med (2011) 1.31

Activation of Ras/PI3K/ERK pathway induces c-Myc stabilization to upregulate argininosuccinate synthetase, leading to arginine deiminase resistance in melanoma cells. Cancer Res (2012) 1.29

Androgen receptor promotes ligand-independent prostate cancer progression through c-Myc upregulation. PLoS One (2013) 1.29

Myc regulates the transcription of the PRC2 gene to control the expression of developmental genes in embryonic stem cells. Mol Cell Biol (2011) 1.28

The circadian clock in cancer development and therapy. Prog Mol Biol Transl Sci (2013) 1.28

Mnt-Max to Myc-Max complex switching regulates cell cycle entry. J Cell Biol (2005) 1.25

Prediction and preliminary validation of oncogene regulation by miRNAs. BMC Mol Biol (2007) 1.23

N-Myc regulates expression of pluripotency genes in neuroblastoma including lif, klf2, klf4, and lin28b. PLoS One (2009) 1.23

Combined analysis of murine and human microarrays and ChIP analysis reveals genes associated with the ability of MYC to maintain tumorigenesis. PLoS Genet (2008) 1.23

Effects of nickel, chromate, and arsenite on histone 3 lysine methylation. Toxicol Appl Pharmacol (2009) 1.23

Improved prognostic classification of breast cancer defined by antagonistic activation patterns of immune response pathway modules. BMC Cancer (2010) 1.22

Identification of novel Myc target genes with a potential role in lymphomagenesis. Nucleic Acids Res (2004) 1.20

Genome-wide location and function of DNA binding proteins. Science (2000) 31.25

The fundamental role of epigenetic events in cancer. Nat Rev Genet (2002) 30.05

CpG islands in vertebrate genomes. J Mol Biol (1987) 23.16

Genomic binding sites of the yeast cell-cycle transcription factors SBF and MBF. Nature (2001) 21.55

Promoter-specific binding of Rap1 revealed by genome-wide maps of protein-DNA association. Nat Genet (2001) 13.05

Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc. Science (1991) 12.00

E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints. Genes Dev (2002) 10.06

The Myc/Max/Mad network and the transcriptional control of cell behavior. Annu Rev Cell Dev Biol (2000) 8.47

Serial regulation of transcriptional regulators in the yeast cell cycle. Cell (2001) 7.99

Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis. Genes Dev (2002) 6.74

Binding of c-Myc to chromatin mediates mitogen-induced acetylation of histone H4 and gene activation. Genes Dev (2001) 6.36

Epigenetic codes for heterochromatin formation and silencing: rounding up the usual suspects. Cell (2002) 6.25

Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor. Science (2002) 6.05

Association of Myn, the murine homolog of max, with c-Myc stimulates methylation-sensitive DNA binding and ras cotransformation. Cell (1991) 5.76

Drosophila myc regulates cellular growth during development. Cell (1999) 5.66

Suppression of Myc-induced apoptosis in beta cells exposes multiple oncogenic properties of Myc and triggers carcinogenic progression. Cell (2002) 5.29

Phenotypes of c-Myc-deficient rat fibroblasts isolated by targeted homologous recombination. Cell Growth Differ (1997) 5.14

Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN. Nat Med (2000) 5.04

Genomic binding by the Drosophila Myc, Max, Mad/Mnt transcription factor network. Genes Dev (2003) 4.68

Proteins of the Myc network: essential regulators of cell growth and differentiation. Adv Cancer Res (1996) 4.48

c-Myc regulates mammalian body size by controlling cell number but not cell size. Nature (2001) 4.46

Reversible activation of c-Myc in skin: induction of a complex neoplastic phenotype by a single oncogenic lesion. Mol Cell (1999) 4.38

A comparison of the Celera and Ensembl predicted gene sets reveals little overlap in novel genes. Cell (2001) 4.36

Myc and Max proteins possess distinct transcriptional activities. Nature (1992) 4.16

Analysis of C-MYC function in normal cells via conditional gene-targeted mutation. Immunity (2001) 4.09

The transcriptional program of a human B cell line in response to Myc. Nucleic Acids Res (2001) 4.08

The myc oncogene: MarvelouslY Complex. Adv Cancer Res (2002) 3.68

Characterization of the c-MYC-regulated transcriptome by SAGE: identification and analysis of c-MYC target genes. Proc Natl Acad Sci U S A (2002) 3.55

Transcriptional activation by the human c-Myc oncoprotein in yeast requires interaction with Max. Nature (1992) 3.43

Acetylation of histone H4 plays a primary role in enhancing transcription factor binding to nucleosomal DNA in vitro. EMBO J (1996) 3.25

Regulation of cyclin D2 gene expression by the Myc/Max/Mad network: Myc-dependent TRRAP recruitment and histone acetylation at the cyclin D2 promoter. Genes Dev (2001) 3.15

Automated gene identification in large-scale genomic sequences. J Comput Biol (1997) 3.14

Myc and the cell cycle. Front Biosci (1998) 2.88

A large scale genetic analysis of c-Myc-regulated gene expression patterns. J Biol Chem (2003) 2.69

Myc versus USF: discrimination at the cad gene is determined by core promoter elements. Mol Cell Biol (1997) 2.62

c-MYC apoptotic function is mediated by NRF-1 target genes. Genes Dev (2003) 2.51

Switch from Myc/Max to Mad1/Max binding and decrease in histone acetylation at the telomerase reverse transcriptase promoter during differentiation of HL60 cells. Proc Natl Acad Sci U S A (2001) 2.33

Myc induces the nucleolin and BN51 genes: possible implications in ribosome biogenesis. Nucleic Acids Res (2000) 2.23

Gene-target recognition among members of the myc superfamily and implications for oncogenesis. Nat Genet (2000) 2.19

Identifying genes regulated in a Myc-dependent manner. J Biol Chem (2002) 1.98

Bax loss impairs Myc-induced apoptosis and circumvents the selection of p53 mutations during Myc-mediated lymphomagenesis. Mol Cell Biol (2001) 1.96

Characterization of nucleophosmin (B23) as a Myc target by scanning chromatin immunoprecipitation. J Biol Chem (2001) 1.89

TRRAP-dependent and TRRAP-independent transcriptional activation by Myc family oncoproteins. Mol Cell Biol (2002) 1.80

Analyses of p53 target genes in the human genome by bioinformatic and microarray approaches. J Biol Chem (2001) 1.73

c-myc protein expression in untransformed fibroblasts. Oncogene (1991) 1.72

Defining the specific physiological requirements for c-Myc in T cell development. Nat Immunol (2001) 1.65

Angiogenesis is an early event in the generation of myc-induced lymphomas. Oncogene (2000) 1.61

An in vivo function for the transforming Myc protein: elicitation of the angiogenic phenotype. Cell Growth Differ (2000) 1.54

Serum- and polypeptide growth factor-inducible gene expression in mouse fibroblasts. Prog Nucleic Acid Res Mol Biol (1998) 1.54

Distinct DNA binding preferences for the c-Myc/Max and Max/Max dimers. Nucleic Acids Res (1993) 1.53

The c-myc oncogene in tumor progression. Crit Rev Oncog (1993) 1.32

A DNA microarray screen for genes involved in c-MYC and N-MYC oncogenesis in human tumors. Oncogene (2001) 1.31

Role of N-myc in the developing mouse kidney. Dev Biol (2000) 1.05

Niemann-Pick C1 Like 1 protein is critical for intestinal cholesterol absorption. Science (2004) 6.19

Myc-binding-site recognition in the human genome is determined by chromatin context. Nat Cell Biol (2006) 4.71

Methylation of histone H3R2 by PRMT6 and H3K4 by an MLL complex are mutually exclusive. Nature (2007) 3.68

E2F target genes: unraveling the biology. Trends Biochem Sci (2004) 3.49

MYC recruits the TIP60 histone acetyltransferase complex to chromatin. EMBO Rep (2003) 3.24

Human survivin is negatively regulated by wild-type p53 and participates in p53-dependent apoptotic pathway. Oncogene (2002) 3.12

Myc represses transcription through recruitment of DNA methyltransferase corepressor. EMBO J (2004) 2.94

Tip60 in DNA damage response and growth control: many tricks in one HAT. Trends Cell Biol (2006) 2.68

The replication checkpoint protects fork stability by releasing transcribed genes from nuclear pores. Cell (2011) 2.65

Tip60 is a haplo-insufficient tumour suppressor required for an oncogene-induced DNA damage response. Nature (2007) 2.54

Topoisomerase I poisoning results in PARP-mediated replication fork reversal. Nat Struct Mol Biol (2012) 2.44

Cyclins E1 and E2 are required for endoreplication in placental trophoblast giant cells. EMBO J (2003) 2.34

RSK is a principal effector of the RAS-ERK pathway for eliciting a coordinate promotile/invasive gene program and phenotype in epithelial cells. Mol Cell (2009) 2.11

Cdk2 suppresses cellular senescence induced by the c-myc oncogene. Nat Cell Biol (2009) 1.99

E2F-dependent histone acetylation and recruitment of the Tip60 acetyltransferase complex to chromatin in late G1. Mol Cell Biol (2004) 1.85

Werner syndrome protein limits MYC-induced cellular senescence. Genes Dev (2003) 1.84

Global transcriptional program of p53 target genes during the process of apoptosis and cell cycle progression. Oncogene (2003) 1.79

Replication termination at eukaryotic chromosomes is mediated by Top2 and occurs at genomic loci containing pausing elements. Mol Cell (2010) 1.74

The recycling and transcytotic pathways for IgG transport by FcRn are distinct and display an inherent polarity. J Cell Biol (2009) 1.68

Epigenome microarray platform for proteome-wide dissection of chromatin-signaling networks. PLoS One (2009) 1.66

Symmetric dimethylation of H3R2 is a newly identified histone mark that supports euchromatin maintenance. Nat Struct Mol Biol (2012) 1.64

Analysis of Myc-induced histone modifications on target chromatin. PLoS One (2008) 1.59

Gene expression profiles and transcription factors involved in parathyroid hormone signaling in osteoblasts revealed by microarray and bioinformatics. J Biol Chem (2003) 1.53

Senataxin associates with replication forks to protect fork integrity across RNA-polymerase-II-transcribed genes. Cell (2012) 1.51

Genome-organizing factors Top2 and Hmo1 prevent chromosome fragility at sites of S phase transcription. Cell (2009) 1.48

Nucleophosmin and its AML-associated mutant regulate c-Myc turnover through Fbw7 gamma. J Cell Biol (2008) 1.41

Transcriptional regulation during p21WAF1/CIP1-induced apoptosis in human ovarian cancer cells. J Biol Chem (2002) 1.38

Genetic strategies for antibacterial drug discovery. Nat Rev Genet (2003) 1.30

Identification and characterization of a novel RF-amide peptide ligand for orphan G-protein-coupled receptor SP9155. J Biol Chem (2003) 1.29

Human members of the eukaryotic protein kinase family. Genome Biol (2002) 1.25

Deacetylase activity is required for recruitment of the basal transcription machinery and transactivation by STAT5. Mol Cell Biol (2003) 1.24

Microarray profile of differentially expressed genes in a monkey model of allergic asthma. Genome Biol (2002) 1.20

Transforming growth factor-beta 2 is a transcriptional target for Akt/protein kinase B via forkhead transcription factor. J Biol Chem (2002) 1.13

Genome recognition by MYC. Cold Spring Harb Perspect Med (2014) 1.10

RSSsite: a reference database and prediction tool for the identification of cryptic Recombination Signal Sequences in human and murine genomes. Nucleic Acids Res (2010) 1.07

Identification of HCV protease inhibitor resistance mutations by selection pressure-based method. Nucleic Acids Res (2009) 1.07

The methyltransferase Set7/9 (Setd7) is dispensable for the p53-mediated DNA damage response in vivo. Mol Cell (2011) 1.06

RNA interference targeting of A1 receptor-overexpressing breast carcinoma cells leads to diminished rates of cell proliferation and induction of apoptosis. Cancer Biol Ther (2005) 1.00

Analysis of a human brain transcriptome map. BMC Genomics (2002) 0.99

Impairment of cytoplasmic eIF6 activity restricts lymphomagenesis and tumor progression without affecting normal growth. Cancer Cell (2011) 0.98

Quantification of single nucleotide polymorphisms by automated DNA sequencing. Biochem Biophys Res Commun (2003) 0.96

Two sides of the Myc-induced DNA damage response: from tumor suppression to tumor maintenance. Cell Div (2012) 0.93

Integrative genomics revealed RAI3 is a cell growth-promoting gene and a novel P53 transcriptional target. J Biol Chem (2005) 0.90

Hepatitis C virus whole genome position weight matrix and robust primer design. BMC Microbiol (2002) 0.90

Analysis of the ERK1,2 transcriptome in mammary epithelial cells. Biochem J (2004) 0.90

Immortalization of human neural stem cells with the c-myc mutant T58A. PLoS One (2008) 0.89

Computational analysis of composite regulatory elements. Mamm Genome (2002) 0.89

Genome wide in silico SNP-tumor association analysis. BMC Cancer (2004) 0.89

Comparative promoter analysis and its application in analysis of PTH-regulated gene expression. J Mol Biol (2003) 0.88

A novel shape-feature based approach to virtual library screening. J Chem Inf Comput Sci (2002) 0.88

Quality of life, optimism/pessimism, and knowledge and attitudes toward HIV Screening among pregnant women in Ghana. Womens Health Issues (2008) 0.86

Abrogation of junctional adhesion molecule-A expression induces cell apoptosis and reduces breast cancer progression. PLoS One (2011) 0.86

A non-redundant function of cyclin E1 in hematopoietic stem cells. Cell Cycle (2013) 0.86

Myc, Cdk2 and cellular senescence: Old players, new game. Cell Cycle (2010) 0.86

The FlexX database docking environment--rational extraction of receptor based pharmacophores. Curr Drug Discov Technol (2004) 0.85

Mechanism of azole antifungal activity as determined by liquid chromatographic/mass spectrometric monitoring of ergosterol biosynthesis. J Mass Spectrom (2002) 0.83

Relationship between genome and epigenome--challenges and requirements for future research. BMC Genomics (2014) 0.82

Using ensembles to classify compounds for drug discovery. J Chem Inf Comput Sci (2003) 0.82

MYC degradation: deubiquitinating enzymes enter the dance. Nat Cell Biol (2007) 0.82

The use of direct cDNA selection to rapidly and effectively identify genes in the fungus Aspergillus fumigatus. Fungal Genet Biol (2002) 0.79

TGFβ-dependent gene expression shows that senescence correlates with abortive differentiation along several lineages in Myc-induced lymphomas. Cell Cycle (2010) 0.78

Identification of differentially expressed genes in a monkey model of allergic asthma by microarray technology. Chest (2002) 0.78

Generation of p53 target database via integration of microarray and global p53 DNA-binding site analysis. Methods Mol Biol (2004) 0.78

Chromatin association and regulation of rDNA transcription by the Ras-family protein RasL11a. EMBO J (2010) 0.78

Identification of a new mechanism for targeting myosin II heavy chain phosphorylation by Dictyostelium myosin heavy chain kinase B. BMC Res Notes (2010) 0.77

A snapshot of the physical and functional wiring of the Eps15 homology domain network in the nematode. PLoS One (2013) 0.77

Domain-oriented functional analysis based on expression profiling. BMC Genomics (2002) 0.77

Optimism/pessimism and health-related quality of life during pregnancy across three continents: a matched cohort study in China, Ghana, and the United States. BMC Pregnancy Childbirth (2009) 0.77

A reference database for tumor-related genes co-expressed with interleukin-8 using genome-scale in silico analysis. BMC Genomics (2002) 0.77

Small molecule antagonists of the CCR2b receptor. Part 2: Discovery process and initial structure-activity relationships of diamine derivatives. Bioorg Med Chem Lett (2004) 0.75

Small molecule inhibitors of the CCR2b receptor. Part 1: Discovery and optimization of homopiperazine derivatives. Bioorg Med Chem Lett (2004) 0.75