Published in Kidney Int on June 01, 2003
Contemporary epidemiology of renal cell cancer. Cancer J (2008) 2.40
Conditional ablation of macrophages halts progression of crescentic glomerulonephritis. Am J Pathol (2005) 2.38
Chemistry and antihypertensive effects of tempol and other nitroxides. Pharmacol Rev (2008) 1.91
Serum uric acid predicts vascular complications in adults with type 1 diabetes: the coronary artery calcification in type 1 diabetes study. Acta Diabetol (2014) 1.48
Oxidative stress in hypertension: role of the kidney. Antioxid Redox Signal (2013) 1.13
Addition of endothelial progenitor cells to renal revascularization restores medullary tubular oxygen consumption in swine renal artery stenosis. Am J Physiol Renal Physiol (2012) 1.03
Nitric oxide is an important mediator of renal tubular epithelial cell death in vitro and in murine experimental hydronephrosis. Am J Pathol (2006) 0.99
Inhibition of COX 1 and 2 prior to renal ischemia/reperfusion injury decreases the development of fibrosis. Mol Med (2008) 0.94
Correlations of tissue macrophages and cytoskeletal protein expression with renal fibrosis in patients with diabetes mellitus. Clin Exp Nephrol (2006) 0.93
Prevalence of chronic kidney disease and associated factors among the Chinese population in Taian, China. BMC Nephrol (2014) 0.90
Uric acid and cardiovascular risk. N Engl J Med (2008) 12.20
VEGF inhibition and renal thrombotic microangiopathy. N Engl J Med (2008) 9.87
Bardoxolone methyl in type 2 diabetes and stage 4 chronic kidney disease. N Engl J Med (2013) 7.54
Effect of allopurinol on blood pressure of adolescents with newly diagnosed essential hypertension: a randomized trial. JAMA (2008) 5.59
Hyperuricemia induces endothelial dysfunction. Kidney Int (2005) 5.36
A causal role for uric acid in fructose-induced metabolic syndrome. Am J Physiol Renal Physiol (2005) 4.95
A role for uric acid in the progression of renal disease. J Am Soc Nephrol (2002) 3.77
Increased fructose consumption is associated with fibrosis severity in patients with nonalcoholic fatty liver disease. Hepatology (2010) 3.73
Uric acid-induced C-reactive protein expression: implication on cell proliferation and nitric oxide production of human vascular cells. J Am Soc Nephrol (2005) 3.73
Uric acid stimulates monocyte chemoattractant protein-1 production in vascular smooth muscle cells via mitogen-activated protein kinase and cyclooxygenase-2. Hypertension (2003) 3.39
Hyperuricemia induces a primary renal arteriolopathy in rats by a blood pressure-independent mechanism. Am J Physiol Renal Physiol (2002) 3.37
Fructose consumption as a risk factor for non-alcoholic fatty liver disease. J Hepatol (2008) 3.33
Evolving importance of kidney disease: from subspecialty to global health burden. Lancet (2013) 3.30
Diabetic endothelial nitric oxide synthase knockout mice develop advanced diabetic nephropathy. J Am Soc Nephrol (2007) 3.08
IL-10, IL-6, and TNF-alpha: central factors in the altered cytokine network of uremia--the good, the bad, and the ugly. Kidney Int (2005) 2.78
Adverse effects of the classic antioxidant uric acid in adipocytes: NADPH oxidase-mediated oxidative/nitrosative stress. Am J Physiol Cell Physiol (2007) 2.71
Ketohexokinase-dependent metabolism of fructose induces proinflammatory mediators in proximal tubular cells. J Am Soc Nephrol (2009) 2.70
Circulating biomarkers of inflammation, antioxidant activity, and platelet activation are associated with primary combustion aerosols in subjects with coronary artery disease. Environ Health Perspect (2008) 2.59
Role of the microvascular endothelium in progressive renal disease. J Am Soc Nephrol (2002) 2.51
Uric acid, hominoid evolution, and the pathogenesis of salt-sensitivity. Hypertension (2002) 2.47
Urinary CD80 is elevated in minimal change disease but not in focal segmental glomerulosclerosis. Kidney Int (2010) 2.47
Hyperuricemia in childhood primary hypertension. Hypertension (2003) 2.39
Serum uric acid, inflammation, and nondipping circadian pattern in essential hypertension. J Clin Hypertens (Greenwich) (2012) 2.37
Endogenous fructose production and metabolism in the liver contributes to the development of metabolic syndrome. Nat Commun (2013) 2.29
Fructose-induced leptin resistance exacerbates weight gain in response to subsequent high-fat feeding. Am J Physiol Regul Integr Comp Physiol (2008) 2.28
Hypothesis: fructose-induced hyperuricemia as a causal mechanism for the epidemic of the metabolic syndrome. Nat Clin Pract Nephrol (2005) 2.24
Thiazide diuretics exacerbate fructose-induced metabolic syndrome. J Am Soc Nephrol (2007) 2.24
Inhibition of renal fibrosis by gene transfer of inducible Smad7 using ultrasound-microbubble system in rat UUO model. J Am Soc Nephrol (2003) 2.24
Contribution of impaired Nrf2-Keap1 pathway to oxidative stress and inflammation in chronic renal failure. Am J Physiol Renal Physiol (2009) 2.08
Air pollution exposures and circulating biomarkers of effect in a susceptible population: clues to potential causal component mixtures and mechanisms. Environ Health Perspect (2009) 2.06
Endothelial dysfunction: a link among preeclampsia, recurrent pregnancy loss, and future cardiovascular events? Hypertension (2006) 2.02
Mild hyperuricemia induces vasoconstriction and maintains glomerular hypertension in normal and remnant kidney rats. Kidney Int (2005) 2.02
Increased fructose associates with elevated blood pressure. J Am Soc Nephrol (2010) 2.01
Effect of a short-term diet and exercise intervention on oxidative stress, inflammation, MMP-9, and monocyte chemotactic activity in men with metabolic syndrome factors. J Appl Physiol (1985) (2005) 1.96
TGF-beta induces proangiogenic and antiangiogenic factors via parallel but distinct Smad pathways. Kidney Int (2004) 1.95
Fructose-induced metabolic syndrome is associated with glomerular hypertension and renal microvascular damage in rats. Am J Physiol Renal Physiol (2006) 1.94
Advanced glycation end products activate Smad signaling via TGF-beta-dependent and independent mechanisms: implications for diabetic renal and vascular disease. FASEB J (2003) 1.93
Targeting the transcription factor Nrf2 to ameliorate oxidative stress and inflammation in chronic kidney disease. Kidney Int (2013) 1.93
Reduction of renal immune cell infiltration results in blood pressure control in genetically hypertensive rats. Am J Physiol Renal Physiol (2002) 1.89
J-shaped mortality relationship for uric acid in CKD. Am J Kidney Dis (2006) 1.88
Smad7 inhibits fibrotic effect of TGF-Beta on renal tubular epithelial cells by blocking Smad2 activation. J Am Soc Nephrol (2002) 1.86
The aging kidney. Kidney Int (2008) 1.85
Obstructive uropathy in mice and humans: potential role for PDGF-D in the progression of tubulointerstitial injury. J Am Soc Nephrol (2003) 1.84
Human vascular smooth muscle cells express a urate transporter. J Am Soc Nephrol (2006) 1.83
CD80 and suPAR in patients with minimal change disease and focal segmental glomerulosclerosis: diagnostic and pathogenic significance. Pediatr Nephrol (2013) 1.83
Hyperuricemia as a mediator of the proinflammatory endocrine imbalance in the adipose tissue in a murine model of the metabolic syndrome. Diabetes (2011) 1.82
Role of uric acid in hypertension, renal disease, and metabolic syndrome. Cleve Clin J Med (2006) 1.81
Oxidative stress with an activation of the renin-angiotensin system in human vascular endothelial cells as a novel mechanism of uric acid-induced endothelial dysfunction. J Hypertens (2010) 1.80
Renal mass reduction results in accumulation of lipids and dysregulation of lipid regulatory proteins in the remnant kidney. Am J Physiol Renal Physiol (2009) 1.78
Uric acid: the oxidant-antioxidant paradox. Nucleosides Nucleotides Nucleic Acids (2008) 1.76
Serum uric acid as a predictor for development of diabetic nephropathy in type 1 diabetes: an inception cohort study. Diabetes (2009) 1.76
Oxidative stress, renal infiltration of immune cells, and salt-sensitive hypertension: all for one and one for all. Am J Physiol Renal Physiol (2004) 1.76
Renal angiotensin II concentration and interstitial infiltration of immune cells are correlated with blood pressure levels in salt-sensitive hypertension. Am J Physiol Regul Integr Comp Physiol (2007) 1.74
Oxidative stress and dysregulation of NAD(P)H oxidase and antioxidant enzymes in diet-induced metabolic syndrome. Metabolism (2006) 1.74
Opposing effects of fructokinase C and A isoforms on fructose-induced metabolic syndrome in mice. Proc Natl Acad Sci U S A (2012) 1.72
The green tea polyphenol (-)-epigallocatechin-3-gallate ameliorates experimental immune-mediated glomerulonephritis. Kidney Int (2011) 1.72
Urinary CD80 excretion increases in idiopathic minimal-change disease. J Am Soc Nephrol (2008) 1.72
Pathophysiological mechanisms of salt-dependent hypertension. Am J Kidney Dis (2007) 1.71
Uric acid, endothelial dysfunction and pre-eclampsia: searching for a pathogenetic link. J Hypertens (2004) 1.71
Uric acid decreases NO production and increases arginase activity in cultured pulmonary artery endothelial cells. Am J Physiol Cell Physiol (2008) 1.69
Molecular physiology of urate transport. Physiology (Bethesda) (2005) 1.69
Effect of lowering uric acid on renal disease in the type 2 diabetic db/db mice. Am J Physiol Renal Physiol (2009) 1.69
Role of oxidative stress in the renal abnormalities induced by experimental hyperuricemia. Am J Physiol Renal Physiol (2008) 1.68
Osteopontin is a critical inhibitor of calcium oxalate crystal formation and retention in renal tubules. J Am Soc Nephrol (2003) 1.68
Uric acid induces hepatic steatosis by generation of mitochondrial oxidative stress: potential role in fructose-dependent and -independent fatty liver. J Biol Chem (2012) 1.67
The conundrum of hyperuricemia, metabolic syndrome, and renal disease. Intern Emerg Med (2008) 1.65
Microvascular disease and its role in the brain and cardiovascular system: a potential role for uric acid as a cardiorenal toxin. Nephrol Dial Transplant (2010) 1.65
Downregulation of the renal and hepatic hydrogen sulfide (H2S)-producing enzymes and capacity in chronic kidney disease. Nephrol Dial Transplant (2011) 1.65
Fructose, but not dextrose, accelerates the progression of chronic kidney disease. Am J Physiol Renal Physiol (2007) 1.65
Mild hyperuricemia induces glomerular hypertension in normal rats. Am J Physiol Renal Physiol (2002) 1.64
Systemic inflammation, metabolic syndrome and progressive renal disease. Nephrol Dial Transplant (2009) 1.63
Inactivation of nitric oxide by uric acid. Nucleosides Nucleotides Nucleic Acids (2008) 1.59
The role of uric acid in the pathogenesis of human cardiovascular disease. Heart (2013) 1.59
Impaired renal function further increases odds of 6-year coronary artery calcification progression in adults with type 1 diabetes: the CACTI study. Diabetes Care (2013) 1.58
Glomerular hemodynamic changes associated with arteriolar lesions and tubulointerstitial inflammation. Kidney Int Suppl (2003) 1.57
Higher dietary fructose is associated with impaired hepatic adenosine triphosphate homeostasis in obese individuals with type 2 diabetes. Hepatology (2012) 1.57
Could uric acid have a role in acute renal failure? Clin J Am Soc Nephrol (2006) 1.56
High-fat and high-sucrose (western) diet induces steatohepatitis that is dependent on fructokinase. Hepatology (2013) 1.56
Prevalence and risk factors associated with chronic kidney disease in an adult population from southern China. Nephrol Dial Transplant (2008) 1.55
Adenosine A(2A) receptor activation prevents progressive kidney fibrosis in a model of immune-associated chronic inflammation. Kidney Int (2011) 1.55
Uric acid, the metabolic syndrome, and renal disease. J Am Soc Nephrol (2006) 1.54
Serum uric acid predicts vascular complications in adults with type 1 diabetes: the coronary artery calcification in type 1 diabetes study. Acta Diabetol (2014) 1.48
Effects of cyclosporine in osteopontin null mice. Kidney Int (2002) 1.47
Fructose induces the inflammatory molecule ICAM-1 in endothelial cells. J Am Soc Nephrol (2008) 1.46
Serum uric acid levels predict the development of albuminuria over 6 years in patients with type 1 diabetes: findings from the Coronary Artery Calcification in Type 1 Diabetes study. Nephrol Dial Transplant (2010) 1.45
Endothelial dysfunction as a potential contributor in diabetic nephropathy. Nat Rev Nephrol (2010) 1.43
Early and sustained inhibition of nuclear factor-kappaB prevents hypertension in spontaneously hypertensive rats. J Pharmacol Exp Ther (2005) 1.43
Hypothesis: Uric acid, nephron number, and the pathogenesis of essential hypertension. Kidney Int (2004) 1.42
IL-10 suppresses chemokines, inflammation, and fibrosis in a model of chronic renal disease. J Am Soc Nephrol (2005) 1.41
Serum uric acid and hypertension in adults: a paradoxical relationship in type 1 diabetes. J Clin Hypertens (Greenwich) (2014) 1.41
Effect of diet and exercise intervention on blood pressure, insulin, oxidative stress, and nitric oxide availability. Circulation (2002) 1.40
A randomized study of allopurinol on endothelial function and estimated glomular filtration rate in asymptomatic hyperuricemic subjects with normal renal function. Clin J Am Soc Nephrol (2011) 1.40
Hyperuricemia causes glomerular hypertrophy in the rat. Am J Nephrol (2002) 1.39
Effects of febuxostat on metabolic and renal alterations in rats with fructose-induced metabolic syndrome. Am J Physiol Renal Physiol (2008) 1.38
Resurrection of uric acid as a causal risk factor in essential hypertension. Hypertension (2004) 1.38
Impaired antioxidant activity of high-density lipoprotein in chronic kidney disease. Transl Res (2008) 1.38
Bardoxolone methyl decreases megalin and activates nrf2 in the kidney. J Am Soc Nephrol (2012) 1.36
Serum uric acid: a risk factor and a target for treatment? J Am Soc Nephrol (2006) 1.35