Published in EMBO J on July 01, 2003
Highly efficient miRNA-mediated reprogramming of mouse and human somatic cells to pluripotency. Cell Stem Cell (2011) 6.11
Interferon-inducible ubiquitin E2, Ubc8, is a conjugating enzyme for protein ISGylation. Mol Cell Biol (2004) 2.70
Histone deacetylases 1 and 2 control the progression of neural precursors to neurons during brain development. Proc Natl Acad Sci U S A (2009) 2.27
Acetylation of Stat1 modulates NF-kappaB activity. Genes Dev (2006) 2.10
Role for histone deacetylase 1 in human tumor cell proliferation. Mol Cell Biol (2007) 2.07
Immunomodulatory effects of deacetylase inhibitors: therapeutic targeting of FOXP3+ regulatory T cells. Nat Rev Drug Discov (2009) 2.00
A phosphorylation-acetylation switch regulates STAT1 signaling. Genes Dev (2009) 1.98
E2s: structurally economical and functionally replete. Biochem J (2011) 1.64
Histone deacetylase 2 is phosphorylated, ubiquitinated, and degraded by cigarette smoke. Am J Respir Cell Mol Biol (2008) 1.64
Histone deacetylases 1 and 2 form a developmental switch that controls excitatory synapse maturation and function. J Neurosci (2009) 1.58
Single-stranded DNA-binding proteins regulate the abundance of LIM domain and LIM domain-binding proteins. Genes Dev (2007) 1.57
Valproic acid (VPA) in patients with refractory advanced cancer: a dose escalating phase I clinical trial. Br J Cancer (2007) 1.52
Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells. Clin Epigenetics (2011) 1.31
The ubiquitin ligase Rnf6 regulates local LIM kinase 1 levels in axonal growth cones. Genes Dev (2005) 1.30
Sorafenib and vorinostat kill colon cancer cells by CD95-dependent and -independent mechanisms. Mol Pharmacol (2009) 1.29
Deacetylases and NF-kappaB in redox regulation of cigarette smoke-induced lung inflammation: epigenetics in pathogenesis of COPD. Antioxid Redox Signal (2008) 1.26
Regulating the regulators: the post-translational code of class I HDAC1 and HDAC2. J Biomed Biotechnol (2010) 1.26
Histone deacetylase 2 is required for chromatin condensation and subsequent enucleation of cultured mouse fetal erythroblasts. Haematologica (2010) 1.25
Histone acetylation and histone deacetylase activity of magnesium valproate in tumor and peripheral blood of patients with cervical cancer. A phase I study. Mol Cancer (2005) 1.24
HDAC up-regulation in early colon field carcinogenesis is involved in cell tumorigenicity through regulation of chromatin structure. PLoS One (2013) 1.21
Regulation of mammalian epithelial differentiation and intestine development by class I histone deacetylases. Mol Cell Biol (2004) 1.19
Curcumin restores corticosteroid function in monocytes exposed to oxidants by maintaining HDAC2. Am J Respir Cell Mol Biol (2008) 1.19
Histone deacetylase inhibition with valproic acid downregulates osteocalcin gene expression in human dental pulp stem cells and osteoblasts: evidence for HDAC2 involvement. Stem Cells (2014) 1.19
Distinct and redundant functions of histone deacetylases HDAC1 and HDAC2 in proliferation and tumorigenesis. Cell Cycle (2011) 1.17
Antineoplastic effects of the DNA methylation inhibitor hydralazine and the histone deacetylase inhibitor valproic acid in cancer cell lines. Cancer Cell Int (2006) 1.15
Histone/protein deacetylases and T-cell immune responses. Blood (2012) 1.14
Regulation of estrogen-dependent transcription by the LIM cofactors CLIM and RLIM in breast cancer. Cancer Res (2009) 1.12
Increased anti-leukemic activity of decitabine via AR-42-induced upregulation of miR-29b: a novel epigenetic-targeting approach in acute myeloid leukemia. Leukemia (2012) 1.11
Histone deacetylases control neurogenesis in embryonic brain by inhibition of BMP2/4 signaling. PLoS One (2008) 1.10
Epigenetic reprogramming induces the expansion of cord blood stem cells. J Clin Invest (2014) 1.09
B56 regulatory subunit of protein phosphatase 2A mediates valproic acid-induced p300 degradation. Mol Cell Biol (2005) 1.09
Expression levels of histone deacetylases determine the cell fate of hematopoietic progenitors. J Biol Chem (2009) 1.07
Methamphetamine downregulates striatal glutamate receptors via diverse epigenetic mechanisms. Biol Psychiatry (2013) 1.04
Mule determines the apoptotic response to HDAC inhibitors by targeted ubiquitination and destruction of HDAC2. Genes Dev (2011) 1.03
Valproate activates bovine leukemia virus gene expression, triggers apoptosis, and induces leukemia/lymphoma regression in vivo. Proc Natl Acad Sci U S A (2005) 1.02
Effects of valproic acid on the cell cycle and apoptosis through acetylation of histone and tubulin in a scirrhous gastric cancer cell line. J Exp Clin Cancer Res (2010) 1.01
Targeting mitochondrial STAT3 with the novel phospho-valproic acid (MDC-1112) inhibits pancreatic cancer growth in mice. PLoS One (2013) 1.01
Chemopreventive agent 3,3'-diindolylmethane selectively induces proteasomal degradation of class I histone deacetylases. Cancer Res (2010) 1.00
Acetylation of insulin receptor substrate-1 is permissive for tyrosine phosphorylation. BMC Biol (2004) 1.00
Deep brain stimulation, histone deacetylase inhibitors and glutamatergic drugs rescue resistance to fear extinction in a genetic mouse model. Neuropharmacology (2012) 0.98
Hydralazine target: from blood vessels to the epigenome. J Transl Med (2006) 0.98
Paternal RLIM/Rnf12 is a survival factor for milk-producing alveolar cells. Cell (2012) 0.97
HDAC inhibitors in experimental liver and kidney fibrosis. Fibrogenesis Tissue Repair (2013) 0.96
HDAC2 attenuates TRAIL-induced apoptosis of pancreatic cancer cells. Mol Cancer (2010) 0.96
Plant flavone apigenin inhibits HDAC and remodels chromatin to induce growth arrest and apoptosis in human prostate cancer cells: in vitro and in vivo study. Mol Carcinog (2011) 0.95
Spatially resolved optical and ultrastructural properties of colorectal and pancreatic field carcinogenesis observed by inverse spectroscopic optical coherence tomography. J Biomed Opt (2014) 0.95
HDAC inhibitors as cognitive enhancers in fear, anxiety and trauma therapy: where do we stand? Biochem Soc Trans (2014) 0.95
A combination of a ribonucleotide reductase inhibitor and histone deacetylase inhibitors downregulates EGFR and triggers BIM-dependent apoptosis in head and neck cancer. Oncotarget (2012) 0.94
Glucose depletion activates mmu-miR-466h-5p expression through oxidative stress and inhibition of histone deacetylation. Nucleic Acids Res (2012) 0.94
TSA downregulates Wilms tumor gene 1 (Wt1) expression at multiple levels. Nucleic Acids Res (2008) 0.93
Up-regulation of HLA class-I antigen expression and antigen-specific CTL response in cervical cancer cells by the demethylating agent hydralazine and the histone deacetylase inhibitor valproic acid. J Transl Med (2006) 0.91
Histone deacetylase inhibitors modulate the transcriptional regulation of guanylyl cyclase/natriuretic peptide receptor-a gene: interactive roles of modified histones, histone acetyltransferase, p300, AND Sp1. J Biol Chem (2014) 0.91
Histone deacetylase inhibitors reduce steroidogenesis through SCF-mediated ubiquitination and degradation of steroidogenic factor 1 (NR5A1). Mol Cell Biol (2007) 0.91
Epigenetics: a novel therapeutic approach for the treatment of Alzheimer's disease. Pharmacol Ther (2013) 0.90
Deacetylase inhibitors - focus on non-histone targets and effects. World J Biol Chem (2010) 0.90
SIAH ubiquitin ligases target the nonreceptor tyrosine kinase ACK1 for ubiquitinylation and proteasomal degradation. Oncogene (2012) 0.89
Phase I trial of ATRA-IV and Depakote in patients with advanced solid tumor malignancies. Cancer Biol Ther (2010) 0.88
The role of HDACs inhibitors in childhood and adolescence acute leukemias. J Biomed Biotechnol (2011) 0.88
Histone deacetylase classes I and II regulate Kaposi's sarcoma-associated herpesvirus reactivation. J Virol (2013) 0.87
Valproic acid: an anticonvulsant drug with potent antinociceptive and anti-inflammatory properties. Naunyn Schmiedebergs Arch Pharmacol (2013) 0.87
Valproic acid inhibits neural progenitor cell death by activation of NF-κB signaling pathway and up-regulation of Bcl-XL. J Biomed Sci (2011) 0.86
Epigenetic treatment of myelodysplastic syndromes and acute myeloid leukemias. Curr Med Chem (2008) 0.85
Potentiation of the anticancer effect of valproic acid, an antiepileptic agent with histone deacetylase inhibitory activity, by the kinase inhibitor Staurosporine or its clinically relevant analogue UCN-01. Br J Cancer (2006) 0.84
Functional activity of RLIM/Rnf12 is regulated by phosphorylation-dependent nucleocytoplasmic shuttling. Mol Biol Cell (2013) 0.84
Valproic acid affects membrane trafficking and cell-wall integrity in fission yeast. Genetics (2007) 0.84
Hippocampal HDAC4 contributes to postnatal fluoxetine-evoked depression-like behavior. Neuropsychopharmacology (2014) 0.83
What We Have Learned about Autism Spectrum Disorder from Valproic Acid. Patholog Res Int (2013) 0.83
Regulation of histone modifying enzymes by the ubiquitin-proteasome system. Biochim Biophys Acta (2014) 0.83
Genome-wide screening for genes associated with valproic acid sensitivity in fission yeast. PLoS One (2013) 0.83
Could valproic acid be an effective anticancer agent? The evidence so far. Expert Rev Anticancer Ther (2014) 0.82
The SIN3A/HDAC Corepressor Complex Functionally Cooperates with NANOG to Promote Pluripotency. Cell Rep (2017) 0.82
Histone deacetylase inhibition redistributes topoisomerase IIβ from heterochromatin to euchromatin. Nucleus (2011) 0.82
Loss of CFTR results in reduction of histone deacetylase 2 in airway epithelial cells. Am J Physiol Lung Cell Mol Physiol (2009) 0.81
Novel interaction between Apc5p and Rsp5p in an intracellular signaling pathway in Saccharomyces cerevisiae. Eukaryot Cell (2005) 0.81
USP4 inhibits p53 and NF-κB through deubiquitinating and stabilizing HDAC2. Oncogene (2015) 0.81
Histone deacetylase inhibition and dietary short-chain Fatty acids. ISRN Allergy (2011) 0.80
Caspase-3 and caspase-6 cleave STAT1 in leukemic cells. Oncotarget (2014) 0.80
STAT5 acetylation: Mechanisms and consequences for immunological control and leukemogenesis. JAKSTAT (2013) 0.80
Fractal Characterization of Chromatin Decompaction in Live Cells. Biophys J (2015) 0.80
Valproic acid causes proteasomal degradation of DICER and influences miRNA expression. PLoS One (2013) 0.80
Valproic acid inhibits proliferation of HER2-expressing breast cancer cells by inducing cell cycle arrest and apoptosis through Hsp70 acetylation. Int J Oncol (2015) 0.80
Small chemical chromatin effectors alter secondary metabolite production in Aspergillus clavatus. Toxins (Basel) (2013) 0.80
HDAC inhibitor valproic acid upregulates CAR in vitro and in vivo. Genet Vaccines Ther (2007) 0.79
A proapoptotic effect of valproic acid on progenitors of embryonic stem cell-derived glutamatergic neurons. Cell Death Dis (2013) 0.79
Regulation of LIM-domain-binding 1 protein expression by ubiquitination of Lys134. Biochem J (2010) 0.79
Valproic acid enhances the efficacy of radiation therapy by protecting normal hippocampal neurons and sensitizing malignant glioblastoma cells. Oncotarget (2015) 0.78
Loss of the deubiquitylase BAP1 alters class I histone deacetylase expression and sensitivity of mesothelioma cells to HDAC inhibitors. Oncotarget (2015) 0.78
Anti-Epileptic Drug Targets Ewing Sarcoma. J Pharm Sci Pharmacol (2014) 0.78
Chemopreventive effects of an HDAC2-selective inhibitor on rat colon carcinogenesis and APCmin/+ mouse intestinal tumorigenesis. J Pharmacol Exp Ther (2013) 0.77
Histone deacetylase inhibitor: antineoplastic agent and radiation modulator. Adv Exp Med Biol (2011) 0.77
Impact of trichostatin A and sodium valproate treatment on post-stroke neurogenesis and behavioral outcomes in immature mice. Front Cell Neurosci (2013) 0.77
Effects of histone deacetylase inhibitor valproic acid on skeletal myocyte development. Sci Rep (2014) 0.77
Histone Deacetylase Inhibitors as Anticancer Drugs. Int J Mol Sci (2017) 0.77
Activation of GATA4 gene expression at the early stage of cardiac specification. Front Chem (2014) 0.76
Potential of chromatin modifying compounds for the treatment of Alzheimer's disease. Pathobiol Aging Age Relat Dis (2012) 0.76
Long-term valproate treatment increases brain neuropeptide Y expression and decreases seizure expression in a genetic rat model of absence epilepsy. PLoS One (2013) 0.76
Translational regulation of NeuroD1 expression by FMRP: involvement in glutamatergic neuronal differentiation of cultured rat primary neural progenitor cells. Cell Mol Neurobiol (2013) 0.76
Fungi treated with small chemicals exhibit increased antimicrobial activity against facultative bacterial and yeast pathogens. Biomed Res Int (2014) 0.76
Brief Communication: Featured Article: Histone H2A mono-ubiquitination and cellular transformation are inversely related in N-nitrosodiethylamine-induced hepatocellular carcinoma. Exp Biol Med (Maywood) (2016) 0.75
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The polycomb group protein EZH2 is involved in progression of prostate cancer. Nature (2002) 18.30
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SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27. Nat Cell Biol (1999) 9.92
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Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase. Cell (1997) 8.99
Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation. Nature (2000) 8.59
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Class II histone deacetylases act as signal-responsive repressors of cardiac hypertrophy. Cell (2002) 7.10
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Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells. EMBO J (2001) 6.85
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Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression. EMBO J (2002) 5.33
Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia. Nature (1998) 5.30
Isolation and characterization of cDNAs corresponding to an additional member of the human histone deacetylase gene family. J Biol Chem (1997) 4.16
Isolation of a novel histone deacetylase reveals that class I and class II deacetylases promote SMRT-mediated repression. Genes Dev (2000) 4.00
ETO, fusion partner in t(8;21) acute myeloid leukemia, represses transcription by interaction with the human N-CoR/mSin3/HDAC1 complex. Proc Natl Acad Sci U S A (1998) 3.59
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Histone deacetylase inhibitors as new cancer drugs. Curr Opin Oncol (2001) 2.91
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The SUMO E3 ligase RanBP2 promotes modification of the HDAC4 deacetylase. EMBO J (2002) 2.56
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Histone deacetylase as a therapeutic target. Trends Endocrinol Metab (2001) 1.83
Ubiquitination-dependent cofactor exchange on LIM homeodomain transcription factors. Nature (2002) 1.80
RLIM inhibits functional activity of LIM homeodomain transcription factors via recruitment of the histone deacetylase complex. Nat Genet (1999) 1.56
Histone deacetylases as therapeutic targets in hematologic malignancies. Curr Opin Hematol (2002) 1.26
Multiple regions of ETO cooperate in transcriptional repression. J Biol Chem (2001) 1.18
Rapid induction of histone hyperacetylation and cellular differentiation in human breast tumor cell lines following degradation of histone deacetylase-1. J Biol Chem (2000) 1.04
Valproic acid for the treatment of pediatric malignant glioma. Klin Padiatr (1999) 1.01
The Stat5-RARalpha fusion protein represses transcription and differentiation through interaction with a corepressor complex. Blood (2002) 0.95
Therapeutic levels of sodium valproate inhibit mitotic indices in cells of neural origin. Brain Res (1985) 0.87
Antibody domain exchange is an immunological solution to carbohydrate cluster recognition. Science (2003) 6.68
Single-cell exome sequencing and monoclonal evolution of a JAK2-negative myeloproliferative neoplasm. Cell (2012) 5.16
Opposing LSD1 complexes function in developmental gene activation and repression programmes. Nature (2007) 4.12
miR-212 and miR-132 are required for epithelial stromal interactions necessary for mouse mammary gland development. Nat Genet (2010) 4.06
Acetylation of non-histone proteins modulates cellular signalling at multiple levels. Int J Biochem Cell Biol (2008) 3.56
Association between changes in air pollution levels during the Beijing Olympics and biomarkers of inflammation and thrombosis in healthy young adults. JAMA (2012) 3.52
Nature of nonfunctional envelope proteins on the surface of human immunodeficiency virus type 1. J Virol (2006) 3.34
Histone H2A monoubiquitination represses transcription by inhibiting RNA polymerase II transcriptional elongation. Mol Cell (2008) 3.18
Controlled vocabularies and semantics in systems biology. Mol Syst Biol (2011) 2.79
Ischaemic preconditioning-regulated miR-21 protects heart against ischaemia/reperfusion injury via anti-apoptosis through its target PDCD4. Cardiovasc Res (2010) 2.77
A randomized controlled trial of Licartin for preventing hepatoma recurrence after liver transplantation. Hepatology (2007) 2.66
Induction of HDAC2 expression upon loss of APC in colorectal tumorigenesis. Cancer Cell (2004) 2.66
An F876L mutation in androgen receptor confers genetic and phenotypic resistance to MDV3100 (enzalutamide). Cancer Discov (2013) 2.52
Cryo-EM study of the chromatin fiber reveals a double helix twisted by tetranucleosomal units. Science (2014) 2.37
Probing meiotic recombination and aneuploidy of single sperm cells by whole-genome sequencing. Science (2012) 2.14
Acetylation of Stat1 modulates NF-kappaB activity. Genes Dev (2006) 2.10
Oligomeric and conformational properties of a proteolytically mature, disulfide-stabilized human immunodeficiency virus type 1 gp140 envelope glycoprotein. J Virol (2002) 2.06
A phosphorylation-acetylation switch regulates STAT1 signaling. Genes Dev (2009) 1.98
Ubiquitination-dependent cofactor exchange on LIM homeodomain transcription factors. Nature (2002) 1.80
STAT3 induction of miR-146b forms a feedback loop to inhibit the NF-κB to IL-6 signaling axis and STAT3-driven cancer phenotypes. Sci Signal (2014) 1.79
The receptor of advanced glycation end products plays a central role in advanced oxidation protein products-induced podocyte apoptosis. Kidney Int (2012) 1.77
A comparative immunogenicity study of HIV-1 virus-like particles bearing various forms of envelope proteins, particles bearing no envelope and soluble monomeric gp120. Virology (2007) 1.74
IL-10 regulates murine lupus. J Immunol (2002) 1.70
Single-cell methylome landscapes of mouse embryonic stem cells and early embryos analyzed using reduced representation bisulfite sequencing. Genome Res (2013) 1.67
Maternal Rnf12/RLIM is required for imprinted X-chromosome inactivation in mice. Nature (2010) 1.64
SABIO-RK--database for biochemical reaction kinetics. Nucleic Acids Res (2011) 1.63
Reduced body size and decreased intestinal tumor rates in HDAC2-mutant mice. Cancer Res (2007) 1.54
Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases. Nature (2016) 1.52
Identification of a novel biomarker gene set with sensitivity and specificity for distinguishing between allograft rejection and tolerance. Liver Transpl (2012) 1.49
HAb18G/CD147 functions in invasion and metastasis of hepatocellular carcinoma. Mol Cancer Res (2007) 1.48
Computational fluid dynamics for investigation of saliva pressure in parotid obstruction. Laryngoscope (2012) 1.47
A nuclear isoform of the focal adhesion LIM-domain protein Trip6 integrates activating and repressing signals at AP-1- and NF-kappaB-regulated promoters. Genes Dev (2004) 1.46
Cardiorespiratory biomarker responses in healthy young adults to drastic air quality changes surrounding the 2008 Beijing Olympics. Res Rep Health Eff Inst (2013) 1.45
HAb18G (CD147), a cancer-associated biomarker and its role in cancer detection. Histopathology (2009) 1.45
Prognostic value of plasma heart-type fatty acid-binding protein in patients with acute pulmonary embolism: a meta-analysis. Chest (2014) 1.43
The coactivator of transcription CREB-binding protein interacts preferentially with the glycosylated form of Stat5. J Biol Chem (2003) 1.42
Inflammatory and oxidative stress responses of healthy young adults to changes in air quality during the Beijing Olympics. Am J Respir Crit Care Med (2012) 1.42
The association study of plasma levels of pigment epithelium-derived factor with acute coronary syndrome in the chinese han population. Cardiology (2013) 1.41
Remission of rheumatoid arthritis and potential determinants: a national multi-center cross-sectional survey. Clin Rheumatol (2014) 1.41
Anti-kelch-like 12 and anti-hexokinase 1: novel autoantibodies in primary biliary cirrhosis. Liver Int (2014) 1.40
Safety of infliximab therapy in rheumatoid arthritis patients with previous exposure to hepatitis B virus. Int J Rheum Dis (2013) 1.39
Overexpression and forced activation of stat5 in mammary gland of transgenic mice promotes cellular proliferation, enhances differentiation, and delays postlactational apoptosis. Mol Cancer Res (2002) 1.38
Clinical trial of valproic acid and all-trans retinoic acid in patients with poor-risk acute myeloid leukemia. Cancer (2005) 1.38
Crystal structure of HAb18G/CD147: implications for immunoglobulin superfamily homophilic adhesion. J Biol Chem (2008) 1.38
Structural and immunogenicity studies of a cleaved, stabilized envelope trimer derived from subtype A HIV-1. Vaccine (2009) 1.37
Interleukin-33 ameliorates experimental colitis through promoting Th2/Foxp3⁺ regulatory T-cell responses in mice. Mol Med (2012) 1.37
Whole-genome analysis of 5-hydroxymethylcytosine and 5-methylcytosine at base resolution in the human brain. Genome Biol (2014) 1.36
HDACi--targets beyond chromatin. Cancer Lett (2009) 1.32
The structural basis of gas-responsive transcription by the human nuclear hormone receptor REV-ERBbeta. PLoS Biol (2009) 1.31
The ubiquitin ligase Rnf6 regulates local LIM kinase 1 levels in axonal growth cones. Genes Dev (2005) 1.30
Path2Models: large-scale generation of computational models from biochemical pathway maps. BMC Syst Biol (2013) 1.29
Histone deacetylases: salesmen and customers in the post-translational modification market. Biol Cell (2009) 1.29
A genetic strategy to treat sickle cell anemia by coregulating globin transgene expression and RNA interference. Nat Biotechnol (2005) 1.28
The specific role of histone deacetylase 2 in adult neurogenesis. Neuron Glia Biol (2010) 1.27
Nuclear export is essential for the tumor-promoting activity of survivin. FASEB J (2006) 1.25
SBML2L(A)T(E)X: conversion of SBML files into human-readable reports. Bioinformatics (2009) 1.24
Tomographic subvolume alignment and subvolume classification applied to myosin V and SIV envelope spikes. J Struct Biol (2008) 1.24
Storing and annotating of kinetic data. In Silico Biol (2007) 1.24
Targeting radioimmunotherapy of hepatocellular carcinoma with iodine (131I) metuximab injection: clinical phase I/II trials. Int J Radiat Oncol Biol Phys (2006) 1.23
Mammary epithelial reconstitution with gene-modified stem cells assigns roles to Stat5 in luminal alveolar cell fate decisions, differentiation, involution, and mammary tumor formation. Stem Cells (2010) 1.23
Modification of nuclear PML protein by SUMO-1 regulates Fas-induced apoptosis in rheumatoid arthritis synovial fibroblasts. Proc Natl Acad Sci U S A (2007) 1.22
Cryo-EM structure of a transcribing cypovirus. Proc Natl Acad Sci U S A (2012) 1.20
Implementing the LIM code: the structural basis for cell type-specific assembly of LIM-homeodomain complexes. EMBO J (2008) 1.19
A genome-wide association study in Han Chinese identifies a susceptibility locus for primary Sjögren's syndrome at 7q11.23. Nat Genet (2013) 1.19
Focused dampening of antibody response to the immunodominant variable loops by engineered soluble gp140. AIDS Res Hum Retroviruses (2008) 1.19
Role of the frequency of blood CD4(+) CXCR5(+) CCR6(+) T cells in autoimmunity in patients with Sjögren's syndrome. Biochem Biophys Res Commun (2012) 1.18
MimoDB 2.0: a mimotope database and beyond. Nucleic Acids Res (2011) 1.18
Gigaxonin interacts with tubulin folding cofactor B and controls its degradation through the ubiquitin-proteasome pathway. Curr Biol (2005) 1.18
Involvement of CD147 in overexpression of MMP-2 and MMP-9 and enhancement of invasive potential of PMA-differentiated THP-1. BMC Cell Biol (2005) 1.17
Structure of the Leanyer orthobunyavirus nucleoprotein-RNA complex reveals unique architecture for RNA encapsidation. Proc Natl Acad Sci U S A (2013) 1.17
Atomic model of a cypovirus built from cryo-EM structure provides insight into the mechanism of mRNA capping. Proc Natl Acad Sci U S A (2011) 1.17
Proteasomal selection of multiprotein complexes recruited by LIM homeodomain transcription factors. Proc Natl Acad Sci U S A (2007) 1.16
H3.3 actively marks enhancers and primes gene transcription via opening higher-ordered chromatin. Genes Dev (2013) 1.14
Phosphorylation-acetylation switch in the regulation of STAT1 signaling. Mol Cell Endocrinol (2009) 1.13
Apoptosis on hepatoma cells but not on primary hepatocytes by histone deacetylase inhibitors valproate and ITF2357. J Hepatol (2005) 1.13
Epigenetic modifications in rheumatoid arthritis. Arthritis Res Ther (2008) 1.13
Regulation of estrogen-dependent transcription by the LIM cofactors CLIM and RLIM in breast cancer. Cancer Res (2009) 1.12
Electron microscopic and immunochemical analysis of the broadly neutralizing HIV-1-specific, anti-carbohydrate antibody, 2G12. Mol Immunol (2004) 1.11
The interaction of specific peptide aptamers with the DNA binding domain and the dimerization domain of the transcription factor Stat3 inhibits transactivation and induces apoptosis in tumor cells. Mol Cancer Res (2004) 1.11
Societal costs of rheumatoid arthritis in China: a hospital-based cross-sectional study. Arthritis Care Res (Hoboken) (2014) 1.11
Deregulation of Stat5 expression and activation causes mammary tumors in transgenic mice. Int J Cancer (2004) 1.10
Nuclear export of NF90 to stabilize IL-2 mRNA is mediated by AKT-dependent phosphorylation at Ser647 in response to CD28 costimulation. J Immunol (2008) 1.09
Function of HAb18G/CD147 in invasion of host cells by severe acute respiratory syndrome coronavirus. J Infect Dis (2005) 1.09
The biological functions of the versatile transcription factors STAT3 and STAT5 and new strategies for their targeted inhibition. J Mammary Gland Biol Neoplasia (2006) 1.09
The COPI vesicle complex binds and moves with survival motor neuron within axons. Hum Mol Genet (2011) 1.08
RU486-induced glucocorticoid receptor agonism is controlled by the receptor N terminus and by corepressor binding. J Biol Chem (2002) 1.07
Measurement of inflammation and oxidative stress following drastic changes in air pollution during the Beijing Olympics: a panel study approach. Ann N Y Acad Sci (2010) 1.07
Dynamic expression of LIM cofactors in the developing mouse neural tube. Dev Dyn (2006) 1.07
Enzyme kinetics informatics: from instrument to browser. FEBS J (2010) 1.06
Current strategies for the development of peptide-based anti-cancer therapeutics. J Pept Sci (2005) 1.06
Regression of cutaneous tumor lesions in patients intratumorally injected with a recombinant single-chain antibody-toxin targeted to ErbB2/HER2. Breast Cancer Res Treat (2003) 1.05
Sequence-specific peptide aptamers, interacting with the intracellular domain of the epidermal growth factor receptor, interfere with Stat3 activation and inhibit the growth of tumor cells. J Biol Chem (2003) 1.05
SUMOylation of the corepressor N-CoR modulates its capacity to repress transcription. Mol Biol Cell (2006) 1.04
Cardiomyocyte-specific overexpression of human stem cell factor improves cardiac function and survival after myocardial infarction in mice. Circulation (2009) 1.04