Published in Biochemistry on July 22, 2003
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Determining nuclear localization of alpha-synuclein in mouse brains. Neuroscience (2011) 0.80
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Altered machinery of protein synthesis is region- and stage-dependent and is associated with α-synuclein oligomers in Parkinson's disease. Acta Neuropathol Commun (2015) 0.77
Interaction between Neuromelanin and Alpha-Synuclein in Parkinson's Disease. Biomolecules (2015) 0.77
C-Terminal Tyrosine Residue Modifications Modulate the Protective Phosphorylation of Serine 129 of α-Synuclein in a Yeast Model of Parkinson's Disease. PLoS Genet (2016) 0.76
Age-related epigenetic regulation in the brain and its role in neuronal diseases. BMB Rep (2016) 0.75
Potential Role of Epigenetic Mechanism in Manganese Induced Neurotoxicity. Biomed Res Int (2016) 0.75
Sequestration of Ribosome during Protein Aggregate Formation: Contribution of ribosomal RNA. Sci Rep (2017) 0.75
Impaired c-Fos and polo-like kinase 2 induction in the limbic system of fear-conditioned α-synuclein transgenic mice. PLoS One (2012) 0.75
The impact of solubility and electrostatics on fibril formation by the H3 and H4 histones. Protein Sci (2011) 0.75
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α-Synuclein enhances histone H3 lysine-9 dimethylation and H3K9me2-dependent transcriptional responses. Sci Rep (2016) 0.75
From the baker to the bedside: yeast models of Parkinson's disease. Microb Cell (2015) 0.75
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DisProt: the Database of Disordered Proteins. Nucleic Acids Res (2006) 4.46
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Conformational constraints for amyloid fibrillation: the importance of being unfolded. Biochim Biophys Acta (2004) 3.69
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Intrinsic disorder is a common feature of hub proteins from four eukaryotic interactomes. PLoS Comput Biol (2006) 3.23
Disorder in the nuclear pore complex: the FG repeat regions of nucleoporins are natively unfolded. Proc Natl Acad Sci U S A (2003) 3.07
Intrinsic disorder in transcription factors. Biochemistry (2006) 3.06
Coupled folding and binding with alpha-helix-forming molecular recognition elements. Biochemistry (2005) 2.94
Environmental risk factors and Parkinson's disease: selective degeneration of nigral dopaminergic neurons caused by the herbicide paraquat. Neurobiol Dis (2002) 2.83
Exploring the folding landscape of a structured RNA. Proc Natl Acad Sci U S A (2001) 2.78
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Alternative splicing in concert with protein intrinsic disorder enables increased functional diversity in multicellular organisms. Proc Natl Acad Sci U S A (2006) 2.57
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Classification of intrinsically disordered regions and proteins. Chem Rev (2014) 2.48
Comparing and combining predictors of mostly disordered proteins. Biochemistry (2005) 2.45
Small-angle X-ray scattering from RNA, proteins, and protein complexes. Annu Rev Biophys Biomol Struct (2007) 2.36
Assessing protein disorder and induced folding. Proteins (2006) 2.33
Reduced vesicular storage of dopamine causes progressive nigrostriatal neurodegeneration. J Neurosci (2007) 2.28
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Predicting intrinsic disorder in proteins: an overview. Cell Res (2009) 2.24
Characterization of molecular recognition features, MoRFs, and their binding partners. J Proteome Res (2007) 2.23
Quantitative and comprehensive decomposition of the ion atmosphere around nucleic acids. J Am Chem Soc (2007) 2.20
Structural transitions and thermodynamics of a glycine-dependent riboswitch from Vibrio cholerae. J Mol Biol (2006) 2.19
A comparative study of motor-protein motions by using a simple elastic-network model. Proc Natl Acad Sci U S A (2003) 2.17
A bimodal distribution of two distinct categories of intrinsically disordered structures with separate functions in FG nucleoporins. Mol Cell Proteomics (2010) 2.09
Biophysical properties of the synucleins and their propensities to fibrillate: inhibition of alpha-synuclein assembly by beta- and gamma-synucleins. J Biol Chem (2002) 2.07
The flavonoid baicalein inhibits fibrillation of alpha-synuclein and disaggregates existing fibrils. J Biol Chem (2004) 2.02
Closing the folding chamber of the eukaryotic chaperonin requires the transition state of ATP hydrolysis. Cell (2003) 2.02
Toward a taxonomy of the denatured state: small angle scattering studies of unfolded proteins. Adv Protein Chem (2002) 2.02
The herbicide paraquat causes up-regulation and aggregation of alpha-synuclein in mice: paraquat and alpha-synuclein. J Biol Chem (2001) 1.99
The association of alpha-synuclein with membranes affects bilayer structure, stability, and fibril formation. J Biol Chem (2003) 1.97
Mining alpha-helix-forming molecular recognition features with cross species sequence alignments. Biochemistry (2007) 1.93
A general model for amyloid fibril assembly based on morphological studies using atomic force microscopy. Biophys J (2003) 1.93
Functional anthology of intrinsic disorder. 3. Ligands, post-translational modifications, and diseases associated with intrinsically disordered proteins. J Proteome Res (2007) 1.92
Rifampicin inhibits alpha-synuclein fibrillation and disaggregates fibrils. Chem Biol (2004) 1.91
Principles of RNA compaction: insights from the equilibrium folding pathway of the P4-P6 RNA domain in monovalent cations. J Mol Biol (2004) 1.90
Long single alpha-helical tail domains bridge the gap between structure and function of myosin VI. Nat Struct Mol Biol (2008) 1.88
Lysosomal degradation of alpha-synuclein in vivo. J Biol Chem (2010) 1.82
Alpha-synuclein overexpression protects against paraquat-induced neurodegeneration. J Neurosci (2003) 1.80
The fastest global events in RNA folding: electrostatic relaxation and tertiary collapse of the Tetrahymena ribozyme. J Mol Biol (2003) 1.80
Age-related irreversible progressive nigrostriatal dopaminergic neurotoxicity in the paraquat and maneb model of the Parkinson's disease phenotype. Eur J Neurosci (2003) 1.77
Malleable machines take shape in eukaryotic transcriptional regulation. Nat Chem Biol (2008) 1.76
D²P²: database of disordered protein predictions. Nucleic Acids Res (2012) 1.75
The oxidation state of DJ-1 regulates its chaperone activity toward alpha-synuclein. J Mol Biol (2005) 1.74
Heparin and other glycosaminoglycans stimulate the formation of amyloid fibrils from alpha-synuclein in vitro. Biochemistry (2002) 1.71
TOP-IDP-scale: a new amino acid scale measuring propensity for intrinsic disorder. Protein Pept Lett (2008) 1.70
Lipid-binding activity of intrinsically unstructured cytoplasmic domains of multichain immune recognition receptor signaling subunits. Biochemistry (2006) 1.68
Tau filaments from human brain and from in vitro assembly of recombinant protein show cross-beta structure. Proc Natl Acad Sci U S A (2003) 1.67
Introducing protein intrinsic disorder. Chem Rev (2014) 1.66
Accelerated alpha-synuclein fibrillation in crowded milieu. FEBS Lett (2002) 1.64
Lipid binding inhibits alpha-synuclein fibril formation. J Biol Chem (2003) 1.64
Composition Profiler: a tool for discovery and visualization of amino acid composition differences. BMC Bioinformatics (2007) 1.64
Do viral proteins possess unique biophysical features? Trends Biochem Sci (2008) 1.60
Network of dynamically important residues in the open/closed transition in polymerases is strongly conserved. Structure (2005) 1.60
Evaluation of ion binding to DNA duplexes using a size-modified Poisson-Boltzmann theory. Biophys J (2007) 1.60
Role of oxidative stress in paraquat-induced dopaminergic cell degeneration. J Neurochem (2005) 1.59
Rational drug design via intrinsically disordered protein. Trends Biotechnol (2006) 1.57
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Close encounters of the third kind: disordered domains and the interactions of proteins. Bioessays (2009) 1.56
Calmodulin signaling: analysis and prediction of a disorder-dependent molecular recognition. Proteins (2006) 1.51
Conformational behavior and aggregation of alpha-synuclein in organic solvents: modeling the effects of membranes. Biochemistry (2003) 1.51
Orderly order in protein intrinsic disorder distribution: disorder in 3500 proteomes from viruses and the three domains of life. J Biomol Struct Dyn (2012) 1.51
Behavioral and neurochemical effects of wild-type and mutated human alpha-synuclein in transgenic mice. Exp Neurol (2002) 1.51
Improving protein order-disorder classification using charge-hydropathy plots. BMC Bioinformatics (2014) 1.50
Dynamic charge interactions create surprising rigidity in the ER/K alpha-helical protein motif. Proc Natl Acad Sci U S A (2008) 1.50
Intrinsic disorder in scaffold proteins: getting more from less. Prog Biophys Mol Biol (2008) 1.49
Size and shape of detergent micelles determined by small-angle X-ray scattering. J Phys Chem B (2007) 1.49
MoRFpred, a computational tool for sequence-based prediction and characterization of short disorder-to-order transitioning binding regions in proteins. Bioinformatics (2012) 1.49
The effect of macromolecular crowding on protein aggregation and amyloid fibril formation. J Mol Recognit (2004) 1.48
Functional anthology of intrinsic disorder. 2. Cellular components, domains, technical terms, developmental processes, and coding sequence diversities correlated with long disordered regions. J Proteome Res (2007) 1.48
Probing counterion modulated repulsion and attraction between nucleic acid duplexes in solution. Proc Natl Acad Sci U S A (2005) 1.46
Unfoldomics of human genetic diseases: illustrative examples of ordered and intrinsically disordered members of the human diseasome. Protein Pept Lett (2009) 1.45
High stability of Discosoma DsRed as compared to Aequorea EGFP. Biochemistry (2003) 1.44
Surface-catalyzed amyloid fibril formation. J Biol Chem (2002) 1.43
Α-synuclein misfolding and Parkinson's disease. Biochim Biophys Acta (2011) 1.43
Microglial activation as a priming event leading to paraquat-induced dopaminergic cell degeneration. Neurobiol Dis (2006) 1.43