Published in Hum Hered on January 01, 2003
PTPN22 genetic variation: evidence for multiple variants associated with rheumatoid arthritis. Am J Hum Genet (2005) 3.95
Genome-wide association study implicates a chromosome 12 risk locus for late-onset Alzheimer disease. Am J Hum Genet (2009) 3.54
Physical activity and the association of common FTO gene variants with body mass index and obesity. Arch Intern Med (2008) 3.15
Haplotype-based association analysis via variance-components score test. Am J Hum Genet (2007) 2.93
Polymorphisms within the C-reactive protein (CRP) promoter region are associated with plasma CRP levels. Am J Hum Genet (2005) 2.71
Vitamin D-related genes, serum vitamin D concentrations and prostate cancer risk. Carcinogenesis (2009) 2.17
Genetic basis for adverse events after smallpox vaccination. J Infect Dis (2008) 2.09
Gene-environment interactions in schizophrenia: review of epidemiological findings and future directions. Schizophr Bull (2008) 2.09
Analysis of case-control studies of genetic and environmental factors with missing genetic information and haplotype-phase ambiguity. Genet Epidemiol (2005) 2.02
Protective effect of CRHR1 gene variants on the development of adult depression following childhood maltreatment: replication and extension. Arch Gen Psychiatry (2009) 2.01
Shrinkage Estimators for Robust and Efficient Inference in Haplotype-Based Case-Control Studies. J Am Stat Assoc (2009) 2.00
Methods to impute missing genotypes for population data. Hum Genet (2007) 1.98
Pooled analysis of genetic variation at chromosome 8q24 and colorectal neoplasia risk. Hum Mol Genet (2008) 1.96
Polymorphism in the CETP gene region, HDL cholesterol, and risk of future myocardial infarction: Genomewide analysis among 18 245 initially healthy women from the Women's Genome Health Study. Circ Cardiovasc Genet (2009) 1.92
Analysis of LOXL1 polymorphisms in a United States population with pseudoexfoliation glaucoma. Mol Vis (2008) 1.87
A common MECP2 haplotype associates with reduced cortical surface area in humans in two independent populations. Proc Natl Acad Sci U S A (2009) 1.84
A comprehensive literature review of haplotyping software and methods for use with unrelated individuals. Hum Genomics (2005) 1.84
A likelihood-based approach to mixed modeling with ambiguity in cluster identifiers. Biostatistics (2008) 1.72
Studying gene and gene-environment effects of uncommon and common variants on continuous traits: a marker-set approach using gene-trait similarity regression. Am J Hum Genet (2011) 1.71
Regression-based association analysis with clustered haplotypes through use of genotypes. Am J Hum Genet (2005) 1.71
Large-scale evaluation of candidate genes identifies associations between VEGF polymorphisms and bladder cancer risk. PLoS Genet (2007) 1.68
MYH9 and APOL1 are both associated with sickle cell disease nephropathy. Br J Haematol (2011) 1.67
Association of variants in two vitamin e transport genes with circulating vitamin e concentrations and prostate cancer risk. Cancer Res (2009) 1.65
Differential association of circadian genes with mood disorders: CRY1 and NPAS2 are associated with unipolar major depression and CLOCK and VIP with bipolar disorder. Neuropsychopharmacology (2010) 1.56
Association of common polymorphisms in IL10, and in other genes related to inflammatory response and obesity with colorectal cancer. Cancer Causes Control (2009) 1.52
Polymorphisms in DNA repair genes, smoking, and pancreatic adenocarcinoma risk. Cancer Res (2008) 1.49
Association of the DTNBP1 locus with schizophrenia in a U.S. population. Am J Hum Genet (2004) 1.45
Nucleotide excision repair pathway polymorphisms and pancreatic cancer risk: evidence for role of MMS19L. Cancer Epidemiol Biomarkers Prev (2009) 1.43
Von Hippel-Lindau (VHL) inactivation in sporadic clear cell renal cancer: associations with germline VHL polymorphisms and etiologic risk factors. PLoS Genet (2011) 1.43
Associations among race/ethnicity, ApoC-III genotypes, and lipids in HIV-1-infected individuals on antiretroviral therapy. PLoS Med (2006) 1.40
Association of genetic variation in genes implicated in the beta-catenin destruction complex with risk of breast cancer. Cancer Epidemiol Biomarkers Prev (2008) 1.39
The soluble epoxide hydrolase gene harbors sequence variation associated with susceptibility to and protection from incident ischemic stroke. Hum Mol Genet (2005) 1.34
Practical considerations for imputation of untyped markers in admixed populations. Genet Epidemiol (2010) 1.33
Influence of cytotoxic T lymphocyte-associated antigen 4 (CTLA4) common polymorphisms on outcome in treatment of melanoma patients with CTLA-4 blockade. J Immunother (2008) 1.31
Simple methods for assessing haplotype-environment interactions in case-only and case-control studies. Genet Epidemiol (2007) 1.29
Genetic variation in five genes important in telomere biology and risk for breast cancer. Br J Cancer (2007) 1.27
Retrospective analysis of haplotype-based case control studies under a flexible model for gene environment association. Biostatistics (2007) 1.26
Genetic approaches to functional gastrointestinal disorders. Gastroenterology (2010) 1.18
IL-6 gene variation is associated with IL-6 and C-reactive protein levels but not cardiovascular outcomes in the Cardiovascular Health Study. Hum Genet (2007) 1.18
Tumor necrosis factor and lymphotoxin-alpha polymorphisms and severe malaria in African populations. J Infect Dis (2009) 1.17
Vitamin D receptor gene polymorphisms and haplotypes and postmenopausal breast cancer risk. Breast Cancer Res (2008) 1.15
Phenotypic and genetic variation in leptin as determinants of weight regain. Int J Obes (Lond) (2010) 1.14
Population genetics of GYPB and association study between GYPB*S/s polymorphism and susceptibility to P. falciparum infection in the Brazilian Amazon. PLoS One (2011) 1.13
Mixed modeling and multiple imputation for unobservable genotype clusters. Stat Med (2008) 1.10
A general framework for studying genetic effects and gene-environment interactions with missing data. Biostatistics (2010) 1.10
Contributions of IBD5, IL23R, ATG16L1, and NOD2 to Crohn's disease risk in a population-based case-control study: evidence of gene-gene interactions. Inflamm Bowel Dis (2008) 1.09
Soluble CD14: genomewide association analysis and relationship to cardiovascular risk and mortality in older adults. Arterioscler Thromb Vasc Biol (2012) 1.08
A comprehensive approach to haplotype-specific analysis by penalized likelihood. Eur J Hum Genet (2010) 1.06
Pooled analysis of phosphatidylinositol 3-kinase pathway variants and risk of prostate cancer. Cancer Res (2010) 1.06
African glucose-6-phosphate dehydrogenase alleles associated with protection from severe malaria in heterozygous females in Tanzania. PLoS Genet (2015) 1.05
Soluble P-selectin, SELP polymorphisms, and atherosclerotic risk in European-American and African-African young adults: the Coronary Artery Risk Development in Young Adults (CARDIA) Study. Arterioscler Thromb Vasc Biol (2008) 1.05
Genetic polymorphisms in DNA repair and damage response genes and late normal tissue complications of radiotherapy for breast cancer. Br J Cancer (2009) 1.03
Association of genetic variation in mitotic kinases with breast cancer risk. Breast Cancer Res Treat (2009) 1.02
Hemifacial microsomia: from gestation to childhood. J Craniofac Surg (2009) 1.02
Transient receptor potential genes, smoking, occupational exposures and cough in adults. Respir Res (2012) 1.02
Statistics and bioinformatics in nutritional sciences: analysis of complex data in the era of systems biology. J Nutr Biochem (2010) 1.00
Genetic variants in PNPLA3 and risk of non-alcoholic fatty liver disease in a Han Chinese population. PLoS One (2012) 1.00
Genetic variation in sodium-dependent ascorbic acid transporters and risk of gastric cancer in Poland. Eur J Cancer (2009) 0.99
Uncoupling protein 2 gene polymorphisms are associated with obesity. Cardiovasc Diabetol (2012) 0.98
Markers of B-vitamin deficiency and frailty in older women. J Nutr Health Aging (2008) 0.98
Analysis of Case-Control Association Studies: SNPs, Imputation and Haplotypes. Stat Sci (2009) 0.96
Genetic variants in the KIF6 region and coronary event reduction from statin therapy. Hum Genet (2010) 0.95
Associations of lipoprotein lipase gene polymorphisms with longitudinal plasma lipid trends in young adults: The Coronary Artery Risk Development in Young Adults (CARDIA) study. Circ Cardiovasc Genet (2010) 0.93
Alcohol dehydrogenase genetic polymorphisms, low-to-moderate alcohol consumption, and risk of breast cancer. Alcohol Clin Exp Res (2007) 0.93
Cystic fibrosis transmembrane conductance regulator gene mutation and lung cancer risk. Lung Cancer (2010) 0.92
Multinomial logistic regression approach to haplotype association analysis in population-based case-control studies. BMC Genet (2006) 0.92
Re: the use of inferred haplotypes in downstream analysis. Am J Hum Genet (2007) 0.90
Glucose-6-phosphate dehydrogenase polymorphisms and susceptibility to mild malaria in Dogon and Fulani, Mali. Malar J (2014) 0.90
Common variants near melanocortin 4 receptor are associated with general and visceral adiposity in European- and African-American youth. J Pediatr (2010) 0.90
BCL11A enhancer haplotypes and fetal hemoglobin in sickle cell anemia. Blood Cells Mol Dis (2015) 0.90
Analysis of 30 genes (355 SNPS) related to energy homeostasis for association with adiposity in European-American and Yup'ik Eskimo populations. Hum Hered (2008) 0.89
A Bayesian hierarchical model for detecting haplotype-haplotype and haplotype-environment interactions in genetic association studies. Hum Hered (2011) 0.89
Contribution of higher risk genes and European admixture to Crohn's disease in African Americans. Inflamm Bowel Dis (2012) 0.88
Polymorphisms and haplotypes across the osteoprotegerin gene associated with bone mineral density and osteoporotic fractures. Osteoporos Int (2009) 0.88
An analysis of genetic variation across the MBL2 locus in Dutch Caucasians indicates that 3' haplotypes could modify circulating levels of mannose-binding lectin. Hum Genet (2005) 0.88
Genome-wide association analysis and fine mapping of NT-proBNP level provide novel insight into the role of the MTHFR-CLCN6-NPPA-NPPB gene cluster. Hum Mol Genet (2011) 0.88
SHP-2 and PI3-kinase genes PTPN11 and PIK3R1 may influence serum apoB and LDL cholesterol levels in normal women. Atherosclerosis (2007) 0.88
Common variation in KLKB1 and essential hypertension risk: tagging-SNP haplotype analysis in a case-control study. Hum Genet (2007) 0.87
Impact of interactions of cigarette smoking with NAT2 polymorphisms on rheumatoid arthritis risk in African Americans. Arthritis Rheum (2012) 0.87
Identification of ATPAF1 as a novel candidate gene for asthma in children. J Allergy Clin Immunol (2011) 0.86
Association of the angiotensinogen gene polymorphism with atherosclerosis and its risk traits in the Saudi population. BMC Cardiovasc Disord (2013) 0.86
Genome-wide association study reveals class I MHC-restricted T cell-associated molecule gene (CRTAM) variants interact with vitamin D levels to affect asthma exacerbations. J Allergy Clin Immunol (2011) 0.86
Carotid plaque and candidate genes related to inflammation and endothelial function in Hispanics from northern Manhattan. Stroke (2011) 0.86
Evaluation of the association between the AC3 genetic polymorphisms and obesity in a Chinese Han population. PLoS One (2010) 0.85
Polymorphisms in estrogen- and androgen-metabolizing genes and the risk of gastric cancer. Carcinogenesis (2008) 0.85
Chemokine polymorphisms and lymphoma: a pooled analysis. Leuk Lymphoma (2010) 0.84
Association tests based on the principal-component analysis. BMC Proc (2007) 0.84
Haplotype reconstruction error as a classical misclassification problem: introducing sensitivity and specificity as error measures. PLoS One (2008) 0.84
Inter-population variability of DEFA3 gene absence: correlation with haplotype structure and population variability. BMC Genomics (2007) 0.84
Pathway-guided identification of gene-gene interactions. Ann Hum Genet (2014) 0.83
Evaluating haplotype effects in case-control studies via penalized-likelihood approaches: prospective or retrospective analysis? Genet Epidemiol (2010) 0.83
Contribution of alpha- and beta-defensins to lung function decline and infection in smokers: an association study. Respir Res (2006) 0.83
Clinical and genetic predictors of weight gain in patients diagnosed with breast cancer. Br J Cancer (2013) 0.83
Genetic variation in C-reactive protein (CRP) gene may be associated with risk of systemic lupus erythematosus and CRP concentrations. J Rheumatol (2008) 0.83
Emilin1 gene and essential hypertension: a two-stage association study in northern Han Chinese population. BMC Med Genet (2009) 0.82
Modeling haplotype-haplotype interactions in case-control genetic association studies. Front Genet (2012) 0.82
Association mapping by generalized linear regression with density-based haplotype clustering. Genet Epidemiol (2009) 0.82
Phosphatidylinositol 3-kinase p85alpha regulatory subunit gene PIK3R1 haplotype is associated with body fat and serum leptin in a female twin population. Diabetologia (2006) 0.82
Integrated analysis of genetic data with R. Hum Genomics (2006) 0.82
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Microsatellite instability and 8p allelic imbalance in stage B2 and C colorectal cancers. J Natl Cancer Inst (1999) 3.46
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