Published in Proc Natl Acad Sci U S A on December 01, 1985
The scanning model for translation: an update. J Cell Biol (1989) 31.23
An analysis of vertebrate mRNA sequences: intimations of translational control. J Cell Biol (1991) 12.00
Context effects and inefficient initiation at non-AUG codons in eucaryotic cell-free translation systems. Mol Cell Biol (1989) 5.16
Errors and alternatives in reading the universal genetic code. Microbiol Rev (1989) 4.67
Adeno-associated virus general transduction vectors: analysis of proviral structures. J Virol (1988) 4.64
Nucleotide sequence and genome organization of human parvovirus B19 isolated from the serum of a child during aplastic crisis. J Virol (1986) 4.33
Downstream secondary structure facilitates recognition of initiator codons by eukaryotic ribosomes. Proc Natl Acad Sci U S A (1990) 3.95
Positive and negative autoregulation of the adeno-associated virus type 2 genome. J Virol (1986) 3.67
High molecular mass forms of basic fibroblast growth factor are initiated by alternative CUG codons. Proc Natl Acad Sci U S A (1989) 3.45
Parvovirus replication. Microbiol Rev (1990) 3.37
Ribosomal initiation from an ACG codon in the Sendai virus P/C mRNA. EMBO J (1988) 3.33
Identification of the trans-acting Rep proteins of adeno-associated virus by antibodies to a synthetic oligopeptide. J Virol (1986) 3.09
Identification of amino acid residues in the capsid proteins of adeno-associated virus type 2 that contribute to heparan sulfate proteoglycan binding. J Virol (2003) 2.93
Genetic selection for mutations that reduce or abolish ribosomal recognition of the HIS4 translational initiator region. Mol Cell Biol (1988) 2.80
Novel transcription map for the B19 (human) pathogenic parvovirus. J Virol (1987) 2.74
Complete nucleotide sequence and genome organization of bovine parvovirus. J Virol (1986) 2.69
The pim-1 oncogene encodes two related protein-serine/threonine kinases by alternative initiation at AUG and CUG. EMBO J (1991) 2.26
A complex translational program generates multiple novel proteins from the latently expressed kaposin (K12) locus of Kaposi's sarcoma-associated herpesvirus. J Virol (1999) 2.16
Characterization of cloned chicken anemia virus DNA that contains all elements for the infectious replication cycle. J Virol (1991) 2.12
The serum-inducible mouse gene Krox-24 encodes a sequence-specific transcriptional activator. Mol Cell Biol (1990) 2.04
Alternate mRNA splicing is required for synthesis of adeno-associated virus VP1 capsid protein. J Virol (1988) 2.03
The immediate downstream codon strongly influences the efficiency of utilization of eukaryotic translation initiation codons. EMBO J (1994) 1.93
Positions +5 and +6 can be major determinants of the efficiency of non-AUG initiation codons for protein synthesis. EMBO J (1994) 1.90
Efficient initiation of mammalian mRNA translation at a CUG codon. Nucleic Acids Res (1989) 1.90
Synthesis of adeno-associated virus structural proteins requires both alternative mRNA splicing and alternative initiations from a single transcript. J Virol (1988) 1.89
The adeno-associated virus (AAV) Rep protein acts as both a repressor and an activator to regulate AAV transcription during a productive infection. J Virol (1997) 1.89
Regulation of adeno-associated virus gene expression in 293 cells: control of mRNA abundance and translation. J Virol (1988) 1.80
Adeno-associated virus type 2 VP2 capsid protein is nonessential and can tolerate large peptide insertions at its N terminus. J Virol (2004) 1.67
The minor capsid protein VP1 of the autonomous parvovirus minute virus of mice is dispensable for encapsidation of progeny single-stranded DNA but is required for infectivity. J Virol (1993) 1.67
Equine infectious anemia virus tat: insights into the structure, function, and evolution of lentivirus trans-activator proteins. J Virol (1990) 1.61
Detailed transcription map of Aleutian mink disease parvovirus. J Virol (1988) 1.58
Cloning and characterization of cDNAs encoding equine infectious anemia virus tat and putative Rev proteins. J Virol (1990) 1.56
Scanning independent ribosomal initiation of the Sendai virus Y proteins in vitro and in vivo. EMBO J (1989) 1.54
Adeno-associated virus rep protein synthesis during productive infection. J Virol (1989) 1.54
Assembly of viruslike particles by recombinant structural proteins of adeno-associated virus type 2 in insect cells. J Virol (1992) 1.52
Expression strategy of a phlebovirus: biogenesis of proteins from the Rift Valley fever virus M segment. J Virol (1990) 1.50
Efficiency of translation initiation by non-AUG codons in Saccharomyces cerevisiae. Mol Cell Biol (1988) 1.50
Non-AUG initiation of AGAMOUS mRNA translation in Arabidopsis thaliana. Mol Cell Biol (1999) 1.47
Identification of alternatively spliced mRNAs encoding potential new regulatory proteins in cattle infected with bovine leukemia virus. J Virol (1993) 1.42
The adeno-associated virus rep gene inhibits replication of an adeno-associated virus/simian virus 40 hybrid genome in cos-7 cells. J Virol (1988) 1.42
The cellular transcription factor SP1 and an unknown cellular protein are required to mediate Rep protein activation of the adeno-associated virus p19 promoter. J Virol (1997) 1.34
The adeno-associated virus type 2 p40 promoter requires a proximal Sp1 interaction and a p19 CArG-like element to facilitate Rep transactivation. J Virol (1997) 1.34
uORFs with unusual translational start codons autoregulate expression of eukaryotic ornithine decarboxylase homologs. Proc Natl Acad Sci U S A (2008) 1.33
Translation of equine infectious anemia virus bicistronic tat-rev mRNA requires leaky ribosome scanning of the tat CTG initiation codon. J Virol (1993) 1.26
The parainfluenza virus type 1 P/C gene uses a very efficient GUG codon to start its C' protein. J Virol (1992) 1.25
Producing recombinant adeno-associated virus in foster cells: overcoming production limitations using a baculovirus-insect cell expression strategy. Hum Gene Ther (2009) 1.24
Site-directed mutagenesis of adeno-associated virus type 2 structural protein initiation codons: effects on regulation of synthesis and biological activity. J Virol (1994) 1.19
Evidence for the frequent use of TTG as the translation initiation codon of mitochondrial protein genes in the nematodes, Ascaris suum and Caenorhabditis elegans. Nucleic Acids Res (1990) 1.12
Influence of the Theiler's virus L* protein on macrophage infection, viral persistence, and neurovirulence. J Virol (2000) 1.10
More surprises in translation: initiation without the initiator tRNA. Proc Natl Acad Sci U S A (2000) 1.06
Bioengineering of AAV2 capsid at specific serine, threonine, or lysine residues improves its transduction efficiency in vitro and in vivo. Hum Gene Ther Methods (2013) 1.06
Alternative 5' exons either provide or deny an initiator methionine codon to the same alpha-tubulin coding region. Nucleic Acids Res (1987) 1.05
The abundant R2 mRNA generated by aleutian mink disease parvovirus is tricistronic, encoding NS2, VP1, and VP2. J Virol (2007) 0.97
A GC-box motif upstream of the B19 parvovirus unique promoter is important for in vitro transcription. J Virol (1989) 0.97
Initiation of translation at an AUA codon for an archaebacterial protein gene expressed in E.coli. Nucleic Acids Res (1991) 0.93
An initiation codon mutation (AUG----GUG) of the human alpha 1-globin gene. Structural characterization and evidence for a mild thalassemic phenotype. J Clin Invest (1987) 0.88
Non-AUG translation initiation in a plant RNA virus: a forty-amino-acid extension is added to the N terminus of the soil-borne wheat mosaic virus capsid protein. J Virol (1998) 0.85
Stimulation of Sendai virus C' protein synthesis by cycloheximide. Biochem J (1997) 0.85
Translation initiation by non-AUG codons in Arabidopsis thaliana transgenic plants. Plant Cell Rep (2005) 0.80
Structure and variation of the mitochondrial genome of fishes. BMC Genomics (2016) 0.79
Viral and Cellular Components of AAV2 Replication Compartments. Open Virol J (2013) 0.77
AAV: An Overview of Unanswered Questions. Hum Gene Ther (2017) 0.77
Structural Studies of AAV2 Rep68 Reveal a Partially Structured Linker and Compact Domain Conformation. Biochemistry (2015) 0.76
Sequencing end-labeled DNA with base-specific chemical cleavages. Methods Enzymol (1980) 287.68
A catalogue of splice junction sequences. Nucleic Acids Res (1982) 39.41
Preparative and analytical purification of DNA from agarose. Proc Natl Acad Sci U S A (1979) 27.20
Comparison of initiation of protein synthesis in procaryotes, eucaryotes, and organelles. Microbiol Rev (1983) 24.58
Nucleotide sequence and organization of the adeno-associated virus 2 genome. J Virol (1983) 7.52
Definition of a novel promoter for the major adenovirus-associated virus mRNA. Cell (1980) 7.42
Evidence for a single-stranded adenovirus-associated virus genome: formation of a DNA density hybrid on release of viral DNA. Proc Natl Acad Sci U S A (1969) 5.78
Initiation of haemoglobin synthesis by methionyl-tRNA. Nature (1970) 3.99
Herpes simplex virus types 1 and 2 completely help adenovirus-associated virus replication. J Virol (1981) 3.72
Initiation of hemoglobin synthesis. Specific inhibition by antibiotics and bacteriophage ribonucleic acid. Biochemistry (1971) 3.50
Structural proteins of adenovirus-associated viruses. J Virol (1971) 3.03
Spliced adenovirus-associated virus RNA. Proc Natl Acad Sci U S A (1979) 2.99
Columns for rapid chromatographic separation of small amounts of tracer-labeled transfer ribonucleic acids. Anal Biochem (1971) 2.76
Transcripts of the adeno-associated virus genome: mapping of the major RNAs. J Virol (1980) 2.42
Characterization of adenovirus-associated virus-induced polypeptides in KB cells. J Virol (1978) 2.40
Prevention of NH2-terminal acetylation of proteins synthesized in cell-free systems. J Biol Chem (1977) 2.38
Studies on polynucleotides. LXVII. Initiation of protein synthesis in vitro as studied by using ribopolynucleotides with repeating nucleotide sequences as messengers. J Mol Biol (1967) 2.02
Locations of adenovirus genes required for the replication of adenovirus-associated virus. Proc Natl Acad Sci U S A (1981) 1.90
Adeno-associated virus proteins: origin of the capsid components. J Virol (1984) 1.84
Initiation codon mutation as a cause of alpha thalassemia. J Biol Chem (1984) 1.45
Structural proteins of adenovirus-associated virus: subspecies and their relatedness. J Virol (1983) 1.34
Translation of synthetic messenger RNA. Cold Spring Harb Symp Quant Biol (1966) 1.33
Polypeptide structure and encoding location of the adenovirus serotype 2 late, nonstructural 33K protein. J Virol (1983) 1.28
Primary structure, gene organization and polypeptide expression of poliovirus RNA. Nature (1981) 16.61
Processing of adenovirus 2-induced proteins. J Virol (1973) 12.52
Enhanced phosphorylation of p53 by ATM in response to DNA damage. Science (1998) 10.89
DNA damage activates p53 through a phosphorylation-acetylation cascade. Genes Dev (1998) 7.78
Measurement of serum DNA-binding activity in systemic lupus erythematosus. N Engl J Med (1969) 6.16
Evidence for a single-stranded adenovirus-associated virus genome: formation of a DNA density hybrid on release of viral DNA. Proc Natl Acad Sci U S A (1969) 5.78
A second virus-encoded proteinase involved in proteolytic processing of poliovirus polyprotein. Cell (1986) 5.53
Proteolytic processing of poliovirus polypeptides: antibodies to polypeptide P3-7c inhibit cleavage at glutamine-glycine pairs. Proc Natl Acad Sci U S A (1982) 5.50
A non-AUG translational initiation in c-myc exon 1 generates an N-terminally distinct protein whose synthesis is disrupted in Burkitt's lymphomas. Cell (1988) 5.49
Post-translational modifications and activation of p53 by genotoxic stresses. Eur J Biochem (2001) 5.43
Evidence for a single-stranded adenovirus-associated virus genome: isolation and separation of complementary single strands. J Virol (1970) 4.73
DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product. Cell (1995) 4.64
Concatemers of alternating plus and minus strands are intermediates in adenovirus-associated virus DNA synthesis. Proc Natl Acad Sci U S A (1976) 4.62
Complete nucleotide sequence of wild-type hepatitis A virus: comparison with different strains of hepatitis A virus and other picornaviruses. J Virol (1987) 4.49
Distinctive nucleotide sequences adjacent to multiple initiation and termination sites of an early vaccinia virus gene. Cell (1981) 4.42
Mapping of late adenovirus genes by cell-free translation of RNA selected by hybridization to specific DNA fragments. Proc Natl Acad Sci U S A (1975) 4.35
A unique form of terminal redundancy in adenovirus DNA molecules. Proc Natl Acad Sci U S A (1972) 4.18
Identification of the SV40 agnogene product: a DNA binding protein. Nature (1981) 3.80
Herpes simplex virus types 1 and 2 completely help adenovirus-associated virus replication. J Virol (1981) 3.72
Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53. Mol Cell Biol (1992) 3.68
Identification of the initiation site of poliovirus polyprotein synthesis. J Virol (1982) 3.62
Membrane-dependent uridylylation of the genome-linked protein VPg of poliovirus. Proc Natl Acad Sci U S A (1983) 3.58
Location and identification of the genes for adenovirus type 2 early polypeptides. Cell (1976) 3.58
Nucleic acid from an adeno-associated virus: chemical and physical studies. Proc Natl Acad Sci U S A (1966) 3.55
Cell-free synthesis of adenovirus 2 proteins programmed by fractionated messenger RNA: a comparison of polypeptide products and messenger RNA lengths. Proc Natl Acad Sci U S A (1974) 3.52
A human RNA polymerase II complex associated with SRB and DNA-repair proteins. Nature (1996) 3.50
Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation. EMBO J (1999) 3.46
Adenovirus early region 1B 58,000-dalton tumor antigen is physically associated with an early region 4 25,000-dalton protein in productively infected cells. J Virol (1984) 3.38
Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53, and the human Ku autoantigen. Mol Cell Biol (1990) 3.30
Membrane fractions active in poliovirus RNA replication contain VPg precursor polypeptides. Virology (1983) 3.28
The retinoblastoma protein is phosphorylated on multiple sites by human cdc2. EMBO J (1991) 3.15
A membrane-associated precursor to poliovirus VPg identified by immunoprecipitation with antibodies directed against a synthetic heptapeptide. Cell (1982) 3.07
RNA production in adenovirus-infected KB cells. Virology (1965) 3.06
Structural proteins of adenovirus-associated viruses. J Virol (1971) 3.03
Self-complementarity of terminal sequences within plus or minus strands of adenovirus-associated virus DNA. Proc Natl Acad Sci U S A (1973) 2.96
Molecular cloning and characterization of hepatitis A virus cDNA. Proc Natl Acad Sci U S A (1983) 2.92
Poliovirus replication proteins: RNA sequence encoding P3-1b and the sites of proteolytic processing. Proc Natl Acad Sci U S A (1981) 2.91
Nucleic acid homology studies of adenovirus type 7-SV40 interactions. Proc Natl Acad Sci U S A (1966) 2.86
Further mapping of late adenovirus genes by cell-free translation of RNA selected by hybridization to specific DNA fragments. Cell (1977) 2.78
Incompletely base-paired flip-flop terminal loops link the two DNA strands of the vaccinia virus genome into one uninterrupted polynucleotide chain. Cell (1982) 2.76
Adenovirus-associated virus multiplication. VII. Helper requirement for viral deoxyribonucleic acid and ribonucleic acid synthesis. J Virol (1972) 2.74
Purification and characterization of a DNA-dependent RNA polymerase from vaccinia virions. J Biol Chem (1980) 2.66
Simian virus 40 integration site in an adenovirus 7-simian virus 40 hybrid DNA molecule. Proc Natl Acad Sci U S A (1971) 2.64
Identification of a gene encoding a yeast histone H4 acetyltransferase. J Biol Chem (1995) 2.62
DNA binding provides a signal for phosphorylation of the RNA polymerase II heptapeptide repeats. Genes Dev (1992) 2.56
SCH-C (SCH 351125), an orally bioavailable, small molecule antagonist of the chemokine receptor CCR5, is a potent inhibitor of HIV-1 infection in vitro and in vivo. Proc Natl Acad Sci U S A (2001) 2.49
Preparation of a cell-free protein-synthesizing system from wheat germ. Methods Enzymol (1983) 2.43
Normal tRNAs promote ribosomal frameshifting. Cell (1979) 2.41
Characterization of adenovirus-associated virus-induced polypeptides in KB cells. J Virol (1978) 2.40
p53 transcriptional activity is essential for p53-dependent apoptosis following DNA damage. EMBO J (2000) 2.38
Characterization of soluble hepatitis C virus RNA-dependent RNA polymerase expressed in Escherichia coli. J Virol (1999) 2.37
Identification and characterization of an immunologically conserved adenovirus early region 11,000 Mr protein and its association with the nuclear matrix. J Mol Biol (1982) 2.36
Pattern of protein synthesis in monkey cells infected by simian virus 40. J Virol (1972) 2.35
Protein processing map of poliovirus. J Virol (1984) 2.33
Expression of a cloned gene segment of poliovirus in E. coli: evidence for autocatalytic production of the viral proteinase. Cell (1984) 2.29
The amino acid sequence of murine p53 determined from a c-DNA clone. Virology (1984) 2.15
Block to multiplication of adenovirus serotype 2 in monkey cells. J Virol (1975) 2.10
Damage-mediated phosphorylation of human p53 threonine 18 through a cascade mediated by a casein 1-like kinase. Effect on Mdm2 binding. J Biol Chem (2000) 2.08
Human HSP27 is phosphorylated at serines 78 and 82 by heat shock and mitogen-activated kinases that recognize the same amino acid motif as S6 kinase II. J Biol Chem (1992) 2.08
Adenovirus-associated virus multiplication. VI. Base compostion of the deoxyribonucleic acid strand species and strand-specific in vivo transcription. J Virol (1971) 2.05
Cleavage sites in the polypeptide precursors of poliovirus protein P2-X. Virology (1981) 2.04
Adenovirus type 2 early proteins: assignment of the early region 1A proteins synthesized in vivo and in vitro to specific mRNAs. Virology (1981) 2.04
Genetic relatedness among mycoplasmas as determined by nucleic acid homology. J Bacteriol (1966) 2.00
Cleavage sites within the poliovirus capsid protein precursors. J Virol (1982) 1.95
Enhanced differential synthesis of proteins in a mammalian cell-free system by addition of polyamines. J Biol Chem (1975) 1.93
Interaction of coxsackievirus B3 with the full length coxsackievirus-adenovirus receptor. Nat Struct Biol (2001) 1.91
Locations of adenovirus genes required for the replication of adenovirus-associated virus. Proc Natl Acad Sci U S A (1981) 1.90
Synthesis of adeno-associated virus structural proteins requires both alternative mRNA splicing and alternative initiations from a single transcript. J Virol (1988) 1.89
Adenovirus-associated virus multiplication. IX. Extent of transcription of the viral genome in vivo. J Virol (1972) 1.87
Treating acute stroke patients with intravenous tPA. The OSF stroke network experience. Stroke (2000) 1.87
Viral DNA and a viral peptide can act as cofactors of adenovirus virion proteinase activity. Nature (1993) 1.86
Propagation and purification of high-titer human cytomegalovirus. Appl Microbiol (1971) 1.85
Adeno-associated virus proteins: origin of the capsid components. J Virol (1984) 1.84
Sites of UV-induced phosphorylation of the p34 subunit of replication protein A from HeLa cells. J Biol Chem (1997) 1.84
A p53-independent pathway for activation of WAF1/CIP1 expression following oxidative stress. J Biol Chem (1995) 1.82
Separate helper functions provided by adenovirus for adenovirus-associated virus multiplication. Nat New Biol (1973) 1.82
Phosphorylation of murine p53 at ser-18 regulates the p53 responses to DNA damage. Proc Natl Acad Sci U S A (2000) 1.80
The DNA-activated protein kinase is required for the phosphorylation of replication protein A during simian virus 40 DNA replication. Proc Natl Acad Sci U S A (1994) 1.79
Genetic analysis of human immunodeficiency virus type 1 envelope V3 region isolates from mothers and infants after perinatal transmission. J Virol (1995) 1.77
Genetic relatedness studies with adenovirus-associated viruses. J Virol (1968) 1.76
Conditional lethal mutants of adenovirus type 2-simian virus 40 hybrids. II. Ad2+ND1 host-range mutants that synthesize fragments of the Ad2+ND1 30K protein. J Virol (1976) 1.76
Mapping of phosphomonoester and apparent phosphodiester bonds of the oncogene product p53 from simian virus 40-transformed 3T3 cells. Proc Natl Acad Sci U S A (1986) 1.72
Mapping of base sequence heterologies between genomes from different adenovirus serotypes. Virology (1973) 1.71
Signaling to p53: breaking the posttranslational modification code. Pathol Biol (Paris) (2000) 1.67
Phosphorylation of serine 392 stabilizes the tetramer formation of tumor suppressor protein p53. Biochemistry (1997) 1.66
Adenovirus-associated virus multiplication. 8. Analysis of in vivo transcription induced by complete or partial helper viruses. J Virol (1972) 1.65
Double-stranded DNA induces the phosphorylation of several proteins including the 90 000 mol. wt. heat-shock protein in animal cell extracts. EMBO J (1985) 1.64
Mutation of the serine 15 phosphorylation site of human p53 reduces the ability of p53 to inhibit cell cycle progression. Oncogene (1993) 1.63
The human double-stranded DNA-activated protein kinase phosphorylates the 90-kDa heat-shock protein, hsp90 alpha at two NH2-terminal threonine residues. J Biol Chem (1989) 1.60
Transcription in vivo of a defective parvovirus: sedimentation and electrophoretic analysis of RNA synthesized by adenovirus-associated virus and its helper adenovirus. Virology (1974) 1.57
Binding of mammalian ribosomes to MS2 phage RNA reveals an overlapping gene encoding a lysis function. Cell (1979) 1.56
Two human 90-kDa heat shock proteins are phosphorylated in vivo at conserved serines that are phosphorylated in vitro by casein kinase II. J Biol Chem (1989) 1.56
DNA-dependent protein kinase is activated by nicks and larger single-stranded gaps. J Biol Chem (1994) 1.56
DNA-minus temperature-sensitive mutants of adenovirus type 5 help adenovirus-associated virus replication. J Virol (1975) 1.54
Early region 1B of adenovirus 2 encodes two coterminal proteins of 495 and 155 amino acid residues. J Virol (1984) 1.51
Poliovirus RNA synthesis in vitro: structural elements and antibody inhibition. Virology (1983) 1.51
Interaction of human adenovirus serotype 2 with human lymphoid cells. Virology (1988) 1.49
Hepatitis C virus internal ribosome entry site (IRES) stem loop IIId contains a phylogenetically conserved GGG triplet essential for translation and IRES folding. J Virol (2000) 1.47
The origin and destiny of adenovirus proteins. Cold Spring Harb Symp Quant Biol (1975) 1.46
Adenovirus coded deoxyribonucleic acid binding protein. Isolation, physical properties, and effects of proteolytic digestion. Biochemistry (1980) 1.46