Published in Genetics on April 01, 1964
Statistical method for testing the neutral mutation hypothesis by DNA polymorphism. Genetics (1989) 73.50
A molecular approach to the study of genic heterozygosity in natural populations. II. Amount of variation and degree of heterozygosity in natural populations of Drosophila pseudoobscura. Genetics (1966) 30.66
Description and power analysis of two tests for detecting recent population bottlenecks from allele frequency data. Genetics (1996) 12.75
THE INTERACTION OF SELECTION AND LINKAGE. II. OPTIMUM MODELS. Genetics (1964) 10.77
The stability of linked systems of loci with a small population size. Genetics (1968) 10.19
Expected linkage disequilibrium for a neutral locus linked to a chromosomal arrangement. Genetics (1983) 8.38
VNTR allele frequency distributions under the stepwise mutation model: a computer simulation approach. Genetics (1993) 8.22
Polymorphisms in continental and island populations of Drosophila willistoni. Proc Natl Acad Sci U S A (1971) 6.28
The genetic structure of natural populations of Drosophila melanogaster. XII. Linkage disequilibrium in a large local population. Genetics (1974) 5.72
Allelic genealogy under overdominant and frequency-dependent selection and polymorphism of major histocompatibility complex loci. Genetics (1990) 5.11
Genetic heterogeneity within electrophoretic "alleles" of xanthine dehydrogenase in Drosophila pseudoobscura. Genetics (1976) 4.92
An approach to population and evolutionary genetic theory for genes in mitochondria and chloroplasts, and some results. Genetics (1983) 4.85
New methods employing multilocus genotypes to select or exclude populations as origins of individuals. Genetics (1999) 4.72
The genetic structure of natural populations of Drosophila melanogaster. V. Coupling-repulsion effect of spontaneous mutant polygenes controlling viability. Genetics (1968) 4.65
Genetic distances and reconstruction of phylogenetic trees from microsatellite DNA. Genetics (1996) 4.55
The age of a neutral mutant persisting in a finite population. Genetics (1973) 4.44
Genetic variability and effective population size when local extinction and recolonization of subpopulations are frequent. Proc Natl Acad Sci U S A (1980) 4.37
Phenomics: the next challenge. Nat Rev Genet (2010) 4.20
Random drift and culture change. Proc Biol Sci (2004) 4.11
Genetic variation in natural populations of five Drosophila species and the hypothesis of the selective neutrality of protein polymorphisms. Genetics (1974) 3.97
Organelle gene diversity under migration, mutation, and drift: equilibrium expectations, approach to equilibrium, effects of heteroplasmic cells, and comparison to nuclear genes. Genetics (1989) 3.96
A simple genealogical structure of strongly balanced allelic lines and trans-species evolution of polymorphism. Proc Natl Acad Sci U S A (1990) 3.85
Novel multilocus measure of linkage disequilibrium to estimate past effective population size. Genome Res (2003) 3.83
An empirical evaluation of genetic distance statistics using microsatellite data from bear (Ursidae) populations. Genetics (1997) 3.82
Continuously distributed factors affecting fitness. Genetics (1967) 3.76
THE MAINTENANCE OF ALLELES BY MUTATION. Genetics (1964) 3.68
Distribution of allelic frequencies in a finite population under stepwise production of neutral alleles. Proc Natl Acad Sci U S A (1975) 3.64
Mitochondrial DNA polymorphism reveals hidden heterogeneity within some Asian populations. Am J Hum Genet (1990) 3.64
Inferences of species phylogeny in relation to segregation of ancient polymorphisms. Genetics (1991) 3.63
Gene identity and genetic differentiation of populations in the finite island model. Genetics (1983) 3.58
Infinite allele model with varying mutation rate. Proc Natl Acad Sci U S A (1976) 3.56
Searching for missing heritability: designing rare variant association studies. Proc Natl Acad Sci U S A (2014) 3.47
Stepwise mutation model and distribution of allelic frequencies in a finite population. Proc Natl Acad Sci U S A (1978) 3.29
Genomic evolution during a 10,000-generation experiment with bacteria. Proc Natl Acad Sci U S A (1999) 3.27
The Genetic Structure of Natural Populations of DROSOPHILA MELANOGASTER. VII Synergistic Interaction of Spontaneous Mutant Polygenes Controlling Viability. Genetics (1969) 3.14
The population genetics of structural variation. Nat Genet (2007) 3.07
The study of genic variation by electrophoretic and heat denaturation techniques at the octanol dehydrogenase locus in members of the Drosophila virilis group. Genetics (1975) 2.82
Polyallelic random drift in relation to evolution. Proc Natl Acad Sci U S A (1966) 2.78
Statistical Studies on Protein Polymorphism in Natural Populations. III. Distribution of Allele Frequencies and the Number of Alleles per Locus. Genetics (1980) 2.76
Allelic and nonallelic homology of a supergene family. Proc Natl Acad Sci U S A (1982) 2.72
Selectionism and neutralism in molecular evolution. Mol Biol Evol (2005) 2.64
Tracing the source of campylobacteriosis. PLoS Genet (2008) 2.64
Models of evolution of reproductive isolation. Genetics (1983) 2.58
Simulating evolution by gene duplication. Genetics (1987) 2.52
Linkage disequilibrium due to random genetic drift in finite subdivided populations. Proc Natl Acad Sci U S A (1982) 2.45
Temporal analysis of archived samples indicates marked genetic changes in declining North Sea cod (Gadus morhua). Proc Biol Sci (2003) 2.42
Polymorphism and balancing selection at major histocompatibility complex loci. Genetics (1992) 2.34
Identifying genes of agronomic importance in maize by screening microsatellites for evidence of selection during domestication. Proc Natl Acad Sci U S A (2002) 2.29
Biases and reconciliation in estimates of linkage disequilibrium in the human genome. Am J Hum Genet (2006) 2.26
Intraspecific variation in population gene diversity and effective population size correlates with the mating system in plants. Proc Natl Acad Sci U S A (1991) 2.26
Estimation of effective population sizes from data on genetic markers. Philos Trans R Soc Lond B Biol Sci (2005) 2.25
Nucleotide diversity and linkage disequilibrium in loblolly pine. Proc Natl Acad Sci U S A (2004) 2.23
Gene and allelic genealogies at a gametophytic self-incompatibility locus. Genetics (1994) 2.19
The sensitivity of gel electrophoresis as a detector of genetic variation. Genetics (1979) 2.18
Revisiting an old riddle: what determines genetic diversity levels within species? PLoS Biol (2012) 2.15
Estimation of mutation rate from rare protein variants. Am J Hum Genet (1977) 2.15
Allelic variation in human mitochondrial genes based on patterns of restriction site polymorphism. Proc Natl Acad Sci U S A (1986) 2.13
Population amalgamation and genetic variation: observations on artificially agglomerated tribal populations of Central and South America. Am J Hum Genet (1988) 2.13
High MHC diversity maintained by balancing selection in an otherwise genetically monomorphic mammal. Proc Natl Acad Sci U S A (2004) 2.11
Best linear unbiased prediction of genomic breeding values using a trait-specific marker-derived relationship matrix. PLoS One (2010) 2.08
Population genetics of multigene families that are dispersed into two or more chromosomes. Proc Natl Acad Sci U S A (1983) 2.05
Drift as a mechanism for cultural change: an example from baby names. Proc Biol Sci (2003) 2.03
Genic heterogeneity within electrophoretic "alleles" and the pattern of variation among loci in Drosophila pseudoobscura. Genetics (1979) 2.02
Genomic prediction in animals and plants: simulation of data, validation, reporting, and benchmarking. Genetics (2012) 2.00
Selective constraint in protein polymorphism: study of the effectively neutral mutation model by using an improved pseudosampling method. Proc Natl Acad Sci U S A (1983) 1.98
Population genetic variation in gene expression is associated with phenotypic variation in Saccharomyces cerevisiae. Genome Biol (2004) 1.96
Drift and mutation with a finite number of allelic states. Proc Natl Acad Sci U S A (1984) 1.95
Rapid evolution and the importance of recombination to the gastroenteric pathogen Campylobacter jejuni. Mol Biol Evol (2008) 1.90
Microsatellite polymorphism in natural populations of the wild plant Arabidopsis thaliana. Genetics (1997) 1.89
Evolution of multigene families under interchromosomal gene conversion. Proc Natl Acad Sci U S A (1984) 1.88
Mutation rates, population sizes and amounts of electrophoretic variation of enzyme loci in natural populations. Genetics (1979) 1.85
Genomic signatures of selection at linked sites: unifying the disparity among species. Nat Rev Genet (2013) 1.85
A Mixed Model of Mutation for Electrophoretic Identity of Proteins within and between Populations. Genetics (1976) 1.82
Allele multiplicity in simple Mendelian disorders. Am J Hum Genet (1982) 1.82
Recombination within and between the human insulin and beta-globin gene loci. Proc Natl Acad Sci U S A (1983) 1.82
Historical genomics of North American maize. Proc Natl Acad Sci U S A (2012) 1.79
The genetic structure of natural populations of Drosophila melanogaster. 3. Dominance effect of spontaneous mutant polygenes controlling viability in heterozygous genetic backgrounds. Genetics (1965) 1.75
Fixation indices in subdivided populations. Genetics (1998) 1.69
Behavior of neutral mutants influenced by asociated overdominant loci in finite populations. Genetics (1971) 1.68
Genealogy of neutral genes and spreading of selected mutations in a geographically structured population. Genetics (1991) 1.66
Duplication/deletion polymorphism 5' - to the human beta globin gene. Nucleic Acids Res (1981) 1.65
Evidence of heterosis associated with an enzyme locus in a natural population of Drosophila. Proc Natl Acad Sci U S A (1970) 1.64
Microsatellite variation in North American populations of Drosophila melanogaster. Nucleic Acids Res (1995) 1.63
Statistical analyses of Drosophila and human protein polymorphisms. Proc Natl Acad Sci U S A (1975) 1.63
Selection in finite populations with multiple alleles. II. Centripetal selection, mutation, and isoallelic variation. Genetics (1970) 1.60
Maintenance of Genetic Variability under the Joint Effect of Mutation, Selection and Random Drift. Genetics (1978) 1.60
Intensity of natural selection at the major histocompatibility complex loci. Proc Natl Acad Sci U S A (1994) 1.59
Effects of metapopulation processes on measures of genetic diversity. Philos Trans R Soc Lond B Biol Sci (2000) 1.58
Quasispecies made simple. PLoS Comput Biol (2005) 1.56
Further studies on the Xavante Indians. X. Some hypotheses-generalizations resulting from these studies. Am J Hum Genet (1967) 1.55
Genetic diversity and population structure assessed by SSR and SNP markers in a large germplasm collection of grape. BMC Plant Biol (2013) 1.54
Genealogical structure among alleles regulating self-incompatibility in natural populations of flowering plants. Genetics (1997) 1.54
Polymorphism and the subunit structure of enzymes: a contribution to the neutralist-selectionist controversy. Proc Natl Acad Sci U S A (1977) 1.53
Contrasting histories of three gene regions associated with In(3L)Payne of Drosophila melanogaster. Genetics (1996) 1.51
Genetic diversity and fitness in small populations of partially asexual, self-incompatible plants. Heredity (Edinb) (2009) 1.49
Studies on genetic selection in a completely ascertained caucasian population. II. Family analyses of 11 blood group systems. Am J Hum Genet (1971) 1.46
A study on a nearly neutral mutation model in finite populations. Genetics (1991) 1.44
Analyses of the age of genes and the first arrival times in a finite population. Genetics (1983) 1.43
Maintenance of genetic variability under mutation and selection pressures in a finite population. Proc Natl Acad Sci U S A (1977) 1.41
Time for acquiring a new gene by duplication. Proc Natl Acad Sci U S A (1988) 1.40
Evolution in Mendelian Populations. Genetics (1931) 138.42
On the probability of fixation of mutant genes in a population. Genetics (1962) 18.38
Some possibilities for measuring selection intensities in man. Hum Biol (1958) 17.45
THE MUTATION LOAD IN SMALL POPULATIONS. Genetics (1963) 5.90
Evidence that the segregation-distortion phenomenon in Drosophila involves chromosome breakage. Proc Natl Acad Sci U S A (1962) 3.87
Stochastic processes and distribution of gene frequencies under natural selection. Cold Spring Harb Symp Quant Biol (1955) 3.69
The maintenance of super-numerary chromosomes in wild populations of Lilium callosum by preferential segregation. Genetics (1961) 1.67
2. The concept of genetic load: a reply. Am J Hum Genet (1963) 1.49
Inbreeding and homozygosis in bees. Genetics (1950) 1.38
The resistance of DDT-resistant Drosophila to other insecticides. Science (1951) 1.11
FUNDAMENTAL STUDIES ON CLINICAL CHEMISTRY. VII. JANOVSKY REACTION OF POLYNITRODIPHENYL COMPOUNDS. Chem Pharm Bull (Tokyo) (1964) 0.90
General theory of population genetics: synthesis. Cold Spring Harb Symp Quant Biol (1955) 0.90
Inhibition of formation of actiomycin by D-isoleucine. J Antibiot (Tokyo) (1960) 0.89
Population genetics. Am J Hum Genet (1961) 0.87
Paper partition chromatography of alcohols using the potassium xanthogenates. Nature (1951) 0.86
A comparison of fetal and infant death rates in the progeny of radiologists and pathologists. Am J Roentgenol Radium Ther Nucl Med (1955) 0.85
Ionizing radiation and evolution. Sci Am (1959) 0.82
Differences in susceptibility to ether in the virilis group of Drosophila. Genetics (1948) 0.76
Influence of antidiuretic hormone on adrenal cortical activity in rats. Jpn J Physiol (1954) 0.76
Poisoning by organic phosphate insecticides. Calif Med (1955) 0.76
Genetic considerations in establishing maximum radiation doses. Radiology (1957) 0.75
A consequence of the dominance hypothesis of hybrid vigor. Genetics (1948) 0.75
[The constituents of Convallaria. II. The isolation of desglucocheirotoxin]. Yakugaku Zasshi (1962) 0.75
[CLINICAL OBSERVATIONS AND PATHOLOGICAL STUDY OF 2 CASES OF AMYLOIDOSIS]. Saishin Igaku (1965) 0.75
A possible metabolic pathway of gamma-guanido- and gamma-guanido-beta-oxy-butyric acid by heteroarginase. Jpn J Pharmacol (1961) 0.75
Induced abortions in Japan in 1953-1954: a demographic analysis of reports from designated physicians. Milbank Mem Fund Q (1959) 0.75
Experimental studies on ovicidal substances occurring in human nightsoil. Exp Parasitol (1955) 0.75
CLINICAL AND SEROLOGICAL OBSERVATIONS ON THE CHILDREN GIVEN ATTENUATED MEASLES VACCINE. Acta Paediatr Jpn (1963) 0.75
ON THE TREATMENT OF SPINAL CORD INJURY: REVIEW AND ANALYSIS OF 2300 CASES. Nihon Seikeigeka Gakkai Zasshi (1964) 0.75
[CONSTITUENTS OF CONVALLARIA. 3. ISOLATION OF CHELIDONIC ACID]. Yakugaku Zasshi (1964) 0.75
Molecular pharmacological studies on drug-receptor complexes system in drug action. II. The mode of action of parathion on an acetylcholine receptor. Chem Pharm Bull (Tokyo) (1963) 0.75
Adrenocortical function of the patients with hypertension and with coronary heart diseases. Endocrinol Jpn (1960) 0.75
[Myocardial infarct]. Naika (1962) 0.75
[STATISTICAL OBSERVATIONS ON THE DEGREE OF CURVATURE OF THE CERVICAL VERTEBRAE]. Nihon Seikeigeka Gakkai Zasshi (1964) 0.75
TECHNIQUE FOR ACQUIRING AND PREPARING THE HUMAN TEMPORAL BONE FOR THE STUDY OF MIDDLE AND INNER EAR PATHOLOGY. Trans Am Acad Ophthalmol Otolaryngol (1965) 0.75
Molecular pharmacological studies on drug-receptor complexes system in drug action. I. antagonism to acetylcholine of organophosphorous compounds. Chem Pharm Bull (Tokyo) (1963) 0.75
[Studies on electrocardiography in work load. I. Study of a standard for electrocardiography in work load. II. On the radioelectrocardiograph]. Showa Igakkai Zasshi (1963) 0.75
[Colorimetric determination of pentoses. I. Comparative studies and improvement of various methods]. Yakugaku Zasshi (1962) 0.75
[FUNDAMENTAL STUDIES ON CLINICAL CHEMISTRY. IV. OXIDATION PRODUCTS OF CHOLESTEROL IN ACETONE WITH KILIANI'S REAGENT AND THEIR DERIVATIVES]. Yakugaku Zasshi (1964) 0.75
[THE EFFECTS OF HYPOTHERMIA ON THE ACTIVITY OF HEART AND OF ACTION OF THE CARDIAC AND DEPRESSOR NERVES IN URETHANE ANESTHETIZED RABBITS]. Fukuoka Igaku Zasshi (1963) 0.75
PEPTIDES FROM A TRYPTIC DIGEST OF BAKER'S YEAST CYTOCHROME C. Biochim Biophys Acta (1963) 0.75
Effect of injections of soluble antigen of the spleen size and antibody production in chickens. Anat Rec (1950) 0.75
A test for increased resistance in a chronically poisoned mouse population. Am J Hyg (1951) 0.75
[STUDY ON A NEW DIFFERENTIAL-CONFIRMATORY MEDIUM FOR THE FAMILY ENTEROBACTERIACEAE]. Nihon Saikingaku Zasshi (1964) 0.75
[CHRONIC PERITONITIS AND PERITONEAL DISEASES]. Naika (1963) 0.75
FUNDAMENTAL STUDIES ON CLINICAL CHEMISTRY. X. A NEW MICRO METHOD FOR THE COLORIMETRIC DETERMINATION OF URINARY DEHYDROEPIANDROSTERONE. Chem Pharm Bull (Tokyo) (1965) 0.75
Reaction between polynitrobenzene and active methylene groups. V. Jaffé and Baljet reactions. Pharm Bull (1955) 0.75
The absence of a primary sex factor on the X-chromosome of Drosophila. Am Nat (1947) 0.75
Statistic observation of the isolation culture of tubercle bacilli in sputum. Kekkaku (1951) 0.75
MOLECULAR PHARMACOLOGICAL STUDIES ON DRUG-RECEPTOR COMPLEXES SYSTEM IN DRUG ACTION. III. THE SITE OF ACTION OF ORGANOPHOSPHATE GROUP ON THE ACETYLCHOLINE RECEPTOR SURFACE. Chem Pharm Bull (Tokyo) (1964) 0.75
Chemicopharmacological studies on antispasmodic action. VI. On statistical treatment of concentration-action relationship of acetylcholine on small intestines of mice. Pharm Bull (1956) 0.75
[Application of chloramphenicol morpholine acetate in pediatrics]. J Antibiot B (1961) 0.75
[A cured case of obturator hernia]. Iryo (1961) 0.75
FUNDAMENTAL STUDIES ON CLINICAL CHEMISTRY. V. A SPECIFIC METHOD FOR THE DETERMINATION OF FREE CHOLESTEROL IN SERUM. Chem Pharm Bull (Tokyo) (1964) 0.75
Attenuative antidotal effects of guanidyl compounds on NH3 toxication. Jpn J Pharmacol (1961) 0.75
INACTIVATED MEASLES VIRUS VACCINE SUBSEQUENTLY CHALLENGED WITH LIVE ATTENUATED MEASLES VIRUS VACCINE. Jpn J Med Sci Biol (1965) 0.75
[New problems in traumatic neuroses]. Rinsho Geka (1962) 0.75
Reaction between polynitrobenzene and active methylene groups. IV. Reaction between 1-substituted 2,4,6-trinitrobenzene and acetone. Pharm Bull (1955) 0.75
FORMAL AND POPULATION GENETICS. Trans Am Acad Ophthalmol Otolaryngol (1965) 0.75
MOLECULAR PHARMACOLOGICAL STUDIES ON DRUG-RECEPTOR COMPLEXES SYSTEM IN DRUG ACTION. IV. RELATIONSHIP BETWEEN ANTICHOLINERGIC AND ANTICHOLINESTERASE ACTIVITIES OF ORGANOPHOSPHORYL CHOLINE DERIVATIVES BASED ON THEIR CHEMICAL STRUCTURE. Chem Pharm Bull (Tokyo) (1964) 0.75
FRACTIONATION OF PEPTIDES OBTAINED BY TRYPTIC HYDROLYSIS OF BAKER'S YEAST CYTOCHROME C. J Biochem (1964) 0.75
Chemicopharmacological studies on antispasmodic action. V. Fundamental conditions of bioassay of acetylcholine and atropine on the isolated small intestines of mice. Pharm Bull (1956) 0.75
[APPEARANCE AND TERMINATION OF CARDIAC FIBRILLATION]. Nisshin Igaku Jpn J Med Prog (1963) 0.75
Chromatography of arginine-containing peptides on a carboxylic acid resin. Biochim Biophys Acta (1959) 0.75
Occurrence of antidiuretic substance in human urine after heavy sweating. Jpn J Physiol (1953) 0.75
[A CASE OF ENCEPHALOPATHY INDUCED BY AMINOPYRINE HYPERSENSITIVITY]. Showa Igakkai Zasshi (1963) 0.75
[PULMONARY PARAGONIMIASIS]. Iryo (1964) 0.75
Studies on acylase activity and micro-organisms. XIX. Optical resolution of threonine. lvsine. trvptophan. and methionine by ucylase of soil bacteria. Chem Pharm Bull (Tokyo) (1962) 0.75
Chemicopharmacological studies on antispasmodic action. VIII. On the antagonistic action of atropine and its methobromide to acetylcholine with the isolated small intestines of mice. Pharm Bull (1957) 0.75
[Studies on the serum protein-bound polysaccharides in patients with cancer; especially on the possible site of their production]. Gan (1957) 0.75
[Clinical serological studies on weak live measles virus vaccine]. Paediatr Jpn (1963) 0.75
[CLINICAL EFFECTIVENESS OF VERINA (NYLIDRIN HYDROCHLORIDE)]. Chiryo (1963) 0.75
Recovery of a chemical fraction from human nightsoil having an ovistatic effect upon Ascaris lumbricoides eggs. Exp Parasitol (1955) 0.75