Synthesis of a fibrinolytic activator and inhibitor by endothelial cells.

PubWeight™: 2.83‹?› | Rank: Top 1%

🔗 View Article (PMC 431779)

Published in Proc Natl Acad Sci U S A on September 01, 1977

Authors

D J Loskutoff, T E Edgington

Articles citing this

Plasminogen activator and collagenase production by cultured capillary endothelial cells. J Cell Biol (1982) 2.33

Detection of an unusually stable fibrinolytic inhibitor produced by bovine endothelial cells. Proc Natl Acad Sci U S A (1983) 2.20

Organizational behavior of human umbilical vein endothelial cells. J Cell Biol (1982) 2.15

The opposing effects of basic fibroblast growth factor and transforming growth factor beta on the regulation of plasminogen activator activity in capillary endothelial cells. J Cell Biol (1987) 2.04

Degradation of connective tissue matrices by macrophages. I. Proteolysis of elastin, glycoproteins, and collagen by proteinases isolated from macrophages. J Exp Med (1980) 2.00

An endothelial cell-dependent pathway of coagulation. Proc Natl Acad Sci U S A (1985) 1.90

Distinct localizations of urokinase-type plasminogen activator and its type 1 inhibitor under cultured human fibroblasts and sarcoma cells. J Cell Biol (1987) 1.79

Binding of factors IX and IXa to cultured vascular endothelial cells. Proc Natl Acad Sci U S A (1983) 1.75

Natural anticoagulant mechanisms. J Clin Invest (1984) 1.75

Anti-cell surface pemphigus autoantibody stimulates plasminogen activator activity of human epidermal cells. A mechanism for the loss of epidermal cohesion and blister formation. J Exp Med (1983) 1.73

Human pulmonary endothelial cells in culture. Activities of cells from arteries and cells from veins. J Clin Invest (1980) 1.71

Participation of endothelial cells in the protein C-protein S anticoagulant pathway: the synthesis and release of protein S. J Cell Biol (1986) 1.68

Angiogenesis and rheumatoid arthritis: pathogenic and therapeutic implications. Ann Rheum Dis (1992) 1.65

Activation of rabbit Hageman factor by homogenates of cultured rabbit endothelial cells. J Clin Invest (1980) 1.53

Detection and partial characterization of an inhibitor of plasminogen activator in human platelets. J Clin Invest (1984) 1.50

Inhibition of tumor-cell-mediated extracellular matrix destruction by a fibroblast proteinase inhibitor, protease nexin I. Proc Natl Acad Sci U S A (1986) 1.47

Prognostic value of urokinase-type plasminogen activator (uPA) and plasminogen activator inhibitors PAI-1 and PAI-2 in breast carcinomas. Br J Cancer (1994) 1.43

Plasminogen activator secretion by granule neurons in cultures of developing cerebellum. Proc Natl Acad Sci U S A (1981) 1.43

Distribution of urokinase-type plasminogen activator immunoreactivity in the mouse. J Cell Biol (1984) 1.40

The vascular endothelium-pathobiologic significance. Am J Pathol (1978) 1.30

The role of nitric oxide as an endogenous regulator of platelet and neutrophil activation within the pulmonary circulation of the rabbit. Br J Pharmacol (1991) 1.28

Plasminogen activator inhibitor is associated with the extracellular matrix of cultured bovine smooth muscle cells. J Clin Invest (1987) 1.28

Plasminogen activator inhibitor-1 in acute hyperoxic mouse lung injury. J Clin Invest (1996) 1.25

Degradation of connective tissue matrices by macrophages. III. Morphological and biochemical studies on extracellular, pericellular, and intracellular events in matrix proteolysis by macrophages in culture. J Exp Med (1980) 1.25

Activation of endogenous factor V by a homocysteine-induced vascular endothelial cell activator. J Clin Invest (1986) 1.22

Effect of thrombin on the fibrinolytic activity of cultured bovine endothelial cells. J Clin Invest (1979) 1.20

Collagenase is a major gene product of induced rabbit synovial fibroblasts. J Cell Biol (1984) 1.20

Two different mechanisms in patients with venous thrombosis and defective fibrinolysis: low concentration of plasminogen activator or increased concentration of plasminogen activator inhibitor. Br Med J (Clin Res Ed) (1985) 1.19

Keratinocyte growth factor protects alveolar epithelium and endothelium from oxygen-induced injury in mice. Am J Pathol (1999) 1.19

Neutral protease secretion by human monocytes. Effect of surface-bound immune complexes. J Exp Med (1979) 1.18

Mechanism of dexamethasone inhibition of plasminogen activator in rat hepatoma cells. Proc Natl Acad Sci U S A (1978) 1.18

New insights into the coagulopathy of liver disease and liver transplantation. World J Gastroenterol (2006) 1.17

A coagulation pathway on bovine aortic segments leading to generation of Factor Xa and thrombin. J Clin Invest (1984) 1.15

Binding of tissue plasminogen activator to cultured human endothelial cells. J Clin Invest (1987) 1.15

Immunohistochemical localisation of tissue plasminogen activator and urokinase in the vessel wall. J Clin Pathol (1985) 1.13

Recovery of prostacyclin production by de-endothelialized rabbit aorta. Critical role of neointimal smooth muscle cells. J Clin Invest (1981) 1.11

Hormonal regulation of plasminogen activator in rat hepatoma cells. Mol Cell Biochem (1983) 1.08

Endothelial cells stimulated with tumor necrosis factor-alpha express varying amounts of tissue factor resulting in inhomogenous fibrin deposition in a native blood flow system. Effects of thrombin inhibitors. J Clin Invest (1994) 1.07

Binding of thrombin to subendothelial extracellular matrix. Protection and expression of functional properties. J Clin Invest (1989) 1.06

Expression of the urokinase receptor in vascular endothelial cells is stimulated by basic fibroblast growth factor. J Cell Biol (1991) 1.06

Anchorage independent growth and plasminogen activator production by bovine endothelial cells. J Cell Biol (1980) 1.02

Rabbit beta-migrating very low density lipoprotein increases endothelial macromolecular transport without altering electrical resistance. J Clin Invest (1986) 1.02

Vein contraction and smooth muscle cell extensions as causes of endothelial damage during graft preparation. Ann Surg (1981) 1.00

von Willebrand factor antigen and plasminogen activator inhibitor in giant cell arteritis. Ann Rheum Dis (1991) 0.99

Differences in intracellular distribution of plasminogen activator in growing, confluent, and transformed 3T3 cells. Proc Natl Acad Sci U S A (1979) 0.99

Phorbol ester and mitogens stimulate human fibroblast secretions of plasmin-activatable plasminogen activator and protease nexin, an antiactivator/antiplasmin. J Cell Biol (1983) 0.98

Immunological characterisation of plasminogen activators in the human vessel wall. J Clin Pathol (1983) 0.92

Cellular processing of bovine factors X and Xa by cultured bovine aortic endothelial cells. J Exp Med (1985) 0.91

Interaction of plasmin with endothelial cells. Biochem J (1984) 0.91

Thrombin neutralizes plasminogen activator inhibitor 1 (PAI-1) that is complexed with vitronectin in the endothelial cell matrix. J Cell Biol (1991) 0.91

Plasminogen activator inhibitor type I stabilizes vitronectin-dependent adhesions in HT-1080 cells. J Cell Biol (1990) 0.88

Significance of raised plasma concentrations of tissue-type plasminogen activator and plasminogen activator inhibitor in patients at risk from ischaemic heart disease. Br Heart J (1994) 0.87

Cerebrospinal fluid plasminogen activator inhibitor-1 in patients with neurological disease. J Clin Pathol (1997) 0.87

Smooth muscle and endothelial cell function in the pathogenesis of atherosclerosis. Can Med Assoc J (1982) 0.87

A fast-acting elastase inhibitor in human monocytes. J Exp Med (1985) 0.86

Distinct transformation phenotypes induced by polyoma virus and simian virus 40 in rat fibroblasts and their control by an early viral gene function. J Virol (1980) 0.86

Borrelia burgdorferi induces secretion of pro-urokinase-type plasminogen activator by human monocytes. Infect Immun (1996) 0.85

Endothelial cell-mediated conversion of Glu-plasminogen to Lys-plasminogen. Further evidence for assembly of the fibrinolytic system on the endothelial cell surface. J Clin Invest (1988) 0.84

Role of plasminogen activator inhibitor in the reciprocal regulation of bovine aortic endothelial and smooth muscle cell migration by TGF-beta 1. Am J Pathol (1996) 0.83

Perturbation of human endothelial cells by thrombin or PMA changes the reactivity of their extracellular matrix towards platelets. J Cell Biol (1987) 0.83

Fibrinogen degradation product fragment D induces endothelial cell detachment by activation of cell-mediated fibrinolysis. J Clin Invest (1992) 0.82

Plasminogen activation transforms the morphology of quiescent 3T3 cell monolayers and initiates growth. Br J Cancer (1979) 0.82

Aspirin inhibits vascular plasminogen activator activity in vivo. Studies utilizing a new assay to quantify plasminogen activator activity. J Clin Invest (1984) 0.80

Modulation of plasminogen activator secretion by activated macrophages: influence of serum factors and correlation with tumoricidal potential. Proc Natl Acad Sci U S A (1979) 0.80

Bovine aortic endothelial cells elaborate an inhibitor of the generation of lipopolysaccharide-stimulated human blood monocyte procoagulant activity. J Clin Invest (1984) 0.78

Beta-amyloidolysis and glutathione in Alzheimer's disease. J Blood Med (2013) 0.77

Potential proteolytic activity of human plasma fibronectin. Proc Natl Acad Sci U S A (1986) 0.76

Transformation phenotype of polyoma virus-transformed rat fibroblasts: plasminogen activator production is modulated by the growth state of the cells and regulated by the expression of an early viral gene function. J Virol (1980) 0.76

Preparation of venous allografts. A comparison of techniques. Ann Surg (1984) 0.75

Normal and abnormal hemostasis--an integrated view. A review. Am J Pathol (1978) 0.75

Effect of a prostaglandin I(2) analog on the expression of thrombomodulin in liver and spleen endothelial cells after an extensive hepatectomy. Surg Today (2011) 0.75

Articles cited by this

Protein measurement with the Folin phenol reagent. J Biol Chem (1951) 1743.91

A method of trace iodination of proteins for immunologic studies. Int Arch Allergy Appl Immunol (1966) 43.66

Plasminogen: purification from human plasma by affinity chromatography. Science (1970) 11.72

Synthesis of antihemophilic factor antigen by cultured human endothelial cells. J Clin Invest (1973) 10.18

Secretion of plasminogen activator by stimulated macrophages. J Exp Med (1974) 8.82

Culture of vascular endothelium. Prog Hemost Thromb (1976) 7.05

The histological localisation of fibrinolysin activator. J Pathol Bacteriol (1959) 5.99

An enzymatic function associated with transformation of fibroblasts by oncogenic viruses. I. Chick embryo fibroblast cultures transformed by avian RNA tumor viruses. J Exp Med (1973) 5.53

Restoration of contact-inhibited growth to transformed cells by dibutyryl adenosine 3':5'-cyclic monophosphate. Proc Natl Acad Sci U S A (1971) 3.44

Angiotensin-converting enzyme: vascular endothelial localization. Science (1976) 3.22

Macrophage plasminogen activator: modulation of enzyme production by anti-inflammatory steroids, mitotic inhibitors, and cyclic nucleotides. Cell (1976) 3.13

Synthesis of von Willebrand factor by cultured human endothelial cells. Proc Natl Acad Sci U S A (1974) 2.83

Tumour promotor induces plasminogen activator. Nature (1976) 2.60

Hormone and neurotransmitter receptors in an established vascular endothelial cell line. Proc Natl Acad Sci U S A (1976) 2.40

Angiotensin II stimulation of prostaglandin production in cultured human vascular endothelium. Science (1975) 2.24

Cocarcinogenic principles from the seed oil of Croton tiglium and from other Euphorbiaceae. Cancer Res (1968) 2.07

ACTIVATION OF PROPLASMIN BY A FACTOR FROM MAMMALIAN TISSUE. J Clin Invest (1950) 1.95

Ovarian plasminogen activator: relationship to ovulation and hormonal regulation. Cell (1975) 1.93

The preparation of human fibrinogen free of plasminogen. Biochim Biophys Acta (1962) 1.84

The endothelial cell. Br Med J (1966) 1.75

Association of a protease (plasminogen activator) with a specific membrane fraction isolated from transformed cells. J Cell Biol (1976) 1.69

Effect of a phorbol ester on a transformation-sensitive surface protein of chick fibroblasts. Nature (1976) 1.48

FIBRIONLYTIC ACTIVITY OF VASCULAR ENDOTHELIUM. Br Med Bull (1964) 1.41

An alternative pathway for fibrinolysis. I. The cleavage of fibrinogen by leukocyte proteases at physiologic pH. J Clin Invest (1975) 1.36

STUDIES ON THE TISSUE ACTIVATOR OF PLASMINOGEN. DISTRIBUTION OF ACTIVATOR AND PROTEOLYTIC ACTIVITY IN THE SUBCELLULAR FRACTIONS OF RABBIT KIDNEY. Biochem J (1965) 1.23

Tissue fibrinolytic activity studied by a histochemical method. Fed Proc (1990) 1.15

Lack of correlation between fibrinolysis and the transformed state of cultured mammalian cells. Biochem Biophys Res Commun (1974) 1.10

Effect of prednisolone on the coagulation and fibrinolytic systems. Scand J Haematol (1970) 1.01

The extraction and separation of activators and inhibitors of fibrinolysis from bovine endothelium and mesothelium. Br J Haematol (1970) 0.98

Thromboplastin and plasminogen activator in tissues of the rabbit. Am J Physiol (1970) 0.95

Phorbol-12-myristate-13-acetate effect on cyclic adenosine 3',5'-monophosphate levels in mouse skin and inhibition of phorbol-myristate-acetate-promoted tumorigenesis by theophylline. Cancer Res (1974) 0.92

Properties of cultured endothelial cells. Ser Haematol (1973) 0.90

The physiology of fibrinolysis. Med Clin North Am (1972) 0.88

Plasminogen activator from human embryonic kidney cell cultures. Evidence for a proactivator. Biochim Biophys Acta (1977) 0.85

Histochemical study of an inhibitor of fibrinolysis in the human arterial wall. Nature (1974) 0.84

Localization and distribution of fibrinolysis inhibition in the walls of human arteries and veins. Thromb Res (1977) 0.83

Articles by these authors

(truncated to the top 100)

An assay for transforming growth factor-beta using cells transfected with a plasminogen activator inhibitor-1 promoter-luciferase construct. Anal Biochem (1994) 6.31

Bacterial lipopolysaccharide and inflammatory mediators augment IL-6 secretion by human endothelial cells. J Immunol (1989) 3.01

Identification of regulatory sequences in the type 1 plasminogen activator inhibitor gene responsive to transforming growth factor beta. J Biol Chem (1991) 2.52

Endothelial cells produce a latent inhibitor of plasminogen activators that can be activated by denaturants. J Biol Chem (1985) 2.23

Purification of an inhibitor of plasminogen activator (antiactivator) synthesized by endothelial cells. J Biol Chem (1984) 2.22

Is plasminogen activator inhibitor-1 the molecular switch that governs urokinase receptor-mediated cell adhesion and release? J Cell Biol (1996) 2.21

Detection of an unusually stable fibrinolytic inhibitor produced by bovine endothelial cells. Proc Natl Acad Sci U S A (1983) 2.20

Cytokine activation of vascular endothelium. Effects on tissue-type plasminogen activator and type 1 plasminogen activator inhibitor. J Biol Chem (1988) 2.04

Regulation of mRNAs for type-1 plasminogen activator inhibitor, fibronectin, and type I procollagen by transforming growth factor-beta. Divergent responses in lung fibroblasts and carcinoma cells. J Biol Chem (1988) 1.93

Regulation of type 1 plasminogen activator inhibitor gene expression in cultured bovine aortic endothelial cells. Induction by transforming growth factor-beta, lipopolysaccharide, and tumor necrosis factor-alpha. J Biol Chem (1989) 1.92

Elevated expression of transforming growth factor-beta in adipose tissue from obese mice. Mol Med (1997) 1.92

Regulation of the fibrinolytic system of cultured human vascular endothelium by interleukin 1. J Clin Invest (1986) 1.89

Cloning and sequence of a cDNA coding for the human beta-migrating endothelial-cell-type plasminogen activator inhibitor. Proc Natl Acad Sci U S A (1986) 1.85

Regulation of murine type 1 plasminogen activator inhibitor gene expression in vivo. Tissue specificity and induction by lipopolysaccharide, tumor necrosis factor-alpha, and transforming growth factor-beta. J Clin Invest (1991) 1.85

Cultured bovine endothelial cells produce both urokinase and tissue-type plasminogen activators. J Cell Biol (1982) 1.77

Increased type 1 plasminogen activator inhibitor gene expression in atherosclerotic human arteries. Proc Natl Acad Sci U S A (1992) 1.76

Distribution and regulation of plasminogen activator inhibitor-1 in murine adipose tissue in vivo. Induction by tumor necrosis factor-alpha and lipopolysaccharide. J Clin Invest (1996) 1.65

Type 1 plasminogen activator inhibitor gene: functional analysis and glucocorticoid regulation of its promoter. Proc Natl Acad Sci U S A (1988) 1.64

Reverse fibrin autography: a method to detect and partially characterize protease inhibitors after sodium dodecyl sulfate--polyacrylamide gel electrophoresis. Anal Biochem (1984) 1.59

Activation of rabbit Hageman factor by homogenates of cultured rabbit endothelial cells. J Clin Invest (1980) 1.53

Cellular localization of type 1 plasminogen activator inhibitor messenger RNA and protein in murine renal tissue. Am J Pathol (1993) 1.52

Changes in procoagulant and fibrinolytic gene expression during bleomycin-induced lung injury in the mouse. J Clin Invest (1995) 1.52

Detection and partial characterization of an inhibitor of plasminogen activator in human platelets. J Clin Invest (1984) 1.50

Type 1 plasminogen activator inhibitor. Prog Hemost Thromb (1989) 1.49

Murine CD14 gene expression in vivo: extramyeloid synthesis and regulation by lipopolysaccharide. J Exp Med (1995) 1.46

The primary plasminogen-activator inhibitors in endothelial cells, platelets, serum, and plasma are immunologically related. Proc Natl Acad Sci U S A (1985) 1.46

Murine tissue factor gene expression in vivo. Tissue and cell specificity and regulation by lipopolysaccharide. Am J Pathol (1993) 1.45

Tissue factor gene expression in the adipose tissues of obese mice. Proc Natl Acad Sci U S A (1998) 1.44

Leptin-dependent platelet aggregation and arterial thrombosis suggests a mechanism for atherothrombotic disease in obesity. J Clin Invest (2001) 1.41

Plasminogen activator inhibitor-1 and its cofactor vitronectin stabilize arterial thrombi after vascular injury in mice. Circulation (2001) 1.39

Gene expression during the development of Bacillus subtilis bacteriophage phi 29. I. Analysis of viral-specific transcription by deoxyribonucleic acid-ribonucleic acid competition hybridization. J Virol (1973) 1.38

Structural and functional analysis of the plasminogen activator inhibitor-1 binding motif in the somatomedin B domain of vitronectin. J Biol Chem (1996) 1.31

Tissue distribution and regulation of murine von Willebrand factor gene expression in vivo. Blood (1998) 1.29

Fibrin deposition in tissues from endotoxin-treated mice correlates with decreases in the expression of urokinase-type but not tissue-type plasminogen activator. J Clin Invest (1996) 1.29

Distinct antithrombotic consequences of platelet glycoprotein Ibalpha and VI deficiency in a mouse model of arterial thrombosis. J Thromb Haemost (2006) 1.28

Activated protein C stimulates the fibrinolytic activity of cultured endothelial cells and decreases antiactivator activity. Proc Natl Acad Sci U S A (1985) 1.27

Human melanoma cells derived from lymphatic metastases use integrin alpha v beta 3 to adhere to lymph node vitronectin. J Clin Invest (1992) 1.26

The fibrinolytic system of the vascular wall. Clin Haematol (1985) 1.25

Tissue distribution of factor VIII gene expression in vivo--a closer look. Thromb Haemost (2001) 1.24

Plasminogen activator inhibitor-1 regulates cell adhesion by binding to the somatomedin B domain of vitronectin. J Cell Physiol (2001) 1.23

Tumor necrosis factor alpha is a key component in the obesity-linked elevation of plasminogen activator inhibitor 1. Proc Natl Acad Sci U S A (1999) 1.23

Comparative studies of the fibrinolytic activity of cultured vascular cells. Thromb Res (1979) 1.22

Evidence that type 1 plasminogen activator inhibitor binds to the somatomedin B domain of vitronectin. J Biol Chem (1991) 1.21

Coordinated induction of plasminogen activator inhibitor-1 (PAI-1) and inhibition of plasminogen activator gene expression by hypoxia promotes pulmonary vascular fibrin deposition. J Clin Invest (1998) 1.20

Extracellular matrix of cultured bovine aortic endothelial cells contains functionally active type 1 plasminogen activator inhibitor. Blood (1987) 1.20

Purification of a protein from bovine plasma that binds to type 1 plasminogen activator inhibitor and prevents its interaction with extracellular matrix. Evidence that the protein is vitronectin. J Biol Chem (1989) 1.20

Effect of thrombin on the fibrinolytic activity of cultured bovine endothelial cells. J Clin Invest (1979) 1.20

Tissue factor expression during human and mouse development. Am J Pathol (1996) 1.19

The somatomedin B domain of vitronectin. Structural requirements for the binding and stabilization of active type 1 plasminogen activator inhibitor. J Biol Chem (1994) 1.18

Mechanism of protein C-dependent clot lysis: role of plasminogen activator inhibitor. Blood (1986) 1.15

Human endothelial cells produce IL-6. Lack of responses to exogenous IL-6. Ann N Y Acad Sci (1989) 1.12

Replication of dengue and junin viruses in cultured rabbit and human endothelial cells. Infect Immun (1978) 1.12

Gene expression during the development of Bacillus subtilis bacteriophage phi29. II. Resolution of viral-specific ribonucleic acid molecules. J Virol (1973) 1.12

Serum-mediated suppression of cell-associated plasminogen activator activity in cultured endothelial cells. Cell (1980) 1.11

Tissue distribution and regulation of plasminogen activator inhibitor-1 in obese mice. Mol Med (1996) 1.10

Immunoradiometric assay to measure the binding of a specific inhibitor to tissue-type plasminogen activator. J Lab Clin Med (1985) 1.09

Detection of vitronectin mRNA in tissues and cells of the mouse. Proc Natl Acad Sci U S A (1991) 1.09

Kinetic analysis of the interactions between plasminogen activator inhibitor 1 and both urokinase and tissue plasminogen activator. Arch Biochem Biophys (1988) 1.08

Insulin continues to induce plasminogen activator inhibitor 1 gene expression in insulin-resistant mice and adipocytes. Mol Med (2000) 1.08

Effects of acidified fetal bovine serum on the fibrinolytic activity and growth of cells in culture. J Cell Physiol (1978) 1.06

Inactivation of plasminogen activator inhibitor by oxidants. Biochemistry (1986) 1.04

Astrocytes are the primary source of tissue factor in the murine central nervous system. A role for astrocytes in cerebral hemostasis. J Clin Invest (1993) 1.04

Expression of type 1 plasminogen activator inhibitor in chronic pulmonary thromboemboli. Circulation (1994) 1.04

SPARC induces the expression of type 1 plasminogen activator inhibitor in cultured bovine aortic endothelial cells. J Biol Chem (1991) 1.02

An inhibitor of plasminogen activator in rabbit endothelial cells. J Biol Chem (1981) 1.01

Binding of type 1 plasminogen activator inhibitor to the extracellular matrix of cultured bovine endothelial cells. J Biol Chem (1989) 1.01

Expression of fibrinolytic genes in atherosclerotic abdominal aortic aneurysm wall. A possible mechanism for aneurysm expansion. J Clin Invest (1995) 1.00

Kinetic analysis of the interaction between type 1 plasminogen activator inhibitor and vitronectin and evidence that the bovine inhibitor binds to a thrombin-derived amino-terminal fragment of bovine vitronectin. Biochim Biophys Acta (1991) 1.00

Disruption of the plasminogen activator inhibitor 1 gene reduces the adiposity and improves the metabolic profile of genetically obese and diabetic ob/ob mice. FASEB J (2001) 0.99

Cultured granulosa cells produce two plasminogen activators and an antiactivator, each regulated differently by gonadotropins. Endocrinology (1985) 0.99

Induction of plasminogen activator inhibitor 1 gene expression in murine liver by lipopolysaccharide. Cellular localization and role of endogenous tumor necrosis factor-alpha. Am J Pathol (1997) 0.99

Fibrinolytic system of vascular endothelial cells. Role of plasminogen activator inhibitors. Haemostasis (1988) 0.99

The majority of type 1 plasminogen activator inhibitor associated with cultured human endothelial cells is located under the cells and is accessible to solution-phase tissue-type plasminogen activator. J Cell Biol (1990) 0.98

Characterization of two monoclonal antibodies against human tissue-type plasminogen activator. Thromb Haemost (1985) 0.96

Distribution of vitronectin mRNA during murine development. Dev Dyn (1995) 0.95

Altered expression of plasminogen activator inhibitor type 1 in placentas from pregnant women with preeclampsia and/or intrauterine fetal growth retardation. Blood (1994) 0.94

Dysfunction of glomerular fibrinolysis in experimental antiglomerular basement membrane antibody glomerulonephritis. J Am Soc Nephrol (1993) 0.93

The dexamethasone-induced inhibitor of plasminogen activator in hepatoma cells is antigenically-related to an inhibitor produced by bovine aortic endothelial cells. Thromb Haemost (1986) 0.92

Messenger RNA for plasminogen activator inhibitor. Thromb Res (1986) 0.92

Abnormal expression of type 1 plasminogen activator inhibitor and tissue factor in severe preeclampsia. Thromb Haemost (1998) 0.91

Endotoxin stimulates expression of the murine urokinase receptor gene in vivo. Am J Pathol (1995) 0.91

Interactions between type 1 plasminogen activator inhibitor, extracellular matrix and vitronectin. Cell Differ Dev (1990) 0.91

Role of tumor necrosis factor alpha in induction of murine CD14 gene expression by lipopolysaccharide. Infect Immun (1997) 0.91

Regulation of tissue factor gene expression in obesity. Blood (2001) 0.90

Serum-derived vitronectin influences the pericellular distribution of type 1 plasminogen activator inhibitor. J Cell Biol (1990) 0.89

The kidneys of mice with autoimmune disease acquire a hypofibrinolytic/procoagulant state that correlates with the development of glomerulonephritis and tissue microthrombosis. Am J Pathol (1997) 0.89

Intracellular plasminogen activator activity in growing and quiescent cells. J Cell Physiol (1978) 0.89

Changes in the plasma levels of type 1 and type 2 plasminogen activator inhibitors in normal pregnancy and in patients with severe preeclampsia. Blood (1989) 0.89

The leptin receptor system of human platelets. J Thromb Haemost (2005) 0.88

Expression of transforming growth factor-beta and tumor necrosis factor-alpha in the plasma and tissues of mice with lupus nephritis. Lab Invest (2000) 0.88

Type 1 plasminogen activator inhibitor induces multimerization of plasma vitronectin. A suggested mechanism for the generation of the tissue form of vitronectin in vivo. J Biol Chem (1996) 0.87

Interactions between fibrin and the plasminogen activators produced by cultured endothelial cells. Blood (1983) 0.87

Localization of vitronectin in the normal and atherosclerotic human vessel wall. Histochem Cell Biol (1997) 0.87

Protein C inhibitor is expressed in tubular cells of human kidney. J Clin Invest (1994) 0.86

Fibrinolytic pathways and the endothelium. Semin Thromb Hemost (1987) 0.86

Extrahepatic expression and regulation of protein C in the mouse. Am J Pathol (1998) 0.86

Platelets stimulate endothelial cells to synthesize type 1 plasminogen activator inhibitor. Evaluation of the role of transforming growth factor beta. Blood (1991) 0.85

Vitronectin gene expression in vivo. Evidence for extrahepatic synthesis and acute phase regulation. J Biol Chem (1994) 0.85

The PAI-1/vitronectin interaction: two cats in a bag? Thromb Haemost (1995) 0.85

Expression and cellular localization of messenger RNA for plasminogen activator inhibitor type 1 in human astrocytomas in vivo. Cancer Res (1994) 0.85