Published in J Cell Biol on September 01, 1982
Plasminogen activator and collagenase production by cultured capillary endothelial cells. J Cell Biol (1982) 2.33
Filovirus-induced endothelial leakage triggered by infected monocytes/macrophages. J Virol (1996) 2.26
Detection of an unusually stable fibrinolytic inhibitor produced by bovine endothelial cells. Proc Natl Acad Sci U S A (1983) 2.20
In vitro angiogenesis on the human amniotic membrane: requirement for basic fibroblast growth factor-induced proteinases. J Cell Biol (1989) 2.05
The opposing effects of basic fibroblast growth factor and transforming growth factor beta on the regulation of plasminogen activator activity in capillary endothelial cells. J Cell Biol (1987) 2.04
Latent tissue plasminogen activator produced by human endothelial cells in culture: evidence for an enzyme-inhibitor complex. Proc Natl Acad Sci U S A (1983) 1.98
Generation in plasma of a fast-acting inhibitor of plasminogen activator in response to endotoxin stimulation. J Clin Invest (1985) 1.97
Endotoxin enhances tissue factor and suppresses thrombomodulin expression of human vascular endothelium in vitro. J Clin Invest (1987) 1.74
Interleukin 1 induces endothelial cell synthesis of plasminogen activator inhibitor. J Exp Med (1986) 1.68
Detection and partial characterization of an inhibitor of plasminogen activator in human platelets. J Clin Invest (1984) 1.50
Correlation of cell migration, cell invasion, receptor number, proteinase production, and basic fibroblast growth factor levels in endothelial cells. J Cell Biol (1990) 1.37
Urokinase-type plasminogen activator is induced in migrating capillary endothelial cells. J Cell Biol (1987) 1.35
Activated protein C stimulates the fibrinolytic activity of cultured endothelial cells and decreases antiactivator activity. Proc Natl Acad Sci U S A (1985) 1.27
Thrombin stimulates tissue plasminogen activator release from cultured human endothelial cells. J Clin Invest (1984) 1.21
Binding of tissue plasminogen activator to cultured human endothelial cells. J Clin Invest (1987) 1.15
Immunohistochemical localisation of tissue plasminogen activator and urokinase in the vessel wall. J Clin Pathol (1985) 1.13
Characterization of an apically derived epithelial membrane glycoprotein from bovine milk, which is expressed in capillary endothelia in diverse tissues. J Cell Biol (1985) 0.98
Urokinase-type plasminogen activator in endothelial cells during acute inflammation of the appendix. Am J Pathol (1989) 0.91
Endothelial cell-mediated conversion of Glu-plasminogen to Lys-plasminogen. Further evidence for assembly of the fibrinolytic system on the endothelial cell surface. J Clin Invest (1988) 0.84
Production of plasminogen activator in cultures of superior cervical ganglia and isolated Schwann cells. Proc Natl Acad Sci U S A (1985) 0.83
Fibrinogen degradation product fragment D induces endothelial cell detachment by activation of cell-mediated fibrinolysis. J Clin Invest (1992) 0.82
Identification and partial characterization of two major proteins of Mr 47,000 synthesized by bovine retinal endothelial cells in culture. Biochem J (1987) 0.80
Deficiency of plasminogen activator inhibitor 2 in plasma of patients with hereditary angioedema with normal C1 inhibitor levels. J Allergy Clin Immunol (2015) 0.80
Role of plasminogen activator in pemphigus vulgaris. Am J Pathol (1989) 0.79
Decreased fibrinolytic activity in porcine-to-primate cardiac xenotransplantation. Mol Med (1998) 0.79
Stimulation of tissue plasminogen activator production by retinoic acid: synergistic effect on protein kinase C-mediated activation. Blood (1992) 0.76
Effects of sulfonylureas on the synthesis and secretion of plasminogen activator from bovine aortic endothelial cells. J Clin Invest (1988) 0.76
Transforming Growth Factor-β1 Modulates the Expression of Syndecan-4 in Cultured Vascular Endothelial Cells in a Biphasic Manner. J Cell Biochem (2016) 0.75
Induction of Syndecan-4 by Organic-Inorganic Hybrid Molecules with a 1,10-Phenanthroline Structure in Cultured Vascular Endothelial Cells. Int J Mol Sci (2017) 0.75
Plasminogen activators in ischemic stroke: introduction. Stroke (2010) 0.75
Production of plasminogen activator by alveolar macrophages in normal subjects and patients with interstitial lung disease. Thorax (1988) 0.75
Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem (1976) 903.81
Plasminogen: purification from human plasma by affinity chromatography. Science (1970) 11.72
The histological localisation of fibrinolysin activator. J Pathol Bacteriol (1959) 5.99
A study of proteases and protease-inhibitor complexes in biological fluids. J Exp Med (1978) 3.92
Culture of arterial endothelial cells: characterization and growth of bovine aortic cells. Thromb Diath Haemorrh (1975) 3.68
Factors involved in the modulation of cell proliferation in vivo and in vitro: the role of fibroblast and epidermal growth factors in the proliferative response of mammalian cells. In Vitro (1978) 3.57
On the regulation and control of fibrinolysis. Edward Kowalski Memorial Lecture. Thromb Haemost (1980) 3.44
Purification and characterization of the plasminogen activator secreted by human melanoma cells in culture. J Biol Chem (1981) 2.80
The peptide chains of human plasmin. Mechanism of activation of human plasminogen to plasmin. J Biol Chem (1967) 2.01
The preparation of human fibrinogen free of plasminogen. Biochim Biophys Acta (1962) 1.84
Phorbol ester-induced morphological changes in transformed chick fibroblasts: evidence for direct catalytic involvement of plasminogen activator. Cell (1979) 1.69
Tissue activators of plasminogen. Fed Proc (1990) 1.62
Molecular species of plasminogen activators secreted by normal and neoplastic human cells. Cancer Res (1980) 1.49
Thrombolysis by human tissue plasminogen activator and urokinase in rabbits with experimental pulmonary embolus. Nature (1981) 1.45
Purification and characterization of human vascular plasminogen activator derived from blood vessel perfusates. J Biol Chem (1979) 1.39
Comparative studies of the fibrinolytic activity of cultured vascular cells. Thromb Res (1979) 1.22
Effect of thrombin on the fibrinolytic activity of cultured bovine endothelial cells. J Clin Invest (1979) 1.20
Immunological characterization of multiple weight forms of human cell plasminogen activators. J Biol Chem (1979) 1.20
Immunological characterization of plasminogen activator activities in human tissues and body fluids. J Lab Clin Med (1981) 1.17
Fibrinogenolysis and fibrinolysis with tissue plasminogen activator, urokinase, streptokinase-activated human globulin, and plasmin. Proc Soc Exp Biol Med (1971) 1.12
Secretion of plasminogen activators by cultured bovine endothelial cells: partial purification, characterization and evidence for multiple forms. Thromb Haemost (1981) 1.00
Correlation between a specific molecular weight form of plasminogen activator and metabolic activity of 3T3 cells. J Cell Biol (1981) 0.98
Human urokinase and porcine tissue plasminogen activator. A comparative study of the mechanism of fibrinolysis, and the effect of natural proteinase inhibitors and omega-aminocarboxylic acids. Dan Med Bull (1977) 0.86
A variant vascular endothelial cell line with altered growth characteristics. J Cell Physiol (1979) 0.81
Purification and some properties of urokinase. Thromb Diath Haemorrh (1975) 0.80
An assay for transforming growth factor-beta using cells transfected with a plasminogen activator inhibitor-1 promoter-luciferase construct. Anal Biochem (1994) 6.31
Bacterial lipopolysaccharide and inflammatory mediators augment IL-6 secretion by human endothelial cells. J Immunol (1989) 3.01
Synthesis of a fibrinolytic activator and inhibitor by endothelial cells. Proc Natl Acad Sci U S A (1977) 2.83
Identification of regulatory sequences in the type 1 plasminogen activator inhibitor gene responsive to transforming growth factor beta. J Biol Chem (1991) 2.52
Endothelial cells produce a latent inhibitor of plasminogen activators that can be activated by denaturants. J Biol Chem (1985) 2.23
Purification of an inhibitor of plasminogen activator (antiactivator) synthesized by endothelial cells. J Biol Chem (1984) 2.22
Is plasminogen activator inhibitor-1 the molecular switch that governs urokinase receptor-mediated cell adhesion and release? J Cell Biol (1996) 2.21
Detection of an unusually stable fibrinolytic inhibitor produced by bovine endothelial cells. Proc Natl Acad Sci U S A (1983) 2.20
Cytokine activation of vascular endothelium. Effects on tissue-type plasminogen activator and type 1 plasminogen activator inhibitor. J Biol Chem (1988) 2.04
Latent tissue plasminogen activator produced by human endothelial cells in culture: evidence for an enzyme-inhibitor complex. Proc Natl Acad Sci U S A (1983) 1.98
Regulation of mRNAs for type-1 plasminogen activator inhibitor, fibronectin, and type I procollagen by transforming growth factor-beta. Divergent responses in lung fibroblasts and carcinoma cells. J Biol Chem (1988) 1.93
A potential basis for the thrombotic risks associated with lipoprotein(a). Nature (1989) 1.93
Regulation of type 1 plasminogen activator inhibitor gene expression in cultured bovine aortic endothelial cells. Induction by transforming growth factor-beta, lipopolysaccharide, and tumor necrosis factor-alpha. J Biol Chem (1989) 1.92
Elevated expression of transforming growth factor-beta in adipose tissue from obese mice. Mol Med (1997) 1.92
Regulation of the fibrinolytic system of cultured human vascular endothelium by interleukin 1. J Clin Invest (1986) 1.89
Local abnormalities in coagulation and fibrinolytic pathways predispose to alveolar fibrin deposition in the adult respiratory distress syndrome. J Clin Invest (1989) 1.88
Cloning and sequence of a cDNA coding for the human beta-migrating endothelial-cell-type plasminogen activator inhibitor. Proc Natl Acad Sci U S A (1986) 1.85
Regulation of murine type 1 plasminogen activator inhibitor gene expression in vivo. Tissue specificity and induction by lipopolysaccharide, tumor necrosis factor-alpha, and transforming growth factor-beta. J Clin Invest (1991) 1.85
Increased type 1 plasminogen activator inhibitor gene expression in atherosclerotic human arteries. Proc Natl Acad Sci U S A (1992) 1.76
Distribution and regulation of plasminogen activator inhibitor-1 in murine adipose tissue in vivo. Induction by tumor necrosis factor-alpha and lipopolysaccharide. J Clin Invest (1996) 1.65
Type 1 plasminogen activator inhibitor gene: functional analysis and glucocorticoid regulation of its promoter. Proc Natl Acad Sci U S A (1988) 1.64
Reverse fibrin autography: a method to detect and partially characterize protease inhibitors after sodium dodecyl sulfate--polyacrylamide gel electrophoresis. Anal Biochem (1984) 1.59
Activation of rabbit Hageman factor by homogenates of cultured rabbit endothelial cells. J Clin Invest (1980) 1.53
Cellular localization of type 1 plasminogen activator inhibitor messenger RNA and protein in murine renal tissue. Am J Pathol (1993) 1.52
Changes in procoagulant and fibrinolytic gene expression during bleomycin-induced lung injury in the mouse. J Clin Invest (1995) 1.52
Detection and partial characterization of an inhibitor of plasminogen activator in human platelets. J Clin Invest (1984) 1.50
Type 1 plasminogen activator inhibitor. Prog Hemost Thromb (1989) 1.49
Immunologic relationship between platelet membrane glycoprotein GPIIb/IIIa and cell surface molecules expressed by a variety of cells. Proc Natl Acad Sci U S A (1986) 1.48
Murine CD14 gene expression in vivo: extramyeloid synthesis and regulation by lipopolysaccharide. J Exp Med (1995) 1.46
The primary plasminogen-activator inhibitors in endothelial cells, platelets, serum, and plasma are immunologically related. Proc Natl Acad Sci U S A (1985) 1.46
Murine tissue factor gene expression in vivo. Tissue and cell specificity and regulation by lipopolysaccharide. Am J Pathol (1993) 1.45
Tissue factor gene expression in the adipose tissues of obese mice. Proc Natl Acad Sci U S A (1998) 1.44
Leptin-dependent platelet aggregation and arterial thrombosis suggests a mechanism for atherothrombotic disease in obesity. J Clin Invest (2001) 1.41
Plasminogen activator inhibitor-1 and its cofactor vitronectin stabilize arterial thrombi after vascular injury in mice. Circulation (2001) 1.39
Structural and functional analysis of the plasminogen activator inhibitor-1 binding motif in the somatomedin B domain of vitronectin. J Biol Chem (1996) 1.31
Tissue distribution and regulation of murine von Willebrand factor gene expression in vivo. Blood (1998) 1.29
Fibrin deposition in tissues from endotoxin-treated mice correlates with decreases in the expression of urokinase-type but not tissue-type plasminogen activator. J Clin Invest (1996) 1.29
Distinct antithrombotic consequences of platelet glycoprotein Ibalpha and VI deficiency in a mouse model of arterial thrombosis. J Thromb Haemost (2006) 1.28
Activated protein C stimulates the fibrinolytic activity of cultured endothelial cells and decreases antiactivator activity. Proc Natl Acad Sci U S A (1985) 1.27
Human melanoma cells derived from lymphatic metastases use integrin alpha v beta 3 to adhere to lymph node vitronectin. J Clin Invest (1992) 1.26
The fibrinolytic system of the vascular wall. Clin Haematol (1985) 1.25
Tissue distribution of factor VIII gene expression in vivo--a closer look. Thromb Haemost (2001) 1.24
Plasminogen activator inhibitor-1 regulates cell adhesion by binding to the somatomedin B domain of vitronectin. J Cell Physiol (2001) 1.23
Tumor necrosis factor alpha is a key component in the obesity-linked elevation of plasminogen activator inhibitor 1. Proc Natl Acad Sci U S A (1999) 1.23
Comparative studies of the fibrinolytic activity of cultured vascular cells. Thromb Res (1979) 1.22
Evidence that type 1 plasminogen activator inhibitor binds to the somatomedin B domain of vitronectin. J Biol Chem (1991) 1.21
Thrombin stimulates tissue plasminogen activator release from cultured human endothelial cells. J Clin Invest (1984) 1.21
Coordinated induction of plasminogen activator inhibitor-1 (PAI-1) and inhibition of plasminogen activator gene expression by hypoxia promotes pulmonary vascular fibrin deposition. J Clin Invest (1998) 1.20
Extracellular matrix of cultured bovine aortic endothelial cells contains functionally active type 1 plasminogen activator inhibitor. Blood (1987) 1.20
Purification of a protein from bovine plasma that binds to type 1 plasminogen activator inhibitor and prevents its interaction with extracellular matrix. Evidence that the protein is vitronectin. J Biol Chem (1989) 1.20
Effect of thrombin on the fibrinolytic activity of cultured bovine endothelial cells. J Clin Invest (1979) 1.20
Tissue factor expression during human and mouse development. Am J Pathol (1996) 1.19
The somatomedin B domain of vitronectin. Structural requirements for the binding and stabilization of active type 1 plasminogen activator inhibitor. J Biol Chem (1994) 1.18
Gangliosides interact directly with plasminogen and urokinase and may mediate binding of these fibrinolytic components to cells. Biochemistry (1989) 1.15
Mechanism of protein C-dependent clot lysis: role of plasminogen activator inhibitor. Blood (1986) 1.15
Heat shock protein 27 kDa expression and phosphorylation regulates endothelial cell migration. FASEB J (1998) 1.14
Human endothelial cells produce IL-6. Lack of responses to exogenous IL-6. Ann N Y Acad Sci (1989) 1.12
Human endothelial cells synthesize protein S. Blood (1986) 1.12
Replication of dengue and junin viruses in cultured rabbit and human endothelial cells. Infect Immun (1978) 1.12
Gene expression during the development of Bacillus subtilis bacteriophage phi29. II. Resolution of viral-specific ribonucleic acid molecules. J Virol (1973) 1.12
Serum-mediated suppression of cell-associated plasminogen activator activity in cultured endothelial cells. Cell (1980) 1.11
Tissue distribution and regulation of plasminogen activator inhibitor-1 in obese mice. Mol Med (1996) 1.10
Immunoradiometric assay to measure the binding of a specific inhibitor to tissue-type plasminogen activator. J Lab Clin Med (1985) 1.09
Detection of vitronectin mRNA in tissues and cells of the mouse. Proc Natl Acad Sci U S A (1991) 1.09
Accelerated growth and senescence of arterial endothelial cells expressing the small molecular weight heat-shock protein HSP27. FASEB J (1995) 1.08
Kinetic analysis of the interactions between plasminogen activator inhibitor 1 and both urokinase and tissue plasminogen activator. Arch Biochem Biophys (1988) 1.08
Insulin continues to induce plasminogen activator inhibitor 1 gene expression in insulin-resistant mice and adipocytes. Mol Med (2000) 1.08
Effects of acidified fetal bovine serum on the fibrinolytic activity and growth of cells in culture. J Cell Physiol (1978) 1.06
Expression of type 1 plasminogen activator inhibitor in chronic pulmonary thromboemboli. Circulation (1994) 1.04
Astrocytes are the primary source of tissue factor in the murine central nervous system. A role for astrocytes in cerebral hemostasis. J Clin Invest (1993) 1.04
Inactivation of plasminogen activator inhibitor by oxidants. Biochemistry (1986) 1.04
SPARC induces the expression of type 1 plasminogen activator inhibitor in cultured bovine aortic endothelial cells. J Biol Chem (1991) 1.02
Binding of type 1 plasminogen activator inhibitor to the extracellular matrix of cultured bovine endothelial cells. J Biol Chem (1989) 1.01
An inhibitor of plasminogen activator in rabbit endothelial cells. J Biol Chem (1981) 1.01
Kinetic analysis of the interaction between type 1 plasminogen activator inhibitor and vitronectin and evidence that the bovine inhibitor binds to a thrombin-derived amino-terminal fragment of bovine vitronectin. Biochim Biophys Acta (1991) 1.00
Expression of fibrinolytic genes in atherosclerotic abdominal aortic aneurysm wall. A possible mechanism for aneurysm expansion. J Clin Invest (1995) 1.00
Quantitation and properties of the active and latent plasminogen activator inhibitors in cultures of human endothelial cells. Blood (1986) 1.00
Disruption of the plasminogen activator inhibitor 1 gene reduces the adiposity and improves the metabolic profile of genetically obese and diabetic ob/ob mice. FASEB J (2001) 0.99
Cultured granulosa cells produce two plasminogen activators and an antiactivator, each regulated differently by gonadotropins. Endocrinology (1985) 0.99
Induction of plasminogen activator inhibitor 1 gene expression in murine liver by lipopolysaccharide. Cellular localization and role of endogenous tumor necrosis factor-alpha. Am J Pathol (1997) 0.99
Fibrinolytic system of vascular endothelial cells. Role of plasminogen activator inhibitors. Haemostasis (1988) 0.99
The majority of type 1 plasminogen activator inhibitor associated with cultured human endothelial cells is located under the cells and is accessible to solution-phase tissue-type plasminogen activator. J Cell Biol (1990) 0.98
Characterization of two monoclonal antibodies against human tissue-type plasminogen activator. Thromb Haemost (1985) 0.96
Distribution of vitronectin mRNA during murine development. Dev Dyn (1995) 0.95
Endothelial cell synthesis of von Willebrand antigen II, von Willebrand factor, and von Willebrand factor/von Willebrand antigen II complex. J Clin Invest (1985) 0.94
Altered expression of plasminogen activator inhibitor type 1 in placentas from pregnant women with preeclampsia and/or intrauterine fetal growth retardation. Blood (1994) 0.94
Dysfunction of glomerular fibrinolysis in experimental antiglomerular basement membrane antibody glomerulonephritis. J Am Soc Nephrol (1993) 0.93
Basolateral membrane-associated 27-kDa heat shock protein and microfilament polymerization. J Biol Chem (1997) 0.93
Plasminogen receptors, urokinase receptors, and their modulation on human endothelial cells. Blood (1988) 0.93
Disruption of microtubules inhibits the stimulation of tissue plasminogen activator expression and promotes plasminogen activator inhibitor type 1 expression in human endothelial cells. Exp Cell Res (1992) 0.92
Messenger RNA for plasminogen activator inhibitor. Thromb Res (1986) 0.92
The dexamethasone-induced inhibitor of plasminogen activator in hepatoma cells is antigenically-related to an inhibitor produced by bovine aortic endothelial cells. Thromb Haemost (1986) 0.92
Binding of tissue plasminogen activator to human monocytes and monocytoid cells. Blood (1991) 0.92
Abnormal expression of type 1 plasminogen activator inhibitor and tissue factor in severe preeclampsia. Thromb Haemost (1998) 0.91
Role of tumor necrosis factor alpha in induction of murine CD14 gene expression by lipopolysaccharide. Infect Immun (1997) 0.91
Endotoxin stimulates expression of the murine urokinase receptor gene in vivo. Am J Pathol (1995) 0.91
Interactions between type 1 plasminogen activator inhibitor, extracellular matrix and vitronectin. Cell Differ Dev (1990) 0.91