Published in Genes Dev on May 01, 2005
Cross-species genomics matches driver mutations and cell compartments to model ependymoma. Nature (2010) 3.70
Notch promotes neural lineage entry by pluripotent embryonic stem cells. PLoS Biol (2006) 2.91
Molecular characterization of retinal stem cells and their niches in adult zebrafish. BMC Dev Biol (2006) 2.68
Interaction between Reelin and Notch signaling regulates neuronal migration in the cerebral cortex. Neuron (2008) 2.31
Fbw7 controls neural stem cell differentiation and progenitor apoptosis via Notch and c-Jun. Nat Neurosci (2010) 2.23
Fgf10 regulates transition period of cortical stem cell differentiation to radial glia controlling generation of neurons and basal progenitors. Neuron (2009) 2.09
Sustained Notch signaling in progenitors is required for sequential emergence of distinct cell lineages during organogenesis. Genes Dev (2006) 1.60
TGF-β1 promotes cerebral cortex radial glia-astrocyte differentiation in vivo. Front Cell Neurosci (2014) 1.51
Physiological Notch signaling promotes gliogenesis in the developing peripheral and central nervous systems. Development (2007) 1.47
Development and cancer of the cerebellum. Trends Neurosci (2011) 1.47
Cerebellum development and medulloblastoma. Curr Top Dev Biol (2011) 1.40
HIF-1α is critical for hypoxia-mediated maintenance of glioblastoma stem cells by activating Notch signaling pathway. Cell Death Differ (2011) 1.40
Molecular properties of CD133+ glioblastoma stem cells derived from treatment-refractory recurrent brain tumors. J Neurooncol (2009) 1.32
Notch: from neural development to neurological disorders. J Neurochem (2008) 1.31
Olfactory epithelium progenitors: insights from transgenic mice and in vitro biology. J Mol Histol (2007) 1.23
Is Pax6 critical for neurogenesis in the human fetal brain? Cereb Cortex (2007) 1.22
Genome-wide analysis of N1ICD/RBPJ targets in vivo reveals direct transcriptional regulation of Wnt, SHH, and hippo pathway effectors by Notch1. Stem Cells (2012) 1.20
Regional heterogeneity in astrocyte responses following contusive spinal cord injury in mice. J Comp Neurol (2010) 1.20
Don't fence me in: harnessing the beneficial roles of astrocytes for spinal cord repair. Restor Neurol Neurosci (2008) 1.19
Genetic lineage tracing defines distinct neurogenic and gliogenic stages of ventral telencephalic radial glial development. Neural Dev (2008) 1.11
Reinduction of ErbB2 in astrocytes promotes radial glial progenitor identity in adult cerebral cortex. Genes Dev (2007) 1.11
Sonic hedgehog and notch signaling can cooperate to regulate neurogenic divisions of neocortical progenitors. PLoS One (2011) 1.10
Nas transgenic mouse line allows visualization of Notch pathway activity in vivo. Genesis (2006) 1.03
Reelin induces a radial glial phenotype in human neural progenitor cells by activation of Notch-1. BMC Dev Biol (2008) 0.99
FGF signaling expands embryonic cortical surface area by regulating Notch-dependent neurogenesis. J Neurosci (2011) 0.98
Molecular diversity subdivides the adult forebrain neural stem cell population. Stem Cells (2014) 0.97
Notch2 is required for maintaining sustentacular cell function in the adult mouse main olfactory epithelium. Dev Biol (2007) 0.95
Fatty-acid binding proteins modulate sleep and enhance long-term memory consolidation in Drosophila. PLoS One (2011) 0.93
Brain fatty acid binding protein (Fabp7) is diurnally regulated in astrocytes and hippocampal granule cell precursors in adult rodent brain. PLoS One (2008) 0.92
Interactions between VEGFR and Notch signaling pathways in endothelial and neural cells. Cell Mol Life Sci (2013) 0.92
Dynamic signaling for neural stem cell fate determination. Cell Adh Migr (2009) 0.91
Fbxw7 regulates Notch to control specification of neural precursors for oligodendrocyte fate. Neural Dev (2012) 0.91
Expression profiling of autism candidate genes during human brain development implicates central immune signaling pathways. PLoS One (2011) 0.89
Botch promotes neurogenesis by antagonizing Notch. Dev Cell (2012) 0.89
Progenitors from the postnatal forebrain subventricular zone differentiate into cerebellar-like interneurons and cerebellar-specific astrocytes upon transplantation. Mol Cell Neurosci (2008) 0.87
ZFP423 coordinates Notch and bone morphogenetic protein signaling, selectively up-regulating Hes5 gene expression. J Biol Chem (2010) 0.86
The role of the transcription factor Rbpj in the development of dorsal root ganglia. Neural Dev (2011) 0.86
Molecular Diversity of Midbrain Development in Mouse, Human, and Stem Cells. Cell (2016) 0.85
The genesis of cerebellar GABAergic neurons: fate potential and specification mechanisms. Front Neuroanat (2012) 0.84
Adult spinal cord radial glia display a unique progenitor phenotype. PLoS One (2011) 0.84
Neocortical neurogenesis and neuronal migration. Wiley Interdiscip Rev Dev Biol (2012) 0.84
Neural reconnection in the transected spinal cord of the freshwater turtle Trachemys dorbignyi. J Comp Neurol (2009) 0.84
Aberrant fatty acid-binding protein-7 gene expression in cutaneous malignant melanoma. J Invest Dermatol (2010) 0.83
Activated Notch1 maintains the phenotype of radial glial cells and promotes their adhesion to laminin by upregulating nidogen. Glia (2008) 0.82
Prognostic molecular biomarkers for cutaneous malignant melanoma. J Surg Oncol (2011) 0.82
Neural crest and olfactory system: new prospective. Mol Neurobiol (2012) 0.82
Functional differentiation of a clone resembling embryonic cortical interneuron progenitors. Dev Neurobiol (2008) 0.82
A BAC transgenic mouse model to analyze the function of astroglial SPARCL1 (SC1) in the central nervous system. Glia (2008) 0.82
The multiple roles of fatty acid handling proteins in brain. Front Physiol (2012) 0.82
Populations of radial glial cells respond differently to reelin and neuregulin1 in a ferret model of cortical dysplasia. PLoS One (2010) 0.79
Neural stem/progenitor cells derived from the embryonic dorsal telencephalon of D6/GFP mice differentiate primarily into neurons after transplantation into a cortical lesion. Cell Mol Neurobiol (2009) 0.79
NF1 regulation of RAS/ERK signaling is required for appropriate granule neuron progenitor expansion and migration in cerebellar development. Genes Dev (2014) 0.79
Cortical Structure Alterations and Social Behavior Impairment in p50-Deficient Mice. Cereb Cortex (2016) 0.78
Notch signaling maintains neural rosette polarity. PLoS One (2013) 0.78
Interaction of brain fatty acid-binding protein with the polyunsaturated fatty acid environment as a potential determinant of poor prognosis in malignant glioma. Prog Lipid Res (2013) 0.78
Essential gene pathways for glioblastoma stem cells: clinical implications for prevention of tumor recurrence. Cancers (Basel) (2011) 0.78
MAZ mediates the cross-talk between CT-1 and NOTCH1 signaling during gliogenesis. Sci Rep (2016) 0.78
NOTCH1 and SOX10 are Essential for Proliferation and Radiation Resistance of Cancer Stem-Like Cells in Adenoid Cystic Carcinoma. Clin Cancer Res (2016) 0.77
Expression of aromatase in radial glial cells in the brain of the Japanese eel provides insight into the evolution of the cyp191a gene in Actinopterygians. PLoS One (2012) 0.77
The spatial and temporal arrangement of the radial glial scaffold suggests a role in axon tract formation in the developing spinal cord. J Anat (2012) 0.77
Fatty Acid binding protein 7 is a molecular marker in adenoid cystic carcinoma of the salivary glands: implications for clinical significance. Transl Oncol (2014) 0.77
Essential roles of leucine-rich glioma inactivated 1 in the development of embryonic and postnatal cerebellum. Sci Rep (2015) 0.76
Canonical Notch signaling plays an instructive role in auditory supporting cell development. Sci Rep (2016) 0.76
Derivation of Functional Human Astrocytes from Cerebral Organoids. Sci Rep (2017) 0.75
Discovering monotonic stemness marker genes from time-series stem cell microarray data. BMC Genomics (2015) 0.75
Loss of Usp9x disrupts cell adhesion, and components of the Wnt and Notch signaling pathways in neural progenitors. Sci Rep (2017) 0.75
Deficient T cell fate specification in mice with an induced inactivation of Notch1. Immunity (1999) 8.33
Neurons derived from radial glial cells establish radial units in neocortex. Nature (2001) 7.95
Autoradiographic study of cell migration during histogenesis of cerebral cortex in the mouse. Nature (1961) 6.36
Neuronal migration, with special reference to developing human brain: a review. Brain Res (1973) 4.49
Asymmetric inheritance of radial glial fibers by cortical neurons. Neuron (2001) 4.31
Isolation of radial glial cells by fluorescent-activated cell sorting reveals a neuronal lineage. Development (2000) 4.14
Targeting of cre to the Foxg1 (BF-1) locus mediates loxP recombination in the telencephalon and other developing head structures. Dev Biol (2000) 4.03
Radial glial identity is promoted by Notch1 signaling in the murine forebrain. Neuron (2000) 3.70
Radial glia serve as neuronal progenitors in all regions of the central nervous system. Neuron (2004) 3.58
Central nervous system neuronal migration. Annu Rev Neurosci (1999) 3.39
Recognition sequence of a highly conserved DNA binding protein RBP-J kappa. Nucleic Acids Res (1994) 3.36
Notch1 and notch2 have opposite effects on embryonal brain tumor growth. Cancer Res (2004) 2.90
Brain lipid-binding protein (BLBP): a novel signaling system in the developing mammalian CNS. Neuron (1994) 2.76
The role of notch in promoting glial and neural stem cell fates. Annu Rev Neurosci (2002) 2.65
Neuronal regulation of astroglial morphology and proliferation in vitro. J Cell Biol (1985) 2.60
Activated Notch2 signaling inhibits differentiation of cerebellar granule neuron precursors by maintaining proliferation. Neuron (2001) 2.32
Stimulation of in vitro transcription by the upstream element of the adenovirus-2 major late promoter involves a specific factor. Nucleic Acids Res (1984) 2.31
Continuing role for mouse Numb and Numbl in maintaining progenitor cells during cortical neurogenesis. Nat Neurosci (2004) 2.31
Keeping a good pathway down: transcriptional repression of Notch pathway target genes by CSL proteins. EMBO Rep (2002) 2.21
Neuregulin and erbB receptors play a critical role in neuronal migration. Neuron (1997) 1.99
The expression pattern of a novel gene encoding brain-fatty acid binding protein correlates with neuronal and glial cell development. Development (1994) 1.98
Fatty acid-binding proteins--insights from genetic manipulations. Prog Lipid Res (2004) 1.97
CNS gene encoding astrotactin, which supports neuronal migration along glial fibers. Science (1996) 1.96
Modulation of the notch signaling by Mash1 and Dlx1/2 regulates sequential specification and differentiation of progenitor cell types in the subcortical telencephalon. Development (2002) 1.95
Characterization of Notch3-deficient mice: normal embryonic development and absence of genetic interactions with a Notch1 mutation. Genesis (2003) 1.84
A notch-independent activity of suppressor of hairless is required for normal mechanoreceptor physiology. Cell (2000) 1.70
Role of GGF/neuregulin signaling in interactions between migrating neurons and radial glia in the developing cerebral cortex. Development (1997) 1.68
Neuregulin 1-erbB2 signaling is required for the establishment of radial glia and their transformation into astrocytes in cerebral cortex. Proc Natl Acad Sci U S A (2003) 1.55
Radial glia is a progenitor of neocortical neurons in the developing cerebral cortex. Neurosci Res (2001) 1.49
Fibroblast growth factor receptor signaling promotes radial glial identity and interacts with Notch1 signaling in telencephalic progenitors. J Neurosci (2004) 1.48
Reelin signaling directly affects radial glia morphology and biochemical maturation. Development (2003) 1.44
POU transcription factors control expression of CNS stem cell-specific genes. Development (1998) 1.28
Sequential signaling through Notch1 and erbB receptors mediates radial glia differentiation. J Neurosci (2003) 1.21
Expression patterns of Notch1, Notch2, and Notch3 suggest multiple functional roles for the Notch-DSL signaling system during brain development. J Comp Neurol (2001) 1.18
Differentiating neurons activate transcription of the brain lipid-binding protein gene in radial glia through a novel regulatory element. Development (1995) 1.09
Brain lipid binding protein in axon-Schwann cell interactions and peripheral nerve tumorigenesis. Mol Cell Biol (2003) 0.97
Context-dependent utilization of Notch activity in Drosophila glial determination. Development (2002) 0.91
The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain. Science (2009) 18.82
A gene expression atlas of the central nervous system based on bacterial artificial chromosomes. Nature (2003) 16.48
Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor. Proc Natl Acad Sci U S A (2003) 15.59
A translational profiling approach for the molecular characterization of CNS cell types. Cell (2008) 8.69
Petilla terminology: nomenclature of features of GABAergic interneurons of the cerebral cortex. Nat Rev Neurosci (2008) 8.14
The knockout mouse project. Nat Genet (2004) 7.80
Application of a translational profiling approach for the comparative analysis of CNS cell types. Cell (2008) 7.74
A resource of Cre driver lines for genetic targeting of GABAergic neurons in cerebral cortex. Neuron (2011) 6.93
Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex. Nat Cell Biol (2009) 6.69
Targeting Cre recombinase to specific neuron populations with bacterial artificial chromosome constructs. J Neurosci (2007) 5.87
Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes. Nature (2010) 5.11
Medulloblastoma can be initiated by deletion of Patched in lineage-restricted progenitors or stem cells. Cancer Cell (2008) 5.06
The temporal and spatial origins of cortical interneurons predict their physiological subtype. Neuron (2005) 4.90
MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system. Cell (2012) 4.56
A novel protein complex linking the delta 2 glutamate receptor and autophagy: implications for neurodegeneration in lurcher mice. Neuron (2002) 4.27
Division-coupled astrocytic differentiation and age-related depletion of neural stem cells in the adult hippocampus. Cell Stem Cell (2011) 4.08
Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants. Genes Dev (2004) 3.95
Sonic hedgehog is required for progenitor cell maintenance in telencephalic stem cell niches. Neuron (2003) 3.76
Highly efficient modification of bacterial artificial chromosomes (BACs) using novel shuttle vectors containing the R6Kgamma origin of replication. Genome Res (2002) 3.61
Genetic fate mapping reveals that the caudal ganglionic eminence produces a large and diverse population of superficial cortical interneurons. J Neurosci (2010) 3.61
Radial glia serve as neuronal progenitors in all regions of the central nervous system. Neuron (2004) 3.58
Induction of autophagy in axonal dystrophy and degeneration. J Neurosci (2006) 3.28
Autophagy and its possible roles in nervous system diseases, damage and repair. Autophagy (2005) 3.27
Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch. Immunity (2007) 3.19
Math1 is expressed in temporally discrete pools of cerebellar rhombic-lip neural progenitors. Neuron (2005) 3.17
Foxg1 suppresses early cortical cell fate. Science (2004) 3.15
Notch3 is required for arterial identity and maturation of vascular smooth muscle cells. Genes Dev (2004) 3.00
A disinhibitory circuit mediates motor integration in the somatosensory cortex. Nat Neurosci (2013) 2.97
Developmental transcription factor slug is required for effective re-epithelialization by adult keratinocytes. J Cell Physiol (2005) 2.91
A mouse model of Alagille syndrome: Notch2 as a genetic modifier of Jag1 haploinsufficiency. Development (2002) 2.88
The functional organization of cutaneous low-threshold mechanosensory neurons. Cell (2011) 2.83
IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress. Cell Metab (2012) 2.80
Physiologically distinct temporal cohorts of cortical interneurons arise from telencephalic Olig2-expressing precursors. J Neurosci (2007) 2.80
In vivo activation of midbrain dopamine neurons via sensitized, high-affinity alpha 6 nicotinic acetylcholine receptors. Neuron (2008) 2.69
The caudal ganglionic eminence is a source of distinct cortical and subcortical cell populations. Nat Neurosci (2002) 2.69
gamma-secretase functions through Notch signaling to maintain skin appendages but is not required for their patterning or initial morphogenesis. Dev Cell (2004) 2.68
The role of notch in promoting glial and neural stem cell fates. Annu Rev Neurosci (2002) 2.65
New insights into the classification and nomenclature of cortical GABAergic interneurons. Nat Rev Neurosci (2013) 2.65
Jagged1 is the pathological link between Wnt and Notch pathways in colorectal cancer. Proc Natl Acad Sci U S A (2009) 2.63
Dysfunction of axonemal dynein heavy chain Mdnah5 inhibits ependymal flow and reveals a novel mechanism for hydrocephalus formation. Hum Mol Genet (2004) 2.63
Characterization of Nkx6-2-derived neocortical interneuron lineages. Cereb Cortex (2009) 2.61
Mosaic removal of hedgehog signaling in the adult SVZ reveals that the residual wild-type stem cells have a limited capacity for self-renewal. J Neurosci (2007) 2.56
The Notch ligand JAG1 is required for sensory progenitor development in the mammalian inner ear. PLoS Genet (2006) 2.56
The distinct temporal origins of olfactory bulb interneuron subtypes. J Neurosci (2008) 2.54
The largest group of superficial neocortical GABAergic interneurons expresses ionotropic serotonin receptors. J Neurosci (2010) 2.50
Morphogen to mitogen: the multiple roles of hedgehog signalling in vertebrate neural development. Nat Rev Neurosci (2006) 2.42
The genetics of early telencephalon patterning: some assembly required. Nat Rev Neurosci (2008) 2.40
The Notch ligands DLL1 and JAG2 act synergistically to regulate hair cell development in the mammalian inner ear. Development (2005) 2.36
The requirement of Nkx2-1 in the temporal specification of cortical interneuron subtypes. Neuron (2008) 2.33
Interaction between Reelin and Notch signaling regulates neuronal migration in the cerebral cortex. Neuron (2008) 2.31
Neuronal activity is required for the development of specific cortical interneuron subtypes. Nature (2011) 2.28
Pathological cell-cell interactions elicited by a neuropathogenic form of mutant Huntingtin contribute to cortical pathogenesis in HD mice. Neuron (2005) 2.11
To beat or not to beat: roles of cilia in development and disease. Hum Mol Genet (2003) 2.11
Lynx1, a cholinergic brake, limits plasticity in adult visual cortex. Science (2010) 2.11
Minimal aberrant behavioral phenotypes of neuroligin-3 R451C knockin mice. Autism Res (2008) 2.08
A requirement for Notch1 distinguishes 2 phases of definitive hematopoiesis during development. Blood (2004) 2.06
Genetic address book for retinal cell types. Nat Neurosci (2009) 2.02
The developmental integration of cortical interneurons into a functional network. Curr Top Dev Biol (2009) 2.01
Critical role of endothelial Notch1 signaling in postnatal angiogenesis. Circ Res (2006) 1.91
Notch 1 inhibits photoreceptor production in the developing mammalian retina. Development (2006) 1.91
Characterization of Notch3-deficient mice: normal embryonic development and absence of genetic interactions with a Notch1 mutation. Genesis (2003) 1.84
Bile duct proliferation in liver-specific Jag1 conditional knockout mice: effects of gene dosage. Hepatology (2007) 1.78
Hedgehog signaling in the subventricular zone is required for both the maintenance of stem cells and the migration of newborn neurons. J Neurosci (2007) 1.78
Notch signaling regulates left-right asymmetry determination by inducing Nodal expression. Genes Dev (2003) 1.76
Impaired embryonic haematopoiesis yet normal arterial development in the absence of the Notch ligand Jagged1. EMBO J (2008) 1.71
Loss of function of axonemal dynein Mdnah5 causes primary ciliary dyskinesia and hydrocephalus. Hum Mol Genet (2002) 1.69
Repression of PTEN phosphatase by Snail1 transcriptional factor during gamma radiation-induced apoptosis. Mol Cell Biol (2008) 1.68
Directed migration of cortical interneurons depends on the cell-autonomous action of Sip1. Neuron (2013) 1.67
The cell-intrinsic requirement of Sox6 for cortical interneuron development. Neuron (2009) 1.66
Loss of notch activity in the developing central nervous system leads to increased cell death. Dev Neurosci (2006) 1.65
Cell type-specific regulation of DARPP-32 phosphorylation by psychostimulant and antipsychotic drugs. Nat Neurosci (2008) 1.63
Dorsoventral patterning is established in the telencephalon of mutants lacking both Gli3 and Hedgehog signaling. Development (2002) 1.61
Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL. Blood (2010) 1.60
Notch signaling regulates bile duct morphogenesis in mice. PLoS One (2008) 1.59
Genetic approaches identify adult pituitary stem cells. Proc Natl Acad Sci U S A (2008) 1.58
Smooth muscle Notch1 mediates neointimal formation after vascular injury. Circulation (2009) 1.58
Snail family genes are required for left-right asymmetry determination, but not neural crest formation, in mice. Proc Natl Acad Sci U S A (2006) 1.58
Parsing the prosencephalon. Nat Rev Neurosci (2002) 1.57
Novel modulation of neuronal nicotinic acetylcholine receptors by association with the endogenous prototoxin lynx1. Neuron (2002) 1.56
Generation of new Notch2 mutant alleles. Genesis (2006) 1.56
Oxytocin enhances hippocampal spike transmission by modulating fast-spiking interneurons. Nature (2013) 1.54
Gene expression in cortical interneuron precursors is prescient of their mature function. Cereb Cortex (2008) 1.51
Cell-type specific properties of pyramidal neurons in neocortex underlying a layout that is modifiable depending on the cortical area. Cereb Cortex (2009) 1.51
Slug is a novel downstream target of MyoD. Temporal profiling in muscle regeneration. J Biol Chem (2002) 1.50
Fibroblast growth factor receptor signaling promotes radial glial identity and interacts with Notch1 signaling in telencephalic progenitors. J Neurosci (2004) 1.48
Distinct roles of PDE4 and PDE10A in the regulation of cAMP/PKA signaling in the striatum. J Neurosci (2008) 1.48
The prototoxin lynx1 acts on nicotinic acetylcholine receptors to balance neuronal activity and survival in vivo. Neuron (2006) 1.46
Multiple functions of Snail family genes during palate development in mice. Development (2007) 1.45
Identification of the cortical neurons that mediate antidepressant responses. Cell (2012) 1.42
Analytical approaches to RNA profiling data for the identification of genes enriched in specific cells. Nucleic Acids Res (2010) 1.41
Tethering naturally occurring peptide toxins for cell-autonomous modulation of ion channels and receptors in vivo. Neuron (2004) 1.39
Common origins of hippocampal Ivy and nitric oxide synthase expressing neurogliaform cells. J Neurosci (2010) 1.39
Jag2-Notch1 signaling regulates oral epithelial differentiation and palate development. Dev Dyn (2006) 1.37
Cholinergic interneurons in the nucleus accumbens regulate depression-like behavior. Proc Natl Acad Sci U S A (2012) 1.33
Rapid bacterial artificial chromosome modification for large-scale mouse transgenesis. Nat Protoc (2010) 1.33
GABAergic interneuron lineages selectively sort into specific cortical layers during early postnatal development. Cereb Cortex (2010) 1.31
Notch2 governs the rate of generation of mouse long- and short-term repopulating stem cells. J Clin Invest (2011) 1.29
Temporal requirement for hedgehog signaling in ventral telencephalic patterning. Development (2004) 1.28