IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress.

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Published in Cell Metab on August 08, 2012

Authors

Alana G Lerner1, John-Paul Upton, P V K Praveen, Rajarshi Ghosh, Yoshimi Nakagawa, Aeid Igbaria, Sarah Shen, Vinh Nguyen, Bradley J Backes, Myriam Heiman, Nathaniel Heintz, Paul Greengard, Simon Hui, Qizhi Tang, Ala Trusina, Scott A Oakes, Feroz R Papa

Author Affiliations

1: Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.

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