Published in J Biol Chem on November 03, 2003
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MicroRNA-298 and microRNA-328 regulate expression of mouse beta-amyloid precursor protein-converting enzyme 1. J Biol Chem (2008) 1.86
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MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res (2005) 18.58
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A microRNA array reveals extensive regulation of microRNAs during brain development. RNA (2003) 9.76
MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells. Cell (2009) 8.14
Identification of many microRNAs that copurify with polyribosomes in mammalian neurons. Proc Natl Acad Sci U S A (2003) 7.95
HDAC2 negatively regulates memory formation and synaptic plasticity. Nature (2009) 6.96
Recovery of learning and memory is associated with chromatin remodelling. Nature (2007) 6.72
Specific microRNAs modulate embryonic stem cell-derived neurogenesis. Stem Cells (2005) 6.72
Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling. Cell (2009) 5.34
MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators. Mol Cell Biol (2008) 5.21
The Amphimedon queenslandica genome and the evolution of animal complexity. Nature (2010) 5.11
MicroRNA profiling of the murine hematopoietic system. Genome Biol (2005) 4.94
SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis. EMBO J (2007) 4.66
A novel pathway regulates memory and plasticity via SIRT1 and miR-134. Nature (2010) 4.39
MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-α-PU.1 pathway. Nat Med (2010) 4.24
Trekking across the brain: the journey of neuronal migration. Cell (2007) 3.90
Targeted optogenetic stimulation and recording of neurons in vivo using cell-type-specific expression of Channelrhodopsin-2. Nat Protoc (2010) 3.71
MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells. Cancer Res (2008) 3.70
Brain imaging and fluid biomarker analysis in young adults at genetic risk for autosomal dominant Alzheimer's disease in the presenilin 1 E280A kindred: a case-control study. Lancet Neurol (2012) 3.48
Ndel1 operates in a common pathway with LIS1 and cytoplasmic dynein to regulate cortical neuronal positioning. Neuron (2004) 3.33
Aberrant Cdk5 activation by p25 triggers pathological events leading to neurodegeneration and neurofibrillary tangles. Neuron (2003) 2.97
MicroRNA-21 knockdown disrupts glioma growth in vivo and displays synergistic cytotoxicity with neural precursor cell delivered S-TRAIL in human gliomas. Cancer Res (2007) 2.90
Deregulation of HDAC1 by p25/Cdk5 in neurotoxicity. Neuron (2008) 2.88
Alzheimer's Prevention Initiative: a plan to accelerate the evaluation of presymptomatic treatments. J Alzheimers Dis (2011) 2.78
Apolipoprotein Eepsilon4 modifies Alzheimer's disease onset in an E280A PS1 kindred. Ann Neurol (2003) 2.72
Opposing roles of transient and prolonged expression of p25 in synaptic plasticity and hippocampus-dependent memory. Neuron (2005) 2.68
Modulating inflammatory monocytes with a unique microRNA gene signature ameliorates murine ALS. J Clin Invest (2012) 2.67
An epigenetic blockade of cognitive functions in the neurodegenerating brain. Nature (2012) 2.67
Florbetapir PET analysis of amyloid-β deposition in the presenilin 1 E280A autosomal dominant Alzheimer's disease kindred: a cross-sectional study. Lancet Neurol (2012) 2.65
G protein betagamma subunits and AGS3 control spindle orientation and asymmetric cell fate of cerebral cortical progenitors. Cell (2005) 2.64
Identification and rescue of α-synuclein toxicity in Parkinson patient-derived neurons. Science (2013) 2.61
miR-296 regulates growth factor receptor overexpression in angiogenic endothelial cells. Cancer Cell (2008) 2.57
Negative regulation of Vps34 by Cdk mediated phosphorylation. Mol Cell (2010) 2.57
Cep120 and TACCs control interkinetic nuclear migration and the neural progenitor pool. Neuron (2007) 2.53
Heterogeneous dysregulation of microRNAs across the autism spectrum. Neurogenetics (2008) 2.50
Life is a journey: a genetic look at neocortical development. Nat Rev Genet (2002) 2.46
CHIP-Hsc70 complex ubiquitinates phosphorylated tau and enhances cell survival. J Biol Chem (2003) 2.27
14-3-3epsilon is important for neuronal migration by binding to NUDEL: a molecular explanation for Miller-Dieker syndrome. Nat Genet (2003) 2.27
MicroRNAs potentiate neural development. Neuron (2009) 2.25
APP processing is regulated by cytoplasmic phosphorylation. J Cell Biol (2003) 2.21
The Elegance of the MicroRNAs: A Neuronal Perspective. Neuron (2005) 2.12
Dixdc1 is a critical regulator of DISC1 and embryonic cortical development. Neuron (2010) 2.08
Cyclin-dependent kinases in brain development and disease. Annu Rev Cell Dev Biol (2011) 2.08
Downregulated microRNA-200a in meningiomas promotes tumor growth by reducing E-cadherin and activating the Wnt/beta-catenin signaling pathway. Mol Cell Biol (2009) 2.06
A NUDEL-dependent mechanism of neurofilament assembly regulates the integrity of CNS neurons. Nat Cell Biol (2004) 2.06
MicroRNAs in cerebrospinal fluid identify glioblastoma and metastatic brain cancers and reflect disease activity. Neuro Oncol (2012) 2.02
Somatodendritic microRNAs identified by laser capture and multiplex RT-PCR. RNA (2007) 2.01
Human glioma growth is controlled by microRNA-10b. Cancer Res (2011) 1.96
A post-synaptic scaffold at the origin of the animal kingdom. PLoS One (2007) 1.96
A coordinated local translational control point at the synapse involving relief from silencing and MOV10 degradation. Neuron (2009) 1.96
Functional integration of dopaminergic neurons directly converted from mouse fibroblasts. Cell Stem Cell (2011) 1.95
Targeting the correct HDAC(s) to treat cognitive disorders. Trends Pharmacol Sci (2010) 1.94
Amyloid-independent mechanisms in Alzheimer's disease pathogenesis. J Neurosci (2010) 1.93
Gene expression profiling of substantia nigra dopamine neurons: further insights into Parkinson's disease pathology. Brain (2008) 1.92
miR-101 is down-regulated in glioblastoma resulting in EZH2-induced proliferation, migration, and angiogenesis. Oncotarget (2010) 1.92
Guiding neuronal cell migrations. Cold Spring Harb Perspect Biol (2010) 1.82
Cyclin-dependent kinase 5 phosphorylates the N-terminal domain of the postsynaptic density protein PSD-95 in neurons. J Neurosci (2004) 1.81
Deletion of the neuron-specific protein delta-catenin leads to severe cognitive and synaptic dysfunction. Curr Biol (2004) 1.80
Cyclin-dependent kinases: a family portrait. Nat Cell Biol (2009) 1.80
p25/cyclin-dependent kinase 5 induces production and intraneuronal accumulation of amyloid beta in vivo. J Neurosci (2006) 1.80
Autism spectrum disorder susceptibility gene TAOK2 affects basal dendrite formation in the neocortex. Nat Neurosci (2012) 1.79
Reactive glia in the injured brain acquire stem cell properties in response to sonic hedgehog. [corrected]. Cell Stem Cell (2013) 1.77
Histone acetylation: molecular mnemonics on the chromatin. Nat Rev Neurosci (2013) 1.77
Cdk5 deregulation in the pathogenesis of Alzheimer's disease. Trends Mol Med (2004) 1.76
Synaptic tagging -- who's it? Nat Rev Neurosci (2002) 1.75
Doublecortin-like kinase controls neurogenesis by regulating mitotic spindles and M phase progression. Neuron (2006) 1.74
Common DISC1 polymorphisms disrupt Wnt/GSK3β signaling and brain development. Neuron (2011) 1.67
Epigenetic regulation of gene expression in physiological and pathological brain processes. Physiol Rev (2011) 1.66
MicroRNA regulation of neural stem cells and neurogenesis. J Neurosci (2010) 1.64
Cdk5rap2 interacts with pericentrin to maintain the neural progenitor pool in the developing neocortex. Neuron (2010) 1.60
A Jekyll and Hyde kinase: roles for Cdk5 in brain development and disease. Curr Opin Neurobiol (2004) 1.60
The Erbin PDZ domain binds with high affinity and specificity to the carboxyl termini of delta-catenin and ARVCF. J Biol Chem (2002) 1.59
Par-4 links dopamine signaling and depression. Cell (2005) 1.58
miRNA-7 attenuation in Schwannoma tumors stimulates growth by upregulating three oncogenic signaling pathways. Cancer Res (2010) 1.54
Parkin localizes to the Lewy bodies of Parkinson disease and dementia with Lewy bodies. Am J Pathol (2002) 1.54
Variants in triggering receptor expressed on myeloid cells 2 are associated with both behavioral variant frontotemporal lobar degeneration and Alzheimer's disease. Neurobiol Aging (2013) 1.53
The potential of HDAC inhibitors as cognitive enhancers. Annu Rev Pharmacol Toxicol (2013) 1.52
Coupling PAF signaling to dynein regulation: structure of LIS1 in complex with PAF-acetylhydrolase. Neuron (2004) 1.51
Neural sirtuin 6 (Sirt6) ablation attenuates somatic growth and causes obesity. Proc Natl Acad Sci U S A (2010) 1.49
MicroRNA profiling reveals two distinct p53-related human pluripotent stem cell states. Cell Stem Cell (2010) 1.49
RNAi functions in cultured mammalian neurons. Proc Natl Acad Sci U S A (2002) 1.42
Binding of tau to heat shock protein 27 leads to decreased concentration of hyperphosphorylated tau and enhanced cell survival. J Biol Chem (2004) 1.42
Detection of a microRNA signal in an in vivo expression set of mRNAs. PLoS One (2007) 1.40
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Identification of piRNAs in the central nervous system. RNA (2011) 1.39
The cochaperone BAG2 sweeps paired helical filament- insoluble tau from the microtubule. J Neurosci (2009) 1.38
Dual regulation of neuronal morphogenesis by a delta-catenin-cortactin complex and Rho. J Cell Biol (2003) 1.35
A hippocampal Cdk5 pathway regulates extinction of contextual fear. Nat Neurosci (2007) 1.35
Highly conserved O-fucose sites have distinct effects on Notch1 function. J Biol Chem (2005) 1.35
Pyramidal neuron polarity axis is defined at the bipolar stage. J Cell Sci (2008) 1.31
Interaction of FUS and HDAC1 regulates DNA damage response and repair in neurons. Nat Neurosci (2013) 1.31
Cdk5: one of the links between senile plaques and neurofibrillary tangles? J Alzheimers Dis (2003) 1.30
The cyclin-dependent kinase 5 activators p35 and p39 interact with the alpha-subunit of Ca2+/calmodulin-dependent protein kinase II and alpha-actinin-1 in a calcium-dependent manner. J Neurosci (2002) 1.30
Cdk5 promotes synaptogenesis by regulating the subcellular distribution of the MAGUK family member CASK. Neuron (2007) 1.30
The role of Cdk5 in neuroendocrine thyroid cancer. Cancer Cell (2013) 1.30
SIRT1 collaborates with ATM and HDAC1 to maintain genomic stability in neurons. Nat Neurosci (2013) 1.30