Published in Methods Enzymol on January 01, 2003
The Polycomb group protein EZH2 directly controls DNA methylation. Nature (2005) 13.67
Functional diversity of protein phosphatase-1, a cellular economizer and reset button. Physiol Rev (2004) 3.82
Docking motif-guided mapping of the interactome of protein phosphatase-1. Chem Biol (2009) 2.17
NPP-type ectophosphodiesterases: unity in diversity. Trends Biochem Sci (2005) 2.08
False-positive detection of recombinant human erythropoietin in urine following strenuous physical exercise. Blood (2006) 2.06
Structural basis of substrate discrimination and integrin binding by autotaxin. Nat Struct Mol Biol (2011) 1.81
Degeneracy and function of the ubiquitous RVXF motif that mediates binding to protein phosphatase-1. J Biol Chem (2003) 1.72
PP1/Repo-man dephosphorylates mitotic histone H3 at T3 and regulates chromosomal aurora B targeting. Curr Biol (2011) 1.63
Inhibition of spliceosome assembly by the cell cycle-regulated protein kinase MELK and involvement of splicing factor NIPP1. J Biol Chem (2003) 1.46
Protein phosphatase 1 regulates the histone code for long-term memory. J Neurosci (2009) 1.44
Substrate specificity and activity regulation of protein kinase MELK. J Biol Chem (2005) 1.43
Testing for recombinant erythropoietin. Am J Hematol (2008) 1.39
The PP1 binding code: a molecular-lego strategy that governs specificity. FEBS J (2012) 1.38
The hydrolysis of lysophospholipids and nucleotides by autotaxin (NPP2) involves a single catalytic site. FEBS Lett (2003) 1.38
Protein phosphatase 1 binds to the RNA recognition motif of several splicing factors and regulates alternative pre-mRNA processing. Hum Mol Genet (2007) 1.33
Proteolytic maturation and activation of autotaxin (NPP2), a secreted metastasis-enhancing lysophospholipase D. J Cell Sci (2005) 1.28
Interactor-mediated nuclear translocation and retention of protein phosphatase-1. J Biol Chem (2004) 1.25
Regulator-driven functional diversification of protein phosphatase-1 in eukaryotic evolution. Bioessays (2002) 1.22
Protein phosphatase-1 dephosphorylates the C-terminal domain of RNA polymerase-II. J Biol Chem (2002) 1.14
Nuclear protein phosphatase-1 regulates HIV-1 transcription. J Biol Chem (2003) 1.12
Cancer cell expression of autotaxin controls bone metastasis formation in mouse through lysophosphatidic acid-dependent activation of osteoclasts. PLoS One (2010) 1.12
Binding of the concave surface of the Sds22 superhelix to the alpha 4/alpha 5/alpha 6-triangle of protein phosphatase-1. J Biol Chem (2002) 1.11
Nuclear targeting of protein phosphatase-1 by HIV-1 Tat protein. J Biol Chem (2005) 1.10
Y65C missense mutation in the WW domain of the Golabi-Ito-Hall syndrome protein PQBP1 affects its binding activity and deregulates pre-mRNA splicing. J Biol Chem (2010) 1.09
Substrate-specifying determinants of the nucleotide pyrophosphatases/phosphodiesterases NPP1 and NPP2. Biochem J (2004) 1.08
Modulation of purinergic signaling by NPP-type ectophosphodiesterases. Purinergic Signal (2006) 1.07
Glucose activates a protein phosphatase-1-mediated signaling pathway to enhance overall translation in pancreatic beta-cells. Endocrinology (2006) 1.07
Spindle checkpoint silencing: PP1 tips the balance. Curr Biol (2011) 1.07
Structure and function of the two tandem WW domains of the pre-mRNA splicing factor FBP21 (formin-binding protein 21). J Biol Chem (2009) 1.07
Protein phosphatase-1 activates CDK9 by dephosphorylating Ser175. PLoS One (2011) 1.06
Protein phosphatase-1 is a novel regulator of the interaction between IRBIT and the inositol 1,4,5-trisphosphate receptor. Biochem J (2007) 1.05
Retracted Maternal embryonic leucine zipper kinase (MELK) reduces replication stress in glioblastoma cells. J Biol Chem (2013) 1.04
A complex of catalytically inactive protein phosphatase-1 sandwiched between Sds22 and inhibitor-3. Biochemistry (2007) 1.04
An essential oligomannosidic glycan chain in the catalytic domain of autotaxin, a secreted lysophospholipase-D. J Biol Chem (2007) 1.04
Phosphorylation-dependent interaction between the splicing factors SAP155 and NIPP1. J Biol Chem (2002) 1.03
Aurora B defines its own chromosomal targeting by opposing the recruitment of the phosphatase scaffold Repo-Man. Curr Biol (2013) 1.02
Expression of a protein phosphatase 1 inhibitor, cdNIPP1, increases CDK9 threonine 186 phosphorylation and inhibits HIV-1 transcription. J Biol Chem (2010) 1.02
A novel glycogen-targeting subunit of protein phosphatase 1 that is regulated by insulin and shows differential tissue distribution in humans and rodents. FEBS J (2005) 1.01
Rapid clearance of the circulating metastatic factor autotaxin by the scavenger receptors of liver sinusoidal endothelial cells. Cancer Lett (2009) 1.00
PNUTS enhances in vitro chromosome decondensation in a PP1-dependent manner. Biochem J (2005) 0.96
SIPP1, a novel pre-mRNA splicing factor and interactor of protein phosphatase-1. Biochem J (2004) 0.95
Functional characterization of the non-catalytic ectodomains of the nucleotide pyrophosphatase/phosphodiesterase NPP1. Biochem J (2003) 0.95
CDK2 regulates HIV-1 transcription by phosphorylation of CDK9 on serine 90. Retrovirology (2012) 0.95
4D-networking by mitotic phosphatases. Curr Opin Cell Biol (2013) 0.95
Identification of protein phosphatase 1 as a regulator of the LRRK2 phosphorylation cycle. Biochem J (2013) 0.94
YPI1 and SDS22 proteins regulate the nuclear localization and function of yeast type 1 phosphatase Glc7. J Biol Chem (2006) 0.94
The molecular basis for substrate specificity of the nuclear NIPP1:PP1 holoenzyme. Structure (2012) 0.94
Domain interplay mediated by an essential disulfide linkage is critical for the activity and secretion of the metastasis-promoting enzyme autotaxin. J Biol Chem (2009) 0.93
Sperm PP1gamma2 is regulated by a homologue of the yeast protein phosphatase binding protein sds22. Biol Reprod (2002) 0.93
Challenges and opportunities in the development of protein phosphatase-directed therapeutics. ACS Chem Biol (2012) 0.91
The protein phosphatase-1 regulator NIPP1 is also a splicing factor involved in a late step of spliceosome assembly. J Biol Chem (2002) 0.90
The phosphatase interactor NIPP1 regulates the occupancy of the histone methyltransferase EZH2 at Polycomb targets. Nucleic Acids Res (2010) 0.89
Synthesis and characterization of pseudocantharidins, novel phosphatase modulators that promote the inclusion of exon 7 into the SMN (survival of motoneuron) pre-mRNA. J Biol Chem (2011) 0.89
The KH-Tudor domain of a-kinase anchoring protein 149 mediates RNA-dependent self-association. Biochemistry (2006) 0.88
C6 pyridinium ceramide influences alternative pre-mRNA splicing by inhibiting protein phosphatase-1. Nucleic Acids Res (2011) 0.88
Nucleocytoplasmic shuttling of the splicing factor SIPP1. J Biol Chem (2005) 0.87
Structure of NPP1, an ectonucleotide pyrophosphatase/phosphodiesterase involved in tissue calcification. Structure (2012) 0.87
The guanine-nucleotide-exchange factor P-Rex1 is activated by protein phosphatase 1α. Biochem J (2012) 0.87
The nuclear scaffold protein NIPP1 is essential for early embryonic development and cell proliferation. Mol Cell Biol (2004) 0.87
Characterization of the condensin component Cnap1 and protein kinase Melk as novel E2F target genes down-regulated by 1,25-dihydroxyvitamin D3. J Biol Chem (2005) 0.86
The protein phosphatase-1 (PP1) regulator, nuclear inhibitor of PP1 (NIPP1), interacts with the polycomb group protein, embryonic ectoderm development (EED), and functions as a transcriptional repressor. J Biol Chem (2003) 0.86
AKAP149 is a novel PP1 specifier required to maintain nuclear envelope integrity in G1 phase. J Cell Sci (2003) 0.86
Regulation of protein phosphatase 1gamma activity in hypoxia through increased interaction with NIPP1: implications for cellular metabolism. J Cell Physiol (2006) 0.85
Growth inhibition properties of the putative prostate cancer biomarkers PSP94 and CRISP-3. Asian J Androl (2010) 0.85
A role for PP1/NIPP1 in steering migration of human cancer cells. PLoS One (2012) 0.84
Glucose-dependent regulation of AMP-activated protein kinase in MIN6 beta cells is not affected by the protein kinase A pathway. FEBS Lett (2012) 0.84
Methylation of PITX2, HOXD3, RASSF1 and TDRD1 predicts biochemical recurrence in high-risk prostate cancer. J Cancer Res Clin Oncol (2014) 0.84
NIPP1 maintains EZH2 phosphorylation and promoter occupancy at proliferation-related target genes. Nucleic Acids Res (2012) 0.83
The translation initiation factor eIF2beta is an interactor of protein phosphatase-1. Biochem J (2006) 0.82
Development of a peptide that selectively activates protein phosphatase-1 in living cells. Angew Chem Int Ed Engl (2012) 0.82
Determinants of the nucleolar targeting of protein phosphatase-1. FEBS Lett (2005) 0.82
The transcriptional repression by NIPP1 is mediated by Polycomb group proteins. Biochim Biophys Acta (2007) 0.79
Interactor-guided dephosphorylation by protein phosphatase-1. Methods Mol Biol (2013) 0.78
Nature of the nuclear inclusions formed by PQBP1, a protein linked to neurodegenerative polyglutamine diseases. Eur J Cell Biol (2008) 0.78
Chemical activators of protein phosphatase-1 induce calcium release inside intact cells. Chem Biol (2013) 0.78
Approaches to defining the ancestral eukaryotic protein complexome. Bioessays (2006) 0.77
Endogenous regulators of protein phosphatase-1 during mouse oocyte development and meiosis. Reproduction (2004) 0.77
A tighter RVxF motif makes a finer Sift. Chem Biol (2006) 0.76
Maternal embryonic leucine zipper kinase (MELK) reduces replication stress in glioblastoma cells. J Biol Chem (2017) 0.75
Correction: Biogenesis and activity regulation of protein phosphatase 1. Biochem Soc Trans (2017) 0.75