Published in Science on March 26, 2004
Changing scientific publishing. Science (2004) 0.75
Cell migration: integrating signals from front to back. Science (2003) 29.13
Tissue cells feel and respond to the stiffness of their substrate. Science (2005) 23.42
Tensional homeostasis and the malignant phenotype. Cancer Cell (2005) 19.30
Myofibroblasts and mechano-regulation of connective tissue remodelling. Nat Rev Mol Cell Biol (2002) 14.80
The myofibroblast: one function, multiple origins. Am J Pathol (2007) 8.64
The lamellipodium: where motility begins. Trends Cell Biol (2002) 5.70
Role of formins in actin assembly: nucleation and barbed-end association. Science (2002) 5.47
Recent developments in myofibroblast biology: paradigms for connective tissue remodeling. Am J Pathol (2012) 4.13
Increased endoplasmic reticulum stress in atherosclerotic plaques associated with acute coronary syndrome. Circulation (2007) 3.77
Tissue repair, contraction, and the myofibroblast. Wound Repair Regen (2005) 3.70
The stroma reaction myofibroblast: a key player in the control of tumor cell behavior. Int J Dev Biol (2004) 3.34
Sra-1 and Nap1 link Rac to actin assembly driving lamellipodia formation. EMBO J (2004) 3.31
Integrin signaling to the actin cytoskeleton. Curr Opin Cell Biol (2003) 3.11
Substrate rigidity regulates the formation and maintenance of tissues. Biophys J (2005) 3.08
Nonmuscle myosin IIb is involved in the guidance of fibroblast migration. Mol Biol Cell (2003) 3.02
Recruitment of the Arp2/3 complex to vinculin: coupling membrane protrusion to matrix adhesion. J Cell Biol (2002) 2.99
The dynamics and mechanics of endothelial cell spreading. Biophys J (2005) 2.76
The kinase activity of aurora B is required for kinetochore-microtubule interactions during mitosis. Curr Biol (2002) 2.68
ICAM-1-mediated, Src- and Pyk2-dependent vascular endothelial cadherin tyrosine phosphorylation is required for leukocyte transendothelial migration. J Immunol (2007) 2.66
Viscoelastic properties of individual glial cells and neurons in the CNS. Proc Natl Acad Sci U S A (2006) 2.64
Regulation of Rho GTPase crosstalk, degradation and activity by RhoGDI1. Nat Cell Biol (2010) 2.61
The making of filopodia. Curr Opin Cell Biol (2005) 2.59
Fc-receptor-mediated phagocytosis is regulated by mechanical properties of the target. J Cell Sci (2002) 2.54
Analysis of activated GAPs and GEFs in cell lysates. Methods Enzymol (2006) 2.45
The Rho GEFs LARG and GEF-H1 regulate the mechanical response to force on integrins. Nat Cell Biol (2011) 2.45
Mechanisms of force generation and transmission by myofibroblasts. Curr Opin Biotechnol (2003) 2.43
The 'invisible hand': regulation of RHO GTPases by RHOGDIs. Nat Rev Mol Cell Biol (2011) 2.39
Filopodia formation in the absence of functional WAVE- and Arp2/3-complexes. Mol Biol Cell (2006) 2.36
RhoA is required for cortical retraction and rigidity during mitotic cell rounding. J Cell Biol (2003) 2.34
Dissecting the role of Rho-mediated signaling in contractile ring formation. Mol Biol Cell (2005) 2.33
Formins: signaling effectors for assembly and polarization of actin filaments. J Cell Sci (2003) 2.31
Cell-cell mechanical communication through compliant substrates. Biophys J (2008) 2.31
Arp2/3 complex interactions and actin network turnover in lamellipodia. EMBO J (2008) 2.30
Serine phosphorylation negatively regulates RhoA in vivo. J Biol Chem (2003) 2.28
Normal and pathologic soft tissue remodeling: role of the myofibroblast, with special emphasis on liver and kidney fibrosis. Lab Invest (2003) 2.27
Differentially oriented populations of actin filaments generated in lamellipodia collaborate in pushing and pausing at the cell front. Nat Cell Biol (2008) 2.22
Characterization of the interface between normal and transformed epithelial cells. Nat Cell Biol (2009) 2.21
Rho protein crosstalk: another social network? Trends Cell Biol (2011) 2.19
Regulation of actin dynamics by WASP and WAVE family proteins. Trends Cell Biol (2004) 2.19
FMNL2 drives actin-based protrusion and migration downstream of Cdc42. Curr Biol (2012) 2.18
Smooth muscle cell plasticity: fact or fiction? Circ Res (2012) 2.18
Responses of fibroblasts to anchorage of dorsal extracellular matrix receptors. Proc Natl Acad Sci U S A (2004) 2.18
RhoA and ROCK promote migration by limiting membrane protrusions. J Biol Chem (2003) 2.17
Arterial smooth muscle cell heterogeneity: implications for atherosclerosis and restenosis development. Arterioscler Thromb Vasc Biol (2003) 2.17
Abi1 regulates the activity of N-WASP and WAVE in distinct actin-based processes. Nat Cell Biol (2005) 2.16
Simultaneous stretching and contraction of stress fibers in vivo. Mol Biol Cell (2004) 2.12
Mammary epithelial cell: influence of extracellular matrix composition and organization during development and tumorigenesis. Int J Biochem Cell Biol (2007) 2.12
Rho kinase differentially regulates phosphorylation of nonmuscle myosin II isoforms A and B during cell rounding and migration. J Biol Chem (2006) 2.07
Inhibitory signalling to the Arp2/3 complex steers cell migration. Nature (2013) 2.06
PIP(2)-PDZ domain binding controls the association of syntenin with the plasma membrane. Mol Cell (2002) 2.04
Electron tomography reveals unbranched networks of actin filaments in lamellipodia. Nat Cell Biol (2010) 2.02
Roles played by a subset of integrin signaling molecules in cadherin-based cell-cell adhesion. J Cell Biol (2004) 2.02
IRSp53 links the enterohemorrhagic E. coli effectors Tir and EspFU for actin pedestal formation. Cell Host Microbe (2009) 2.01
c-Jun is essential for organization of the epidermal leading edge. Dev Cell (2003) 2.00
Influence of type I collagen surface density on fibroblast spreading, motility, and contractility. Biophys J (2003) 1.97
Regulation of substrate adhesion dynamics during cell motility. Int J Biochem Cell Biol (2002) 1.95
Global impact of oncogenic Src on a phosphotyrosine proteome. J Proteome Res (2008) 1.94
Cytoskeletal regulation: rich in lipids. Nat Rev Mol Cell Biol (2004) 1.94
How do microtubules guide migrating cells? Nat Rev Mol Cell Biol (2002) 1.93
Actomyosin tension is required for correct recruitment of adherens junction components and zonula occludens formation. Exp Cell Res (2006) 1.91
Clustering of VASP actively drives processive, WH2 domain-mediated actin filament elongation. EMBO J (2008) 1.90
Endogenous angiotensin II induces atherosclerotic plaque vulnerability and elicits a Th1 response in ApoE-/- mice. Hypertension (2004) 1.89
N-WASP deficiency impairs EGF internalization and actin assembly at clathrin-coated pits. J Cell Sci (2005) 1.89
Dissecting the link between stress fibres and focal adhesions by CALI with EGFP fusion proteins. Nat Cell Biol (2002) 1.89
Rnd proteins function as RhoA antagonists by activating p190 RhoGAP. Curr Biol (2003) 1.84
Rap1 GTPase inhibits leukocyte transmigration by promoting endothelial barrier function. J Biol Chem (2005) 1.84
Genetic ablation of zyxin causes Mena/VASP mislocalization, increased motility, and deficits in actin remodeling. J Cell Biol (2006) 1.83
Three-dimensional arrangement of F-actin in the contractile ring of fission yeast. J Cell Biol (2007) 1.82
The NH2-terminal peptide of alpha-smooth muscle actin inhibits force generation by the myofibroblast in vitro and in vivo. J Cell Biol (2002) 1.82
Biomechanics: cell research and applications for the next decade. Ann Biomed Eng (2009) 1.81
Importance of a myosin II-containing progenitor for actomyosin ring assembly in fission yeast. Curr Biol (2002) 1.80
Focal adhesion kinase suppresses apoptosis by binding to the death domain of receptor-interacting protein. Mol Cell Biol (2004) 1.79
Catching a GEF by its tail. Trends Cell Biol (2006) 1.79
Regulation of focal complex composition and disassembly by the calcium-dependent protease calpain. J Cell Sci (2002) 1.79
XPLN, a guanine nucleotide exchange factor for RhoA and RhoB, but not RhoC. J Biol Chem (2002) 1.78
mDia2 induces the actin scaffold for the contractile ring and stabilizes its position during cytokinesis in NIH 3T3 cells. Mol Biol Cell (2008) 1.78
Regulation of mechanical interactions between fibroblasts and the substratum by stretch-activated Ca2+ entry. J Cell Sci (2003) 1.77
Crk-associated substrate tyrosine phosphorylation sites are critical for invasion and metastasis of SRC-transformed cells. Mol Cancer Res (2005) 1.77
Rho mediates the shear-enhancement of endothelial cell migration and traction force generation. Biophys J (2004) 1.77
Myosin-II reorganization during mitosis is controlled temporally by its dephosphorylation and spatially by Mid1 in fission yeast. J Cell Biol (2004) 1.76
VEGF-induced Rac1 activation in endothelial cells is regulated by the guanine nucleotide exchange factor Vav2. Exp Cell Res (2007) 1.76
Traction forces of fibroblasts are regulated by the Rho-dependent kinase but not by the myosin light chain kinase. Arch Biochem Biophys (2006) 1.76
Mechanics of neutrophil phagocytosis: experiments and quantitative models. J Cell Sci (2006) 1.75
Subsets of the major tyrosine phosphorylation sites in Crk-associated substrate (CAS) are sufficient to promote cell migration. J Biol Chem (2004) 1.74
The mechanics of neutrophils: synthetic modeling of three experiments. Biophys J (2003) 1.74
Beta and gamma-cytoplasmic actins display distinct distribution and functional diversity. J Cell Sci (2009) 1.72
The signaling and biological implications of FAK overexpression in cancer. Clin Cancer Res (2006) 1.71
Mechanics of neutrophil phagocytosis: behavior of the cortical tension. J Cell Sci (2005) 1.71
RhoG regulates endothelial apical cup assembly downstream from ICAM1 engagement and is involved in leukocyte trans-endothelial migration. J Cell Biol (2007) 1.71
RhoG signals in parallel with Rac1 and Cdc42. J Biol Chem (2002) 1.70
Building the actin cytoskeleton: filopodia contribute to the construction of contractile bundles in the lamella. J Cell Biol (2008) 1.70
Nanometer targeting of microtubules to focal adhesions. J Cell Biol (2003) 1.69
The regulation of vascular endothelial growth factor-induced microvascular permeability requires Rac and reactive oxygen species. J Biol Chem (2009) 1.69